1
|
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel.
|
Science
|
2002
|
4.49
|
2
|
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle.
|
Nat Med
|
2009
|
3.27
|
3
|
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias.
|
Cell
|
2005
|
3.01
|
4
|
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.
|
Proc Natl Acad Sci U S A
|
2006
|
2.81
|
5
|
Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice.
|
J Clin Invest
|
2008
|
2.45
|
6
|
The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.
|
J Clin Invest
|
2002
|
2.26
|
7
|
Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.
|
Proc Natl Acad Sci U S A
|
2008
|
2.16
|
8
|
Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.
|
Cell Metab
|
2011
|
2.06
|
9
|
Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure.
|
Proc Natl Acad Sci U S A
|
2005
|
1.99
|
10
|
A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors.
|
Heart Rhythm
|
2007
|
1.98
|
11
|
Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias.
|
Proc Natl Acad Sci U S A
|
2006
|
1.87
|
12
|
Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
|
Circ Res
|
2012
|
1.80
|
13
|
Role of chronic ryanodine receptor phosphorylation in heart failure and β-adrenergic receptor blockade in mice.
|
J Clin Invest
|
2010
|
1.77
|
14
|
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.
|
Proc Natl Acad Sci U S A
|
2010
|
1.67
|
15
|
Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure.
|
Proc Natl Acad Sci U S A
|
2010
|
1.63
|
16
|
Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.
|
J Clin Invest
|
2010
|
1.60
|
17
|
Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.
|
J Clin Invest
|
2011
|
1.41
|
18
|
Calcium release channel RyR2 regulates insulin release and glucose homeostasis.
|
J Clin Invest
|
2015
|
1.38
|
19
|
Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?
|
Circulation
|
2002
|
1.16
|
20
|
Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties.
|
J Am Coll Cardiol
|
2005
|
1.13
|
21
|
Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice.
|
Proc Natl Acad Sci U S A
|
2006
|
1.13
|
22
|
Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex.
|
J Biol Chem
|
2002
|
1.09
|
23
|
Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization.
|
J Biol Chem
|
2004
|
0.98
|
24
|
Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor.
|
J Physiol
|
2012
|
0.97
|
25
|
Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers.
|
Trends Cardiovasc Med
|
2002
|
0.96
|
26
|
A novel ryanodine receptor mutation linked to sudden death increases sensitivity to cytosolic calcium.
|
Circ Res
|
2011
|
0.96
|
27
|
Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.
|
Skelet Muscle
|
2012
|
0.95
|
28
|
Nonshivering thermogenesis protects against defective calcium handling in muscle.
|
FASEB J
|
2008
|
0.95
|
29
|
Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.
|
FASEB J
|
2011
|
0.94
|
30
|
Calcium release channel RyR2 regulates insulin release and glucose homeostasis.
|
J Clin Invest
|
2015
|
0.87
|
31
|
Bradycardic therapy improves left ventricular function and remodeling in dogs with coronary embolization-induced chronic heart failure.
|
J Pharmacol Exp Ther
|
2007
|
0.85
|
32
|
Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure.
|
J Heart Lung Transplant
|
2013
|
0.83
|
33
|
Reply from Daniel C. Andersson, Matthew J. Betzenhauser, Steven Reiken, Alisa Umanskaya, Takayuki Shiomi and Andrew R. Marks.
|
J Physiol
|
2013
|
0.75
|