PubRank

Robert E Hammer

Author PubWeight™ 143.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metab 2007 9.62
2 A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 2007 6.64
3 White fat progenitor cells reside in the adipose vasculature. Science 2008 6.49
4 Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem 2002 5.89
5 Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Nature 2003 5.19
6 Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. Proc Natl Acad Sci U S A 2005 4.56
7 Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci U S A 2008 4.45
8 Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 2002 3.85
9 Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice. J Clin Invest 2006 3.54
10 Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 2005 3.25
11 Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci U S A 2002 3.09
12 Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci U S A 2002 3.03
13 Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron 2003 2.73
14 Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis. J Clin Invest 2004 2.66
15 Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proc Natl Acad Sci U S A 2004 2.62
16 Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Science 2008 2.44
17 Experimental control of pancreatic development and maintenance. Proc Natl Acad Sci U S A 2002 2.20
18 Autoimmune epididymoorchitis is essential to the pathogenesis of male-specific spondylarthritis in HLA-B27-transgenic rats. Arthritis Rheum 2012 2.10
19 Hyperactivated sperm motility driven by CatSper2 is required for fertilization. Proc Natl Acad Sci U S A 2003 2.07
20 Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest 2005 2.03
21 Low blood pressure in endothelial cell-specific endothelin 1 knockout mice. Hypertension 2010 1.91
22 The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. J Neurosci 2011 1.87
23 Extracellular domains of alpha-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels. J Neurosci 2005 1.87
24 Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. Mol Endocrinol 2008 1.85
25 Self renewal, expansion, and transfection of rat spermatogonial stem cells in culture. Proc Natl Acad Sci U S A 2005 1.83
26 Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. Cell Metab 2009 1.79
27 Production of transgenic rats by lentiviral transduction of male germ-line stem cells. Proc Natl Acad Sci U S A 2002 1.68
28 Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proc Natl Acad Sci U S A 2009 1.68
29 Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility. J Clin Invest 2006 1.66
30 CDK5RAP2 regulates centriole engagement and cohesion in mice. Dev Cell 2010 1.61
31 Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice. J Lipid Res 2008 1.61
32 Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family. J Neurosci 2006 1.61
33 Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem 2003 1.56
34 Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Hum Mol Genet 2005 1.56
35 Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs. Proc Natl Acad Sci U S A 2004 1.55
36 Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat. J Neurosci 2004 1.55
37 Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. EMBO J 2006 1.53
38 Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J 2006 1.51
39 Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure. J Biol Chem 2002 1.47
40 The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. Dev Biol 2005 1.45
41 Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene. Trends Endocrinol Metab 2004 1.39
42 Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proc Natl Acad Sci U S A 2010 1.38
43 Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver. J Biol Chem 2003 1.37
44 Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase. Proc Natl Acad Sci U S A 2012 1.37
45 Heritable and stable gene knockdown in rats. Proc Natl Acad Sci U S A 2006 1.26
46 Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. J Neurosci 2006 1.26
47 Defining the spermatogonial stem cell. Dev Biol 2004 1.23
48 Additional human beta2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats. Arthritis Rheum 2006 1.21
49 A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proc Natl Acad Sci U S A 2003 1.19
50 Sohlh2 knockout mice are male-sterile because of degeneration of differentiating type A spermatogonia. Stem Cells 2008 1.15
51 Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol. Mol Cell Biol 2003 1.15
52 dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Dev Biol 2003 1.12
53 Fasting-induced hypothermia and reduced energy production in mice lacking acetyl-CoA synthetase 2. Cell Metab 2009 1.11
54 ApoE receptor 2 controls neuronal survival in the adult brain. Curr Biol 2006 1.08
55 Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development. Dev Biol 2003 1.08
56 DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory. J Biol Chem 2010 1.07
57 Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol Cell Biol 2004 1.05
58 Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells. EMBO J 2007 1.05
59 Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis. J Biol Chem 2010 1.03
60 Sterile testis complementation with spermatogonial lines restores fertility to DAZL-deficient rats and maximizes donor germline transmission. PLoS One 2009 1.02
61 C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. J Biol Chem 2004 1.01
62 Male and female germline specific expression of an EGFP reporter gene in a unique strain of transgenic rats. Dev Biol 2005 0.94
63 Characterization of a Dazl-GFP germ cell-specific reporter. Genesis 2009 0.93
64 Neuropeptide B-deficient mice demonstrate hyperalgesia in response to inflammatory pain. Proc Natl Acad Sci U S A 2005 0.92
65 RNA amplification and transcriptional profiling for analysis of stem cell populations. Genesis 2003 0.92
66 Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Mol Neurodegener 2014 0.91
67 Glyceroneogenesis comes of age. FASEB J 2002 0.90
68 APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife 2013 0.90
69 Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity. Dev Biol 2009 0.87
70 Dlx5/6-enhancer directed expression of Cre recombinase in the pharyngeal arches and brain. Genesis 2003 0.87
71 Regulation of cytosolic phosphoenolpyruvate carboxykinase gene expression in adipocytes. Biochimie 2003 0.85
72 Induction of hepatocyte proliferation and death by modulation of T-Antigen expression. Oncogene 2003 0.79
73 Pathogenesis of autosomal dominant hereditary spastic paraplegia (SPG6) revealed by a rat model. J Neuropathol Exp Neurol 2013 0.75