Actin cross-linking and inhibition of the actomyosin motor.

PubWeight™: 1.06‹?› | Rank: Top 10%

🔗 View Article (PMID 11772006)

Published in Biochemistry on January 08, 2002

Authors

Eldar Kim1, Elena Bobkova, György Hegyi, Andras Muhlrad, Emil Reisler

Author Affiliations

1: Department of Chemistry and Biochemistry and Molecular Biology Institute, University of California, Los Angeles, California 90095, USA.

Articles citing this

Transglutaminases: nature's biological glues. Biochem J (2002) 3.42

Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J (2004) 3.21

Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60

Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis (2008) 1.24

The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proc Natl Acad Sci U S A (2005) 1.18

Actin filaments as tension sensors. Curr Biol (2012) 1.18

Muscle disuse alters skeletal muscle contractile function at the molecular and cellular levels in older adult humans in a sex-specific manner. J Physiol (2014) 1.02

F-actin structure destabilization and DNase I binding loop: fluctuations mutational cross-linking and electron microscopy analysis of loop states and effects on F-actin. J Mol Biol (2009) 0.92

Bending flexibility of actin filaments during motor-induced sliding. Biophys J (2008) 0.85

Multiple crystal structures of actin dimers and their implications for interactions in the actin filament. Acta Crystallogr D Biol Crystallogr (2008) 0.82

Functional effects of nemaline myopathy mutations on human skeletal alpha-actin. J Biol Chem (2008) 0.81

Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes. J Biol Chem (2009) 0.79

F-actin dismantling through a redox-driven synergy between Mical and cofilin. Nat Cell Biol (2016) 0.76

G146V mutation at the hinge region of actin reveals a myosin class-specific requirement of actin conformations for motility. J Biol Chem (2012) 0.76

Articles by these authors

The Actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin. J Biol Chem (2006) 1.82

Actin filament severing by cofilin. J Mol Biol (2006) 1.82

Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization. Proc Natl Acad Sci U S A (2004) 1.70

ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments. J Cell Biol (2003) 1.68

Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60

Cooperative effects of cofilin (ADF) on actin structure suggest allosteric mechanism of cofilin function. J Mol Biol (2005) 1.50

Structural effects of cofilin on longitudinal contacts in F-actin. J Mol Biol (2002) 1.50

Cofilin-linked changes in actin filament flexibility promote severing. Biophys J (2011) 1.47

Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis. J Mol Biol (2004) 1.30

Structure and dynamics of the actin filament. Biochemistry (2005) 1.28

Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc Natl Acad Sci U S A (2008) 1.25

Cofilin (ADF) affects lateral contacts in F-actin. J Mol Biol (2004) 1.24

The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proc Natl Acad Sci U S A (2005) 1.18

Atomic force microscopy reveals drebrin induced remodeling of f-actin with subnanometer resolution. Nano Lett (2010) 1.15

Locking the hydrophobic loop 262-274 to G-actin surface by a disulfide bridge prevents filament formation. Biochemistry (2002) 1.13

Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol (2008) 1.09

Formation and destabilization of actin filaments with tetramethylrhodamine-modified actin. Biophys J (2004) 1.06

Solution properties of tetramethylrhodamine-modified G-actin. Biophys J (2003) 1.05

Characterization of the enzymatic activity of the actin cross-linking domain from the Vibrio cholerae MARTX Vc toxin. J Biol Chem (2007) 1.04

Identification of cation-binding sites on actin that drive polymerization and modulate bending stiffness. Proc Natl Acad Sci U S A (2012) 1.01

Severing of F-actin by yeast cofilin is pH-independent. Cell Motil Cytoskeleton (2006) 1.00

Structural reorganization of proteins revealed by radiolysis and mass spectrometry: G-actin solution structure is divalent cation dependent. Biochemistry (2003) 0.99

Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data. Proc Natl Acad Sci U S A (2007) 0.98

Multiple forms of Spire-actin complexes and their functional consequences. J Biol Chem (2012) 0.98

Inorganic phosphate regulates the binding of cofilin to actin filaments. FEBS J (2006) 0.97

Antagonistic effects of cofilin, beryllium fluoride complex, and phalloidin on subdomain 2 and nucleotide-binding cleft in F-actin. Biophys J (2006) 0.97

Mapping of drebrin binding site on F-actin. J Mol Biol (2010) 0.96

Hydrophobic loop dynamics and actin filament stability. Biochemistry (2006) 0.94

Conformational dynamics of loop 262-274 in G- and F-actin. Biochemistry (2006) 0.93

F-actin structure destabilization and DNase I binding loop: fluctuations mutational cross-linking and electron microscopy analysis of loop states and effects on F-actin. J Mol Biol (2009) 0.92

Bax inhibitor 1 increases cell adhesion through actin polymerization: involvement of calcium and actin binding. Mol Cell Biol (2010) 0.89

Conformation and dynamics of the SH1-SH2 helix in scallop myosin. Biochemistry (2003) 0.89

A nucleotide state-sensing region on actin. J Biol Chem (2010) 0.88

Effects of binding factors on structural elements in F-actin. Biochemistry (2009) 0.88

para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor. Angew Chem Int Ed Engl (2014) 0.88

Antiparallel dimer and actin assembly. Biochemistry (2010) 0.87

Structural states and dynamics of the D-loop in actin. Biophys J (2012) 0.87

Polycation induced actin bundles. Biophys Chem (2011) 0.86

Drebrin-induced stabilization of actin filaments. J Biol Chem (2013) 0.86

Actin hydrophobic loop 262-274 and filament nucleation and elongation. J Mol Biol (2007) 0.85

Mapping the interaction of cofilin with subdomain 2 on actin. Biochemistry (2007) 0.85

LL-37 induces polymerization and bundling of actin and affects actin structure. PLoS One (2012) 0.84

Myosin binding surface on actin probed by hydroxyl radical footprinting and site-directed labels. J Mol Biol (2011) 0.84

Conformational dynamics of the SH1-SH2 helix in the transition states of myosin subfragment-1. Biophys J (2002) 0.84

ATP and ADP actin states. Biopolymers (2013) 0.84

The actin-binding domain of cortactin is dynamic and unstructured and affects lateral and longitudinal contacts in F-actin. Cell Motil Cytoskeleton (2009) 0.84

Bioactive pseudopeptidic analogues and cyclostereoisomers of osteogenic growth peptide C-terminal pentapeptide, OGP(10-14). J Med Chem (2002) 0.83

Cosolvent-induced aggregation inhibits myosin ATPase activity by stabilizing the predominant transition intermediate. Biochemistry (2003) 0.82

Molecular cooperativity of drebrin1-300 binding and structural remodeling of F-actin. Biophys J (2012) 0.82

Multiple crystal structures of actin dimers and their implications for interactions in the actin filament. Acta Crystallogr D Biol Crystallogr (2008) 0.82

Drebrin inhibits cofilin-induced severing of F-actin. Cytoskeleton (Hoboken) (2014) 0.82

Chemical decoupling of ATPase activation and force production from the contractile cycle in myosin by steric hindrance of lever-arm movement. Biophys J (2003) 0.81

Polyamine-induced bundling of F-actin. J Phys Chem B (2006) 0.81

Cofilin-induced changes in F-actin detected via cross-linking with benzophenone-4-maleimide. Biochemistry (2013) 0.80

Correlative nanoscale imaging of actin filaments and their complexes. Nanoscale (2013) 0.79

Azidoblebbistatin, a photoreactive myosin inhibitor. Proc Natl Acad Sci U S A (2012) 0.79

Thin filament regulation and ionic interactions between the N-terminal region in actin and troponin. Biophys J (2002) 0.78

The regulation of subtilisin-cleaved actin by tropomyosin/troponin. J Biol Chem (2002) 0.77

Nanostructured self-assembly of inverted formin 2 (INF2) and F-actin-INF2 complexes revealed by atomic force microscopy. Langmuir (2014) 0.75

Insights into actomyosin interactions from actin mutations. Results Probl Cell Differ (2002) 0.75

Cross-linked long-pitch actin dimer forms stoichiometric complexes with gelsolin segment 1 and/or deoxyribonuclease I that nonproductively interact with myosin subfragment 1. Biochemistry (2008) 0.75