Published in Proc Natl Acad Sci U S A on November 12, 2008
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nat Rev Immunol (2013) 2.89
T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells. Nat Immunol (2010) 2.49
SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics. Immunity (2010) 2.47
Decision checkpoints in the thymus. Nat Immunol (2010) 1.75
Alternative memory in the CD8 T cell lineage. Trends Immunol (2011) 1.60
Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethality. Blood (2015) 1.51
PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions. J Exp Med (2011) 1.47
T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harb Perspect Biol (2010) 1.45
Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol (2012) 1.35
Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk. Immunol Rev (2009) 1.32
Development of PLZF-expressing innate T cells. Curr Opin Immunol (2011) 1.28
Transcriptional control of invariant NKT cell development. Immunol Rev (2010) 1.24
Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling. J Immunol (2011) 1.14
Hallmarks of Tissue-Resident Lymphocytes. Cell (2016) 1.10
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 1.04
Where do MAIT cells fit in the family of unconventional T cells? PLoS Biol (2009) 1.02
Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function. Nat Immunol (2015) 0.99
Transcriptional regulation of NKT cell development and homeostasis. Curr Opin Immunol (2010) 0.98
A naive-like population of human CD1d-restricted T cells expressing intermediate levels of promyelocytic leukemia zinc finger. J Immunol (2011) 0.98
Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function. Proc Natl Acad Sci U S A (2014) 0.97
Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells. BMC Genomics (2009) 0.96
Autoreactive CD1b-restricted T cells: a new innate-like T-cell population that contributes to immunity against infection. Blood (2011) 0.95
Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates. FEBS J (2011) 0.94
Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development. J Immunol (2013) 0.94
PLZF Controls the Expression of a Limited Number of Genes Essential for NKT Cell Function. Front Immunol (2012) 0.92
Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient. PLoS One (2011) 0.92
A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes. J Immunol (2013) 0.91
ITK inhibitors in inflammation and immune-mediated disorders. Curr Top Med Chem (2009) 0.86
A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice. J Immunol (2012) 0.84
BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs. Proc Natl Acad Sci U S A (2015) 0.83
Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling. Sci Rep (2015) 0.82
A transgenic TCR directs the development of IL-4+ and PLZF+ innate CD4 T cells. J Immunol (2013) 0.82
Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell. J Biol Chem (2010) 0.82
Multiple layers of transcriptional regulation by PLZF in NKT-cell development. Proc Natl Acad Sci U S A (2016) 0.82
Parallels and differences between innate and adaptive lymphocytes. Nat Immunol (2016) 0.80
Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers. Immunol Rev (2014) 0.80
Role of Group 1 CD1-Restricted T Cells in Infectious Disease. Front Immunol (2015) 0.79
PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD. Cancer Res (2013) 0.78
IL-4 and IL-4 receptor expression is dispensable for the development and function of natural killer T cells. PLoS One (2013) 0.76
Lck regulates IL-10 expression in memory-like Th1 cells. Eur J Immunol (2010) 0.76
The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells. PLoS One (2016) 0.75
The MAIT conundrum - how human MAIT cells distinguish bacterial colonization from infection in mucosal barrier tissues. Immunol Lett (2017) 0.75
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The biology of NKT cells. Annu Rev Immunol (2007) 14.43
Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu Rev Immunol (2006) 4.98
The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity (2008) 4.68
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol (2008) 4.15
Homeostasis of memory T cells. Immunol Rev (2006) 3.69
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity (2007) 3.02
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity (2006) 2.77
POZ for effect--POZ-ZF transcription factors in cancer and development. Trends Cell Biol (2006) 2.62
All in the family: the BTB/POZ, KRAB, and SCAN domains. Mol Cell Biol (2001) 2.56
The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. Immunity (2006) 2.55
CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza. Immunol Rev (2006) 2.49
Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells. Nat Immunol (2002) 2.40
MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol (2005) 2.08
Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. Nat Rev Immunol (2007) 2.07
Requirements for CD8 T-cell priming, memory generation and maintenance. Curr Opin Immunol (2007) 1.91
CD1d- and MR1-restricted invariant T cells: of mice and men. Curr Opin Immunol (2006) 1.77
Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes. Immunity (2007) 1.71
NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. J Immunol (2002) 1.67
Requirements for selection of conventional and innate T lymphocyte lineages. Immunity (2007) 1.59
The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction. Immunity (2007) 1.58
ITK and IL-15 support two distinct subsets of CD8+ T cells. Proc Natl Acad Sci U S A (2006) 1.55
The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. J Immunol (2008) 1.51
On the road: progress in finding the unique pathway of invariant NKT cell differentiation. Curr Opin Immunol (2007) 1.50
Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk. Eur J Immunol (2007) 1.46
A key role for Itk in both IFN gamma and IL-4 production by NKT cells. J Immunol (2007) 1.35
Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development. J Immunol (2008) 1.32
Homeostasis and T cell regulation. Curr Opin Immunol (2004) 1.26
The role of BTB domain-containing zinc finger proteins in T cell development and function. Immunol Lett (2006) 1.23
Thymic differentiation of TCR alpha beta(+) CD8 alpha alpha(+) IELs. Immunol Rev (2007) 1.21
Pronuclear microinjection of mouse zygotes. Methods Mol Biol (2004) 1.00
H2-M3-restricted T cell response to infection. Microbes Infect (2006) 1.00
Development and selection of Valpha l4i NKT cells. Curr Top Microbiol Immunol (2007) 0.89
The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity (2008) 4.44
Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med (2005) 4.42
IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nat Immunol (2011) 4.18
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat Med (2011) 3.96
Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc Natl Acad Sci U S A (2003) 3.29
Pax5: the guardian of B cell identity and function. Nat Immunol (2007) 3.15
Bi-directional interconversion of brite and white adipocytes. Nat Cell Biol (2013) 3.08
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. Nat Immunol (2007) 2.80
Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity (2006) 2.64
Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes. J Immunol (2002) 2.54
CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors. Science (2004) 2.54
Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity (2003) 2.51
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib. Proc Natl Acad Sci U S A (2007) 2.51
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Nat Immunol (2003) 2.44
Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain. Immunol Rev (2009) 2.30
Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J (2007) 2.27
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell (2008) 2.13
Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol (2013) 2.11
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis. Proc Natl Acad Sci U S A (2008) 2.10
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity (2013) 1.89
Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity. Immunity (2005) 1.85
A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity. Proc Natl Acad Sci U S A (2008) 1.75
Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A (2002) 1.70
Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci U S A (2006) 1.68
Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol Rev (2005) 1.56
BTKbase: the mutation database for X-linked agammaglobulinemia. Hum Mutat (2006) 1.55
Comparison of a new self-gripping mesh with other fixation methods for laparoscopic hernia repair in a rat model. J Am Coll Surg (2009) 1.53
Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy. Mol Ther Nucleic Acids (2012) 1.53
Interferons limit inflammatory responses by induction of tristetraprolin. Blood (2006) 1.53
Parthenogenetic embryo-like structures in the human ovarian surface epithelium cell culture in postmenopausal women with no naturally present follicles and oocytes. Stem Cells Dev (2009) 1.52
Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation. Brain (2005) 1.51
A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development. Blood (2010) 1.50
Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes. PLoS Pathog (2009) 1.50
Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation. Nat Rev Immunol (2002) 1.49
The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival. Br J Haematol (2008) 1.47
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology (2012) 1.43
Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat Immunol (2006) 1.41
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol (2010) 1.39
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. Nucleic Acids Res (2011) 1.35
Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible. EMBO J (2004) 1.28
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol (2010) 1.28
The role of BTB domain-containing zinc finger proteins in T cell development and function. Immunol Lett (2006) 1.23
Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation. Mol Syst Biol (2011) 1.23
Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1. J Exp Med (2002) 1.23
Absence of the prion protein homologue Doppel causes male sterility. EMBO J (2002) 1.23
The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development. Adv Immunol (2004) 1.22
Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis. Am J Pathol (2006) 1.20
Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood (2008) 1.20
Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell (2004) 1.18
MicroRNA-7a regulates pancreatic β cell function. J Clin Invest (2014) 1.18
CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers. J Biol Chem (2005) 1.18
Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog (2011) 1.17
Synaptic destabilization by neuronal Nogo-A. Brain Cell Biol (2007) 1.17
Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage. Cell (2009) 1.15
Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis. J Immunol (2008) 1.15
Tec regulates platelet activation by GPVI in the absence of Btk. Blood (2003) 1.14
Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering. EMBO J (2003) 1.13
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier. J Lipid Res (2013) 1.13
The comprehensive native interactome of a fully functional tagged prion protein. PLoS One (2009) 1.13
The role of Tec family kinases in the regulation of T-helper-cell differentiation. Int Rev Immunol (2012) 1.12
Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease. Cell (2003) 1.10
Type I IFN are host modulators of strain-specific Listeria monocytogenes virulence. Cell Microbiol (2007) 1.09
Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development. J Immunol (2005) 1.09
Neurotrypsin cleaves agrin locally at the synapse. FASEB J (2008) 1.09
Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. Arthritis Rheum (2004) 1.08
Transcriptional and epigenetic regulation of CD4/CD8 lineage choice. Adv Immunol (2011) 1.08
Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB. Blood (2008) 1.08
Biological activity and biotechnological aspects of peptide nucleic acid. Adv Genet (2006) 1.07
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J (2012) 1.07
The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils. Blood (2008) 1.05
Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL. J Immunol (2009) 1.05
Intrinsic resistance of oligodendrocytes to prion infection. J Neurosci (2004) 1.04
Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver. FASEB J (2004) 1.04
Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis. J Biol Chem (2002) 1.04
Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus. J Immunol (2005) 1.03
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev Biol (2008) 1.02
Requirement of the IFN-alpha/beta-induced CXCR3 chemokine signalling for CD8+ T cell activation. Genes Cells (2002) 1.02
Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model. Lab Invest (2012) 1.02
RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation. Immunity (2011) 1.02
Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells. Proc Natl Acad Sci U S A (2011) 1.01
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release (2009) 1.01
Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia. EMBO J (2003) 1.01
Down-regulation of RXRalpha expression is essential for neutrophil development from granulocyte/monocyte progenitors. Blood (2006) 1.00
The role of Tec family kinases in myeloid cells. Int Arch Allergy Immunol (2004) 1.00