Published in J Am Chem Soc on February 06, 2002
Structure determination of membrane proteins by NMR spectroscopy. Chem Rev (2004) 3.25
De novo design of a transmembrane Zn²⁺-transporting four-helix bundle. Science (2014) 2.39
Amphotericin forms an extramembranous and fungicidal sterol sponge. Nat Chem Biol (2014) 1.96
Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR. Proc Natl Acad Sci U S A (2006) 1.87
Solid-state NMR investigation of the depth of insertion of protegrin-1 in lipid bilayers using paramagnetic Mn2+. Biophys J (2003) 1.55
Membrane protein structure and dynamics from NMR spectroscopy. Annu Rev Phys Chem (2011) 1.43
The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils. J Am Chem Soc (2011) 1.37
Conformational changes of an ion channel detected through water-protein interactions using solid-state NMR spectroscopy. J Am Chem Soc (2010) 1.33
Water-protein interactions of an arginine-rich membrane peptide in lipid bilayers investigated by solid-state nuclear magnetic resonance spectroscopy. J Phys Chem B (2010) 1.17
The distribution of lipid attached spin probes in bilayers: application to membrane protein topology. Biophys J (2003) 1.14
Structure and dynamics of cationic membrane peptides and proteins: insights from solid-state NMR. Protein Sci (2011) 1.13
Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR. Biochemistry (2010) 1.09
The diversity of the liquid ordered (Lo) phase of phosphatidylcholine/cholesterol membranes: a variable temperature multinuclear solid-state NMR and x-ray diffraction study. Biophys J (2006) 1.05
Asymmetric insertion of membrane proteins in lipid bilayers by solid-state NMR paramagnetic relaxation enhancement: a cell-penetrating Peptide example. J Am Chem Soc (2008) 1.03
The membrane-bound structure and topology of a human α-defensin indicate a dimer pore mechanism for membrane disruption. Biochemistry (2010) 1.01
Structure and mechanism of beta-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy. Mol Biosyst (2009) 1.00
Conformational analysis of the full-length M2 protein of the influenza A virus using solid-state NMR. Protein Sci (2013) 0.94
Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance. Biochemistry (2014) 0.93
Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide from solid-state NMR. Biochim Biophys Acta (2008) 0.91
Structures of β-hairpin antimicrobial protegrin peptides in lipopolysaccharide membranes: mechanism of gram selectivity obtained from solid-state nuclear magnetic resonance. Biochemistry (2011) 0.88
Membrane-dependent conformation, dynamics, and lipid interactions of the fusion peptide of the paramyxovirus PIV5 from solid-state NMR. J Mol Biol (2012) 0.87
2D 1H-31P solid-state NMR studies of the dependence of inter-bilayer water dynamics on lipid headgroup structure and membrane peptides. J Magn Reson (2008) 0.87
Structural interactions between lipids, water and S1-S4 voltage-sensing domains. J Mol Biol (2012) 0.86
Penetration depth of surfactant peptide KL4 into membranes is determined by fatty acid saturation. Biophys J (2009) 0.85
Probing membrane protein structure using water polarization transfer solid-state NMR. J Magn Reson (2014) 0.84
Structure of the disulfide bond generating membrane protein DsbB in the lipid bilayer. J Mol Biol (2013) 0.83
Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance. Biochemistry (2010) 0.83
Residue-specific membrane location of peptides and proteins using specifically and extensively deuterated lipids and ¹³C-²H rotational-echo double-resonance solid-state NMR. J Biomol NMR (2012) 0.82
Conformation and lipid interaction of the fusion peptide of the paramyxovirus PIV5 in anionic and negative-curvature membranes from solid-state NMR. J Am Chem Soc (2014) 0.82
Magnetization transfer from inhomogeneously broadened lines: A potential marker for myelin. Magn Reson Med (2014) 0.81
Investigation of the curvature induction and membrane localization of the influenza virus M2 protein using static and off-magic-angle spinning solid-state nuclear magnetic resonance of oriented bicelles. Biochemistry (2015) 0.80
Determining the depth of insertion of dynamically invisible membrane peptides by gel-phase ¹H spin diffusion heteronuclear correlation NMR. J Biomol NMR (2013) 0.80
Cationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMR. Amino Acids (2012) 0.79
Viral fusion protein transmembrane domain adopts β-strand structure to facilitate membrane topological changes for virus-cell fusion. Proc Natl Acad Sci U S A (2015) 0.79
Magic-angle-spinning NMR techniques for measuring long-range distances in biological macromolecules. Acc Chem Res (2013) 0.79
Minimizing the effects of magnetization transfer asymmetry on inhomogeneous magnetization transfer (ihMT) at ultra-high magnetic field (11.75 T). MAGMA (2016) 0.77
Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin. PLoS One (2015) 0.76
Computational studies of colicin insertion into membranes: the closed state. Proteins (2010) 0.76
Multiple locations of peptides in the hydrocarbon core of gel-phase membranes revealed by peptide (13)C to lipid (2)H rotational-echo double-resonance solid-state nuclear magnetic resonance. Biochemistry (2015) 0.76
Solid-State NMR Investigation of the Conformation, Proton Conduction, and Hydration of the Influenza B Virus M2 Transmembrane Proton Channel. J Am Chem Soc (2016) 0.75
Intramolecular 1H-13C distance measurement in uniformly 13C, 15N labeled peptides by solid-state NMR. Solid State Nucl Magn Reson (2012) 0.75
Structural Thermodynamics of myr-Src(2-19) Binding to Phospholipid Membranes. Biophys J (2015) 0.75
Probing Hydronium Ion Histidine NH Exchange Rate Constants in the M2 Channel via Indirect Observation of Dipolar-Dephased (15)N Signals in Magic-Angle-Spinning NMR. J Am Chem Soc (2016) 0.75
REDOR solid-state NMR as a probe of the membrane locations of membrane-associated peptides and proteins. J Magn Reson (2015) 0.75
NMR chemical shift pattern changed by ammonium sulfate precipitation in cyanobacterial phytochrome Cph1. Front Mol Biosci (2015) 0.75
Trans and surface membrane bound zervamicin IIB: 13C-MAOSS-NMR at high spinning speed. J Biomol NMR (2006) 0.75
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell (2004) 6.00
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature (2010) 3.95
Mechanisms of proton conduction and gating in influenza M2 proton channels from solid-state NMR. Science (2010) 2.40
Structure of amantadine-bound M2 transmembrane peptide of influenza A in lipid bilayers from magic-angle-spinning solid-state NMR: the role of Ser31 in amantadine binding. J Mol Biol (2008) 2.15
Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells. Mol Cell Biol (2007) 2.14
Mechanism of radiation-induced bystander effects: a unifying model. J Pharm Pharmacol (2008) 2.07
Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel. Proc Natl Acad Sci U S A (2008) 2.07
Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR. Proc Natl Acad Sci U S A (2006) 1.87
Rationally improving LOV domain-based photoswitches. Nat Methods (2010) 1.72
Structure and function of the influenza A M2 proton channel. Biochemistry (2009) 1.67
Determining the orientation of uniaxially rotating membrane proteins using unoriented samples: a 2H, 13C, AND 15N solid-state NMR investigation of the dynamics and orientation of a transmembrane helical bundle. J Am Chem Soc (2007) 1.63
Phosphate-mediated arginine insertion into lipid membranes and pore formation by a cationic membrane peptide from solid-state NMR. J Am Chem Soc (2007) 1.63
Structure and interactions of plant cell-wall polysaccharides by two- and three-dimensional magic-angle-spinning solid-state NMR. Biochemistry (2011) 1.57
Solid-state NMR investigation of the depth of insertion of protegrin-1 in lipid bilayers using paramagnetic Mn2+. Biophys J (2003) 1.55
Solid-state NMR investigations of peptide-lipid interaction and orientation of a beta-sheet antimicrobial peptide, protegrin. Biochemistry (2002) 1.54
Immobilization of the influenza A M2 transmembrane peptide in virus envelope-mimetic lipid membranes: a solid-state NMR investigation. Biochemistry (2009) 1.54
NMR detection of pH-dependent histidine-water proton exchange reveals the conduction mechanism of a transmembrane proton channel. J Am Chem Soc (2011) 1.53
Determination of the oligomeric number and intermolecular distances of membrane protein assemblies by anisotropic 1H-driven spin diffusion NMR spectroscopy. J Am Chem Soc (2006) 1.51
Side-chain conformation of the M2 transmembrane peptide proton channel of influenza a virus from 19F solid-state NMR. J Phys Chem B (2007) 1.50
Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I of cellulose synthase. Proc Natl Acad Sci U S A (2012) 1.41
BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential. Cancer Lett (2003) 1.38
Protonation, tautomerization, and rotameric structure of histidine: a comprehensive study by magic-angle-spinning solid-state NMR. J Am Chem Soc (2011) 1.37
Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. J Am Chem Soc (2011) 1.37
Shigella flexneri DegP facilitates IcsA surface expression and is required for efficient intercellular spread. Infect Immun (2002) 1.35
Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway. J Biol Chem (2008) 1.34
Conformational changes of an ion channel detected through water-protein interactions using solid-state NMR spectroscopy. J Am Chem Soc (2010) 1.33
The role of ubiquitination in Drosophila innate immunity. J Biol Chem (2005) 1.32
Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc (2011) 1.30
Membrane-dependent effects of a cytoplasmic helix on the structure and drug binding of the influenza virus M2 protein. J Am Chem Soc (2011) 1.29
Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus. J Am Chem Soc (2009) 1.28
Sensitivity-enhanced solid-state NMR detection of expansin's target in plant cell walls. Proc Natl Acad Sci U S A (2013) 1.28
Determination of peptide oligomerization in lipid bilayers using 19F spin diffusion NMR. J Am Chem Soc (2005) 1.26
The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4. Mol Pharmacol (2004) 1.22
Effects of guanidinium-phosphate hydrogen bonding on the membrane-bound structure and activity of an arginine-rich membrane peptide from solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2008) 1.19
Solid-state NMR investigation of the selective disruption of lipid membranes by protegrin-1. Biochemistry (2004) 1.18
Water-protein interactions of an arginine-rich membrane peptide in lipid bilayers investigated by solid-state nuclear magnetic resonance spectroscopy. J Phys Chem B (2010) 1.17
Conformational plasticity of the influenza A M2 transmembrane helix in lipid bilayers under varying pH, drug binding, and membrane thickness. Biochim Biophys Acta (2010) 1.16
Roles of arginine and lysine residues in the translocation of a cell-penetrating peptide from (13)C, (31)P, and (19)F solid-state NMR. Biochemistry (2009) 1.15
Immobilization and aggregation of the antimicrobial peptide protegrin-1 in lipid bilayers investigated by solid-state NMR. Biochemistry (2003) 1.14
Fluorine distribution in aquatic environment and its health effect in the Western Region of the Songnen Plain, Northeast China. Environ Monit Assess (2007) 1.13
Pectin-cellulose interactions in the Arabidopsis primary cell wall from two-dimensional magic-angle-spinning solid-state nuclear magnetic resonance. Biochemistry (2012) 1.11
Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR. Biochemistry (2010) 1.09
Intermolecular packing and alignment in an ordered beta-hairpin antimicrobial peptide aggregate from 2D solid-state NMR. J Am Chem Soc (2005) 1.09
Molecular epidemiology of coxsackievirus A16: intratype and prevalent intertype recombination identified. PLoS One (2013) 1.08
Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells. Am J Physiol Endocrinol Metab (2007) 1.07
Compensation for pulse imperfections in rotational-echo double-resonance NMR by composite pulses and EXORCYCLE. J Magn Reson (2004) 1.07
NMR determination of protein partitioning into membrane domains with different curvatures and application to the influenza M2 peptide. Biophys J (2012) 1.04
Asymmetric insertion of membrane proteins in lipid bilayers by solid-state NMR paramagnetic relaxation enhancement: a cell-penetrating Peptide example. J Am Chem Soc (2008) 1.03
pH-dependent conformation, dynamics, and aromatic interaction of the gating tryptophan residue of the influenza M2 proton channel from solid-state NMR. Biophys J (2013) 1.02
Modulation of melanogenesis by aloesin: a competitive inhibitor of tyrosinase. Pigment Cell Res (2002) 1.01
The membrane-bound structure and topology of a human α-defensin indicate a dimer pore mechanism for membrane disruption. Biochemistry (2010) 1.01
Arginine dynamics in a membrane-bound cationic beta-hairpin peptide from solid-state NMR. Chembiochem (2008) 1.01
Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1. Biochemistry (2004) 1.00
Structure and mechanism of beta-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy. Mol Biosyst (2009) 1.00
High-resolution orientation and depth of insertion of the voltage-sensing S4 helix of a potassium channel in lipid bilayers. J Mol Biol (2010) 0.99
TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells. Cancer Lett (2011) 0.98
Backbone and side chain assignment strategies for multiply labeled membrane peptides and proteins in the solid state. J Magn Reson (2003) 0.97
Effects of amantadine on the dynamics of membrane-bound influenza A M2 transmembrane peptide studied by NMR relaxation. J Biomol NMR (2009) 0.96
Dynamic structure of disulfide-removed linear analogs of tachyplesin-I in the lipid bilayer from solid-state NMR. Biochemistry (2007) 0.96
Conformational analysis of the full-length M2 protein of the influenza A virus using solid-state NMR. Protein Sci (2013) 0.94
Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy. J Am Chem Soc (2010) 0.93
Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR. J Am Chem Soc (2013) 0.92
Long-range 1H-19F distance measurement in peptides by solid-state NMR. J Am Chem Soc (2004) 0.92
Membrane-disruptive abilities of beta-hairpin antimicrobial peptides correlate with conformation and activity: a 31P and 1H NMR study. Biochim Biophys Acta (2005) 0.92
Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1. Oncol Rep (2013) 0.92
Orientation of a beta-hairpin antimicrobial peptide in lipid bilayers from two-dimensional dipolar chemical-shift correlation NMR. Biophys J (2006) 0.91
Determination of calpha chemical shift tensor orientation in peptides by dipolar-modulated chemical shift recoupling NMR spectroscopy. J Am Chem Soc (2002) 0.91
MHC class II transactivator (CIITA) expression is upregulated in multiple myeloma cells by IFN-gamma. Mol Immunol (2007) 0.91
Peptide-lipid interactions of the beta-hairpin antimicrobial peptide tachyplesin and its linear derivatives from solid-state NMR. Biochim Biophys Acta (2006) 0.91
Multidimensional solid-state NMR studies of the structure and dynamics of pectic polysaccharides in uniformly 13C-labeled Arabidopsis primary cell walls. Magn Reson Chem (2012) 0.91
Paramagnetic Cu(II) for probing membrane protein structure and function: inhibition mechanism of the influenza M2 proton channel. J Am Chem Soc (2012) 0.91
Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide from solid-state NMR. Biochim Biophys Acta (2008) 0.91
Structural and dynamics characterization of norovirus protease. Protein Sci (2013) 0.90
Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR. J Mol Biol (2010) 0.90
Reversible sheet-turn conformational change of a cell-penetrating peptide in lipid bilayers studied by solid-state NMR. J Mol Biol (2008) 0.89
Investigation of the dynamics of an elastin-mimetic polypeptide using solid-state NMR. Magn Reson Chem (2004) 0.89
Simultaneous extraction of multiple orientational constraints of membrane proteins by 13C-detected N-H dipolar couplings under magic angle spinning. J Magn Reson (2008) 0.89
Solid-state NMR spin diffusion for measurement of membrane-bound peptide structure: gramicidin A. Biochemistry (2004) 0.89
Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathway. Int J Oncol (2011) 0.89
Structures of β-hairpin antimicrobial protegrin peptides in lipopolysaccharide membranes: mechanism of gram selectivity obtained from solid-state nuclear magnetic resonance. Biochemistry (2011) 0.88
Membrane-dependent conformation, dynamics, and lipid interactions of the fusion peptide of the paramyxovirus PIV5 from solid-state NMR. J Mol Biol (2012) 0.87
Water-polysaccharide interactions in the primary cell wall of Arabidopsis thaliana from polarization transfer solid-state NMR. J Am Chem Soc (2014) 0.87
Isolation and characterization of a Chinese strain of human enterovirus 74 from a healthy child in the Tibet Autonomous Region of China. Arch Virol (2012) 0.87
Practical use of chemical shift databases for protein solid-state NMR: 2D chemical shift maps and amino-acid assignment with secondary-structure information. J Biomol NMR (2013) 0.87
2D 1H-31P solid-state NMR studies of the dependence of inter-bilayer water dynamics on lipid headgroup structure and membrane peptides. J Magn Reson (2008) 0.87
Large structure rearrangement of colicin ia channel domain after membrane binding from 2D 13C spin diffusion NMR. J Am Chem Soc (2005) 0.86
3D (13)C-(13)C-(13)C correlation NMR for de novo distance determination of solid proteins and application to a human alpha-defensin. J Magn Reson (2009) 0.86
Identification of amino acids essential for estrone-3-sulfate transport within transmembrane domain 2 of organic anion transporting polypeptide 1B1. PLoS One (2012) 0.86
Consequences of cytoplasmic irradiation: studies from microbeam. J Radiat Res (2009) 0.85
JC [corrected] virus detection in human tissue specimens. J Clin Pathol (2007) 0.85
Detection of the JC virus genome in lung cancers: possible role of the T-antigen in lung oncogenesis. Appl Immunohistochem Mol Morphol (2007) 0.85
Relaxation-compensated difference spin diffusion NMR for detecting 13C-13C long-range correlations in proteins and polysaccharides. J Biomol NMR (2014) 0.85
Conformational changes of colicin Ia channel-forming domain upon membrane binding: a solid-state NMR study. Biochim Biophys Acta (2002) 0.85
Fabrication of monodisperse porous zirconia microspheres and their phosphorylation for Friedel-Crafts alkylation of indoles. ACS Appl Mater Interfaces (2014) 0.85
Prophylactic effects of interleukin-2 receptor antagonists against graft-versus-host disease following unrelated donor peripheral blood stem cell transplantation. Biol Blood Marrow Transplant (2011) 0.84
A novel nitrite biosensor based on the direct electron transfer of hemoglobin immobilized on CdS hollow nanospheres. Biosens Bioelectron (2008) 0.84
Structure and dynamics of Brachypodium primary cell wall polysaccharides from two-dimensional (13)C solid-state nuclear magnetic resonance spectroscopy. Biochemistry (2014) 0.84
Conformational disorder of membrane peptides investigated from solid-state NMR line widths and line shapes. J Phys Chem B (2011) 0.84