Published in J Comp Neurol on February 18, 2002
Pharmacology of P2X channels. Pflugers Arch (2006) 2.14
Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. J Neurosci (2009) 1.64
P2X2 receptors differentiate placodal vs. neural crest C-fiber phenotypes innervating guinea pig lungs and esophagus. Am J Physiol Lung Cell Mol Physiol (2008) 1.35
Molecular and functional properties of P2X receptors--recent progress and persisting challenges. Purinergic Signal (2012) 1.31
Taste buds as peripheral chemosensory processors. Semin Cell Dev Biol (2012) 1.20
Nucleotide signaling in nervous system development. Pflugers Arch (2006) 1.18
Knocking out P2X receptors reduces transmitter secretion in taste buds. J Neurosci (2011) 1.03
Development of nerves expressing P2X3 receptors in the myenteric plexus of rat stomach. Histochem Cell Biol (2004) 0.95
Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol (2004) 0.90
Developmentally regulated expression of the P2X3 receptor in the mouse cochlea. Histochem Cell Biol (2005) 0.87
New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic Signal (2007) 0.87
P2X7 receptors in satellite glial cells mediate high functional expression of P2X3 receptors in immature dorsal root ganglion neurons. Mol Pain (2012) 0.86
Purines as potential morphogens during embryonic development. Purinergic Signal (2012) 0.82
Opposing effects of P2X(7) and P2Y purine/pyrimidine-preferring receptors on proliferation of astrocytes induced by fibroblast growth factor-2: implications for CNS development, injury, and repair. J Neurosci Res (2008) 0.81
Prenatal expression of purinergic receptor P2X3 in human dorsal root ganglion. Purinergic Signal (2011) 0.80
Ectodermal P2X receptor function plays a pivotal role in craniofacial development of the zebrafish. Purinergic Signal (2009) 0.79
Pharmacological and molecular characterization of functional P2 receptors in rat embryonic cardiomyocytes. Purinergic Signal (2014) 0.79
Purinergic signalling during development and ageing. Purinergic Signal (2015) 0.75
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev (2006) 5.28
Purinergic signalling in neuron-glia interactions. Nat Rev Neurosci (2006) 3.17
Purinergic signalling in the nervous system: an overview. Trends Neurosci (2008) 2.86
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med (2004) 2.59
Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci (2003) 2.37
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP. J Physiol (2005) 2.25
Pharmacology of P2X channels. Pflugers Arch (2006) 2.14
P2 receptors in cardiovascular regulation and disease. Purinergic Signal (2007) 1.91
P2 receptors and cancer. Trends Pharmacol Sci (2006) 1.80
Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia. J Neurosci (2003) 1.59
Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladder. J Physiol (2002) 1.45
Pharmacological and biophysical properties of the human P2X5 receptor. Mol Pharmacol (2003) 1.44
Purinergic signalling and bone remodelling. Curr Opin Pharmacol (2010) 1.43
P2X receptors and their role in female idiopathic detrusor instability. J Urol (2002) 1.36
Extracellular nucleotides block bone mineralization in vitro: evidence for dual inhibitory mechanisms involving both P2Y2 receptors and pyrophosphate. Endocrinology (2007) 1.32
The double life of ATP. Sci Am (2009) 1.31
Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation. Immunity (2003) 1.31
Osteoblast responses to nucleotides increase during differentiation. Bone (2006) 1.30
Purinergic signaling along the renal tubule: the current state of play. News Physiol Sci (2003) 1.29
Localisation of P2Y1 and P2Y4 receptors in dorsal root, nodose and trigeminal ganglia of the rat. Histochem Cell Biol (2003) 1.27
ATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cells. J Cell Biol (2002) 1.24
Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum. Gastroenterology (2003) 1.24
Regulation of bone resorption and formation by purines and pyrimidines. Trends Pharmacol Sci (2003) 1.23
Purinergic component of mechanosensory transduction is increased in a rat model of colitis. Am J Physiol Gastrointest Liver Physiol (2004) 1.21
Purinergic signalling and cancer. Purinergic Signal (2013) 1.18
Hypoxia stimulates vesicular ATP release from rat osteoblasts. J Cell Physiol (2009) 1.18
Activity of Novel Adenine Nucleotide Derivatives as Agonists and Antagonists at Recombinant Rat P2X Receptors. Drug Dev Res (2000) 1.16
Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. J Invest Dermatol (2003) 1.16
Purinoceptors on neuroglia. Mol Neurobiol (2009) 1.11
An evolutionary history of P2X receptors. Purinergic Signal (2008) 1.11
Expression of purinergic receptors in non-melanoma skin cancers and their functional roles in A431 cells. J Invest Dermatol (2003) 1.11
P2 receptor web: complexity and fine-tuning. Pharmacol Ther (2006) 1.09
Purinergic signalling in autonomic control. Trends Neurosci (2009) 1.08
P2X7 deficiency attenuates renal injury in experimental glomerulonephritis. J Am Soc Nephrol (2009) 1.08
Microglia: proliferation and activation driven by the P2X7 receptor. Int J Biochem Cell Biol (2010) 1.07
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. Br J Pharmacol (2010) 1.07
Involvement of purinergic signaling in cardiovascular diseases. Drug News Perspect (2003) 1.07
Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum. Histochem Cell Biol (2002) 1.06
Abundant and dynamic expression of G protein-coupled P2Y receptors in mammalian development. Dev Dyn (2003) 1.05
Pathophysiology of astroglial purinergic signalling. Purinergic Signal (2012) 1.03
Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models. Kidney Int (2004) 1.03
Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochem Pharmacol (2005) 1.03
Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis. J Invest Dermatol (2003) 1.00
P2X2 and P2X3 purinoceptors in the rat enteric nervous system. Histochem Cell Biol (2004) 1.00
Heteromultimeric P2X(1/2) receptors show a novel sensitivity to extracellular pH. J Pharmacol Exp Ther (2002) 0.99
Expression of P2X receptors on rat microglial cells during early development. Glia (2005) 0.99
P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation. Am J Physiol Gastrointest Liver Physiol (2005) 0.97
ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: a novel role for the P2Y2 receptor in bone remodeling. J Cell Biochem (2002) 0.97
Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists. Drug Dev Res (1998) 0.96
Extrinsic purinergic regulation of neural stem/progenitor cells: implications for CNS development and repair. Stem Cell Rev (2012) 0.96
Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model. Behav Brain Res (2011) 0.96
Purinergic receptor-mediated effects of adenosine 5'-triphosphate in urological malignant diseases. Int J Urol (2008) 0.95
P2Y purinergic receptors regulate the growth of human melanomas. Cancer Lett (2004) 0.95
Development of nerves expressing P2X3 receptors in the myenteric plexus of rat stomach. Histochem Cell Biol (2004) 0.95
Functional up-regulation of P2X 3 receptors in the chronically compressed dorsal root ganglion. Pain (2008) 0.95
The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors. Bone (2012) 0.94
The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor. Trends Pharmacol Sci (2005) 0.93
Investigation of the effects of P2 purinoceptor ligands on the micturition reflex in female urethane-anaesthetized rats. Br J Pharmacol (2004) 0.93
The purinergic component of human vas deferens contraction. Fertil Steril (2006) 0.91
Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures. FASEB J (2004) 0.91
Expression of P2X6 receptors in the enteric nervous system of the rat gastrointestinal tract. Histochem Cell Biol (2009) 0.91
Tissue distribution of P2X4 receptors studied with an ectodomain antibody. Cell Tissue Res (2003) 0.91
Changes in expression of P2X purinoceptors in rat cerebellum during postnatal development. Brain Res Dev Brain Res (2005) 0.90
Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol (2004) 0.90
P2X(7) receptors are expressed during mouse nephrogenesis and in collecting duct cysts of the cpk/cpk mouse. Exp Nephrol (2002) 0.89
P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats. Mol Cell Endocrinol (2003) 0.89
The distribution of P2X5 purinergic receptors in the enteric nervous system of mouse. Cell Tissue Res (2004) 0.89
Effect of extracellular ATP on the growth of hormone-refractory prostate cancer in vivo. BJU Int (2008) 0.88
An in vivo model of melanoma: treatment with ATP. Purinergic Signal (2009) 0.88
Distribution of P2Y2 receptors in the guinea pig enteric nervous system and its coexistence with P2X2 and P2X3 receptors, neuropeptide Y, nitric oxide synthase and calretinin. Histochem Cell Biol (2005) 0.88
Localization of P2X and P2Y receptors in dorsal root ganglia of the cat. J Histochem Cytochem (2005) 0.88
P2 receptors in human heart: upregulation of P2X6 in patients undergoing heart transplantation, interaction with TNFalpha and potential role in myocardial cell death. J Mol Cell Cardiol (2005) 0.88
Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1). Mol Pharmacol (2002) 0.87
P2X receptors and their roles in astroglia in the central and peripheral nervous system. Neuroscientist (2011) 0.87
Gap junction reduction in cardiomyocytes following transforming growth factor-beta treatment and Trypanosoma cruzi infection. Mem Inst Oswaldo Cruz (2009) 0.87
Human melanomas express functional P2 X(7) receptors. Cell Tissue Res (2005) 0.87
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control. Neuropharmacology (2005) 0.87
Inhibition of G protein-coupled P2Y2 receptor induced analgesia in a rat model of trigeminal neuropathic pain. Mol Pain (2014) 0.87
The P2Y(6) receptor stimulates bone resorption by osteoclasts. Endocrinology (2011) 0.86
Postnatal development of P2 receptors in the murine gastrointestinal tract. Neuropharmacology (2006) 0.86
Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig. Neuropharmacology (2004) 0.86
Oxytocin is expressed by both intrinsic sensory and secretomotor neurons in the enteric nervous system of guinea pig. Cell Tissue Res (2011) 0.86
Distribution of P2Y6 and P2Y12 receptor: their colocalization with calbindin, calretinin and nitric oxide synthase in the guinea pig enteric nervous system. Histochem Cell Biol (2005) 0.86
Region-specific distribution of the P2Y4 receptor in enteric glial cells and interstitial cells of Cajal within the guinea-pig gastrointestinal tract. Auton Neurosci (2006) 0.85
Purinergic receptor-mediated effects of ATP in high-grade bladder cancer. BJU Int (2007) 0.85
Biology of purinergic signalling: its ancient evolutionary roots, its omnipresence and its multiple functional significance. Bioessays (2014) 0.85
Immunolocalisation of P2X and P2Y nucleotide receptors in the rat nasal mucosa. Cell Tissue Res (2004) 0.85
Expression of P2X receptors on immune cells in the rat liver during postnatal development. Histochem Cell Biol (2006) 0.84
P2X1 receptors are closely associated with connexin 43 in human ventricular myocardium. Int J Cardiol (2005) 0.84
Link between cancer and Alzheimer disease via oxidative stress induced by nitric oxide-dependent mitochondrial DNA overproliferation and deletion. Oxid Med Cell Longev (2013) 0.84
Purinergic receptor expression in the regeneration epidermis in a rat model of normal and delayed wound healing. Exp Dermatol (2003) 0.84
Microglial morphology and its transformation after challenge by extracellular ATP in vitro. J Neurosci Res (2006) 0.84
P2Y2 receptor-mediated modulation of estrogen-induced proliferation of breast cancer cells. Mol Cell Endocrinol (2011) 0.83
Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages. Immunobiology (2010) 0.83
Sympathetic innervation of human mesenteric artery and vein. J Vasc Res (2008) 0.83
Unusual absence of endothelium-dependent or -independent vasodilatation to purines or pyrimidines in the rat renal artery. Kidney Int (2003) 0.83
Pathological roles of purinergic signaling in the liver. J Hepatol (2012) 0.82
The effect of neonatal nerve injury on the expression of heat shock proteins in developing rat motoneurones. J Neurotrauma (2002) 0.82
Estrogen modulation of peripheral pain signal transduction: involvement of P2X(3) receptors. Purinergic Signal (2011) 0.82
ATP signalling in epilepsy. Purinergic Signal (2008) 0.82