| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium.
|
Proc Natl Acad Sci U S A
|
2006
|
2.45
|
|
2
|
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.
|
J Clin Invest
|
2008
|
2.40
|
|
3
|
Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin.
|
J Biol Chem
|
2001
|
2.14
|
|
4
|
A blue-blocking intraocular lens should be used in cataract surgery.
|
Arch Ophthalmol
|
2005
|
1.97
|
|
5
|
Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement.
|
Angew Chem Int Ed Engl
|
2002
|
1.95
|
|
6
|
Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.
|
Proc Natl Acad Sci U S A
|
2004
|
1.80
|
|
7
|
The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.
|
Proc Natl Acad Sci U S A
|
2007
|
1.78
|
|
8
|
SOD2 knockdown mouse model of early AMD.
|
Invest Ophthalmol Vis Sci
|
2007
|
1.77
|
|
9
|
Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate.
|
Proc Natl Acad Sci U S A
|
2005
|
1.75
|
|
10
|
The susceptibility of the retina to photochemical damage from visible light.
|
Prog Retin Eye Res
|
2011
|
1.67
|
|
11
|
Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin.
|
J Biol Chem
|
2005
|
1.65
|
|
12
|
Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation.
|
Biochemistry
|
2006
|
1.63
|
|
13
|
Retinal pigment epithelium lipofuscin proteomics.
|
Mol Cell Proteomics
|
2008
|
1.50
|
|
14
|
Complement activation by bisretinoid constituents of RPE lipofuscin.
|
Invest Ophthalmol Vis Sci
|
2008
|
1.47
|
|
15
|
Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration.
|
Proc Natl Acad Sci U S A
|
2010
|
1.40
|
|
16
|
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
|
J Biol Chem
|
2009
|
1.33
|
|
17
|
Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli.
|
Invest Ophthalmol Vis Sci
|
2009
|
1.32
|
|
18
|
Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells.
|
Exp Eye Res
|
2005
|
1.31
|
|
19
|
A2-rhodopsin: a new fluorophore isolated from photoreceptor outer segments.
|
Org Biomol Chem
|
2003
|
1.31
|
|
20
|
Quantitative fundus autofluorescence in recessive Stargardt disease.
|
Invest Ophthalmol Vis Sci
|
2014
|
1.27
|
|
21
|
Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin.
|
Exp Eye Res
|
2005
|
1.26
|
|
22
|
A method of drusen measurement based on the geometry of fundus reflectance.
|
Biomed Eng Online
|
2003
|
1.19
|
|
23
|
Photoreceptor cell degeneration in Abcr (-/-) mice.
|
Adv Exp Med Biol
|
2010
|
1.18
|
|
24
|
Quantitative fundus autofluorescence in healthy eyes.
|
Invest Ophthalmol Vis Sci
|
2013
|
1.11
|
|
25
|
Comparison of near-infrared and short-wavelength autofluorescence in retinitis pigmentosa.
|
Invest Ophthalmol Vis Sci
|
2013
|
1.09
|
|
26
|
Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway.
|
Biochemistry
|
2007
|
1.07
|
|
27
|
Photographic patterns in macular images: representation by a mathematical model.
|
J Biomed Opt
|
2004
|
1.06
|
|
28
|
Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells.
|
Photochem Photobiol
|
2005
|
1.05
|
|
29
|
Autofluorescence characteristics of normal foveas and reconstruction of foveal autofluorescence from limited data subsets.
|
Invest Ophthalmol Vis Sci
|
2005
|
1.05
|
|
30
|
Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin.
|
Exp Eye Res
|
2009
|
1.05
|
|
31
|
Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments.
|
Chirality
|
2004
|
1.00
|
|
32
|
Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells.
|
Free Radic Biol Med
|
2012
|
1.00
|
|
33
|
Rdh12 activity and effects on retinoid processing in the murine retina.
|
J Biol Chem
|
2009
|
0.99
|
|
34
|
The proteasome: a target of oxidative damage in cultured human retina pigment epithelial cells.
|
Invest Ophthalmol Vis Sci
|
2008
|
0.99
|
|
35
|
Quantitative fundus autofluorescence and optical coherence tomography in best vitelliform macular dystrophy.
|
Invest Ophthalmol Vis Sci
|
2014
|
0.97
|
|
36
|
Indirect antioxidant protection against photooxidative processes initiated in retinal pigment epithelial cells by a lipofuscin pigment.
|
Rejuvenation Res
|
2006
|
0.97
|
|
37
|
A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration.
|
PLoS One
|
2012
|
0.97
|
|
38
|
Photooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity.
|
Vision Res
|
2009
|
0.96
|
|
39
|
Mechanisms involved in A2E oxidation.
|
Exp Eye Res
|
2008
|
0.96
|
|
40
|
Toward an understanding of bisretinoid autofluorescence bleaching and recovery.
|
Invest Ophthalmol Vis Sci
|
2012
|
0.95
|
|
41
|
A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine.
|
Invest Ophthalmol Vis Sci
|
2011
|
0.95
|
|
42
|
Fundus autofluorescence imaging in a patient with rapidly developing scotoma.
|
Retin Cases Brief Rep
|
2012
|
0.95
|
|
43
|
Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells.
|
J Biol Chem
|
2009
|
0.92
|
|
44
|
Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
|
Biochim Biophys Acta
|
2011
|
0.91
|
|
45
|
Photo-products of retinal pigment epithelial bisretinoids react with cellular thiols.
|
Mol Vis
|
2011
|
0.90
|
|
46
|
Fundus autofluorescence findings in a mouse model of retinal detachment.
|
Invest Ophthalmol Vis Sci
|
2012
|
0.90
|
|
47
|
Scotopic sensitivity and color vision with a blue-light-absorbing intraocular lens.
|
J Cataract Refract Surg
|
2007
|
0.89
|
|
48
|
A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
|
Invest Ophthalmol Vis Sci
|
2013
|
0.87
|
|
49
|
Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light.
|
Apoptosis
|
2009
|
0.86
|
|
50
|
Distinct characteristics of inferonasal fundus autofluorescence patterns in stargardt disease and retinitis pigmentosa.
|
Invest Ophthalmol Vis Sci
|
2013
|
0.86
|
|
51
|
Enzymatic degradation of A2E, a retinal pigment epithelial lipofuscin bisretinoid.
|
J Am Chem Soc
|
2011
|
0.85
|
|
52
|
OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore.
|
Photochem Photobiol
|
2008
|
0.85
|
|
53
|
Light damage in Abca4 and Rpe65rd12 mice.
|
Invest Ophthalmol Vis Sci
|
2014
|
0.84
|
|
54
|
Visualization of the optic fissure in short-wavelength autofluorescence images of the fundus.
|
Invest Ophthalmol Vis Sci
|
2012
|
0.83
|
|
55
|
Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases.
|
J Control Release
|
2013
|
0.83
|
|
56
|
Medical bioremediation: prospects for the application of microbial catabolic diversity to aging and several major age-related diseases.
|
Ageing Res Rev
|
2005
|
0.82
|
|
57
|
Inner retina remodeling in a mouse model of stargardt-like macular dystrophy (STGD3).
|
Invest Ophthalmol Vis Sci
|
2009
|
0.81
|
|
58
|
Synthesis of antioxidants for prevention of age-related macular degeneration.
|
J Nat Prod
|
2013
|
0.81
|
|
59
|
Early changes in gene expression induced by blue light irradiation of A2E-laden retinal pigment epithelial cells.
|
Acta Ophthalmol
|
2013
|
0.80
|
|
60
|
Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells.
|
Proc Natl Acad Sci U S A
|
2007
|
0.79
|
|
61
|
Chlorophyll derivatives as visual pigments for super vision in the red.
|
Photochem Photobiol Sci
|
2007
|
0.78
|
|
62
|
Photochemistry of A1E, a retinoid with a conjugated pyridinium moiety: competition between pericyclic photooxygenation and pericyclization.
|
J Am Chem Soc
|
2004
|
0.77
|
|
63
|
Light filtering in a retinal pigment epithelial cell culture model.
|
Optom Vis Sci
|
2011
|
0.76
|
|
64
|
MULTIMODAL IMAGING OF DISEASE-ASSOCIATED PIGMENTARY CHANGES IN RETINITIS PIGMENTOSA.
|
Retina
|
2016
|
0.76
|
|
65
|
DFPE, partially fluorinated ether: a novel approach for experimental intravitreal tamponade.
|
Retina
|
2013
|
0.76
|
|
66
|
Impairment of the ubiquitin-proteasome pathway in RPE alters the expression of inflammation related genes.
|
Adv Exp Med Biol
|
2014
|
0.75
|
|
67
|
MULTIMODAL IMAGING OF DISEASE-ASSOCIATED PIGMENTARY CHANGES IN RETINITIS PIGMENTOSA.
|
Retina
|
2016
|
0.75
|