PubRank

Phillip I Bird

Author PubWeight™ 63.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common fold mediates vertebrate defense and bacterial attack. Science 2007 3.43
2 The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 2010 2.23
3 The MACPF/CDC family of pore-forming toxins. Cell Microbiol 2008 2.15
4 Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 2013 1.53
5 The major human and mouse granzymes are structurally and functionally divergent. J Cell Biol 2006 1.48
6 Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin. J Biol Chem 2005 1.39
7 The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency. J Immunol 2003 1.32
8 Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems. J Biol Chem 2010 1.32
9 Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6. Cancer Res 2004 1.24
10 The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J Biol Chem 2005 1.21
11 Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions. J Biol Chem 2010 1.14
12 Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells. J Biol Chem 2006 1.13
13 A role for granzyme M in TLR4-driven inflammation and endotoxicosis. J Immunol 2010 1.13
14 Extracellular granzymes: current perspectives. Biol Chem 2006 1.12
15 A central role for Bid in granzyme B-induced apoptosis. J Biol Chem 2004 1.10
16 Granzyme B encoded by the commonly occurring human RAH allele retains pro-apoptotic activity. J Biol Chem 2004 1.07
17 Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells. Mol Cell Biol 2005 1.04
18 Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics 2002 1.03
19 Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. Eur J Immunol 2003 1.02
20 Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1). J Biol Chem 2002 1.02
21 Cathepsin H is an additional convertase of pro-granzyme B. J Biol Chem 2010 0.99
22 Maspin (SERPINB5) is an obligate intracellular serpin. J Biol Chem 2010 0.99
23 Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis. Biochemistry 2003 0.98
24 Analysis of vertebrate genomes suggests a new model for clade B serpin evolution. BMC Genomics 2005 0.97
25 Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid. Diabetes 2006 0.96
26 Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis. J Cell Biol 2006 0.95
27 Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor. Mol Immunol 2007 0.95
28 Elucidation of the substrate specificity of the C1s protease of the classical complement pathway. J Biol Chem 2005 0.94
29 Epigenetic heterochromatin markers distinguish terminally differentiated leukocytes from incompletely differentiated leukemia cells in human blood. Exp Hematol 2006 0.93
30 Are all granzymes cytotoxic in vivo? Biol Chem 2014 0.92
31 Mechanisms of serpin dysfunction in disease. Expert Rev Mol Med 2006 0.92
32 Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor. J Biol Chem 2008 0.92
33 Expression, purification and characterization of recombinant Z alpha(1)-antitrypsin--the most common cause of alpha(1)-antitrypsin deficiency. Protein Expr Purif 2009 0.91
34 Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi. BMC Evol Biol 2012 0.91
35 Probing the efficiency of proteolytic events by positional proteomics. Mol Cell Proteomics 2010 0.91
36 Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement. Immunol Cell Biol 2008 0.90
37 Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke. Mol Cell Biol 2004 0.89
38 SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes. J Biochem 2007 0.88
39 Structure of granzyme C reveals an unusual mechanism of protease autoinhibition. Proc Natl Acad Sci U S A 2009 0.88
40 Intercellular communication via the endo-lysosomal system: translocation of granzymes through membrane barriers. Biochim Biophys Acta 2011 0.86
41 A renaissance in understanding the multiple and diverse functions of granzymes? Immunity 2008 0.85
42 Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function. Acta Neuropathol 2015 0.85
43 A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice. Genesis 2003 0.85
44 Assembly of streptolysin O pores assessed by quartz crystal microbalance and atomic force microscopy provides evidence for the formation of anchored but incomplete oligomers. Biochim Biophys Acta 2015 0.84
45 Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus. Biochem Biophys Res Commun 2002 0.83
46 Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing. J Biol Chem 2008 0.83
47 Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation. Immunol Cell Biol 2012 0.81
48 Production of serpins using yeast expression systems. Methods 2004 0.81
49 Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A. J Biol Chem 2014 0.81
50 Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9. J Cell Biochem 2005 0.81
51 The perforin pore facilitates the delivery of cationic cargos. J Biol Chem 2014 0.79
52 Use of granzyme B-based fluorescent protein reporters to monitor granzyme distribution and granule integrity in live cells. Biol Chem 2010 0.79
53 A versatile monoclonal antibody specific to human SERPINB5. Hybridoma (Larchmt) 2012 0.78
54 Serpins 2005 - fun between the beta-sheets. Meeting report based upon presentations made at the 4th International Symposium on Serpin Structure, Function and Biology (Cairns, Australia). FEBS J 2005 0.78
55 Distribution of serine proteinase inhibitor, clade B, member 6 (Serpinb6) in the adult mouse brain. Brain Res Gene Expr Patterns 2002 0.77
56 Serpins: finely balanced conformational traps. IUBMB Life 2002 0.77
57 Predicting serpin/protease interactions. Methods Enzymol 2011 0.77
58 Immunodetection of granzyme B tissue distribution and cellular localisation. Methods Mol Biol 2012 0.77
59 Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration. Am J Nephrol 2006 0.77
60 Intracellular production of recombinant serpins in yeast. Methods Enzymol 2011 0.76
61 The human serpin proteinase inhibitor-9 self-associates at physiological temperatures. Protein Sci 2004 0.76
62 Conservation of the extended substrate specificity profiles among homologous granzymes across species. Mol Cell Proteomics 2013 0.75
63 Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear. Am J Pathol 2013 0.75
64 Biology of serpins. Preface. Methods Enzymol 2011 0.75
65 Blessing or curse? Proteomics in granzyme research. Proteomics Clin Appl 2014 0.75
66 Serpin structure and evolution. Preface. Methods Enzymol 2011 0.75
67 Cloning and characterising an unusual perforin from chicken (Gallus gallus). Dev Comp Immunol 2013 0.75