PubRank

Pierre-Jean Corringer

Author PubWeight™ 46.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 2008 5.77
2 Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov 2009 3.26
3 A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature 2006 3.04
4 X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature 2011 3.00
5 Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys J 2005 2.33
6 The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol 2002 2.20
7 Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel. Anesth Analg 2009 2.15
8 One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc Natl Acad Sci U S A 2010 1.81
9 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat Struct Mol Biol 2012 1.56
10 Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proc Natl Acad Sci U S A 2011 1.52
11 Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. EMBO J 2013 1.37
12 Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun 2013 1.35
13 Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family. Proc Natl Acad Sci U S A 2011 1.34
14 Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A 2006 1.32
15 Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc Natl Acad Sci U S A 2013 1.32
16 Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A 2002 1.32
17 Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proc Natl Acad Sci U S A 2012 1.22
18 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels. Neuropharmacology 2010 1.16
19 Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel. J Mol Biol 2009 1.07
20 Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints. FEBS Lett 2002 0.96
21 Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment. J Biol Chem 2013 0.89
22 Smoke extracts and nicotine, but not tobacco extracts, potentiate firing and burst activity of ventral tegmental area dopaminergic neurons in mice. Neuropsychopharmacology 2011 0.86
23 Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons. Eur J Neurosci 2004 0.84
24 Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures. J Mol Graph Model 2011 0.80
25 Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC. J Med Chem 2013 0.78
26 Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proc Natl Acad Sci U S A 2013 0.78
27 Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport 2008 0.77
28 Unravelling the conformational plasticity of the extracellular domain of a prokaryotic nAChR homologue in solution by NMR. Biochemistry 2011 0.77
29 [X-ray structures of general anesthetics bound to their molecular targets]. Med Sci (Paris) 2011 0.76
30 Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. J Clin Invest 2016 0.75