Published in N Engl J Med on February 21, 2002
Investigation of the Gut Microbiota in Regulating Nutrient Absorption in Humans | NCT02037295
The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring) (2006) 8.25
Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: a randomized trial. JAMA (2010) 5.77
Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections. Arch Pathol Lab Med (2010) 3.91
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery. Surg Obes Relat Dis (2007) 3.67
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 3.62
PPAR delta: a dagger in the heart of the metabolic syndrome. J Clin Invest (2006) 3.17
Treatment of obesity in primary care practice in the United States: a systematic review. J Gen Intern Med (2009) 2.89
Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. Int J Obes (Lond) (2011) 2.39
Behavioral treatment of obesity. Psychiatr Clin North Am (2011) 2.03
Social network concordance in food choice among spouses, friends, and siblings. Am J Public Health (2011) 1.49
Energy regulatory signals and food reward. Pharmacol Biochem Behav (2010) 1.25
Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli. Int J Obes (Lond) (2013) 1.24
Quality of cardiovascular disease preventive care and physician/practice characteristics. J Gen Intern Med (2006) 1.19
Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes. Histochem Cell Biol (2006) 1.11
Less activation in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal in obese than in lean women and its association with successful weight loss. Am J Clin Nutr (2007) 1.10
Diagnosis and management of binge eating disorder. World Psychiatry (2007) 1.07
Application of Response Surface Methodology (RSM) for Optimization of Anti-Obesity Effect in Fermented Milk by Lactobacillus plantarum Q180. Korean J Food Sci Anim Resour (2014) 1.05
The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors. Mol Cell Biol (2009) 1.05
Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats. Br J Pharmacol (2006) 1.02
The role of leptin in the control of insulin-glucose axis. Front Neurosci (2013) 1.00
Regulatable fatty acid transport mechanisms are central to the pathophysiology of obesity, fatty liver, and metabolic syndrome. Hepatology (2008) 0.97
Disruption of KATP channel expression in skeletal muscle by targeted oligonucleotide delivery promotes activity-linked thermogenesis. Mol Ther (2015) 0.95
A new look at the science of weight control: how acceptance and commitment strategies can address the challenge of self-regulation. Appetite (2014) 0.95
Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells. Biochim Biophys Acta (2010) 0.94
Anti-obesity effects of Lysimachia foenum-graecum characterized by decreased adipogenesis and regulated lipid metabolism. Exp Mol Med (2011) 0.92
The effect of a low-carbohydrate diet on the nonalcoholic fatty liver in morbidly obese patients before bariatric surgery. Surg Endosc (2007) 0.92
Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias. CMAJ (2002) 0.90
Increased hepatocellular uptake of long chain fatty acids occurs by different mechanisms in fatty livers due to obesity or excess ethanol use, contributing to development of steatohepatitis in both settings. Trans Am Clin Climatol Assoc (2005) 0.89
The gut hormones in appetite regulation. J Obes (2011) 0.88
Automating assessment of lifestyle counseling in electronic health records. Am J Prev Med (2014) 0.88
Inhibition of adipogenesis by Tempol in 3T3-L1 cells. Free Radic Biol Med (2010) 0.87
Polycystic ovary syndrome: current status and future perspective. Front Biosci (Elite Ed) (2014) 0.86
Learning curve for laparoscopic sleeve gastrectomy: role of training in a high-volume bariatric center. Surg Endosc (2015) 0.86
Evidence of Insulin Resistance and Other Metabolic Alterations in Boys with Duchenne or Becker Muscular Dystrophy. Int J Endocrinol (2015) 0.85
Obesity and its therapy: from genes to community action. Pediatr Clin North Am (2006) 0.85
Body mass index relates to males with posttraumatic stress disorder. J Natl Med Assoc (2006) 0.84
Ischemic colitis after mesotherapy combined with anti-obesity medications. World J Gastroenterol (2010) 0.83
A natural diet versus modern Western diets? A new approach to prevent "well-being syndromes". Dig Dis Sci (2005) 0.83
Pharmacotherapy for childhood obesity: present and future prospects. Int J Obes (Lond) (2012) 0.83
Orlistat reverse fatty infiltration and improves hepatic fibrosis in obese patients with nonalcoholic steatohepatitis (NASH). Dig Dis Sci (2007) 0.83
IMPACT: a multi-level family and school intervention targeting obesity in urban youth. Contemp Clin Trials (2013) 0.83
Effect of Gambisan on the Inhibition of Adipogenesis in 3T3-L1 Adipocytes. Evid Based Complement Alternat Med (2013) 0.82
Peripheral mechanisms in the control of appetite and related experimental therapies in obesity. Regul Pept (2009) 0.81
Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice. Eur J Nutr (2010) 0.81
Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities. Toxicol Pathol (2012) 0.81
Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1. J Cell Mol Med (2015) 0.80
Sleep study, respiratory mechanics, chemosensitive response and quality of life in morbidly obese patients undergoing bariatric surgery: a prospective, randomized, controlled trial. BMC Surg (2011) 0.80
Metabolic syndrome in the Mediterranean region: Current status. Indian J Endocrinol Metab (2012) 0.80
The Challenges and Opportunities Associated with Reimbursement for Obesity Pharmacotherapy in the USA. Pharmacoeconomics (2015) 0.79
Adherence to an overweight and obesity treatment: how to motivate a patient? PeerJ (2014) 0.79
Weight loss at first postoperative visit predicts long-term outcome of Roux-en-Y gastric bypass using Duke weight loss surgery chart. Surg Obes Relat Dis (2012) 0.79
Significant weight loss after laparoscopic Nissen fundoplication. Surg Endosc (2004) 0.79
Effects of chemosignals from sad tears and postprandial plasma on appetite and food intake in humans. PLoS One (2012) 0.77
Obesity pharmacotherapy: current perspectives and future directions. Curr Cardiol Rev (2013) 0.77
All-Cause and Cause-Specific Mortality Associated with Bariatric Surgery: A Review. Curr Atheroscler Rep (2015) 0.77
A Trypsin Inhibitor from Tamarind Reduces Food Intake and Improves Inflammatory Status in Rats with Metabolic Syndrome Regardless of Weight Loss. Nutrients (2016) 0.75
Conceptual basis and clinical rationale for the development of a multidisciplinary weight management center. Int J Obes Suppl (2012) 0.75
Combined aerobic and resistance exercise is effective for achieving weight loss and reducing cardiovascular risk factors without deteriorating bone health in obese young adults. Ann Pediatr Endocrinol Metab (2013) 0.75
Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity. World J Diabetes (2016) 0.75
Cardiovascular events in patients with obesity: an observational study. Br J Gen Pract (2010) 0.75
Low serum 25(OH)D levels are assocıated to hıgher BMI and metabolic syndrome parameters in adult subjects in Turkey. Afr Health Sci (2015) 0.75
Exposure to sibutramine during pregnancy. Can Fam Physician (2007) 0.75
Pharmacotherapy for obesity. N Engl J Med (2002) 0.75
Diet and physical activity behavior among users of prescription weight loss medications. Int J Behav Nutr Phys Act (2004) 0.75
Pharmacotherapy for obesity. N Engl J Med (2002) 0.75
Influence of intense multidisciplinary follow-up and orlistat on weight reduction in a primary care setting. BMC Fam Pract (2005) 0.75
Pharmacotherapy for obesity. N Engl J Med (2002) 0.75
Switching harmful visceral fat to beneficial energy combustion improves metabolic dysfunctions. JCI Insight (2017) 0.75
Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med (2008) 5.34
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology (2004) 3.61
High adiposity and high body mass index-for-age in US children and adolescents overall and by race-ethnic group. Am J Clin Nutr (2010) 3.22
The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults. J Clin Endocrinol Metab (2004) 3.13
Brain-derived neurotrophic factor and obesity in the WAGR syndrome. N Engl J Med (2008) 2.91
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes (2006) 2.87
Eating-disordered behaviors, body fat, and psychopathology in overweight and normal-weight children. J Consult Clin Psychol (2004) 2.37
A prospective study of psychological predictors of body fat gain among children at high risk for adult obesity. Pediatrics (2006) 2.28
Orthopedic complications of overweight in children and adolescents. Pediatrics (2006) 2.25
A prospective study of loss of control eating for body weight gain in children at high risk for adult obesity. Int J Eat Disord (2009) 1.93
Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab (2004) 1.92
Obesity prevalence in the United States--up, down, or sideways? N Engl J Med (2011) 1.91
A prospective study of pediatric loss of control eating and psychological outcomes. J Abnorm Psychol (2011) 1.89
The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am J Clin Nutr (2009) 1.88
Assessing weight-related quality of life in adolescents. Obesity (Silver Spring) (2006) 1.85
The perceived onset of dieting and loss of control eating behaviors in overweight children. Int J Eat Disord (2005) 1.78
Obesity-related hypoferremia is not explained by differences in reported intake of heme and nonheme iron or intake of dietary factors that can affect iron absorption. J Am Diet Assoc (2008) 1.77
Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency. J Clin Endocrinol Metab (2004) 1.73
A multisite investigation of binge eating behaviors in children and adolescents. J Consult Clin Psychol (2007) 1.72
Loss of control over eating, adiposity, and psychopathology in overweight children. Int J Eat Disord (2002) 1.71
Indices of insulin action, disposal, and secretion derived from fasting samples and clamps in normal glucose-tolerant black and white children. Diabetes Care (2002) 1.68
Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development. Clin Endocrinol (Oxf) (2008) 1.67
Laboratory assessment of the food intake of children and adolescents with loss of control eating. Am J Clin Nutr (2009) 1.64
Binge eating in overweight treatment-seeking adolescents. J Pediatr Psychol (2006) 1.64
Health-related quality of life in overweight and nonoverweight black and white adolescents. J Pediatr (2005) 1.60
Insulin resistance, hyperinsulinemia, and energy intake in overweight children. J Pediatr (2008) 1.59
Psychological status and weight-related distress in overweight or at-risk-for-overweight children. Obesity (Silver Spring) (2006) 1.58
Longitudinal study of the diagnosis of components of the metabolic syndrome in individuals with binge-eating disorder. Am J Clin Nutr (2010) 1.58
Salience of loss of control for pediatric binge episodes: does size really matter? Int J Eat Disord (2010) 1.53
The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Clin Endocrinol (Oxf) (2006) 1.50
Self-assessment of pubertal stage in overweight children. Pediatrics (2002) 1.48
Disordered-eating attitudes in relation to bone mineral density and markers of bone turnover in overweight adolescents. J Adolesc Health (2009) 1.42
Hormonal responses and test meal intake among obese teenagers before and after laparoscopic adjustable gastric banding. Am J Clin Nutr (2013) 1.41
Which metric of relative weight best captures body fatness in children? Obes Res (2003) 1.39
Sex differences in visceral adipose tissue volume among African Americans. Am J Clin Nutr (2002) 1.35
Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions. Obes Res (2002) 1.34
Effects of binge eating on satiation, satiety, and energy intake of overweight children. Am J Clin Nutr (2006) 1.30
Influence of excess adiposity on exercise fitness and performance in overweight children and adolescents. Pediatrics (2005) 1.29
Comparison of assessments of children's eating-disordered behaviors by interview and questionnaire. Int J Eat Disord (2003) 1.29
Loss of control eating disorder in children age 12 years and younger: proposed research criteria. Eat Behav (2008) 1.25
The stability of metabolic syndrome in children and adolescents. J Clin Endocrinol Metab (2009) 1.23
Pediatric obesity: etiology and treatment. Endocrinol Metab Clin North Am (2009) 1.22
Challenges and opportunities of defining clinical leptin resistance. Cell Metab (2012) 1.21
Eating in the absence of hunger in adolescents: intake after a large-array meal compared with that after a standardized meal. Am J Clin Nutr (2010) 1.21
Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity. Diabetes (2005) 1.21
Validation of the emotional eating scale adapted for use in children and adolescents (EES-C). Int J Eat Disord (2007) 1.21
Psychometric properties of a new questionnaire to assess eating in the absence of hunger in children and adolescents. Appetite (2008) 1.19
Influence of serum leptin on weight and body fat growth in children at high risk for adult obesity. J Clin Endocrinol Metab (2006) 1.16
Diet and sex hormones in girls: findings from a randomized controlled clinical trial. J Natl Cancer Inst (2003) 1.15
Serum brain-derived neurotrophic factor concentrations in lean and overweight children and adolescents. J Clin Endocrinol Metab (2006) 1.14
Children's descriptions of the foods consumed during loss of control eating episodes. Eat Behav (2006) 1.14
Adiposity and human regional body temperature. Am J Clin Nutr (2009) 1.12
Comparison of methods to assess change in children's body composition. Am J Clin Nutr (2004) 1.11
Patients with Bardet-Biedl syndrome have hyperleptinemia suggestive of leptin resistance. J Clin Endocrinol Metab (2011) 1.10
Validation of three food frequency questionnaires to assess dietary calcium intake in adults. J Am Diet Assoc (2007) 1.10
Prevalence of overweight among inner city Hispanic-American children and adolescents. Obes Res (2004) 1.09
Calcium intake and adiposity. Am J Clin Nutr (2003) 1.04
Comparison of the child and parent forms of the Questionnaire on Eating and Weight Patterns in the assessment of children's eating-disordered behaviors. Int J Eat Disord (2004) 1.03
Laboratory-Based Studies of Eating among Children and Adolescents. Curr Nutr Food Sci (2007) 1.03
Energy intake and energy expenditure among children with polymorphisms of the melanocortin-3 receptor. Am J Clin Nutr (2009) 1.03
Impaired insulin secretion in the Turner metabolic syndrome. J Clin Endocrinol Metab (2004) 1.02
Estimates of body fat in children by Hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution. J Pediatr Gastroenterol Nutr (2006) 1.01
Psychological symptoms and insulin sensitivity in adolescents. Pediatr Diabetes (2009) 1.01
Body dissatisfaction, self-esteem, and overweight among inner-city Hispanic children and adolescents. J Adolesc Health (2005) 1.00
Effects of orlistat on fat-soluble vitamins in obese adolescents. Pharmacotherapy (2002) 0.99
Longitudinal study of depressive symptoms and progression of insulin resistance in youth at risk for adult obesity. Diabetes Care (2011) 0.99
Prediction equations for resting energy expenditure in overweight and normal-weight black and white children. Am J Clin Nutr (2004) 0.98
Puberty and observed energy intake: boy, can they eat! Am J Clin Nutr (2010) 0.97
Eating patterns in youth with and without loss of control eating. Int J Eat Disord (2012) 0.97
Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clin Gastroenterol Hepatol (2006) 0.96
Efficacy of orlistat as an adjunct to behavioral treatment in overweight African American and Caucasian adolescents with obesity-related co-morbid conditions. J Pediatr Endocrinol Metab (2004) 0.96
An examination of the interpersonal model of loss of control eating in children and adolescents. Behav Res Ther (2010) 0.96
Effects of a low glycemic load or a low-fat dietary intervention on body weight in obese Hispanic American children and adolescents: a randomized controlled trial. Am J Clin Nutr (2012) 0.94
Subtyping children and adolescents with loss of control eating by negative affect and dietary restraint. Behav Res Ther (2008) 0.94
A low-fat intake and greater activity level are associated with lower weight regain 3 years after completing a very-low-calorie diet. J Am Diet Assoc (2002) 0.92
Childhood obesity. Child Adolesc Psychiatr Clin N Am (2002) 0.91
Differences in insulin secretion and sensitivity of Caucasian and African American prepubertal children. J Pediatr (2002) 0.91
Comparison of child interview and parent reports of children's eating disordered behaviors. Eat Behav (2005) 0.90
Hormonal correlates of clozapine-induced weight gain in psychotic children: an exploratory study. J Am Acad Child Adolesc Psychiatry (2005) 0.90
Sequence variants of the POMC gene and their associations with body composition in children. Obes Res (2003) 0.89
Self-reported vs. actual energy intake in youth with and without loss of control eating. Eat Behav (2010) 0.89
Links between mothers' and children's disinhibited eating and children's adiposity. Appetite (2010) 0.88
Patients with classic congenital adrenal hyperplasia have decreased epinephrine reserve and defective glucose elevation in response to high-intensity exercise. J Clin Endocrinol Metab (2004) 0.87
Pre-meal affective state and laboratory test meal intake in adolescent girls with loss of control eating. Appetite (2013) 0.86
Effects of the human immunodeficiency virus-protease inhibitor, ritonavir, on basal and catecholamine-stimulated lipolysis. J Clin Endocrinol Metab (2005) 0.86
Rapid weight gain during infancy as a predictor of adult obesity. Am J Clin Nutr (2003) 0.86
Sexual dimorphisms in the associations of BMI and body fat with indices of pubertal development in girls and boys. J Clin Endocrinol Metab (2014) 0.85
Treatment of pediatric and adolescent obesity. JAMA (2003) 0.85
Latent profile analysis to determine the typology of disinhibited eating behaviors in children and adolescents. J Consult Clin Psychol (2012) 0.85
Links of adolescent- and parent-reported eating in the absence of hunger with observed eating in the absence of hunger. Obesity (Silver Spring) (2013) 0.85
Impaired glucose tolerance in obese children and adolescents. N Engl J Med (2002) 0.84
Weight and its relationship to adolescent perceptions of their providers (WRAP): a qualitative and quantitative assessment of teen weight-related preferences and concerns. J Adolesc Health (2005) 0.84
Estimation of insulin sensitivity in children: methods, measures and controversies. Pediatr Diabetes (2014) 0.84
Binge eating and weight-related quality of life in obese adolescents. Nutrients (2012) 0.84
Depressive symptoms and cardiorespiratory fitness in obese adolescents. J Adolesc Health (2011) 0.84
Core body temperature in obesity. Am J Clin Nutr (2011) 0.83
Sex-associated differences in free fatty acid flux of obese adolescents. J Clin Endocrinol Metab (2013) 0.83
Metabolic characterization of adults with binge eating in the general population: the Framingham Heart Study. Obesity (Silver Spring) (2014) 0.83
Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity. Obesity (Silver Spring) (2013) 0.83
Very low levels of energy expenditure among pre-adolescent Mexican-American girls. Int J Pediatr Obes (2008) 0.82