Published in J Bioenerg Biomembr on December 01, 2001
Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays. Nucleic Acids Res (2003) 1.16
The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis. Antimicrob Agents Chemother (2003) 1.13
Glibenclamide, a blocker of K+(ATP) channels, shows antileishmanial activity in experimental murine cutaneous leishmaniasis. Antimicrob Agents Chemother (2006) 1.00
Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania. Antimicrob Agents Chemother (2011) 0.87
Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovani. Parasitol Res (2014) 0.86
Antimony resistance during Visceral Leishmaniasis: A possible consequence of serial mutations in ABC transporters of Leishmania species. Bioinformation (2011) 0.76
P-glycoprotein A Gene Expression in Glucantime-Resistant and Sensitive Leishmania major (MRHO/IR/75/ER). Iran J Parasitol (2014) 0.75
The complete genome sequence of Escherichia coli K-12. Science (1997) 84.27
ABC transporters: from microorganisms to man. Annu Rev Cell Biol (1992) 19.49
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (1992) 8.84
Leishmaniasis. Lancet (1999) 7.20
Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years. Clin Infect Dis (1997) 4.23
The Escherichia coli ATP-binding cassette (ABC) proteins. Mol Microbiol (1998) 3.77
Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol (1992) 3.57
The ATP-dependent glutathione S-conjugate export pump. Trends Biochem Sci (1992) 3.22
Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J Infect Dis (1999) 2.92
Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. J Mol Evol (1999) 2.78
The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem (1996) 2.75
Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein. J Biol Chem (1995) 2.64
Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes. Proc Natl Acad Sci U S A (1999) 2.37
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems. J Mol Biol (1999) 2.29
An inventory of the human ABC proteins. Biochim Biophys Acta (1999) 2.22
Complete inventory of the yeast ABC proteins. Nat Genet (1997) 2.22
Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1999) 2.02
Drug resistance in leishmaniasis: its implication in systemic chemotherapy of cutaneous and mucocutaneous disease. Am J Trop Med Hyg (1992) 1.83
Short-course, low-dose amphotericin B lipid complex therapy for visceral leishmaniasis unresponsive to antimony. Ann Intern Med (1997) 1.80
The multidrug resistance protein family. Biochim Biophys Acta (1999) 1.79
The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1. Proc Natl Acad Sci U S A (1996) 1.78
The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene. EMBO J (1990) 1.74
Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proc Natl Acad Sci U S A (1996) 1.74
A comparative analysis of ABC transporters in complete microbial genomes. Genome Res (1998) 1.73
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res (1999) 1.72
The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death. EMBO J (1996) 1.69
In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis. Antimicrob Agents Chemother (1997) 1.67
Heavy metal resistance: a new role for P-glycoproteins in Leishmania. J Biol Chem (1991) 1.55
Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO J (1997) 1.49
The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase. J Biol Chem (2001) 1.48
An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae. Proc Natl Acad Sci U S A (1996) 1.44
Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim Biophys Acta (1999) 1.42
Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania. Mol Microbiol (1999) 1.40
Quantitative in vitro drug potency and drug susceptibility evaluation of Leishmania ssp. from patients unresponsive to pentavalent antimony therapy. Am J Trop Med Hyg (1990) 1.37
High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system. Mol Biochem Parasitol (1994) 1.31
The GS-X pump in plant, yeast, and animal cells: structure, function, and gene expression. Biosci Rep (1997) 1.29
Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene. Mol Cell Biol (1992) 1.27
Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol Biochem Parasitol (2000) 1.24
Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania. Exp Parasitol (1997) 1.20
Saccharomyces cerevisiae ABC proteins and their relevance to human health and disease. Methods Enzymol (1998) 1.11
Leishmania resistant to sodium stibogluconate: drug-associated macrophage-dependent killing. Parasitol Res (1994) 1.09
Contribution of the Leishmania P-glycoprotein-related gene ltpgpA to oxyanion resistance. J Biol Chem (1994) 1.07
Correlation between the affinity of flavonoids binding to the cytosolic site of Leishmania tropica multidrug transporter and their efficiency to revert parasite resistance to daunomycin. Biochemistry (1999) 1.03
Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line. Biochem Pharmacol (1998) 1.02
The ABCA subclass of mammalian transporters. Biochim Biophys Acta (1999) 0.97
ABC transporters in Leishmania and their role in drug resistance. Drug Resist Updat (1998) 0.97
The P-glycoprotein-related gene family in Leishmania. Mol Biochem Parasitol (1994) 0.94
Leishmania amazonensis: multidrug resistance in vinblastine-resistant promastigotes is associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene. Exp Parasitol (1995) 0.93
P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica. Biochem Pharmacol (1994) 0.93
Cloning and functional analysis of an extrachromosomally amplified multidrug resistance-like gene in Leishmania enriettii. Mol Biochem Parasitol (1993) 0.92
Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption. Methods Enzymol (1998) 0.89
Structural and functional analysis of the LaMDR1 multidrug resistance gene in Leishmania amazonensis. Biochem Biophys Res Commun (1999) 0.85
Plasmodium and Leishmania: the role of mdr genes in mediating drug resistance. Exp Parasitol (1998) 0.79
Extension of life-span by introduction of telomerase into normal human cells. Science (1998) 20.48
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat Genet (1997) 6.69
New real-time PCR assay for rapid detection of methicillin-resistant Staphylococcus aureus directly from specimens containing a mixture of staphylococci. J Clin Microbiol (2004) 6.06
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet (2000) 5.42
Species-specific and ubiquitous-DNA-based assays for rapid identification of Staphylococcus aureus. J Clin Microbiol (1998) 4.51
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat Genet (1999) 4.22
Correlation between the resistance genotype determined by multiplex PCR assays and the antibiotic susceptibility patterns of Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob Agents Chemother (2000) 3.26
Rapid detection of group B streptococci in pregnant women at delivery. N Engl J Med (2000) 3.19
Functional requirement of p23 and Hsp90 in telomerase complexes. Genes Dev (1999) 3.19
Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei. Nature (1990) 2.91
Development of conventional and real-time PCR assays for the rapid detection of group B streptococci. Clin Chem (2000) 2.86
Prevalence of coronary heart disease and risk factors in an urban Indian population: Jaipur Heart Watch-2. Indian Heart J (2002) 2.79
The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. EMBO J (1990) 2.41
Pharmacology of CFTR chloride channel activity. Physiol Rev (1999) 2.41
Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus: a preliminary report. Minim Invasive Neurosurg (2005) 2.29
Uremic pruritus. Kidney Int (2007) 2.28
T1-weighted dynamic contrast-enhanced MR evaluation of different stages of neurocysticercosis and its relationship with serum MMP-9 expression. AJNR Am J Neuroradiol (2012) 2.23
Fourier transform infrared difference spectroscopy of bacteriorhodopsin and its photoproducts. Proc Natl Acad Sci U S A (1982) 2.18
Development of a PCR assay for identification of staphylococci at genus and species levels. J Clin Microbiol (2001) 2.17
The axes of rotation of the knee. Clin Orthop Relat Res (1993) 2.10
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models. Mol Biochem Parasitol (2000) 2.10
Development of a PCR assay for rapid detection of enterococci. J Clin Microbiol (1999) 2.09
Intraoperative use of end-tidal carbon dioxide tension to assess cardiac output. J Thorac Cardiovasc Surg (1994) 2.05
Acute renal failure in Plasmodium vivax malaria. J Assoc Physicians India (2003) 2.02
Cell turnover in the rat small intestinal mucosa: an appraisal of cell loss. II. Cell loss in rats with an abnormal mucosa. Gut (1969) 2.00
Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro. Mol Cell Biol (1999) 1.96
Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia. Br J Cancer (2008) 1.93
Characterization of the antigen (gp600) of Heymann nephritis. Lab Invest (1984) 1.88
Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells. J Gen Physiol (1999) 1.88
Hypertension in pregnancy: hospital based study. J Assoc Physicians India (2006) 1.87
Occurrence of the Campylobacter resistance gene tetO in Enterococcus and Streptococcus spp. Antimicrob Agents Chemother (1988) 1.83
A novel antifolate resistance gene on the amplified H circle of Leishmania. EMBO J (1992) 1.82
Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel. Am J Physiol (1996) 1.78
New mechanisms of drug resistance in parasitic protozoa. Annu Rev Microbiol (1995) 1.77
Preventing antibiotic resistance through rapid genotypic identification of bacteria and of their antibiotic resistance genes in the clinical microbiology laboratory. J Clin Microbiol (1998) 1.77
Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proc Natl Acad Sci U S A (1996) 1.74
Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease. J Pharmacol Exp Ther (2001) 1.74
Species-specific and ubiquitous DNA-based assays for rapid identification of Staphylococcus epidermidis. J Clin Microbiol (1996) 1.70
Relaxin decreases renal interstitial fibrosis and slows progression of renal disease. Kidney Int (2001) 1.70
Bis-benzimidazole anticancer agents: targeting human tumour helicases. Anticancer Drug Des (1999) 1.66
Pursuing scale and quality in STI interventions with sex workers: initial results from Avahan India AIDS Initiative. Sex Transm Infect (2006) 1.62
Multiplex PCR assays for the detection of clinically relevant antibiotic resistance genes in staphylococci isolated from patients infected after cardiac surgery. The ESPRIT Trial. J Antimicrob Chemother (2000) 1.58
Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages. EMBO J (1997) 1.58
Mechanisms of drug resistance in Leishmania. Parasitol Today (1993) 1.58
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages. J Cell Sci (2000) 1.55
PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions. Mucosal Immunol (2009) 1.53
Volatile Constituents of Artemisia nilagirica. Planta Med (1985) 1.53
Glucantime-resistant Leishmania tropica isolated from Iranian patients with cutaneous leishmaniasis are sensitive to alternative antileishmania drugs. Parasitol Res (2007) 1.52
B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months. Am J Transplant (2011) 1.51
Plasmid-mediated resistance to multiple antibiotics in Salmonella typhi. J Infect Dis (1986) 1.50
Nineteen-millimeter aortic St. Jude Medical heart valve prosthesis: up to sixteen years' follow-up. Ann Thorac Surg (1997) 1.50
Visual evoked potentials and visual acuity after transurethral resection of the prostate. Anaesthesia (1991) 1.49
Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO J (1997) 1.49
The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase. J Biol Chem (2001) 1.48
Slc26a3 deficiency is associated with loss of colonic HCO3 (-) secretion, absence of a firm mucus layer and barrier impairment in mice. Acta Physiol (Oxf) (2014) 1.48
EPODE approach for childhood obesity prevention: methods, progress and international development. Obes Rev (2011) 1.47
Global analysis of heat shock response in Desulfovibrio vulgaris Hildenborough. J Bacteriol (2006) 1.46
Acceleration of viral replication and up-regulation of cytokine levels by antimalarials: implications in malaria-endemic areas. Am J Trop Med Hyg (1999) 1.45
An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae. Proc Natl Acad Sci U S A (1996) 1.44
Antifungal Activity of Nor-securinine Against Some Phytopathogenic Fungi. Mycobiology (2005) 1.42
Dynamics of organic carbon and microbial biomass in alluvial soil with tillage and amendments in rice-wheat systems. Environ Monit Assess (2006) 1.42
Evidence for horizontal gene transfer in evolution of elongation factor Tu in enterococci. J Bacteriol (2000) 1.42
Accepting prospective kidney donors with asymptomatic urinary abnormalities: are we shooting in the dark? Kidney Int (2006) 1.40
The role of gandhka jarana in the preparation of samguna and sadaguna rasa sindura. Anc Sci Life (1994) 1.40
Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania. Mol Microbiol (1999) 1.40
Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic mice. Wound Repair Regen (1999) 1.40
DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening. Antimicrob Agents Chemother (2001) 1.39
Right ventricular function after normothermic versus hypothermic cardiopulmonary bypass. J Thorac Cardiovasc Surg (1993) 1.39
An in-vitro direct chemiluminescence assay for assessment of platelet-bound antibody in thrombocytopenic patients. Br J Haematol (1991) 1.39
Postblock epidural hematoma causing paraplegia. Case report. Reg Anesth (1994) 1.39
Role of angiotensin II in diabetic nephropathy. Kidney Int Suppl (2000) 1.38
Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. J Neurosci Res (2001) 1.37
Saliva/pathogen biomarker signatures and periodontal disease progression. J Dent Res (2011) 1.37
Crossed fused ectopia of the kidneys. Kidney Int (2008) 1.36
Enhancement of wound healing by curcumin in animals. Wound Repair Regen (1999) 1.34
Prominent and sustained up-regulation of gp130-signaling cytokines and the chemokine MIP-2 in murine renal ischemia-reperfusion injury. Transplantation (2000) 1.33
Osmoreceptors, osmoreception, and osmoregulation. Front Neuroendocrinol (1994) 1.32
High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system. Mol Biochem Parasitol (1994) 1.31
False-positive Western blot reactions to human immunodeficiency virus in blood donors. Lancet (1986) 1.31
Analysis by using DNA probes of the OXA-1 beta-lactamase gene and its transposon. Antimicrob Agents Chemother (1986) 1.30
Glibenclamide blockade of CFTR chloride channels. Am J Physiol (1996) 1.30
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. J Biol Chem (1998) 1.29
Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels. Am J Physiol Cell Physiol (2000) 1.29
The changing pattern of trimethoprim resistance in Paris, with a review of worldwide experience. Rev Infect Dis (1986) 1.29
Autonomous replication of bacterial DNA plasmid oligomers in Leishmania. Mol Biochem Parasitol (1994) 1.28
Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania. Nucleic Acids Res (1993) 1.28
Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus. Proc Natl Acad Sci U S A (2001) 1.28
Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice. Pflugers Arch (2008) 1.26
Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae. Mol Biochem Parasitol (2000) 1.24
Treatment of the alcohol intoxications: ethylene glycol, methanol and isopropanol. Curr Opin Nephrol Hypertens (2000) 1.23