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Conformational dynamics of actin: effectors and implications for biological function. Cytoskeleton (Hoboken) (2010) 1.02

Crystallographic conformers of actin in a biologically active bundle of filaments. J Mol Biol (2007) 0.93

F-actin structure destabilization and DNase I binding loop: fluctuations mutational cross-linking and electron microscopy analysis of loop states and effects on F-actin. J Mol Biol (2009) 0.92

Effects of binding factors on structural elements in F-actin. Biochemistry (2009) 0.88

Structural states and dynamics of the D-loop in actin. Biophys J (2012) 0.87

Actin isoform-specific conformational differences observed with hydrogen/deuterium exchange and mass spectrometry. J Biol Chem (2009) 0.85

Actin hydrophobic loop 262-274 and filament nucleation and elongation. J Mol Biol (2007) 0.85

ATP and ADP actin states. Biopolymers (2013) 0.84

Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 7.29

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation. Proc Natl Acad Sci U S A (2008) 5.06

A new spin on protein dynamics. Trends Biochem Sci (2002) 3.72

Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking. Adv Protein Chem (2003) 3.28

Protein structures forming the shell of primitive bacterial organelles. Science (2005) 3.20

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. Nat Struct Mol Biol (2006) 2.68

Sugar binding induces an outward facing conformation of LacY. Proc Natl Acad Sci U S A (2007) 2.66

Multiquantum EPR spectroscopy of spin-labeled arrestin K267C at 35 GHz. Biophys J (2005) 2.50

Why don't they listen? Adherence to recommendations of infectious disease consultations. Clin Infect Dis (2004) 2.13

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit. Proc Natl Acad Sci U S A (2011) 2.10

Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci (2007) 2.01

Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA. Biochemistry (2004) 2.00

Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study. Biochemistry (2002) 1.99

Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin. Proc Natl Acad Sci U S A (2006) 1.94

Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme. Protein Sci (2007) 1.87

Sequence of late molecular events in the activation of rhodopsin. Proc Natl Acad Sci U S A (2007) 1.85

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data. Gut (2010) 1.83

The Actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin. J Biol Chem (2006) 1.82

Actin filament severing by cofilin. J Mol Biol (2006) 1.82

Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization. Proc Natl Acad Sci U S A (2004) 1.70

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins. Protein Sci (2009) 1.68

ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments. J Cell Biol (2003) 1.68

Structure and function of the visual arrestin oligomer. EMBO J (2007) 1.66

Site-directed spin labeling of a genetically encoded unnatural amino acid. Proc Natl Acad Sci U S A (2009) 1.65

Motion of spin label side chains in cellular retinol-binding protein: correlation with structure and nearest-neighbor interactions in an antiparallel beta-sheet. Biochemistry (2004) 1.62

Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60

Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins. Protein Sci (2009) 1.60

Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biol (2004) 1.59

Phase I clinical trial of the chimeric anti-mesothelin monoclonal antibody MORAb-009 in patients with mesothelin-expressing cancers. Clin Cancer Res (2010) 1.59

Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe. Nucleic Acids Res (2006) 1.57

Multifrequency electron spin resonance study of the dynamics of spin labeled T4 lysozyme. J Phys Chem B (2010) 1.53

Conformational states and dynamics of rhodopsin in micelles and bilayers. Biochemistry (2006) 1.51

Cooperative effects of cofilin (ADF) on actin structure suggest allosteric mechanism of cofilin function. J Mol Biol (2005) 1.50

Structural effects of cofilin on longitudinal contacts in F-actin. J Mol Biol (2002) 1.50

Cofilin-linked changes in actin filament flexibility promote severing. Biophys J (2011) 1.47

Accessibility of nitroxide side chains: absolute Heisenberg exchange rates from power saturation EPR. Biophys J (2005) 1.44

Arrangement of subunits and ordering of beta-strands in an amyloid sheet. Nat Struct Biol (2002) 1.43

Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy. Proc Natl Acad Sci U S A (2011) 1.41

Audit of acute exacerbations of chronic obstructive pulmonary disease at Waitemata District Health Board, New Zealand. N Z Med J (2013) 1.40

Functionally distinct NEAT (NEAr Transporter) domains within the Staphylococcus aureus IsdH/HarA protein extract heme from methemoglobin. J Biol Chem (2008) 1.39

Solution structure of the NEAT (NEAr Transporter) domain from IsdH/HarA: the human hemoglobin receptor in Staphylococcus aureus. J Mol Biol (2006) 1.37

A model for the solution structure of the rod arrestin tetramer. Structure (2008) 1.37

Technological advances in site-directed spin labeling of proteins. Curr Opin Struct Biol (2013) 1.36

Monitoring RNA base structure and dynamics using site-directed spin labeling. Biochemistry (2003) 1.36

Mapping of the docking of SecA onto the chaperone SecB by site-directed spin labeling: insight into the mechanism of ligand transfer during protein export. J Mol Biol (2005) 1.34

Measurements of DNA lengths remaining in a viral capsid after osmotically suppressed partial ejection. Biophys J (2004) 1.34

Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway. Proc Natl Acad Sci U S A (2006) 1.33

Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. Proc Natl Acad Sci U S A (2004) 1.32

Cofilin induced conformational changes in F-actin expose subdomain 2 to proteolysis. J Mol Biol (2004) 1.30

Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins. J Biol Chem (2011) 1.30

Structure and dynamics of the actin filament. Biochemistry (2005) 1.28

Insights from multiple structures of the shell proteins from the beta-carboxysome. Protein Sci (2009) 1.27

Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc Natl Acad Sci U S A (2008) 1.25

Cofilin (ADF) affects lateral contacts in F-actin. J Mol Biol (2004) 1.24

Conformation of receptor-bound visual arrestin. Proc Natl Acad Sci U S A (2012) 1.24

Structural biology: A moving story of receptors. Nature (2008) 1.22

Pulsed ESR dipolar spectroscopy for distance measurements in immobilized spin labeled proteins in liquid solution. J Am Chem Soc (2012) 1.21

Effects of a multidisciplinary, post-discharge continuance of care intervention on quality of life, discharge satisfaction, and hospital length of stay: a randomized controlled trial. Int J Qual Health Care (2005) 1.19

The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proc Natl Acad Sci U S A (2005) 1.18

Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer. Gynecol Oncol (2013) 1.18

Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins. Proc Natl Acad Sci U S A (2007) 1.17

Ion-dependent polymerization differences between mammalian beta- and gamma-nonmuscle actin isoforms. J Biol Chem (2010) 1.15

Atomic force microscopy reveals drebrin induced remodeling of f-actin with subnanometer resolution. Nano Lett (2010) 1.15

Importance of Vp1 calcium-binding residues in assembly, cell entry, and nuclear entry of simian virus 40. J Virol (2003) 1.15

In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment. Hum Mol Genet (2009) 1.13

Locking the hydrophobic loop 262-274 to G-actin surface by a disulfide bridge prevents filament formation. Biochemistry (2002) 1.13

Phosphorylation triggers domain separation in the DNA binding response regulator NarL. Biochemistry (2003) 1.13

The role of arrestin alpha-helix I in receptor binding. J Mol Biol (2009) 1.10

Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation. Biochemistry (2002) 1.10

Acceleration of yeast actin polymerization by yeast Arp2/3 complex does not require an Arp2/3-activating protein. J Biol Chem (2005) 1.10

Resolving Conformational and Rotameric Exchange in Spin-Labeled Proteins Using Saturation Recovery EPR. Appl Magn Reson (2010) 1.10

Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol (2008) 1.09

Conformational analysis of a nitroxide side chain in an α-helix with density functional theory. J Phys Chem B (2010) 1.08

Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein. J Mol Biol (2002) 1.08

Effect of the substitution of muscle actin-specific subdomain 1 and 2 residues in yeast actin on actin function. J Biol Chem (2006) 1.07

High-pressure EPR reveals conformational equilibria and volumetric properties of spin-labeled proteins. Proc Natl Acad Sci U S A (2011) 1.07

Actin cross-linking and inhibition of the actomyosin motor. Biochemistry (2002) 1.06

Formation and destabilization of actin filaments with tetramethylrhodamine-modified actin. Biophys J (2004) 1.06

Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. J Mol Biol (2005) 1.05

The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs). Protein Sci (2003) 1.05

Solution properties of tetramethylrhodamine-modified G-actin. Biophys J (2003) 1.05

Sites of interaction of a precursor polypeptide on the export chaperone SecB mapped by site-directed spin labeling. J Mol Biol (2006) 1.05

Vinculin nucleates actin polymerization and modifies actin filament structure. J Biol Chem (2009) 1.04

Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin. Biochemistry (2012) 1.04

Characterization of the enzymatic activity of the actin cross-linking domain from the Vibrio cholerae MARTX Vc toxin. J Biol Chem (2007) 1.04

Accessibility and dynamics of nitroxide side chains in T4 lysozyme measured by saturation recovery EPR. Biophys J (2005) 1.03