Published in Cell Stem Cell on November 20, 2007
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The p53 tumor suppressor protein regulates hematopoietic stem cell fate. J Cell Physiol (2011) 1.08
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p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging. Stem Cell Reports (2014) 0.89
The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells. Mol Cell Biol (2011) 0.88
Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis. PLoS One (2014) 0.88
Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells. Stem Cells (2012) 0.88
Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program. EMBO J (2015) 0.87
SP/drug efflux functionality of hematopoietic progenitors is controlled by mesenchymal niche through VLA-4/CD44 axis. Leukemia (2013) 0.87
The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells. Leukemia (2011) 0.87
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The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment. Cell Adh Migr (2014) 0.87
Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3. Int J Hematol (2014) 0.86
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Niche competition and cancer metastasis to bone. J Clin Invest (2011) 0.85
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Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell (2004) 12.67
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med (2006) 7.62
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature (2004) 7.21
Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell (2007) 5.94
Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell (2010) 4.90
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. Cell Metab (2006) 4.33
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res (2005) 4.25
Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. J Exp Med (2009) 4.03
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med (2005) 4.02
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med (2006) 3.78
PML targeting eradicates quiescent leukaemia-initiating cells. Nature (2008) 3.75
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med (2012) 3.33
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol (2002) 3.08
Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Cell Stem Cell (2011) 3.05
Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell (2008) 2.69
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med (2009) 2.66
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem (2003) 2.59
p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell (2011) 2.58
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell (2013) 2.58
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature (2010) 2.47
Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. Cell (2012) 2.36
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med (2009) 2.29
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood (2004) 2.27
Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol (2003) 2.24
Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ Res (2007) 2.22
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev (2005) 2.18
Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest. Cell Stem Cell (2008) 2.14
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. Dev Biol (2004) 2.13
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab (2009) 2.13
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev (2008) 2.12
The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage. Development (2006) 2.07
Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity. Science (2006) 2.02
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VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment. Arterioscler Thromb Vasc Biol (2008) 1.90
Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment. J Infect Dis (2007) 1.85
Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization. J Exp Med (2011) 1.79
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Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood (2010) 1.78
Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche. Ann N Y Acad Sci (2007) 1.78
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Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J (2005) 1.77
Allelic and non-allelic heterogeneities in pyridoxine dependent seizures revealed by ALDH7A1 mutational analysis. Mol Genet Metab (2007) 1.75
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Blood (2005) 1.75
RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis. Nat Med (2011) 1.71
Angiopoietin-1 promotes lymphatic sprouting and hyperplasia. Blood (2005) 1.71
Hematopoietic stem cells and their niche. Trends Immunol (2005) 1.70
Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci (2013) 1.70
Design of efficient thermally activated delayed fluorescence materials for pure blue organic light emitting diodes. J Am Chem Soc (2012) 1.68
HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis. Proc Natl Acad Sci U S A (2013) 1.67
Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction. Biochem Biophys Res Commun (2007) 1.66
The RNA-binding protein HuD regulates neuronal cell identity and maturation. Proc Natl Acad Sci U S A (2005) 1.66
Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation. J Exp Med (2002) 1.63
Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J Immunol (2007) 1.62
Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med (2005) 1.61
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med (2010) 1.59