Published in Blood on March 01, 2002
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Dindel: accurate indel calls from short-read data. Genome Res (2010) 8.62
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Periodic lamellipodial contractions correlate with rearward actin waves. Cell (2004) 6.46
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data. Nucleic Acids Res (2013) 5.66
Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet (2012) 5.16
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell (2010) 5.05
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet (2009) 4.24
A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood (2009) 3.63
Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource. Nat Genet (2009) 3.59
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
A no-prophylaxis platelet-transfusion strategy for hematologic cancers. N Engl J Med (2013) 2.90
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet (2012) 2.80
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73
Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell (2011) 2.30
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood (2009) 2.25
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Appl Physiol (1985) (2002) 2.15
Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR. PLoS Pathog (2011) 2.15
Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell Stem Cell (2011) 2.13
Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat Med (2005) 2.01
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome. Nat Genet (2011) 1.91
Genomic analysis reveals a point mutation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus. Antimicrob Agents Chemother (2008) 1.89
A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J Cell Biol (2005) 1.88
A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. Blood (2009) 1.85
A genome-wide association study identifies three loci associated with mean platelet volume. Am J Hum Genet (2008) 1.81
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes (2011) 1.78
End-to-end electronic control of the hospital transfusion process to increase the safety of blood transfusion: strengths and weaknesses. Transfusion (2006) 1.71
Multiple loci are associated with white blood cell phenotypes. PLoS Genet (2011) 1.65
Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone. FASEB J (2002) 1.64
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Diabetes (2008) 1.64
Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis. Int J Cancer (2007) 1.60
A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood (2012) 1.59
Immunoaffinity separation of plasma proteins by IgY microbeads: meeting the needs of proteomic sample preparation and analysis. Proteomics (2005) 1.58
Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch. Pharmacogenetics (2004) 1.49
Recombinant HPA-1a antibody therapy for treatment of fetomaternal alloimmune thrombocytopenia: proof of principle in human volunteers. Blood (2013) 1.49
Brief review: Supplementing oxygen through an airway exchange catheter: efficacy, complications, and recommendations. Can J Anaesth (2011) 1.48
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. Epigenetics (2014) 1.47
Factors affecting red blood cell storage age at the time of transfusion. Transfusion (2013) 1.47
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood (2008) 1.45
Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS. Mol Cell Proteomics (2002) 1.44
Blood pressure loci identified with a gene-centric array. Am J Hum Genet (2011) 1.44
CHRNA4 and tobacco dependence: from gene regulation to treatment outcome. Arch Gen Psychiatry (2007) 1.44
A transdisciplinary model integrating genetic, physiological, and psychological correlates of voluntary exercise. Health Psychol (2007) 1.43
The difficult airway with recommendations for management--part 2--the anticipated difficult airway. Can J Anaesth (2013) 1.42
Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet (2011) 1.41
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet (2011) 1.40
Immunoplatelet counting: potential for reducing the use of platelet transfusions through more accurate platelet counting. Br J Haematol (2003) 1.39
Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens. J Biol Chem (2004) 1.33
Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets. J Biol Chem (2006) 1.32
Clinical controversies: etomidate as an induction agent for endotracheal intubation in patients with sepsis: continue to use etomidate for intubation of patients with septic shock. Ann Emerg Med (2008) 1.30
Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene. Hum Mol Genet (2011) 1.29
Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. J Bacteriol (2007) 1.29
A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. FASEB J (2008) 1.29
The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton. J Biol Chem (2007) 1.28
Concepts of blood transfusion in adults. Lancet (2013) 1.28
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
Redox control of the survival of healthy and diseased cells. Antioxid Redox Signal (2011) 1.27
Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med (2012) 1.27
Establishment of the first World Health Organization International Genetic Reference Panel for quantitation of BCR-ABL mRNA. Blood (2010) 1.26
Platelet genomics and proteomics in human health and disease. J Clin Invest (2005) 1.24
Loaded wheel running and muscle adaptation in the mouse. Am J Physiol Heart Circ Physiol (2005) 1.23
Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. Br J Haematol (2009) 1.21
A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain. J Biol Chem (2004) 1.19
Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood. Blood (2003) 1.18
Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. Blood (2010) 1.16
Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood (2003) 1.14
Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells. Brain (2013) 1.12
Microarray-based genotyping for blood groups: comparison of gene array and 5'-nuclease assay techniques with human platelet antigen as a model. Transfusion (2005) 1.10
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res (2013) 1.10
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. FASEB J (2005) 1.09
Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution. PLoS One (2010) 1.09
MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Dev Biol (2006) 1.09
Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level. J Neuroimmunol (2013) 1.08
The difficult airway with recommendations for management--part 1--difficult tracheal intubation encountered in an unconscious/induced patient. Can J Anaesth (2013) 1.08
Management and outcome of 200 cases of fetomaternal alloimmune thrombocytopenia. Transfusion (2007) 1.07