Published in FASEB J on November 01, 2002
Pathogenesis of chagas' disease: parasite persistence and autoimmunity. Clin Microbiol Rev (2011) 1.38
Chagas heart disease pathogenesis: one mechanism or many? Curr Mol Med (2008) 1.26
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. J Clin Invest (2006) 1.24
Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis (2011) 1.17
Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol (2004) 1.17
Molecular mechanisms of host cell invasion by Trypanosoma cruzi. Exp Parasitol (2010) 1.04
All Trypanosoma cruzi developmental forms present lysosome-related organelles. Histochem Cell Biol (2008) 1.03
Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy. Br J Pharmacol (2012) 0.99
A new cruzipain-mediated pathway of human cell invasion by Trypanosoma cruzi requires trypomastigote membranes. Infect Immun (2004) 0.97
Perspectives on the Trypanosoma cruzi-host cell receptor interactions. Parasitol Res (2009) 0.92
Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead. Am J Pathol (2015) 0.90
Current understanding of the Trypanosoma cruzi-cardiomyocyte interaction. Front Immunol (2012) 0.88
Captopril increases the intensity of monocyte infection by Trypanosoma cruzi and induces human T helper type 17 cells. Clin Exp Immunol (2010) 0.87
The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosoma cruzi. Front Immunol (2013) 0.86
Molecular analysis of early host cell infection by Trypanosoma cruzi. Front Biosci (2008) 0.85
Trypanosoma cruzi highjacks TrkC to enter cardiomyocytes and cardiac fibroblasts while exploiting TrkA for cardioprotection against oxidative stress. Cell Microbiol (2013) 0.79
Endothelin and bradykinin: 'brothers-in-arms' in Chagas vasculopathies? Br J Pharmacol (2012) 0.76
Endothelial transmigration by Trypanosoma cruzi. PLoS One (2013) 0.76
Differential Expression of Inflammation-Related Genes in Children with Down Syndrome. Mediators Inflamm (2016) 0.75
Mammalian cellular culture models of Trypanosoma cruzi infection: a review of the published literature. Parasite (2014) 0.75
Mechanisms of Infectivity and Evasion Derived from Microvesicles Cargo Produced by Trypanosoma cruzi. Front Cell Infect Microbiol (2016) 0.75
Characterization of the M32 metallocarboxypeptidase of Trypanosoma brucei: differences and similarities with its orthologue in Trypanosoma cruzi. Mol Biochem Parasitol (2012) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Lrp5 functions in bone to regulate bone mass. Nat Med (2011) 5.33
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A (2003) 5.08
Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science (2003) 4.58
A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder. Am J Psychiatry (2002) 4.09
Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med (2008) 3.10
International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev (2005) 2.98
Platelet-derived serotonin mediates liver regeneration. Science (2006) 2.98
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel. Circ Res (2006) 2.67
Weight loss and the renin-angiotensin-aldosterone system. Hypertension (2005) 2.58
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels. J Clin Invest (2006) 2.52
Serotonin regulates mammary gland development via an autocrine-paracrine loop. Dev Cell (2004) 2.40
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. PLoS Biol (2009) 2.40
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell (2003) 2.28
A unique central tryptophan hydroxylase isoform. Biochem Pharmacol (2003) 2.23
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning. Nat Med (2002) 2.20
EGFR and KRAS mutations in lung carcinoma: molecular testing by using cytology specimens. Cancer Cytopathol (2011) 2.19
Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol (2011) 2.04
Using Google Earth to conduct a neighborhood audit: reliability of a virtual audit instrument. Health Place (2010) 2.03
Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci U S A (2009) 2.01
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema. Stroke (2008) 1.90
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension (2008) 1.81
Axonal transcription factors signal retrogradely in lesioned peripheral nerve. EMBO J (2012) 1.77
Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling. J Exp Med (2003) 1.74
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci (2007) 1.74
Serotonin is required for exercise-induced adult hippocampal neurogenesis. J Neurosci (2013) 1.72
Mobility disability and the urban built environment. Am J Epidemiol (2008) 1.72
Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells. Circ Res (2003) 1.69
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex. Development (2010) 1.68
Transgenic rat model of Huntington's disease. Hum Mol Genet (2003) 1.66
Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron. J Biol Chem (2010) 1.65
Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus. Nat Commun (2011) 1.65
Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2. J Med Microbiol (2004) 1.63
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors. Anal Chem (2004) 1.63
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene. J Biol Chem (2003) 1.60
Autopoiesis and cognition. Artif Life (2004) 1.59
Leptin regulates ACE activity in mice. J Mol Med (Berl) (2010) 1.59
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ Res (2008) 1.59
Determination of mercury in blood, urine and saliva for the biological monitoring of an exposure from amalgam fillings in a group with self-reported adverse health effects. Int J Hyg Environ Health (2002) 1.55
Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells. J Cell Sci (2005) 1.55
Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis. J Mol Med (Berl) (2002) 1.54
Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism. Diabetes (2007) 1.52
Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension (2006) 1.51
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension (2010) 1.50
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension (2008) 1.48
Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system. J Endocrinol (2013) 1.48
Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B(1) receptors. J Mol Med (Berl) (2008) 1.47
Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells. Cell Res (2009) 1.46
Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity (2011) 1.46
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E. J Mol Med (Berl) (2009) 1.45
The feasibility of gene expression profiling generated in fine-needle aspiration specimens from patients with follicular lymphoma and diffuse large B-cell lymphoma. Cancer (2006) 1.45
Reconsidering access: park facilities and neighborhood disamenities in New York City. J Urban Health (2011) 1.44
Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin. J Hypertens (2013) 1.44
Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload. PLoS One (2009) 1.43
Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42
SDF-1α as a therapeutic stem cell homing factor in myocardial infarction. Pharmacol Ther (2010) 1.42
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. Hypertension (2005) 1.39
Subcellular targeting and trafficking of nitric oxide synthases. Biochem J (2006) 1.37
Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice. Hypertension (2008) 1.37
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens (2007) 1.35
Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system. J Appl Physiol (1985) (2002) 1.35
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation (2006) 1.33
Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice. Am J Physiol Renal Physiol (2004) 1.32
Ten year longitudinal study of neuropsychological functioning subsequent to a first episode of schizophrenia. Schizophr Res (2005) 1.32
Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension. Circ Res (2011) 1.31
Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal. Nat Cell Biol (2009) 1.29
Isolation of Oct4-expressing extraembryonic endoderm precursor cell lines. PLoS One (2009) 1.29
Nitric oxide-independent vasodilator rescues heme-oxidized soluble guanylate cyclase from proteasomal degradation. Circ Res (2009) 1.29
Safety of autologous bone marrow mononuclear cell transplantation in patients with nonacute ischemic stroke. Regen Med (2011) 1.28
Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation. J Cereb Blood Flow Metab (2010) 1.28
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. Nat Med (2009) 1.27
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria. Kidney Int (2009) 1.27
Early prediction of response to chemotherapy in metastatic breast cancer using sequential 18F-FDG PET. J Nucl Med (2005) 1.27
Ecological change, range fluctuations and population dynamics during the Pleistocene. Curr Biol (2009) 1.26
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats. Physiol Genomics (2004) 1.25
Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplants is the complex result of BK virus infection, preparative regimen intensity and donor type. Haematologica (2010) 1.25
The Diabetes Treatment Satisfaction Questionnaire change version (DTSQc) evaluated in insulin glargine trials shows greater responsiveness to improvements than the original DTSQ. Health Qual Life Outcomes (2007) 1.24
Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension (2006) 1.24
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. J Clin Invest (2006) 1.24
Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo. Thromb Haemost (2004) 1.23
Bone marrow multipotent mesenchymal stromal cells do not reduce fibrosis or improve function in a rat model of severe chronic liver injury. Stem Cells (2008) 1.21
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes. Hypertension (2008) 1.19
Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B. Proc Natl Acad Sci U S A (2006) 1.18
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy. J Biol Chem (2008) 1.17
Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury. J Immunol (2004) 1.17
Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest (2010) 1.17
Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings. Am J Clin Pathol (2006) 1.16
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS One (2009) 1.15
Detrimental implication of B1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice. Int Immunopharmacol (2002) 1.15
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation. Hum Mutat (2007) 1.14
Local bradykinin formation is controlled by glycosaminoglycans. J Immunol (2005) 1.14
Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, MAS, in experimental models of arthritis. J Immunol (2010) 1.14
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice. Circulation (2008) 1.13
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system. Circ Res (2013) 1.13