PubRank

Roger J Daly

Author PubWeight™ 71.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 2012 8.31
2 Dual-specificity phosphatases: critical regulators with diverse cellular targets. Biochem J 2009 3.98
3 Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature 2013 2.33
4 Cyclin D1, EMS1 and 11q13 amplification in breast cancer. Breast Cancer Res Treat 2003 2.14
5 A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton. J Biol Chem 2003 1.99
6 Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice. EMBO J 2004 1.97
7 PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality. Int J Cancer 2010 1.89
8 Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol Cell 2005 1.84
9 Cell cycle control in breast cancer cells. J Cell Biochem 2006 1.68
10 Nedd4 controls animal growth by regulating IGF-1 signaling. Sci Signal 2008 1.67
11 Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life. Mol Cell Biol 2007 1.63
12 Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells. Cancer Res 2010 1.62
13 Function, regulation and pathological roles of the Gab/DOS docking proteins. Cell Commun Signal 2009 1.59
14 Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein. J Biol Chem 2005 1.32
15 PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA. Arterioscler Thromb Vasc Biol 2010 1.24
16 Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib. Cancer Res 2007 1.14
17 PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2. EMBO J 2002 1.14
18 Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor. Cancer Res 2005 1.11
19 Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7. J Biol Chem 2002 1.10
20 Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. EMBO J 2008 1.06
21 Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One 2011 1.06
22 Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis. Mol Endocrinol 2009 1.04
23 Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. Biochemistry 2009 1.04
24 KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling. Biochim Biophys Acta 2008 1.02
25 Adapter protein connections: the MRL and Grb7 protein families. Growth Factors 2005 1.02
26 Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity. Oncogene 2005 1.01
27 Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development. Int J Cancer 2010 1.01
28 Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway. Cancer Res 2013 0.98
29 p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells. Cancer Res 2003 0.98
30 Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2. J Biomol NMR 2003 0.98
31 Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel. EMBO Rep 2010 0.97
32 Molecular determinants of Grb14-mediated inhibition of insulin signaling. Mol Endocrinol 2009 0.97
33 Grb10 regulates the development of fiber number in skeletal muscle. FASEB J 2012 0.96
34 Grb7-based molecular therapeutics in cancer. Expert Rev Mol Med 2003 0.96
35 Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation. J Cell Physiol 2014 0.93
36 TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. Mol Cell Biol 2012 0.93
37 Global characterization of signalling networks associated with tamoxifen resistance in breast cancer. FEBS J 2013 0.91
38 Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin. Mol Biol Cell 2007 0.89
39 Targeting the human kinome for cancer therapy: current perspectives. Crit Rev Oncog 2012 0.87
40 Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation. Mol Biol Cell 2010 0.87
41 Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells. FEBS J 2013 0.85
42 Cortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells. Mol Cell Biol 2010 0.85
43 Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancer. Mol Cancer Ther 2013 0.85
44 Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF-7 human breast cancer cells. J Cell Physiol 2005 0.84
45 RON is not a prognostic marker for resectable pancreatic cancer. BMC Cancer 2012 0.83
46 The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells. Biochim Biophys Acta 2012 0.82
47 DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs. Biochim Biophys Acta 2010 0.82
48 Docking proteins. FEBS J 2010 0.81
49 Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status. Int J Cancer 2010 0.81
50 How to Grb2 a Gab. Structure 2009 0.81
51 Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways. Breast Cancer Res 2014 0.79
52 Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling. J Proteome Res 2013 0.78
53 Signalling through the grapevine. EMBO Rep 2012 0.77
54 New insights into signalling networks regulating breast cancer stem cells. Breast Cancer Res 2012 0.75
55 Distinction at the leading edge of the cell. Bioessays 2005 0.75
56 Professor Robert Sutherland FAA, AO (1947-2012). Horm Mol Biol Clin Investig 2013 0.75