Published in J Biol Chem on January 30, 2002
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med (2007) 3.27
Recent insights into the biological roles of mucin-type O-glycosylation. Glycoconj J (2008) 1.53
Cancer vaccines and carbohydrate epitopes. Vaccine (2011) 1.40
Human airway mucin glycosylation: a combinatory of carbohydrate determinants which vary in cystic fibrosis. Glycoconj J (2001) 1.40
Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol (2009) 1.30
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells. Proc Natl Acad Sci U S A (2005) 1.19
Construction of a human glycogene library and comprehensive functional analysis. Glycoconj J (2004) 1.11
The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis. Infect Immun (2013) 1.07
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex. J Biol Chem (2009) 1.06
Mucin-type O-glycans and their roles in intestinal homeostasis. Glycobiology (2013) 0.98
Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2. Glycobiology (2012) 0.98
Tetrasulfated disaccharide unit in heparan sulfate: enzymatic formation and tissue distribution. J Biol Chem (2008) 0.89
Random glycopeptide bead libraries for seromic biomarker discovery. J Proteome Res (2010) 0.86
A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility. Proc Natl Acad Sci U S A (2014) 0.85
Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiation. J Biol Chem (2010) 0.82
Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis. Int J Cancer (2013) 0.82
Identification of mono- and disulfated N-acetyl-lactosaminyl Oligosaccharide structures as epitopes specifically recognized by humanized monoclonal antibody HMOCC-1 raised against ovarian cancer. J Biol Chem (2011) 0.82
Protein glycosylation in cancers and its potential therapeutic applications in neuroblastoma. J Hematol Oncol (2016) 0.80
Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans. Biochim Biophys Acta (2013) 0.79
Core saccharide dependence of sialyl Lewis X biosynthesis. Glycoconj J (2008) 0.78
Mucin-type O-glycosylation is critical for vascular integrity. Glycobiology (2014) 0.77
New Role of Nod Proteins in Regulation of Intestinal Goblet Cell Response in the Context of Innate Host Defense in an Enteric Parasite Infection. Infect Immun (2015) 0.76
Identification of a novel protein binding motif within the T-synthase for the molecular chaperone Cosmc. J Biol Chem (2014) 0.76
Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling). Biomolecules (2016) 0.75
Loss of intestinal O-glycans promotes spontaneous duodenal tumors. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res (2008) 20.59
The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature (2010) 10.04
PATRIC, the bacterial bioinformatics database and analysis resource. Nucleic Acids Res (2013) 7.63
Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci U S A (2008) 6.42
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nat Genet (2004) 4.95
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
PATRIC: the comprehensive bacterial bioinformatics resource with a focus on human pathogenic species. Infect Immun (2011) 4.57
Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science (2010) 4.52
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell (2007) 4.31
Leaf nitrogen and phosphorus stoichiometry across 753 terrestrial plant species in China. New Phytol (2005) 4.20
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol (2004) 3.85
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci U S A (2013) 3.53
Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats. J Pharmacol Exp Ther (2003) 3.48
Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation. Addiction (2010) 3.26
Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo. J Clin Invest (2006) 3.25
Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy. Circulation (2004) 3.12
Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China. Vet Microbiol (2013) 3.05
New variant of porcine epidemic diarrhea virus, United States, 2014. Emerg Infect Dis (2014) 2.99
Adaptive optics parallel spectral domain optical coherence tomography for imaging the living retina. Opt Express (2005) 2.97
Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS Biol (2007) 2.96
Suppression of renin-angiotensin gene expression in the kidney by paricalcitol. Kidney Int (2008) 2.95
CanPredict: a computational tool for predicting cancer-associated missense mutations. Nucleic Acids Res (2007) 2.86
MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol (2005) 2.85
KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc Natl Acad Sci U S A (2009) 2.84
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet (2010) 2.74
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study. Glycobiology (2007) 2.71
Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study. Radiology (2005) 2.69
Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes. J Biol Chem (2003) 2.66
Distinguishing cancer-associated missense mutations from common polymorphisms. Cancer Res (2007) 2.57
Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches. J Appl Physiol (1985) (2007) 2.52
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells. J Biol Chem (2007) 2.44
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation (2010) 2.35
The yak genome and adaptation to life at high altitude. Nat Genet (2012) 2.34
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052. Hepatology (2012) 2.29
Structure-function-folding relationship in a WW domain. Proc Natl Acad Sci U S A (2006) 2.28
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Sci Transl Med (2012) 2.27
Ultrahigh-resolution optical coherence tomography with monochromatic and chromatic aberration correction. Opt Express (2008) 2.26
Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. Proc Natl Acad Sci U S A (2005) 2.23
Nuclear accumulation of the Arabidopsis immune receptor RPS4 is necessary for triggering EDS1-dependent defense. Curr Biol (2007) 2.20
Peak early diastolic mitral annulus velocity by tissue Doppler imaging adds independent and incremental prognostic value. J Am Coll Cardiol (2003) 2.20
Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int (2010) 2.18
Development of an integrated wireless sensor network micro-environmental monitoring system. ISA Trans (2008) 2.16
Interface-induced superconductivity and strain-dependent spin density waves in FeSe/SrTiO3 thin films. Nat Mater (2013) 2.15
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination. Immunity (2011) 2.12
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev (2008) 2.12
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
Detection and genetic characterization of deltacoronavirus in pigs, Ohio, USA, 2014. Emerg Infect Dis (2014) 2.08
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci U S A (2008) 2.06
A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer Epidemiol Biomarkers Prev (2009) 2.04
A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging. J Am Coll Cardiol (2005) 2.03
Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity. Science (2006) 2.02
Fat deposition in dilated cardiomyopathy assessed by CMR. JACC Cardiovasc Imaging (2013) 2.00
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Presurgical nasoalveolar molding for cleft lip and palate: the application of digitally designed molds. Plast Reconstr Surg (2015) 1.93
Adaptive optics flood-illumination camera for high speed retinal imaging. Opt Express (2006) 1.92
Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. Proc Natl Acad Sci U S A (2014) 1.91
A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension (2011) 1.90
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab (2010) 1.89
MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. Nat Immunol (2010) 1.87
Measuring retinal contributions to the optical Stiles-Crawford effect with optical coherence tomography. Opt Express (2008) 1.87
Independent and incremental prognostic value of early mitral annulus velocity in patients with impaired left ventricular systolic function. J Am Coll Cardiol (2005) 1.85
Rapid turnover of effector-memory CD4(+) T cells in healthy humans. J Exp Med (2004) 1.85
Cone-beam CT for breast imaging: Radiation dose, breast coverage, and image quality. AJR Am J Roentgenol (2010) 1.83
Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells. Biochem Biophys Res Commun (2011) 1.82
Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation (2011) 1.81
Dynamics of the lakes in the middle and lower reaches of the Yangtze River basin, China, since late nineteenth century. Environ Monit Assess (2012) 1.80
Yeast frataxin solution structure, iron binding, and ferrochelatase interaction. Biochemistry (2004) 1.80
On the Euclidean distance of images. IEEE Trans Pattern Anal Mach Intell (2005) 1.80
Research on an Mg-Zn alloy as a degradable biomaterial. Acta Biomater (2009) 1.80
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
Quantum dot imaging for embryonic stem cells. BMC Biotechnol (2007) 1.78
Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood (2010) 1.78
Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care (2013) 1.77
A facile and highly atom-economic approach to biaryl-containing medium-ring bislactones. Chem Commun (Camb) (2011) 1.77
Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United States. Vet Microbiol (2009) 1.77
Relationships between cigarette consumption and biomarkers of tobacco toxin exposure. Cancer Epidemiol Biomarkers Prev (2005) 1.76
Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics. Proc Natl Acad Sci U S A (2011) 1.76
Alternative O-GlcNAcylation/O-phosphorylation of Ser16 induce different conformational disturbances to the N terminus of murine estrogen receptor beta. Chem Biol (2006) 1.74
Reduction of B cell turnover in chronic lymphocytic leukaemia. Br J Haematol (2008) 1.74
How human location-specific contact patterns impact spatial transmission between populations? Sci Rep (2013) 1.74
Evaluation of carcinogen exposure in people who used "reduced exposure" tobacco products. J Natl Cancer Inst (2004) 1.74
Aldosterone receptor antagonism induces reverse remodeling when added to angiotensin receptor blockade in chronic heart failure. J Am Coll Cardiol (2007) 1.73
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proc Natl Acad Sci U S A (2008) 1.69
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. J Am Chem Soc (2013) 1.69
A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet (2011) 1.68
Emergence and transmission pathways of rapidly evolving evolutionary branch C4a strains of human enterovirus 71 in the Central Plain of China. PLoS One (2011) 1.67
Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction. Biochem Biophys Res Commun (2007) 1.66
Decompressive hemicraniectomy in malignant middle cerebral artery infarct: a randomized controlled trial enrolling patients up to 80 years old. Neurocrit Care (2012) 1.65
Noroviruses distinguish between type 1 and type 2 histo-blood group antigens for binding. J Virol (2008) 1.65
Molecular analysis of the pathophysiological binding of the platelet aggregation-inducing factor podoplanin to the C-type lectin-like receptor CLEC-2. Cancer Sci (2007) 1.64
Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth. Breast Cancer Res (2011) 1.64
Evolution of scaling emergence in large-scale spatial epidemic spreading. PLoS One (2011) 1.64
Pathology of US porcine epidemic diarrhea virus strain PC21A in gnotobiotic pigs. Emerg Infect Dis (2014) 1.62
Measurement and modeling of human T cell kinetics. Eur J Immunol (2003) 1.61
Deep mRNA sequencing for in vivo functional analysis of cardiac transcriptional regulators: application to Galphaq. Circ Res (2010) 1.61
NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney Int (2013) 1.61
The transcription factor DksA prevents conflicts between DNA replication and transcription machinery. Cell (2010) 1.60