Published in Nat Genet on February 08, 2009
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Cohort Profile: the international childhood cardiovascular cohort (i3C) consortium. Int J Epidemiol (2012) 1.10
Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk. BMC Med Genet (2011) 1.09
MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3'-UTR via altered RNA structure. RNA Biol (2012) 1.08
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Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. BMC Med Genet (2011) 1.06
Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus. Cancer Res (2011) 1.05
The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients. Diabetes (2011) 1.05
Utility of genetic determinants of lipids and cardiovascular events in assessing risk. Nat Rev Cardiol (2011) 1.04
Stem cell models of cardiac development and disease. Annu Rev Cell Dev Biol (2010) 1.03
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The past, present, and future of direct-to-consumer genetic tests. Dialogues Clin Neurosci (2010) 1.01
Genetics of coronary artery disease. Circulation (2013) 1.00
Plasma lipid composition and risk of developing cardiovascular disease. PLoS One (2013) 0.99
Implications of discoveries from genome-wide association studies in current cardiovascular practice. World J Cardiol (2011) 0.97
Genetics of atherosclerosis. Trends Genet (2012) 0.97
Association tests for X-chromosomal markers--a comparison of different test statistics. Hum Hered (2011) 0.97
A systems biology approach to understanding atherosclerosis. EMBO Mol Med (2010) 0.97
RhCE protein variants in Southwestern Germany detected by serologic routine testing. Transfusion (2009) 0.97
The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population. Am J Hum Genet (2013) 0.96
Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study. Circ Cardiovasc Genet (2009) 0.96
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study. BMC Med Genet (2013) 0.95
Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension (2013) 0.95
Genetic determinants influencing human serum metabolome among African Americans. PLoS Genet (2014) 0.95
Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. PLoS One (2012) 0.94
RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function. PLoS Genet (2013) 0.94
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Genetics of diabetes complications. Curr Diab Rep (2010) 0.93
Genetic variants associated with myocardial infarction and the risk factors in Chinese population. PLoS One (2014) 0.92
Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice. Circ Cardiovasc Genet (2012) 0.92
Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke (2012) 0.91
Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke. Eur J Neurol (2012) 0.91
Genetic causes of myocardial infarction: new insights from genome-wide association studies. Dtsch Arztebl Int (2010) 0.90
ACPA: automated cluster plot analysis of genotype data. BMC Proc (2009) 0.90
The impact of phospholipid transfer protein (PLTP) on lipoprotein metabolism. Nutr Metab (Lond) (2012) 0.90
Association of SNP rs17465637 on chromosome 1q41 and rs599839 on 1p13.3 with myocardial infarction in an American caucasian population. Ann Hum Genet (2011) 0.89
Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report. PLoS Genet (2011) 0.89
Association of CDKN2BAS polymorphism rs4977574 with coronary heart disease: a case-control study and a meta-analysis. Int J Mol Sci (2014) 0.88
Evaluation of single-nucleotide polymorphism imputation using random forests. BMC Proc (2009) 0.88
Sex-specific differences in effect size estimates at established complex trait loci. Int J Epidemiol (2012) 0.87
Molecular genetics of coronary artery disease. J Hum Genet (2015) 0.87
Genomics of heart failure. Heart Fail Clin (2010) 0.87
Association between genetics of diabetes, coronary artery disease, and macrovascular complications: exploring a common ground hypothesis. Rev Diabet Stud (2011) 0.87
Implications of genetic polymorphisms in inflammation-induced atherosclerosis. Open Cardiovasc Med J (2010) 0.86
Peroxisome proliferator-activated receptor gamma polymorphisms and coronary heart disease. PPAR Res (2009) 0.86
The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells. Atherosclerosis (2011) 0.86
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies. Int J Epidemiol (2016) 0.85
Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record. BMC Cardiovasc Disord (2011) 0.85
Pathway analysis of body mass index genome-wide association study highlights risk pathways in cardiovascular disease. Sci Rep (2015) 0.85
Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study. PLoS One (2014) 0.85
New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains. Physiol Genomics (2013) 0.84
Meta-analysis of low density lipoprotein receptor (LDLR) rs2228671 polymorphism and coronary heart disease. Biomed Res Int (2014) 0.84
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Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
The fine-scale structure of recombination rate variation in the human genome. Science (2004) 17.05
Estimation of significance thresholds for genomewide association scans. Genet Epidemiol (2008) 8.88
Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20
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Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet (2008) 3.61
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The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes. Mol Biol Cell (2007) 1.30
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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
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The structure of haplotype blocks in the human genome. Science (2002) 50.88
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Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
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