Published in J Appl Physiol (1985) on February 01, 2002
Pathophysiology of sleep apnea. Physiol Rev (2010) 4.69
Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension. Ann Intern Med (2009) 2.25
Mechanisms of vascular damage in obstructive sleep apnea. Nat Rev Cardiol (2010) 2.12
Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases. Free Radic Biol Med (2006) 1.97
Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study. Hypertension (2010) 1.85
Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. Arch Intern Med (2008) 1.68
Resistant hypertension and obstructive sleep apnea in the setting of kidney disease. J Hypertens (2012) 1.49
Endothelial dysfunction in obstructive sleep apnea. J Clin Sleep Med (2007) 1.19
Chronic intermittent hypoxia increases blood pressure and expression of FosB/DeltaFosB in central autonomic regions. Am J Physiol Regul Integr Comp Physiol (2011) 1.07
Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies. Oxid Med Cell Longev (2013) 1.07
Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia. Respir Physiol Neurobiol (2010) 1.07
Altered sympathetic reflexes and vascular reactivity in rats after exposure to chronic intermittent hypoxia. J Physiol (2011) 1.05
Cardiovascular and cerebrovascular responses to acute hypoxia following exposure to intermittent hypoxia in healthy humans. J Physiol (2009) 1.03
Correlation between the severity of obstructive sleep apnea and heart rate variability indices. J Korean Med Sci (2008) 1.01
Neuroendocrine alterations in obese patients with sleep apnea syndrome. Int J Endocrinol (2010) 1.01
Sympathetic and catecholaminergic alterations in sleep apnea with particular emphasis on children. Front Neurol (2012) 0.99
Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia. Am J Physiol Heart Circ Physiol (2008) 0.97
Role of chemoreception in cardiorespiratory acclimatization to, and deacclimatization from, hypoxia. J Appl Physiol (1985) (2013) 0.97
Vascular effects of intermittent hypoxia. ILAR J (2009) 0.96
Mechanisms of intermittent hypoxia induced hypertension. J Cell Mol Med (2009) 0.95
An Essential role for DeltaFosB in the median preoptic nucleus in the sustained hypertensive effects of chronic intermittent hypoxia. Hypertension (2012) 0.95
Pathophysiology of human ventilatory control. Eur Respir J (2014) 0.92
Chronic intermittent hypoxia increases sympathetic control of blood pressure: role of neuronal activity in the hypothalamic paraventricular nucleus. Am J Physiol Heart Circ Physiol (2013) 0.91
Obstructive sleep apnea: the new cardiovascular disease. Part I: Obstructive sleep apnea and the pathogenesis of vascular disease. Heart Fail Rev (2008) 0.90
Chronic intermittent hypoxia-hypercapnia blunts heart rate responses and alters neurotransmission to cardiac vagal neurons. J Physiol (2014) 0.88
Cardiovascular consequences of sleep apnea. Lung (2011) 0.85
OSA: the new cardiovascular disease: part II: Overview of cardiovascular diseases associated with obstructive sleep apnea. Heart Fail Rev (2008) 0.84
Central losartan attenuates increases in arterial pressure and expression of FosB/ΔFosB along the autonomic axis associated with chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol (2013) 0.84
Rab1 GTPase regulates phenotypic modulation of pulmonary artery smooth muscle cells by mediating the transport of angiotensin II type 1 receptor under hypoxia. Int J Biochem Cell Biol (2010) 0.83
Angiotensin II type 1a receptors in subfornical organ contribute towards chronic intermittent hypoxia-associated sustained increase in mean arterial pressure. Am J Physiol Heart Circ Physiol (2014) 0.82
The efficacy of antihypertensive drugs in chronic intermittent hypoxia conditions. Front Physiol (2014) 0.81
Cyclooxygenases 1 and 2 differentially regulate blood pressure and cerebrovascular responses to acute and chronic intermittent hypoxia: implications for sleep apnea. J Am Heart Assoc (2014) 0.81
Low doses of nicotine-induced fetal cardiovascular responses, hypoxia, and brain cellular activation in ovine fetuses. Neurotoxicology (2009) 0.81
Acute intermittent optogenetic stimulation of nucleus tractus solitarius neurons induces sympathetic long-term facilitation. Am J Physiol Regul Integr Comp Physiol (2014) 0.80
Losartan abolishes oxidative stress induced by intermittent hypoxia in humans. J Physiol (2011) 0.80
The implication of protein malnutrition on cardiovascular control systems in rats. Front Physiol (2015) 0.78
Neurogenic mechanisms underlying the rapid onset of sympathetic responses to intermittent hypoxia. J Appl Physiol (1985) (2015) 0.78
Angiotensin II Type 1 Receptors and Systemic Hemodynamic and Renal Responses to Stress and Altered Blood Volume in Conscious Rabbits. Front Physiol (2011) 0.77
Role of angiotensin-converting enzyme 1 within the median preoptic nucleus following chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol (2016) 0.75
Meta-analysis of effects of obstructive sleep apnea on the renin-angiotensin-aldosterone system. J Geriatr Cardiol (2016) 0.75
Intermittent Hypoxia Contributes to the Lung Damage by Increased Oxidative Stress, Inflammation, and Disbalance in Protease/Antiprotease System. Lung (2016) 0.75
Lrp5 functions in bone to regulate bone mass. Nat Med (2011) 5.33
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A (2003) 5.08
Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science (2003) 4.58
Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med (2008) 3.10
Platelet-derived serotonin mediates liver regeneration. Science (2006) 2.98
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel. Circ Res (2006) 2.67
Weight loss and the renin-angiotensin-aldosterone system. Hypertension (2005) 2.58
Serotonin regulates mammary gland development via an autocrine-paracrine loop. Dev Cell (2004) 2.40
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. PLoS Biol (2009) 2.40
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell (2003) 2.28
A unique central tryptophan hydroxylase isoform. Biochem Pharmacol (2003) 2.23
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning. Nat Med (2002) 2.20
Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol (2011) 2.04
Using Google Earth to conduct a neighborhood audit: reliability of a virtual audit instrument. Health Place (2010) 2.03
Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci U S A (2009) 2.01
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema. Stroke (2008) 1.90
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension (2008) 1.81
Axonal transcription factors signal retrogradely in lesioned peripheral nerve. EMBO J (2012) 1.77
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci (2007) 1.74
Serotonin is required for exercise-induced adult hippocampal neurogenesis. J Neurosci (2013) 1.72
Mobility disability and the urban built environment. Am J Epidemiol (2008) 1.72
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex. Development (2010) 1.68
Transgenic rat model of Huntington's disease. Hum Mol Genet (2003) 1.66
Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron. J Biol Chem (2010) 1.65
Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus. Nat Commun (2011) 1.65
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors. Anal Chem (2004) 1.63
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene. J Biol Chem (2003) 1.60
Leptin regulates ACE activity in mice. J Mol Med (Berl) (2010) 1.59
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ Res (2008) 1.59
Determination of mercury in blood, urine and saliva for the biological monitoring of an exposure from amalgam fillings in a group with self-reported adverse health effects. Int J Hyg Environ Health (2002) 1.55
Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis. J Mol Med (Berl) (2002) 1.54
Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism. Diabetes (2007) 1.52
Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension (2006) 1.51
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension (2010) 1.50
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension (2008) 1.48
Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system. J Endocrinol (2013) 1.48
Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B(1) receptors. J Mol Med (Berl) (2008) 1.47
Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells. Cell Res (2009) 1.46
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E. J Mol Med (Berl) (2009) 1.45
Reconsidering access: park facilities and neighborhood disamenities in New York City. J Urban Health (2011) 1.44
Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin. J Hypertens (2013) 1.44
Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload. PLoS One (2009) 1.43
Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42
SDF-1α as a therapeutic stem cell homing factor in myocardial infarction. Pharmacol Ther (2010) 1.42
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. Hypertension (2005) 1.39
Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice. Hypertension (2008) 1.37
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens (2007) 1.35
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation (2006) 1.33
Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice. Am J Physiol Renal Physiol (2004) 1.32
Isolation of Oct4-expressing extraembryonic endoderm precursor cell lines. PLoS One (2009) 1.29
Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation. J Cereb Blood Flow Metab (2010) 1.28
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. Nat Med (2009) 1.27
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria. Kidney Int (2009) 1.27
Early prediction of response to chemotherapy in metastatic breast cancer using sequential 18F-FDG PET. J Nucl Med (2005) 1.27
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats. Physiol Genomics (2004) 1.25
Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension (2006) 1.24
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes. Hypertension (2008) 1.19
Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B. Proc Natl Acad Sci U S A (2006) 1.18
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy. J Biol Chem (2008) 1.17
Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury. J Immunol (2004) 1.17
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS One (2009) 1.15
Detrimental implication of B1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice. Int Immunopharmacol (2002) 1.15
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation. Hum Mutat (2007) 1.14
Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, MAS, in experimental models of arthritis. J Immunol (2010) 1.14
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation (2008) 1.13
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system. Circ Res (2013) 1.13
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts. Cancer Res (2008) 1.12
Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney. Hypertension (2004) 1.12
Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction. Hypertension (2008) 1.12
Role of the B1 kinin receptor in the regulation of cardiac function and remodeling after myocardial infarction. Hypertension (2005) 1.12
Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension. Hypertension (2006) 1.12
Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis. Gastroenterology (2007) 1.11
Transgenic activation of the kallikrein-kinin system inhibits intramyocardial inflammation, endothelial dysfunction and oxidative stress in experimental diabetic cardiomyopathy. FASEB J (2005) 1.11
Mass-spectrometric identification of a novel angiotensin peptide in human plasma. Arterioscler Thromb Vasc Biol (2006) 1.10
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice. Blood (2012) 1.09
Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation. Cardiovasc Res (2006) 1.09
Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy. Diabetes (2009) 1.09
Targeting kinin B(1) receptor for therapeutic neovascularization. Circulation (2002) 1.08
Mice deficient for both kinin receptors are normotensive and protected from endotoxin-induced hypotension. FASEB J (2007) 1.08
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice. Hepatology (2007) 1.08
Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system. Pharmacol Rep (2009) 1.08
ACE2-angiotensin-(1-7)-Mas axis and oxidative stress in cardiovascular disease. Hypertens Res (2010) 1.08
Specification and differentiation of serotonergic neurons. Stem Cell Rev (2006) 1.08
Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene. FASEB J (2004) 1.08
Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice. Circulation (2008) 1.08
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J (2012) 1.07
Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor (B1/B2) subtypes. FASEB J (2002) 1.06
Physiology of the (pro)renin receptor: Wnt of change? Kidney Int (2010) 1.05
Animal models for hypertension/blood pressure recording. Methods Mol Med (2006) 1.04
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7). Arterioscler Thromb Vasc Biol (2010) 1.04
Induction and analysis of cardiac hypertrophy in transgenic animal models. Methods Mol Med (2005) 1.04
Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling. Hum Mol Genet (2013) 1.03
Genetically altered animal models for Mas and angiotensin-(1-7). Exp Physiol (2007) 1.03
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium. J Clin Endocrinol Metab (2014) 1.02
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension. J Hypertens (2009) 1.02
Rat corin gene: molecular cloning and reduced expression in experimental heart failure. Am J Physiol Heart Circ Physiol (2004) 1.02
Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2008) 1.01
In vivo bradykinin B2 receptor activation reduces renal fibrosis. J Clin Invest (2002) 1.01
Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth. Int J Cancer (2005) 1.01
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene. J Am Soc Nephrol (2002) 1.01