Jacques Mallet

Author PubWeight™ 91.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 2013 7.44
2 Gene networks inference using dynamic Bayesian networks. Bioinformatics 2003 2.74
3 Serotonin has a key role in pathogenesis of experimental colitis. Gastroenterology 2009 2.55
4 Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons. J Neurosci 2011 2.21
5 Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc Natl Acad Sci U S A 2003 2.19
6 Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med 2011 1.78
7 Maternal serotonin is crucial for murine embryonic development. Proc Natl Acad Sci U S A 2006 1.75
8 Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo. Proc Natl Acad Sci U S A 2006 1.74
9 No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science 2002 1.57
10 Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation. PLoS One 2009 1.53
11 Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci 2008 1.34
12 PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly. FEBS J 2005 1.23
13 Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome. FASEB J 2011 1.23
14 TIMP-1 abolishes MMP-9-dependent long-lasting long-term potentiation in the prefrontal cortex. Biol Psychiatry 2007 1.22
15 SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury. J Neurosci 2010 1.18
16 Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity. Proc Natl Acad Sci U S A 2007 1.17
17 Human retinoic acid receptor-related orphan receptor alpha1 overexpression protects neurones against oxidative stress-induced apoptosis. J Neurochem 2006 1.15
18 Non-integrating lentiviral vectors. Curr Gene Ther 2008 1.13
19 Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro. J Neurosci 2003 1.12
20 Grafts of brain-derived neurotrophic factor and neurotrophin 3-transduced primate Schwann cells lead to functional recovery of the demyelinated mouse spinal cord. J Neurosci 2005 1.09
21 A single lentivirus vector mediates doxycycline-regulated expression of transgenes in the brain. Hum Gene Ther 2004 1.08
22 Retinoid-related orphan receptor alpha controls the early steps of Purkinje cell dendritic differentiation. J Neurosci 2006 1.06
23 Recent advances in understanding serotonin regulation of cardiovascular function. Trends Mol Med 2004 1.05
24 Beta cells within single human islets originate from multiple progenitors. PLoS One 2008 1.05
25 Genome-wide association study of multiplex schizophrenia pedigrees. Am J Psychiatry 2012 1.05
26 Lentiviral-mediated targeted NF-kappaB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat. Mol Ther 2007 1.04
27 Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders. Biol Psychiatry 2008 1.01
28 Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments. J Neurosci 2007 1.01
29 Serotonin activates dendritic cell function in the context of gut inflammation. Am J Pathol 2011 0.98
30 Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice. Proc Natl Acad Sci U S A 2011 0.98
31 BDNF-induced white matter neuroprotection and stage-dependent neuronal survival following a neonatal excitotoxic challenge. Cereb Cortex 2004 0.96
32 Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter. J Gene Med 2005 0.94
33 Lentiviral vectors mediate nonimmunosuppressive rapamycin analog-induced production of secreted therapeutic factors in the brain: regulation at the level of transcription and exocytosis. Hum Gene Ther 2008 0.92
34 Lentiviral-mediated targeted transgene expression in dorsal spinal cord glia: tool for the study of glial cell implication in mechanisms underlying chronic pain development. J Neurosci Methods 2007 0.92
35 SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor. J Neurosci 2008 0.91
36 Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury. PLoS One 2010 0.88
37 Zinc finger protein 191 (ZNF191/Zfp191) is necessary to maintain neural cells as cycling progenitors. Stem Cells 2009 0.88
38 Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. J Neurochem 2006 0.88
39 A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors. PLoS One 2009 0.88
40 Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter. Nucleic Acids Res 2006 0.87
41 A novel and efficient gene transfer strategy reduces glial reactivity and improves neuronal survival and axonal growth in vitro. PLoS One 2009 0.87
42 Expression of the transcription factor Zfp191 during embryonic development in the mouse. Gene Expr Patterns 2007 0.86
43 Maternal serotonin influences cardiac function in adult offspring. FASEB J 2008 0.86
44 Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase. Mol Cell Neurosci 2003 0.86
45 Efficient myelin repair in the macaque spinal cord by autologous grafts of Schwann cells. Brain 2005 0.86
46 Optimization of transgene expression at the posttranscriptional level in neural cells: implications for gene therapy. Mol Ther 2003 0.86
47 Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors. Glia 2012 0.85
48 The tissue-specific methylation of the human tyrosine hydroxylase gene reveals new regulatory elements in the first exon. J Neurochem 2005 0.85
49 Silencing of choline acetyltransferase expression by lentivirus-mediated RNA interference in cultured cells and in the adult rodent brain. J Neurosci Res 2009 0.85
50 Differential amplification of intron-containing transcripts reveals long term potentiation-associated up-regulation of specific Pde10A phosphodiesterase splice variants. J Biol Chem 2004 0.85
51 Abnormal TDP-43 and FUS proteins in muscles of sporadic IBM: similarities in a TARDBP-linked ALS patient. J Neurol Neurosurg Psychiatry 2010 0.84
52 1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase. J Neurosci Res 2006 0.84
53 ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons. Mol Cell Biol 2005 0.84
54 Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge. J Neurosci Res 2006 0.83
55 Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system. Mol Cell Neurosci 2002 0.83
56 Expression of PRiMA in the mouse brain: membrane anchoring and accumulation of 'tailed' acetylcholinesterase. Eur J Neurosci 2003 0.83
57 Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia. Mol Cell Neurosci 2005 0.82
58 Neonatal handling prevents the effects of phencyclidine in an animal model of negative symptoms of schizophrenia. Biol Psychiatry 2006 0.81
59 More than one way to toy with ChAT and VAChT. J Physiol Paris 2001 0.81
60 Tet system in the brain: transgenic rats and lentiviral vectors approach. Genesis 2009 0.81
61 Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine. J Neurochem 2002 0.79
62 Transforming growth factor beta1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice. Mol Cell Neurosci 2003 0.79
63 Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease. Neurobiol Dis 2005 0.79
64 Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev 2011 0.79
65 Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. PLoS One 2013 0.79
66 Mammalian prenatal development: the influence of maternally derived molecules. Bioessays 2009 0.79
67 Neurotensin induces tyrosine hydroxylase gene activation through nitric oxide and protein kinase C signaling pathways. Mol Pharmacol 2002 0.78
68 Gene transfer into the central and peripheral nervous system: applications for the treatment of neurodegenerative diseases and peripheral neuropathies. Biotechnol Genet Eng Rev 2003 0.78
69 Molecular Cloning of Forebrain mRNAs which are Modulated by Sleep Deprivation. Eur J Neurosci 1990 0.78
70 Mass spectrometry reveals changes in MHC I antigen presentation after lentivector expression of a gene regulation system. Mol Ther Nucleic Acids 2013 0.78
71 Gi/Go protein-dependent presynaptic mechanisms are involved in clozapine-induced down-regulation of tyrosine hydroxylase in PC12 cells. J Neurosci Res 2005 0.78
72 Behavioural Effect of Engineered Cells that Synthesize l-dopa or Dopamine after Grafting into the Rat Neostriatum. Eur J Neurosci 1990 0.78
73 The extract of Ginkgo biloba EGb 761 reactivates a juvenile profile in the skeletal muscle of sarcopenic rats by transcriptional reprogramming. PLoS One 2009 0.77
74 Genome-scan for bipolar disorder with sib-pair families in the Sardinian population: a new susceptibility locus on chromosome 1p22-p21? Am J Med Genet B Neuropsychiatr Genet 2010 0.77
75 Adenoviral retrograde gene transfer in motoneurons is greatly enhanced by prior intramuscular inoculation with botulinum toxin. Hum Gene Ther 2002 0.77
76 Lentiviral-mediated silencing of glial fibrillary acidic protein and vimentin promotes anatomical plasticity and functional recovery after spinal cord injury. J Neurosci Res 2014 0.77
77 Obsessive compulsive disorder--prevalence in Xhosa-speaking schizophrenia patients. S Afr Med J 2005 0.77
78 Tyrosine hydroxylase mRNA and protein are down-regulated by chronic clozapine in both the mesocorticolimbic and the nigrostriatal systems. J Neurosci Res 2003 0.77
79 Post-genomic era and gene discovery for psychiatric diseases: there is a new art of the trade? The example of the HUMTH01 microsatellite in the Tyrosine Hydroxylase gene. Mol Neurobiol 2002 0.77
80 Paradoxical methylation of the tyrosine hydroxylase gene in mouse preimplantation embryos. Genomics 2002 0.77
81 Integration of genetically modified adult astrocytes into the lesioned rat spinal cord. J Neurosci Res 2006 0.77
82 Long-term fate of human telencephalic progenitor cells grafted into the adult mouse brain: effects of previous amplification in vitro. J Neurosci Res 2002 0.76
83 Role of Dopaminergic D2 Receptors in the Regulation of Glutamic Acid Decarboxylase Messenger RNA in the Striatum of the Rat. Eur J Neurosci 1992 0.76
84 Quantification of transcriptional activities of reporter gene constructs in primary cultures of sympathetic neurons. J Neurosci Res 2003 0.76
85 Manic-depressive illness: an association study with the inositol polyphosphate 1-phosphatase and serotonin transporter genes. Psychiatr Genet 2002 0.75
86 CAG repeat polymorphisms in KCNN3 (HSKCa3) and PPP2R2B show no association or linkage to schizophrenia. Am J Med Genet B Neuropsychiatr Genet 2003 0.75
87 Transplantation of human adult astrocytes: efficiency and safety requirements for an autologous gene therapy. J Neurosci Res 2003 0.75
88 The Budapest Meeting 2005 intensified networking on ethics of science: the case of reproductive cloning, germline gene therapy and human dignity. Sci Eng Ethics 2006 0.75
89 cDNA libraries from a low amount of cells. Methods Mol Biol 2003 0.75
90 Positive and negative symptoms in affected sib pairs with schizophrenia: implications for genetic studies in an African Xhosa sample. Schizophr Res 2005 0.75
91 [Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis]. J Soc Biol 2004 0.75