Published in Transgenic Res on December 01, 2001
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc Natl Acad Sci U S A (2006) 5.69
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Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A (2003) 4.69
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Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis. Mol Cell Biol (2004) 1.33
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Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk. EMBO J (2015) 1.00
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Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis. J Biol Chem (2015) 0.97
Somatic expression of PyMT or activated ErbB2 induces estrogen-independent mammary tumorigenesis. Neoplasia (2010) 0.96
Biogenesis and function of mouse mammary epithelium depends on the presence of functional alpha-catenin. Mech Dev (2004) 0.94
Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Dev Biol (2011) 0.93
Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile. PLoS One (2012) 0.93
Parathyroid hormone-related protein is not required for normal ductal or alveolar development in the post-natal mammary gland. PLoS One (2011) 0.92
Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors. PLoS One (2012) 0.92
TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involution. J Cell Physiol (2009) 0.91
Xanthine oxidoreductase mediates membrane docking of milk-fat droplets but is not essential for apocrine lipid secretion. J Physiol (2016) 0.91
Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice. Neoplasia (2008) 0.91
Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice. PLoS One (2010) 0.90
Essential role of Orai1 store-operated calcium channels in lactation. Proc Natl Acad Sci U S A (2015) 0.90
Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium. Breast Cancer Res (2013) 0.90
The estrogen-responsive Agr2 gene regulates mammary epithelial proliferation and facilitates lobuloalveolar development. Dev Biol (2012) 0.90
MMTV-Cre transgenes can adversely affect lactation: considerations for conditional gene deletion in mammary tissue. Anal Biochem (2011) 0.89
Conditional Wwox deletion in mouse mammary gland by means of two Cre recombinase approaches. PLoS One (2012) 0.89
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Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity. Dev Biol (2008) 0.89
VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis. Am J Pathol (2010) 0.87
CrkII transgene induces atypical mammary gland development and tumorigenesis. Am J Pathol (2009) 0.87
Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes. Genes Cancer (2012) 0.86
SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines. JAKSTAT (2013) 0.86
Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet (2014) 0.86
Adhesion in mammary development: novel roles for E-cadherin in individual and collective cell migration. Curr Top Dev Biol (2015) 0.85
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo. PLoS One (2012) 0.85
Tissue-Specific Contributions of Paternally Expressed Gene 3 in Lactation and Maternal Care of Mus musculus. PLoS One (2015) 0.85
Conditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation. Dev Biol (2010) 0.84
A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis. Neoplasia (2008) 0.84
Genetically engineered mice as experimental tools to dissect the critical events in breast cancer. Adv Cancer Res (2014) 0.84
Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress. Proc Natl Acad Sci U S A (2014) 0.84
Ovarian VEGF(165)b expression regulates follicular development, corpus luteum function and fertility. Reproduction (2012) 0.83
SOCS3 deletion in B cells alters cytokine responses and germinal center output. J Immunol (2011) 0.83
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Dis Model Mech (2013) 0.82
Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland. Free Radic Res (2012) 0.82
Lactation defect in a widely used MMTV-Cre transgenic line of mice. PLoS One (2011) 0.82
MiR-193b and miR-365-1 are not required for the development and function of brown fat in the mouse. RNA Biol (2013) 0.81
MMTV/LTR Promoter-Driven Transgenic Expression of EpCAM Leads to the Development of Large Pancreatic Islets. J Histochem Cytochem (2015) 0.81
MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer. Oncotarget (2015) 0.80
N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland. J Biol Chem (2012) 0.80
Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation. Biochim Biophys Acta (2013) 0.80
Differential requirement of GRP94 and GRP78 in mammary gland development. Sci Rep (2014) 0.80
IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors. Cancer Res (2014) 0.80
Loss of vitamin D receptor signaling from the mammary epithelium or adipose tissue alters pubertal glandular development. Am J Physiol Endocrinol Metab (2014) 0.80
The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis. PLoS Genet (2014) 0.79
Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene. PLoS One (2015) 0.79
Abnormal Mammary Adipose Tissue Environment of Brca1 Mutant Mice Show a Persistent Deposition of Highly Vascularized Multilocular Adipocytes. J Cancer Sci Ther (2011) 0.79
Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice. Toxicol Lett (2012) 0.79
The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis. Cell Rep (2016) 0.78
Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation. Oncotarget (2016) 0.78
Matriptase deletion initiates a Sjögren's syndrome-like disease in mice. PLoS One (2014) 0.78
Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach. Genome Biol (2015) 0.78
Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer. Nat Cell Biol (2016) 0.78
A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon. PLoS One (2016) 0.77
Epigenetic instability at imprinting control regions in a Kras(G12D)-induced T-cell neoplasm. Epigenetics (2015) 0.77
Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein. Cancer Res (2016) 0.77
Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling. Mol Cell Biol (2016) 0.77
Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours. Nat Cell Biol (2016) 0.77
Smad4 loss in mouse keratinocytes leads to increased susceptibility to UV carcinogenesis with reduced Ercc1-mediated DNA repair. J Invest Dermatol (2013) 0.77
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