PubRank

Akinori Kimura

Author PubWeight™ 130.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell 2002 4.72
2 Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. J Exp Med 2004 2.99
3 A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell 2010 2.27
4 Alpha B-crystallin mutation in dilated cardiomyopathy. Biochem Biophys Res Commun 2006 2.27
5 Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations. J Hum Genet 2008 1.94
6 Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol 2010 1.88
7 Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes. Hum Mutat 2011 1.85
8 Lifelong left ventricular remodeling of hypertrophic cardiomyopathy caused by a founder frameshift deletion mutation in the cardiac Myosin-binding protein C gene among Japanese. J Am Coll Cardiol 2005 1.80
9 Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy. J Am Coll Cardiol 2004 1.79
10 Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia. J Biol Chem 2004 1.75
11 Electrocardiographic characteristics and SCN5A mutations in idiopathic ventricular fibrillation associated with early repolarization. Circ Arrhythm Electrophysiol 2011 1.74
12 Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res 2007 1.74
13 Titin mutations as the molecular basis for dilated cardiomyopathy. Biochem Biophys Res Commun 2002 1.70
14 Prevalence and distribution of sarcomeric gene mutations in Japanese patients with familial hypertrophic cardiomyopathy. Circ J 2011 1.64
15 Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation 2007 1.57
16 Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5. Circ J 2012 1.52
17 Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis. Circ Cardiovasc Genet 2013 1.47
18 Dilated cardiomyopathy-associated FHOD3 variant impairs the ability to induce activation of transcription factor serum response factor. Circ J 2013 1.47
19 High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet 2007 1.44
20 Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy. Biochem Biophys Res Commun 2004 1.39
21 Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy. J Am Coll Cardiol 2009 1.38
22 Novel calmodulin mutations associated with congenital arrhythmia susceptibility. Circ Cardiovasc Genet 2014 1.27
23 A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C. J Biol Chem 2003 1.23
24 ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene. J Am Coll Cardiol 2009 1.22
25 E-selectin polymorphism associated with myocardial infarction causes enhanced leukocyte-endothelial interactions under flow conditions. Arterioscler Thromb Vasc Biol 2003 1.20
26 Structural analysis of obscurin gene in hypertrophic cardiomyopathy. Biochem Biophys Res Commun 2007 1.19
27 Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy. J Muscle Res Cell Motil 2005 1.16
28 Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. Cardiovasc Res 2009 1.12
29 Association of Takayasu arteritis with HLA-B 67:01 and two amino acids in HLA-B protein. Rheumatology (Oxford) 2013 1.12
30 Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Am J Hum Genet 2002 1.11
31 Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations. Hum Mol Genet 2012 1.10
32 A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease. Cardiovasc Res 2002 1.06
33 Copy number variations of CCL3L1 and long-term prognosis of HIV-1 infection in asymptomatic HIV-infected Japanese with hemophilia. Immunogenetics 2007 1.03
34 Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol 2013 1.02
35 A novel disease gene for Brugada syndrome: sarcolemmal membrane-associated protein gene mutations impair intracellular trafficking of hNav1.5. Circ Arrhythm Electrophysiol 2012 1.02
36 Diversity of MHC class I genes in Burmese-origin rhesus macaques. Immunogenetics 2010 1.01
37 Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease. Hum Genet 2007 1.00
38 Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis. Immunogenetics 2006 1.00
39 Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS model. J Virol 2005 0.98
40 Truncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect. FEBS Lett 2004 0.97
41 Role of HCN4 channel in preventing ventricular arrhythmia. J Hum Genet 2009 0.97
42 Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia. Exp Hematol 2007 0.96
43 Natural selection in the TLR-related genes in the course of primate evolution. Immunogenetics 2008 0.95
44 Apelin is a positive regulator of ACE2 in failing hearts. J Clin Invest 2013 0.95
45 Reference strand-mediated conformation analysis-based typing of multiple alleles in the rhesus macaque MHC class I Mamu-A and Mamu-B loci. Electrophoresis 2007 0.94
46 HLA-DPB1*0202 is associated with a predictor of good prognosis of Graves' disease in the Japanese. Hum Immunol 2006 0.94
47 Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction. Circ Arrhythm Electrophysiol 2012 0.94
48 Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages. Hypertens Res 2010 0.93
49 Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy. Biochem Biophys Res Commun 2007 0.93
50 Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative. Matrix Biol 2007 0.92
51 Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice. EMBO J 2012 0.92
52 Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Am J Hum Genet 2013 0.91
53 The role of a common TNNT2 polymorphism in cardiac hypertrophy. J Hum Genet 2004 0.91
54 Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy. Circ J 2008 0.90
55 Protection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV. PLoS One 2010 0.90
56 Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in burmese rhesus macaques. J Virol 2012 0.89
57 Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1. J Biol Chem 2010 0.88
58 Impact of novel TRIM5alpha variants, Gly110Arg and G176del, on the anti-HIV-1 activity and the susceptibility to HIV-1 infection. AIDS 2009 0.88
59 TIM1 haplotype may control the disease progression to AIDS in a HIV-1-infected female cohort in Thailand. AIDS 2010 0.88
60 Association study of CD14 polymorphism with myocardial infarction in a Japanese population. Jpn Heart J 2003 0.87
61 A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection. AIDS Res Hum Retroviruses 2013 0.87
62 Control of simian immunodeficiency virus replication by vaccine-induced Gag- and Vif-specific CD8+ T cells. J Virol 2013 0.87
63 A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome. J Cardiovasc Electrophysiol 2007 0.86
64 Impact of vaccination on cytotoxic T lymphocyte immunodominance and cooperation against simian immunodeficiency virus replication in rhesus macaques. J Virol 2011 0.86
65 Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope. AIDS 2008 0.86
66 Diversity of MHC class I haplotypes in cynomolgus macaques. Immunogenetics 2011 0.85
67 Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue. Basic Res Cardiol 2013 0.85
68 A DFNA5 mutation identified in Japanese families with autosomal dominant hereditary hearing loss. Ann Hum Genet 2014 0.85
69 Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy. Am J Physiol Heart Circ Physiol 2007 0.85
70 HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis. J Hum Genet 2009 0.85
71 A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques. PLoS One 2013 0.84
72 No evidence of an association between the APOBEC3B deletion polymorphism and susceptibility to HIV infection and AIDS in Japanese and Indian populations. J Infect Dis 2010 0.84
73 Anti-KCNH2 antibody-induced long QT syndrome: novel acquired form of long QT syndrome. J Am Coll Cardiol 2007 0.84
74 Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access. Mol Pharmacol 2004 0.83
75 Susceptibility to chronic thromboembolic pulmonary hypertension may be conferred by miR-759 via its targeted interaction with polymorphic fibrinogen alpha gene. Hum Genet 2010 0.83
76 Toll-like receptor 2 gene polymorphisms associated with aggressive periodontitis in Japanese. Open Dent J 2011 0.83
77 Spontaneous T wave alternans in a patient with Brugada syndrome--responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing. J Cardiovasc Electrophysiol 2005 0.83
78 Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations. Cardiovasc Res 2013 0.83
79 Limited impact of passive non-neutralizing antibody immunization in acute SIV infection on viremia control in rhesus macaques. PLoS One 2013 0.82
80 A ZASP missense mutation, S196L, leads to cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy. Circ Arrhythm Electrophysiol 2010 0.82
81 Validation of the association between AGTRL1 polymorphism and coronary artery disease in the Japanese and Korean populations. J Hum Genet 2009 0.82
82 High-resolution mapping for essential hypertension using microsatellite markers. Hypertension 2007 0.82
83 High-contrast fluorescence imaging of tumors in vivo using nanoparticles of amphiphilic brush-like copolymers produced by ROMP. Angew Chem Int Ed Engl 2011 0.82
84 APOBEC3H polymorphisms associated with the susceptibility to HIV-1 infection and AIDS progression in Japanese. Immunogenetics 2015 0.82
85 HLA and CTLA4 polymorphisms may confer a synergistic risk in the susceptibility to Graves' disease. J Hum Genet 2010 0.82
86 Validation of eight genetic risk factors in East Asian populations replicated the association of BRAP with coronary artery disease. J Hum Genet 2009 0.81
87 HLA-B polymorphism in Japanese HIV-1-infected long-term surviving hemophiliacs. Viral Immunol 2005 0.81
88 Lineage-specific evolution of T-cell immunoglobulin and mucin domain 1 gene in the primates. Immunogenetics 2012 0.81
89 Improvement of left ventricular dysfunction and of survival prognosis of dilated cardiomyopathy by administration of calcium sensitizer SCH00013 in a mouse model. J Am Coll Cardiol 2010 0.81
90 Genetic screening and double mutation in Japanese patients with hypertrophic cardiomyopathy. Circ J 2011 0.81
91 Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques. Immunogenetics 2011 0.81
92 A single nucleotide polymorphism in the 3'-untranslated region of MyD88 gene is associated with Buerger disease but not with Takayasu arteritis in Japanese. J Hum Genet 2011 0.81
93 Replication studies for the association of PSMA6 polymorphism with coronary artery disease in East Asian populations. J Hum Genet 2009 0.81
94 Status of TIM-1 exon 4 haplotypes and CD4+T cell counts in HIV-1 seroprevalent North Indians. Hum Immunol 2012 0.80
95 Clinical and genetic characteristics of GAD-antibody positive patients initially diagnosed as having type 2 diabetes. Diabetes Res Clin Pract 2004 0.80
96 A frameshift deletion mutation in the cardiac myosin-binding protein C gene associated with dilated phase of hypertrophic cardiomyopathy and dilated cardiomyopathy. J Cardiol 2010 0.80
97 A mutation in Wolfram syndrome type 1 gene in a Japanese family with autosomal dominant low-frequency sensorineural hearing loss. Acta Otolaryngol 2005 0.80
98 Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome. J Biol Chem 2009 0.80
99 Direct determination of single nucleotide polymorphism haplotype of NFKBIL1 promoter polymorphism by DNA conformation analysis and its application to association study of chronic inflammatory diseases. Hum Immunol 2006 0.80
100 Analysis of the major epitope of the alpha2 chain of bovine type I collagen in children with bovine gelatin allergy. J Allergy Clin Immunol 2002 0.80
101 Dilated phase of hypertrophic cardiomyopathy caused by two different sarcomere mutations, treated with surgical left ventricular reconstruction and cardiac resynchronization therapy with a defibrillator. Intern Med 2012 0.79
102 Human cardiac ryanodine receptor mutations in ion channel disorders in Japan. Int J Cardiol 2006 0.79
103 A novel link of HLA locus to the regulation of immunity and infection: NFKBIL1 regulates alternative splicing of human immune-related genes and influenza virus M gene. J Autoimmun 2013 0.79
104 Gender ratio distortion in abortuses and live births from patients with recurrent spontaneous abortion. Am J Reprod Immunol 2009 0.79
105 ULBP4/RAET1E is highly polymorphic in the Old World monkey. Immunogenetics 2011 0.79
106 Vaccine-based, long-term, stable control of simian/human immunodeficiency virus 89.6PD replication in rhesus macaques. J Gen Virol 2007 0.78
107 A novel de novo mutation of β-cardiac myosin heavy chain gene found in a twelve-year-old boy with hypertrophic cardiomyopathy. J Genet 2014 0.78
108 A novel mutation in FKBP12.6 binding region of the human cardiac ryanodine receptor gene (R2401H) in a Japanese patient with catecholaminergic polymorphic ventricular tachycardia. Int J Cardiol 2005 0.78
109 Novel C-terminus frameshift mutation, 1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift cause accelerated inactivation. J Mol Cell Cardiol 2004 0.78
110 The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts. Age (Dordr) 2013 0.78
111 Successful outcome in a pregnant woman with isolated noncompaction of the left ventricular myocardium. Intern Med 2007 0.78
112 Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease. Hum Genet 2009 0.78
113 Genomic structure and eight novel exonic polymorphisms of the human N-cadherin gene. J Hum Genet 2002 0.78
114 Clinical significance of T-wave alternans in hypertrophic cardiomyopathy. Circ J 2002 0.78
115 Molecular evolution of immunoglobulin superfamily genes in primates. Immunogenetics 2011 0.77
116 Clinical characteristics and risk of arrhythmia recurrences in patients with idiopathic ventricular fibrillation associated with early repolarization. Int J Cardiol 2012 0.77
117 Multistimuli-responsive azobenzene nanofibers with aggregation-induced emission enhancement characteristics. Chem Commun (Camb) 2014 0.77
118 Dominant induction of vaccine antigen-specific cytotoxic T lymphocyte responses after simian immunodeficiency virus challenge. Biochem Biophys Res Commun 2011 0.77
119 Long-term outcome of 4 Korean families with hypertrophic cardiomyopathy caused by 4 different mutations. Clin Cardiol 2010 0.77
120 Association of HLA-A*02:06 and HLA-DRB1*04:05 with clinical subtypes of juvenile idiopathic arthritis. J Hum Genet 2010 0.77
121 Genetic factors that confer sensitivity to HAART in HIV-infected subjects: implication of a benefit of an earlier initiation of HAART. Pharmacogenomics 2008 0.76
122 Complex divergence at a microsatellite marker C1_2_5 in the lineage of HLA-Cw/-B haplotype. J Hum Genet 2009 0.76
123 Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy. Am J Reprod Immunol 2007 0.76
124 Major histocompatibility complex class I-restricted cytotoxic T lymphocyte responses during primary simian immunodeficiency virus infection in Burmese rhesus macaques. Microbiol Immunol 2011 0.76
125 Does a gene polymorphism predisposing to an intermediate phenotype predict the risk of disease? A lesson from CETP, high-density lipoprotein-cholesterol and coronary heart disease. Circ J 2009 0.75
126 A novel protein found in the I bands of myofibrils is produced by alternative splicing of the DLST gene. Biochim Biophys Acta 2009 0.75
127 17-year follow-up study of a patient with obstructive hypertrophic cardiomyopathy with a deletion mutation in the cardiac myosin binding protein C gene. Circ J 2004 0.75
128 [Genetic factors for coronary artery disease]. Nihon Rinsho 2016 0.75
129 Divergence and diversity of ULBP2 genes in rhesus and cynomolgus macaques. Immunogenetics 2014 0.75
130 Hypertrophic Cardiomyopathy Accompanied by Spinocerebellar Atrophy With a Novel Mutation in Troponin I Gene. Int Heart J 2016 0.75
131 Influence of side chain length on fluorescence intensity of ROMP-based polymeric nanoparticles and their tumor specificity in in-vivo tumor imaging. Small 2011 0.75