Published in J Mass Spectrom on February 01, 2002
Pharmacological properties of the ubiquitous natural product betulin. Eur J Pharm Sci (2006) 2.00
Rapid and sensitive drug metabolism studies by SU-8 microchip capillary electrophoresis-electrospray ionization mass spectrometry. J Chromatogr A (2010) 1.44
Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme. J Biol Chem (2002) 1.31
Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos (2003) 1.22
UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly. Drug Metab Dispos (2008) 1.13
Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos (2005) 1.06
Interfacing an aspiration ion mobility spectrometer to a triple quadrupole mass spectrometer. Rev Sci Instrum (2007) 1.02
Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat. Anesth Analg (2006) 1.00
Glass microfabricated nebulizer chip for mass spectrometry. Lab Chip (2007) 0.99
Analysis of acetylcholine and choline in microdialysis samples by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.96
Electrospray encapsulation of hydrophilic and hydrophobic drugs in poly(L-lactic acid) nanoparticles. Small (2009) 0.94
Acetylcholinesterase inhibitory guided fractionation of Melissa officinalis L. Bioorg Med Chem (2008) 0.94
Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9. Drug Metab Dispos (2011) 0.93
Microchip technology in mass spectrometry. Mass Spectrom Rev (2010) 0.92
Automated ambient desorption-ionization platform for surface imaging integrated with a commercial Fourier transform ion cyclotron resonance mass spectrometer. Anal Chem (2009) 0.92
Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites. Rapid Commun Mass Spectrom (2006) 0.92
Betulin-derived compounds as inhibitors of alphavirus replication. J Nat Prod (2009) 0.91
Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. Drug Metab Dispos (2008) 0.91
Anti-leishmanial activity of betulin derivatives. J Antibiot (Tokyo) (2010) 0.91
Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase. Mol Cell Biol (2009) 0.91
Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. J Am Soc Mass Spectrom (2005) 0.90
Solid-phase synthesis of 1,2,3-triazoles via 1,3-dipolar cycloaddition. J Comb Chem (2003) 0.89
Introduction to micro-analytical systems: bioanalytical and pharmaceutical applications. Eur J Pharm Sci (2003) 0.89
Desorption atmospheric pressure photoionization. Anal Chem (2007) 0.88
Development of LC/MS/MS methods for cocktail dosed Caco-2 samples using atmospheric pressure photoionization and electrospray ionization. Anal Chem (2003) 0.88
Atmospheric pressure photoionization mass spectrometry. Ionization mechanism and the effect of solvent on the ionization of naphthalenes. Anal Chem (2002) 0.88
Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation. Biochem Pharmacol (2007) 0.88
Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors. J Neurosci (2009) 0.87
Analysis of intact glucuronides and sulfates of serotonin, dopamine, and their phase I metabolites in rat brain microdialysates by liquid chromatography-tandem mass spectrometry. Anal Chem (2009) 0.87
Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives. Bioorg Med Chem (2010) 0.87
Characterization of the in vitro metabolic profile of amlodipine in rat using liquid chromatography-mass spectrometry. Eur J Pharm Sci (2007) 0.87
Fully microfabricated and integrated SU-8-based capillary electrophoresis-electrospray ionization microchips for mass spectrometry. Anal Chem (2007) 0.86
Comparison of different amino acid derivatives and analysis of rat brain microdialysates by liquid chromatography tandem mass spectrometry. Anal Chim Acta (2008) 0.86
Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae. Biochem Pharmacol (2010) 0.85
Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates. PLoS One (2013) 0.85
Solid-phase synthesis of amino acid derived N-unsubstituted pyrazoles via sydnones. Org Lett (2009) 0.85
Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers. Phytochemistry (2002) 0.85
Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17. J Med Chem (2006) 0.85
Determination of neutral carbohydrates by CZE with direct UV detection. Electrophoresis (2007) 0.85
Discovery of dopamine glucuronide in rat and mouse brain microdialysis samples using liquid chromatography tandem mass spectrometry. Anal Chem (2009) 0.84
(+)-Dehydroabietic acid, an abietane-type diterpene, inhibits Staphylococcus aureus biofilms in vitro. Int J Mol Sci (2013) 0.84
Simultaneous detection of nonpolar and polar compounds by heat-assisted laser ablation electrospray ionization mass spectrometry. Anal Chem (2012) 0.84
The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific, and may involve both monomers. Biochem Pharmacol (2004) 0.83
Rapid analysis of metabolites and drugs of abuse from urine samples by desorption electrospray ionization-mass spectrometry. Analyst (2007) 0.83
Determination of steroids and their intact glucuronide conjugates in mouse brain by capillary liquid chromatography-tandem mass spectrometry. Anal Chem (2010) 0.83
Current status and future prospects of C1 domain ligands as drug candidates. Curr Top Med Chem (2011) 0.83
Microchip for combining gas chromatography or capillary liquid chromatography with atmospheric pressure photoionization-mass spectrometry. Anal Chem (2007) 0.83
New surfaces for desorption electrospray ionization mass spectrometry: porous silicon and ultra-thin layer chromatography plates. Rapid Commun Mass Spectrom (2006) 0.83
Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays. Anal Biochem (2006) 0.83
UDP-glucuronic acid binds first and the aglycone substrate binds second to form a ternary complex in UGT1A9-catalyzed reactions, in both the presence and absence of bovine serum albumin. Drug Metab Dispos (2012) 0.82
Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma. PLoS One (2013) 0.82
Liquid chromatography/mass spectrometry in anabolic steroid analysis--optimization and comparison of three ionization techniques: electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization. J Mass Spectrom (2002) 0.82
Total synthesis of bistramide A and its 36(Z) isomers: differential effect on cell division, differentiation, and apoptosis. Chemistry (2012) 0.82
Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver. Arch Toxicol (2006) 0.82
Feasibility of SU-8-based capillary electrophoresis-electrospray ionization mass spectrometry microfluidic chips for the analysis of human cell lysates. Electrophoresis (2010) 0.82
Microchip atmospheric pressure chemical ionization source for mass spectrometry. Anal Chem (2004) 0.82
High-performance liquid chromatographic determination of oligomeric procyanidins from dimers up to the hexamer in hawthorn. J Chromatogr A (2002) 0.82
Performance of SU-8 microchips as separation devices and comparison with glass microchips. Anal Chem (2007) 0.82
Glucuronidation of racemic O-desmethyltramadol, the active metabolite of tramadol. Eur J Pharm Sci (2010) 0.82
Easy ambient sonic-spray ionization-membrane interface mass spectrometry for direct analysis of solution constituents. Anal Chem (2008) 0.81
Discovery of neurosteroid glucuronides in mouse brain. Anal Chim Acta (2009) 0.81
Tetraalkylammonium halides as chemical standards for positive electrospray ionization with ion mobility spectrometry/mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.81
Design, synthesis, and biological activity of isophthalic acid derivatives targeted to the C1 domain of protein kinase C. J Med Chem (2009) 0.81
Atmospheric pressure photoionization-mass spectrometry with a microchip heated nebulizer. Anal Chem (2004) 0.81
Carbohydrate and steroid analysis by desorption electrospray ionization mass spectrometry. Chem Commun (Camb) (2008) 0.81
Partitioning of tetra- and pentabromo diphenyl ether and benzo[a]pyrene among water and dissolved and particulate organic carbon along a salinity gradient in coastal waters. Environ Toxicol Chem (2010) 0.81
Metabolite profile of sibutramine in human urine: a liquid chromatography-electrospray ionization mass spectrometric study. J Mass Spectrom (2006) 0.81
Spatial distribution of glycerophospholipids in the ocular lens. PLoS One (2011) 0.81
Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors. J Neurochem (2005) 0.81
Evaluation of cocktail approach to standardise Caco-2 permeability experiments. Eur J Pharm Biopharm (2006) 0.81
Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent. PLoS One (2013) 0.81
Laser ablation atmospheric pressure photoionization mass spectrometry imaging of phytochemicals from sage leaves. Rapid Commun Mass Spectrom (2014) 0.81
Surface assisted laser desorption/ionization on two-layered amorphous silicon coated hybrid nanostructures. J Am Soc Mass Spectrom (2009) 0.80
A new insight into solid-state conformation of macrolide antibiotics. Bioorg Med Chem (2007) 0.80
Hybrid ceramic polymers: new, nonbiofouling, and optically transparent materials for microfluidics. Anal Chem (2010) 0.80