Published in Antimicrob Agents Chemother on December 01, 1988
Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance. Clin Microbiol Rev (1992) 3.51
In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclines. Antimicrob Agents Chemother (1993) 3.13
A Bacteroides tetracycline resistance gene represents a new class of ribosome protection tetracycline resistance. Antimicrob Agents Chemother (1992) 2.11
Transfer of antibiotic resistance genes between gram-positive and gram-negative bacteria. Antimicrob Agents Chemother (1994) 1.85
Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains of Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. Antimicrob Agents Chemother (2003) 1.82
Plasmid-mediated 4-quinolone resistance: a real or apparent absence? Antimicrob Agents Chemother (1990) 1.75
Gene heterogeneity for tetracycline resistance in Staphylococcus spp. Antimicrob Agents Chemother (1990) 1.60
Isolation of tetracycline-resistant Megasphaera elsdenii strains with novel mosaic gene combinations of tet(O) and tet(W) from swine. Appl Environ Microbiol (2003) 1.58
Gene homogeneity for aminoglycoside-modifying enzymes in gram-positive cocci. Antimicrob Agents Chemother (1990) 1.56
Genetic basis of tetracycline resistance in urogenital bacteria. Antimicrob Agents Chemother (1990) 1.48
Expression of the strA-strB streptomycin resistance genes in Pseudomonas syringae and Xanthomonas campestris and characterization of IS6100 in X. campestris. Appl Environ Microbiol (1995) 1.45
Genetic basis of tetracycline resistance in clinical isolates of Listeria monocytogenes. Antimicrob Agents Chemother (1992) 1.41
Characterization of the Tet M determinants in urogenital and respiratory bacteria. Antimicrob Agents Chemother (1990) 1.28
Presence of the Listeria tetracycline resistance gene tet(S) in Enterococcus faecalis. Antimicrob Agents Chemother (1994) 1.20
Identification of the tetracycline resistance gene, tet(O), in Streptococcus pneumoniae. Antimicrob Agents Chemother (1996) 1.16
Tetracycline resistance in Peptostreptococcus species. Antimicrob Agents Chemother (1991) 0.95
Nucleotide sequences specific for Tn1545-like conjugative transposons in pneumococci and staphylococci resistant to tetracycline. Antimicrob Agents Chemother (1991) 0.95
Genetic basis of tetracycline resistance in food-borne isolates of Listeria innocua. Appl Environ Microbiol (1993) 0.94
Six-month multicenter study on invasive infections due to group B streptococci in Argentina. J Clin Microbiol (2003) 0.94
Effects of orally administered tetracycline on the intestinal community structure of chickens and on tet determinant carriage by commensal bacteria and Campylobacter jejuni. Appl Environ Microbiol (2005) 0.93
Mechanisms of action of systemic antibiotics used in periodontal treatment and mechanisms of bacterial resistance to these drugs. J Appl Oral Sci (2012) 0.92
Molecular diversity and characterization of tetracycline-resistant Staphylococcus aureus isolates from a poultry processing plant. Appl Environ Microbiol (2005) 0.89
Emergence of aminoglycoside resistance genes aadA and aadE in the genus Campylobacter. Antimicrob Agents Chemother (1990) 0.85
Characterization of unusual tetracycline-resistant gram-positive bacteria. Antimicrob Agents Chemother (1991) 0.82
Host mutations (miaA and rpsL) reduce tetracycline resistance mediated by Tet(O) and Tet(M). Antimicrob Agents Chemother (1998) 0.79
A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res (1979) 214.95
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene (1982) 102.30
The making of strand-specific M13 probes. Gene (1982) 14.60
High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant. Antimicrob Agents Chemother (1986) 6.34
Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol (1982) 6.20
Complete nucleotide sequence of pT181, a tetracycline-resistance plasmid from Staphylococcus aureus. Plasmid (1983) 4.52
Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol Gen Genet (1986) 4.49
Nucleotide sequence of the tetM tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545. Nucleic Acids Res (1986) 4.47
In vivo transfer of genetic information between gram-positive and gram-negative bacteria. EMBO J (1985) 4.24
Tetracycline-resistant Mycoplasma hominis strains contain streptococcal tetM sequences. Antimicrob Agents Chemother (1985) 3.66
Plasmid-mediated resistance to aminocyclitol antibiotics in group D streptococci. J Bacteriol (1980) 3.55
Identification and analysis of genes for tetracycline resistance and replication functions in the broad-host-range plasmid pLS1. J Mol Biol (1986) 3.47
Streptococcal tetracycline resistance mediated at the level of protein synthesis. J Bacteriol (1986) 3.46
Evidence for natural gene transfer from gram-positive cocci to Escherichia coli. J Bacteriol (1988) 3.43
Identification of tetracycline-resistant R-plasmids in Streptococcus agalactiae (group B). Antimicrob Agents Chemother (1980) 3.40
Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum. Antimicrob Agents Chemother (1986) 3.08
Structural relationship between the genes encoding 3'-aminoglycoside phosphotransferases in Campylobacter and in gram-positive cocci. Ann Inst Pasteur Microbiol (1986) 2.92
Characterization of tetracycline resistance plasmids from Campylobacter jejuni and Campylobacter coli. Antimicrob Agents Chemother (1983) 2.40
Tetracycline resistance and tetM in pathogenic urogenital bacteria. Antimicrob Agents Chemother (1986) 2.01
Nucleotide sequence of the tetracycline resistance gene of pTHT15, a thermophilic Bacillus plasmid: comparison with staphylococcal TcR controls. Gene (1985) 1.95
A new tetracycline-resistance determinant, class E, isolated from Enterobacteriaceae. Gene (1986) 1.95
Streptococcus plasmid pAM alpha 1 is a composite of two separable replicons, one of which is closely related to Bacillus plasmid pBC16. J Bacteriol (1983) 1.81
Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci. Antimicrob Agents Chemother (1987) 1.72
Phenotypic expression and genetic heterogeneity of lincosamide inactivation in Staphylococcus spp. Antimicrob Agents Chemother (1987) 1.53
Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N Engl J Med (1988) 16.74
Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J Clin Microbiol (1995) 12.98
Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type III. Gene (1983) 8.32
Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants. Antimicrob Agents Chemother (1999) 7.94
Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification. Antimicrob Agents Chemother (1991) 7.18
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J Bacteriol (1993) 6.96
Genetics and mechanisms of glycopeptide resistance in enterococci. Antimicrob Agents Chemother (1993) 6.28
Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta-lactamase. J Antimicrob Chemother (1987) 6.27
Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry (1991) 5.90
Transferable vancomycin and teicoplanin resistance in Enterococcus faecium. Antimicrob Agents Chemother (1989) 5.31
Multidrug resistance in Yersinia pestis mediated by a transferable plasmid. N Engl J Med (1997) 5.23
The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J Bacteriol (1992) 4.99
Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol Gen Genet (1986) 4.49
Nucleotide sequence of the tetM tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545. Nucleic Acids Res (1986) 4.47
Development of "oligotyping" for characterization and molecular epidemiology of TEM beta-lactamases in members of the family Enterobacteriaceae. Antimicrob Agents Chemother (1990) 4.45
In vivo transfer of genetic information between gram-positive and gram-negative bacteria. EMBO J (1985) 4.24
Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro. Antimicrob Agents Chemother (1996) 3.95
Identification of vancomycin resistance protein VanA as a D-alanine:D-alanine ligase of altered substrate specificity. Biochemistry (1991) 3.76
Nucleotide sequence of the erythromycin resistance gene of the conjugative transposon Tn1545. Nucleic Acids Res (1990) 3.74
Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine:D-alanine ligase-related protein necessary for vancomycin resistance. Gene (1992) 3.68
The VANA glycopeptide resistance protein is related to D-alanyl-D-alanine ligase cell wall biosynthesis enzymes. Mol Gen Genet (1990) 3.66
Vancomycin resistance gene vanC is specific to Enterococcus gallinarum. Antimicrob Agents Chemother (1992) 3.63
Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454. Antimicrob Agents Chemother (2001) 3.56
Plasmid-mediated resistance to aminocyclitol antibiotics in group D streptococci. J Bacteriol (1980) 3.55
Characterization of a mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (1997) 3.50
Plasmid-mediated resistance to third-generation cephalosporins caused by point mutations in TEM-type penicillinase genes. Rev Infect Dis (1988) 3.49
Evidence for natural gene transfer from gram-positive cocci to Escherichia coli. J Bacteriol (1988) 3.43
Glycopeptide resistance in enterococci. Trends Microbiol (1996) 3.42
Phenotypic and genotypic heterogeneity of glycopeptide resistance determinants in gram-positive bacteria. Antimicrob Agents Chemother (1990) 3.33
Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: homologies with other site-specific recombinases. EMBO J (1989) 3.26
Direct sequencing of the amplified structural gene and promoter for the extended-broad-spectrum beta-lactamase TEM-9 (RHH-1) of Klebsiella pneumoniae. Plasmid (1990) 3.19
Two new mechanisms of macrolide resistance in clinical strains of Streptococcus pneumoniae from Eastern Europe and North America. Antimicrob Agents Chemother (2000) 3.00
Shuttle vectors containing a multiple cloning site and a lacZ alpha gene for conjugal transfer of DNA from Escherichia coli to gram-positive bacteria. Gene (1991) 3.00
Structural relationship between the genes encoding 3'-aminoglycoside phosphotransferases in Campylobacter and in gram-positive cocci. Ann Inst Pasteur Microbiol (1986) 2.92
Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria. Antimicrob Agents Chemother (1991) 2.91
Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine. Mol Microbiol (1994) 2.90
Nomenclature for new tetracycline resistance determinants. Antimicrob Agents Chemother (1999) 2.89
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583. J Bacteriol (1996) 2.87
Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci. Mol Microbiol (1996) 2.84
Distribution of erythromycin esterase and rRNA methylase genes in members of the family Enterobacteriaceae highly resistant to erythromycin. Antimicrob Agents Chemother (1987) 2.80
Sequence of the vanB and ddl genes encoding D-alanine:D-lactate and D-alanine:D-alanine ligases in vancomycin-resistant Enterococcus faecalis V583. Gene (1994) 2.76
Sequence of the genes blaT-1B and blaT-2. Gene (1991) 2.72
Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548. Antimicrob Agents Chemother (2005) 2.71
Characterization of the plasmid genes blaT-4 and blaT-5 which encode the broad-spectrum beta-lactamases TEM-4 and TEM-5 in enterobacteriaceae. Gene (1989) 2.69
Tn1545: a conjugative shuttle transposon. Mol Gen Genet (1987) 2.65
Analysis of genes encoding D-alanine-D-alanine ligase-related enzymes in Enterococcus casseliflavus and Enterococcus flavescens. Antimicrob Agents Chemother (1994) 2.65
Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus. Antimicrob Agents Chemother (1998) 2.58
Conjugative plasmid transfer from Enterococcus faecalis to Escherichia coli. J Bacteriol (1988) 2.58
A pair of mobilizable shuttle vectors conferring resistance to spectinomycin for molecular cloning in Escherichia coli and in gram-positive bacteria. Nucleic Acids Res (1990) 2.57
Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. Antimicrob Agents Chemother (1993) 2.56
Transferable plasmid-mediated resistance to streptomycin in a clinical isolate of Yersinia pestis. Emerg Infect Dis (2001) 2.50
VanD-type glycopeptide-resistant Enterococcus faecium BM4339. Antimicrob Agents Chemother (1997) 2.50
Detection of erythromycin resistance by the polymerase chain reaction using primers in conserved regions of erm rRNA methylase genes. Antimicrob Agents Chemother (1990) 2.49
The vanB gene confers various levels of self-transferable resistance to vancomycin in enterococci. J Infect Dis (1993) 2.49
Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase IV mutants of Streptococcus pneumoniae selected in vitro. Antimicrob Agents Chemother (1996) 2.48
Nomenclature for tetracycline resistance determinants. Antimicrob Agents Chemother (1989) 2.46
An integrative vector exploiting the transposition properties of Tn1545 for insertional mutagenesis and cloning of genes from gram-positive bacteria. Gene (1991) 2.42
TEM beta-lactamase mutants hydrolysing third-generation cephalosporins. A kinetic and molecular modelling analysis. J Mol Biol (1994) 2.35
Effects of combinations of beta-lactams, daptomycin, gentamicin, and glycopeptides against glycopeptide-resistant enterococci. Antimicrob Agents Chemother (1991) 2.31
Updated sequence information for TEM beta-lactamase genes. Antimicrob Agents Chemother (1999) 2.31
Functional gene transfer from intracellular bacteria to mammalian cells. Nat Biotechnol (1998) 2.30
Structural relationship between the vancomycin resistance protein VanH and 2-hydroxycarboxylic acid dehydrogenases. Gene (1991) 2.28
Mechanisms of antibiotic resistance in Campylobacter species. Antimicrob Agents Chemother (1988) 2.26
Susceptibility of Campylobacter pyloridis to 20 antimicrobial agents. Antimicrob Agents Chemother (1986) 2.26
Molecular characterization of integrons in Acinetobacter baumannii: description of a hybrid class 2 integron. Antimicrob Agents Chemother (2000) 2.25
Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae. Antimicrob Agents Chemother (2001) 2.22
Plasmid-medicated aminoglycoside phosphotransferase of broad substrate range that phosphorylates amikacin. Antimicrob Agents Chemother (1977) 2.22
Translocation of sequences encoding antibiotic resistance from the chromosome to a receptor plasmid in Salmonella ordonez. Mol Gen Genet (1981) 2.22
Resistance to glycopeptides in enterococci. Clin Infect Dis (1997) 2.21
Characterization of the chromosomal aac(6')-Ii gene specific for Enterococcus faecium. Antimicrob Agents Chemother (1993) 2.19
The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J Bacteriol (1997) 2.19
Comparability of antimicrobial susceptibility test results from 22 European countries and Israel: an external quality assurance exercise of the European Antimicrobial Resistance Surveillance System (EARSS) in collaboration with the United Kingdom National External Quality Assurance Scheme (UK NEQAS). J Antimicrob Chemother (2002) 2.14
Analysis of peptidoglycan precursors in vancomycin-resistant Enterococcus gallinarum BM4174. Biochem J (1994) 2.10
Will avilamycin convert ziracine into zerocine? Emerg Infect Dis (2000) 2.10
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models. Mol Biochem Parasitol (2000) 2.10
The vanZ gene of Tn1546 from Enterococcus faecium BM4147 confers resistance to teicoplanin. Gene (1995) 2.09
Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp. Microbiology (2000) 2.08
Origin and evolution of genes specifying resistance to macrolide, lincosamide and streptogramin antibiotics: data and hypotheses. J Antimicrob Chemother (1987) 2.06
Contribution of VanY D,D-carboxypeptidase to glycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors. Antimicrob Agents Chemother (1994) 2.01
Evidence for in vivo incorporation of D-lactate into peptidoglycan precursors of vancomycin-resistant enterococci. Antimicrob Agents Chemother (1992) 1.99
TEM-4, a new plasmid-mediated beta-lactamase that hydrolyzes broad-spectrum cephalosporins in a clinical isolate of Escherichia coli. Antimicrob Agents Chemother (1989) 1.98
Nucleotide sequence of the gene ereA encoding the erythromycin esterase in Escherichia coli. Gene (1985) 1.96
VanE, a new type of acquired glycopeptide resistance in Enterococcus faecalis BM4405. Antimicrob Agents Chemother (1999) 1.95
[Antibiogram Committee of the French Microbiology Society. Report 2000-2001]. Pathol Biol (Paris) (2000) 1.94
Transferable plasmid-mediated antibiotic resistance in Listeria monocytogenes. Lancet (1990) 1.94
A spontaneous point mutation in the aac(6')-Ib' gene results in altered substrate specificity of aminoglycoside 6'-N-acetyltransferase of a Pseudomonas fluorescens strain. FEMS Microbiol Lett (1994) 1.93
Conjugal transfer of the vancomycin resistance determinant vanB between enterococci involves the movement of large genetic elements from chromosome to chromosome. FEMS Microbiol Lett (1994) 1.91
The integration-excision system of the conjugative transposon Tn 1545 is structurally and functionally related to those of lambdoid phages. Mol Microbiol (1990) 1.90
Transferable amikacin resistance in Acinetobacter spp. due to a new type of 3'-aminoglycoside phosphotransferase. Antimicrob Agents Chemother (1988) 1.90
Emergence of high-level resistance to glycopeptides in Enterococcus gallinarum and Enterococcus casseliflavus. Antimicrob Agents Chemother (1994) 1.89
Resistance of enterococci to aminoglycosides and glycopeptides. Clin Infect Dis (1992) 1.89
Enzymic hydrolysis of erythromycin by a strain of Escherichia coli. A new mechanism of resistance. J Antibiot (Tokyo) (1984) 1.85
Inactivation of lincosaminide antibiotics in Staphylococcus. Identification of lincosaminide O-nucleotidyltransferases and comparison of the corresponding resistance genes. J Biol Chem (1988) 1.83
Contribution of two different mechanisms to erythromycin resistance in Escherichia coli. Antimicrob Agents Chemother (1986) 1.82
Nucleotide sequence of Acinetobacter baumannii aphA-6 gene: evolutionary and functional implications of sequence homologies with nucleotide-binding proteins, kinases and other aminoglycoside-modifying enzymes. Mol Microbiol (1988) 1.80
Physical analysis of the conjugative shuttle transposon Tn1545. Plasmid (1987) 1.79
Analysis of the nucleotide sequence of the ereB gene encoding the erythromycin esterase type II. Nucleic Acids Res (1986) 1.79