Published in J Biol Chem on January 30, 2002
Transcriptome analysis and molecular signature of human retinal pigment epithelium. Hum Mol Genet (2010) 2.20
The association between statin use and age related maculopathy. Br J Ophthalmol (2003) 1.28
S156C mutation in tissue inhibitor of metalloproteinases-3 induces increased angiogenesis. J Biol Chem (2009) 1.08
[Pseudoxanthoma elasticum]. Ophthalmologe (2006) 0.92
Genetic variations and plasma levels of gelatinase A (matrix metalloproteinase-2) and gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy. Mol Vis (2008) 0.90
Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism. Apoptosis (2015) 0.87
Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics. Arthritis Res (2002) 0.87
Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice. PLoS One (2013) 0.80
A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression. Oncotarget (2014) 0.79
Clinical and biochemical effects of the E139K missense mutation in the TIMP3 gene, associated with Sorsby fundus dystrophy. Mol Vis (2009) 0.78
Looking into the future: Using induced pluripotent stem cells to build two and three dimensional ocular tissue for cell therapy and disease modeling. Brain Res (2015) 0.76
Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J Cell Sci (2002) 4.23
Translational control by the 3'-UTR: the ends specify the means. Trends Biochem Sci (2003) 4.00
The ADAMTS metalloproteinases. Biochem J (2005) 3.95
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest (2004) 3.63
Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol (2007) 3.28
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med (2003) 3.20
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. Cell (2004) 3.12
Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Cell (2003) 3.07
Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum (2004) 3.00
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem (2002) 2.94
A stress-responsive RNA switch regulates VEGFA expression. Nature (2008) 2.58
Cellular imaging in drug discovery. Nat Rev Drug Discov (2006) 2.52
The regulation of matrix metalloproteinases and their inhibitors. Int J Biochem Cell Biol (2007) 2.49
WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression. Mol Cell (2008) 2.34
TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol (2010) 2.17
The role of chondrocyte senescence in osteoarthritis. Aging Cell (2002) 2.06
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell (2012) 2.06
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy. Clin Cancer Res (2013) 2.00
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol (2008) 1.90
The GAIT system: a gatekeeper of inflammatory gene expression. Trends Biochem Sci (2009) 1.88
MMP-1 drives immunopathology in human tuberculosis and transgenic mice. J Clin Invest (2011) 1.77
Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3. Cardiovasc Res (2005) 1.77
DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. Mol Cell (2008) 1.70
Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs). J Cell Sci (2002) 1.69
Aminoacyl-tRNA synthetases in medicine and disease. EMBO Mol Med (2013) 1.67
Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis. Brain (2003) 1.67
Metalloproteinases and their inhibitors in tumor angiogenesis. Int J Cancer (2005) 1.63
A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity. EMBO J (2007) 1.59
Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A (2006) 1.59
Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion. Cancer Res (2008) 1.57
Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. Mol Cell Biol (2003) 1.53
Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells. Mol Cancer Res (2003) 1.50
Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. FEBS Lett (2004) 1.48
Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis Rheum (2006) 1.48
Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1. Am J Respir Crit Care Med (2005) 1.47
L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control. Mol Cell (2007) 1.47
Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma. Clin Cancer Res (2004) 1.46
Macromolecular complexes as depots for releasable regulatory proteins. Trends Biochem Sci (2007) 1.45
The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1. J Biol Chem (2003) 1.45
Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L. EMBO J (2011) 1.44
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC Dev Biol (2010) 1.44
A role for caveolae in cell migration. FASEB J (2004) 1.38
Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Res Ther (2005) 1.37
An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice. J Neurosci (2003) 1.34
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1). Implications for macular degenerations. J Biol Chem (2004) 1.32
Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis. J Immunol (2004) 1.32
Differential caveolin-1 polarization in endothelial cells during migration in two and three dimensions. Mol Biol Cell (2003) 1.31
Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology (2005) 1.31
Matrix metalloproteinases: protective roles in cancer. J Cell Mol Med (2011) 1.29
Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms. Breast Cancer Res (2009) 1.28
Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity. Mol Cell (2009) 1.27
TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol (2009) 1.24
Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score. Oncol Rep (2008) 1.24
Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma. Clin Cancer Res (2010) 1.22
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest (2013) 1.21
Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. J Biol Chem (2003) 1.21
Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer Res (2007) 1.21
Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein. J Immunol (2009) 1.20
Determinants of human B cell migration across brain endothelial cells. J Immunol (2003) 1.19
An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. FASEB J (2005) 1.18
Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo. Am J Pathol (2009) 1.17
GAPDH regulates cellular heme insertion into inducible nitric oxide synthase. Proc Natl Acad Sci U S A (2010) 1.17
Unexpected role of ceruloplasmin in intestinal iron absorption. Cell Metab (2005) 1.16
Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue. Eur J Oral Sci (2003) 1.16
Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12. Cancer Res (2006) 1.16
Spatial coordination of actin polymerization and ILK-Akt2 activity during endothelial cell migration. Dev Cell (2009) 1.14
Membrane microviscosity regulates endothelial cell motility. Nat Cell Biol (2002) 1.14
Regulation and dysregulation of 3'UTR-mediated translational control. Curr Opin Genet Dev (2013) 1.14
Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy. Proc Natl Acad Sci U S A (2008) 1.12
Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol (2012) 1.12
Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage. Am J Pathol (2009) 1.10
Role of ceruloplasmin in macrophage iron efflux during hypoxia. J Biol Chem (2003) 1.10
Clinical and genetic association of serum ceruloplasmin with cardiovascular risk. Arterioscler Thromb Vasc Biol (2011) 1.10
S156C mutation in tissue inhibitor of metalloproteinases-3 induces increased angiogenesis. J Biol Chem (2009) 1.08
Dynamic characterization of the molecular events during in vitro epidermal wound healing. J Invest Dermatol (2002) 1.08
Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets. Br J Pharmacol (2002) 1.08
Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages. Mol Cell Biol (2012) 1.07
Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism. Blood (2013) 1.06
IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production. EMBO J (2013) 1.06
Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control. Proc Natl Acad Sci U S A (2011) 1.06
Metalloproteinases and their inhibitors in angiogenesis. Expert Rev Mol Med (2003) 1.06
Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence. Clin Cancer Res (2013) 1.06
Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas. Carcinogenesis (2005) 1.06
Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks. J Immunol (2010) 1.05
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Mol Cancer Ther (2010) 1.05
Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Res (2006) 1.04
Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases. J Biol Chem (2001) 1.04
ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix related to the ADAMTS family of metalloproteases. Matrix Biol (2003) 1.04
Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. Glia (2007) 1.03
The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis. J Immunol (2011) 1.02
Increase in gelatinase-specificity of matrix metalloproteinase inhibitors correlates with antimetastatic efficacy in a T-cell lymphoma model. Cancer Res (2002) 1.02
Polarization of plasma membrane microviscosity during endothelial cell migration. Dev Cell (2004) 1.02
Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation. Mol Cell (2012) 1.01
VESGEN 2D: automated, user-interactive software for quantification and mapping of angiogenic and lymphangiogenic trees and networks. Anat Rec (Hoboken) (2009) 1.01