Published in Mol Cell Biol on March 01, 2002
Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. Blood (2005) 1.44
Development of a Sox2 reporter system modeling cellular heterogeneity in glioma. Neuro Oncol (2014) 0.88
Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages. Cancer Res (2010) 0.82
Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Chem Biol (2012) 0.81
The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase. Biochem J (2006) 0.80
Bimolecular fluorescence complementation demonstrates that the c-Fes protein-tyrosine kinase forms constitutive oligomers in living cells. Biochemistry (2009) 0.76
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene (1989) 60.30
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res (1989) 22.73
Cytochemical identification of monocytes and granulocytes. Am J Clin Pathol (1971) 20.35
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science (1994) 7.60
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood (1998) 6.81
Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci U S A (1980) 6.65
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature (1998) 5.24
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J (1996) 5.17
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature (1989) 4.43
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science (1997) 4.29
Nucleotide sequence of Fujinami sarcoma virus: evolutionary relationship of its transforming gene with transforming genes of other sarcoma viruses. Cell (1982) 4.06
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J (1995) 3.40
CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Mol Cell Biol (1998) 3.19
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases. Mol Cell Biol (1996) 2.94
Current concepts: immunology. Monocytes and macrophages. N Engl J Med (1988) 2.92
Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes. Cell (1982) 2.78
JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol (1994) 2.55
Specific and redundant roles of Src and Fyn in organizing the cytoskeleton. Nature (1995) 2.22
The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J Biol Chem (1993) 2.20
Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation (1997) 2.12
Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites. J Exp Med (1991) 2.10
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation. Science (1993) 2.06
A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr Biol (1997) 2.03
Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science (1991) 1.97
A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein. Cell (1982) 1.86
Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells. Proc Natl Acad Sci U S A (1985) 1.83
Activation of the transformation potential of the cellular fps gene. Cell (1985) 1.75
PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity (1995) 1.72
Inhibition of c-Abl tyrosine kinase activity by filamentous actin. J Biol Chem (2001) 1.71
The structure of the human c-fes/fps proto-oncogene. EMBO J (1985) 1.70
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Mol Cell Biol (1994) 1.67
Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. Mol Cell Biol (1989) 1.64
Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol Cell Biol (1997) 1.63
A fps gene without gag gene sequences transforms cells in culture and induces tumors in chickens. J Virol (1983) 1.63
Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein. Mol Cell Biol (1985) 1.57
Transcription factors that regulate monocyte/macrophage differentiation. J Leukoc Biol (1998) 1.55
Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration. Nucleic Acids Res (1991) 1.46
Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides. Mol Cell Biol (1993) 1.45
Nucleotide sequence and topography of chicken c-fps. Genesis of a retroviral oncogene encoding a tyrosine-specific protein kinase. J Mol Biol (1985) 1.35
c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3. EMBO J (1993) 1.29
Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. Blood (1999) 1.25
Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloid-committed leukemic cell lines. Blood (1992) 1.25
Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes. J Biol Chem (1996) 1.24
Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells. J Biol Chem (1997) 1.21
The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice. Mol Cell Biol (1994) 1.21
Tissue factor in the pathogenesis of atherosclerosis. Thromb Haemost (1997) 1.18
The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells. Oncogene (1997) 1.17
Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3). J Immunol (1995) 1.15
Use of a promoterless Renilla luciferase vector as an internal control plasmid for transient co-transfection assays of Ras-mediated transcription activation. Biotechniques (1999) 1.13
Myeloid-specific gene expression. J Leukoc Biol (1998) 1.12
Myeloid expression of the human c-fps/fes proto-oncogene in transgenic mice. Mol Cell Biol (1990) 1.11
Proto-oncogene expression and dissection of the myeloid growth to differentiation developmental cascade. Oncogene (1989) 1.11
PU.1 but not ets-2 is essential for macrophage development from embryonic stem cells. Blood (1996) 1.11
A two-step mechanism for recruitment of Pip by PU.1. J Immunol (1998) 1.09
Integrin regulation of an inflammatory effector gene. Direct induction of the tissue factor promoter by engagement of beta 1 or alpha 4 integrin chains. J Immunol (1995) 1.07
Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells. Mol Cell Biol (1985) 1.06
The fps/fes tyrosine kinase is expressed in myeloid, vascular endothelial, epithelial, and neuronal cells and is localized in the trans-golgi network. Cell Growth Differ (1996) 1.06
The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. J Biol Chem (1997) 1.05
Structure of the feline c-fes/fps proto-oncogene: genesis of a retroviral oncogene. J Virol (1987) 1.04
Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II. J Immunol (1997) 1.03
K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation. J Biol Chem (1989) 1.03
Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues. J Biol Chem (1996) 1.01
Human cellular fps/fes cDNA rescued via retroviral shuttle vector encodes myeloid cell NCP92 and has transforming potential. Oncogene Res (1988) 1.00
The v-src oncogene blocks the differentiation of a murine myeloid progenitor cell line and induces a tumorigenic phenotype. Oncogene (1991) 1.00
The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU.1, and a novel transcription factor. Mol Cell Biol (1996) 0.97
Abnormal Stat activation, hematopoietic homeostasis, and innate immunity in c-fes-/- mice. Immunity (2000) 0.96
The Fes protein-tyrosine kinase phosphorylates a subset of macrophage proteins that are involved in cell adhesion and cell-cell signaling. J Biol Chem (1997) 0.95
Phorbol ester-stimulated phosphorylation of PU.1: association with leukemic cell growth inhibition. Blood (1996) 0.95
Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS. Mol Cell Biol (1995) 0.93
Chicken myeloid stem cells infected by retroviruses carrying the v-fps oncogene do not require exogenous growth factors to differentiate in vitro. Cell (1986) 0.90
Targeted disruption of the murine fps/fes proto-oncogene reveals that Fps/Fes kinase activity is dispensable for hematopoiesis. Mol Cell Biol (1999) 0.89
A minimal c-fes cassette directs myeloid-specific expression in transgenic mice. Blood (2000) 0.88
Interaction between alpha 5 beta 1 integrin and secreted fibronectin is involved in macrophage differentiation of human HL-60 myeloid leukemia cells. J Immunol (1999) 0.87
Characterization of two activated mutants of human pp60c-src that escape c-Src kinase regulation by distinct mechanisms. J Biol Chem (1995) 0.87
Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation. J Exp Med (1993) 0.87
Identification of a new adapter protein that may link the common beta subunit of the receptor for granulocyte/macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase. J Biol Chem (1995) 0.84
The c-Fes protein-tyrosine kinase suppresses cytokine-independent outgrowth of myeloid leukemia cells induced by Bcr-Abl. Cancer Res (2000) 0.83
Functional specificity of cytoplasmic and transmembrane tyrosine kinases: identification of 130- and 75-kilodalton substrates of c-fps/fes tyrosine kinase in macrophages. Mol Cell Biol (1994) 0.81
Antisense inhibition of c-fes proto-oncogene blocks PMA-induced macrophage differentiation in HL60 and in FDC-P1/MAC-11 cells. Blood (1997) 0.80
Expression of two myeloid cell-specific genes requires the novel transcription factor, c-fes expression factor. J Biol Chem (1997) 0.77
Selective potentiation of c-fps/fes transforming activity by a phosphatase inhibitor. Oncogene Res (1990) 0.76
Detection of functional haematopoietic stem cell niche using real-time imaging. Nature (2008) 4.06
Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease. Proc Natl Acad Sci U S A (2012) 1.15
Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat. J Virol (2003) 1.02
Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development. Stem Cells (2014) 0.98
Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature. Circulation (2013) 0.91
RCAS/SCL-TVA animal model allows targeted delivery of polyoma middle T oncogene to vascular endothelial progenitors in vivo and results in hemangioma development. Clin Cancer Res (2008) 0.86
Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors. J Biol Chem (2003) 0.80
The Fes tyrosine kinase: a signal transducer that regulates myeloid-specific gene expression through transcriptional activation. Blood Cells Mol Dis (2004) 0.80
Tinkering with transcription factors uncovers plasticity of somatic cells. Genes Cancer (2010) 0.77