John K Sheehan

Author PubWeight™ 32.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science 2012 2.98
2 Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J 2009 2.07
3 Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B. Biochem J 2002 2.02
4 From mucins to mucus: toward a more coherent understanding of this essential barrier. Proc Am Thorac Soc 2004 2.02
5 Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol 2008 1.55
6 Unpacking a gel-forming mucin: a view of MUC5B organization after granular release. Am J Physiol Lung Cell Mol Physiol 2009 1.52
7 Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces. J Immunol 2005 1.38
8 Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways. J Physiol 2008 1.33
9 Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest 2014 1.26
10 Mucins and their O-Glycans from human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol 2004 1.20
11 Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. J Immunol 2009 1.17
12 Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus. J Biol Chem 2003 1.14
13 Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans. J Biol Chem 2006 1.12
14 The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. J Biol Chem 2005 1.06
15 Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva. Biochem J 2002 0.99
16 The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Sci Rep 2012 0.98
17 Light and X-ray scattering show decorin to be a dimer in solution. J Biol Chem 2003 0.97
18 Predicting the molecular shape of polysaccharides from dynamic interactions with water. Glycobiology 2002 0.93
19 Mapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study. J Proteome Res 2012 0.90
20 Analyzing the functions of large glycoconjugates through the dissipative properties of their absorbed layers using the gel-forming mucin MUC5B as an example. Glycobiology 2008 0.90
21 Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide. J Mol Microbiol Biotechnol 2009 0.90
22 Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol 2009 0.88
23 Mass spectrometric analysis of mucin core proteins. Methods Mol Biol 2012 0.87
24 Making More MUCS. Am J Respir Cell Mol Biol 2003 0.85
25 Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures. Am J Physiol Lung Cell Mol Physiol 2011 0.85
26 Studying mucin secretion from human bronchial epithelial cell primary cultures. Methods Mol Biol 2012 0.84
27 Partial characterisation of high-molecular weight glycoconjugates in the trail mucus of the freshwater pond snail Lymnaea stagnalis. Comp Biochem Physiol B Biochem Mol Biol 2004 0.82
28 Interaction of mucus with freshly neutralised aluminium in freshwater. J Inorg Biochem 2002 0.75