Published in FEBS Lett on September 25, 2002
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc Natl Acad Sci U S A (2012) 1.38
Bacteriorhodopsin/amphipol complexes: structural and functional properties. Biophys J (2008) 1.24
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proc Natl Acad Sci U S A (2003) 1.03
Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. J Membr Biol (2008) 0.93
Amphipols for each season. J Membr Biol (2014) 0.93
The use of amphipols as universal molecular adapters to immobilize membrane proteins onto solid supports. Proc Natl Acad Sci U S A (2008) 0.91
Amphipol-assisted folding of bacteriorhodopsin in the presence or absence of lipids: functional consequences. Eur Biophys J (2012) 0.84
Rigid Residue Scan Simulations Systematically Reveal Residue Entropic Roles in Protein Allostery. PLoS Comput Biol (2016) 0.84
Labeling and functionalizing amphipols for biological applications. J Membr Biol (2014) 0.82
All-atom and coarse-grained molecular dynamics simulations of a membrane protein stabilizing polymer. Langmuir (2011) 0.80
A new concept to reveal protein dynamics based on energy dissipation. PLoS One (2011) 0.79
Population shift of binding pocket size and dynamic correlation analysis shed new light on the anticooperative mechanism of PII protein. Proteins (2013) 0.78
Identification of a pre-active conformation of a pentameric channel receptor. Elife (2017) 0.75
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature (2008) 5.77
Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends Cogn Sci (2006) 4.66
Experimental and theoretical approaches to conscious processing. Neuron (2011) 4.28
An atypical haem in the cytochrome b(6)f complex. Nature (2003) 3.52
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov (2009) 3.26
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature (2006) 3.04
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature (2011) 3.00
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci (2003) 2.85
A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proc Natl Acad Sci U S A (2003) 2.79
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nat Methods (2010) 2.77
Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron (2006) 2.69
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys J (2005) 2.33
Membrane protein folding: beyond the two stage model. FEBS Lett (2003) 2.20
The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol (2002) 2.20
Anesthetic sensitivity of the Gloeobacter violaceus proton-gated ion channel. Anesth Analg (2009) 2.15
Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. J Neurosci (2002) 2.05
Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1. EMBO J (2011) 1.90
Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron (2005) 1.89
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc Natl Acad Sci U S A (2010) 1.81
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proc Natl Acad Sci U S A (2002) 1.78
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology (Berl) (2006) 1.76
Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure (2012) 1.69
Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2005) 1.58
A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat Struct Mol Biol (2012) 1.56
Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proc Natl Acad Sci U S A (2011) 1.52
A neuronal model of predictive coding accounting for the mismatch negativity. J Neurosci (2012) 1.48
Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness. PLoS Biol (2005) 1.47
Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proc Natl Acad Sci U S A (2011) 1.44
Executive and social behaviors under nicotinic receptor regulation. Proc Natl Acad Sci U S A (2003) 1.44
Altered map of visual space in the superior colliculus of mice lacking early retinal waves. J Neurosci (2005) 1.38
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. EMBO J (2013) 1.37
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun (2013) 1.35
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family. Proc Natl Acad Sci U S A (2011) 1.34
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc Natl Acad Sci U S A (2013) 1.32
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A (2006) 1.32
Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A (2002) 1.32
Conformational selection or induced fit? 50 years of debate resolved. F1000 Biol Rep (2011) 1.31
Pore conformations and gating mechanism of a Cys-loop receptor. Proc Natl Acad Sci U S A (2005) 1.31
Bacteriorhodopsin/amphipol complexes: structural and functional properties. Biophys J (2008) 1.24
Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. J Leukoc Biol (2006) 1.22
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proc Natl Acad Sci U S A (2012) 1.22
NMR study of a membrane protein in detergent-free aqueous solution. Proc Natl Acad Sci U S A (2005) 1.21
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. EMBO J (2003) 1.19
Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. J Comp Neurol (2003) 1.18
Hemifluorinated surfactants: a non-dissociating environment for handling membrane proteins in aqueous solutions? FEBS Lett (2004) 1.18
Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein. Chemphyschem (2006) 1.18
Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci (2002) 1.17
Nicotine activates immature "silent" connections in the developing hippocampus. Proc Natl Acad Sci U S A (2003) 1.17
3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels. Neuropharmacology (2010) 1.16
Partial specific volume and solvent interactions of amphipol A8-35. Anal Biochem (2004) 1.16
Slow diffusion of macromolecular assemblies by a new pulsed field gradient NMR method. J Am Chem Soc (2003) 1.15
An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J Biol Chem (2004) 1.15
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proc Natl Acad Sci U S A (2007) 1.15
A gating mechanism of pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2013) 1.15
Chaperoning of insertion of membrane proteins into lipid bilayers by hemifluorinated surfactants: application to diphtheria toxin. Biochemistry (2006) 1.14
Dynamics of membrane protein/amphipol association studied by Förster resonance energy transfer: implications for in vitro studies of amphipol-stabilized membrane proteins. Biochemistry (2007) 1.13
α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. FASEB J (2010) 1.12
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. J Physiol (2006) 1.12
Prefrontal nicotinic receptors control novel social interaction between mice. FASEB J (2011) 1.11
Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors. Proc Natl Acad Sci U S A (2010) 1.10
Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proc Natl Acad Sci U S A (2008) 1.08
Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology (2006) 1.08
Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc Natl Acad Sci U S A (2007) 1.08
Ionic strength dependence of protein-polyelectrolyte interactions. Biomacromolecules (2003) 1.08
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proc Natl Acad Sci U S A (2005) 1.08
Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel. J Mol Biol (2009) 1.07
Amphipathic polymers: tools to fold integral membrane proteins to their active form. Biochemistry (2006) 1.06
Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system. Prog Brain Res (2004) 1.05
The emergence of human consciousness: from fetal to neonatal life. Pediatr Res (2009) 1.04
Complex fluorescence of the cyan fluorescent protein: comparisons with the H148D variant and consequences for quantitative cell imaging. Biochemistry (2008) 1.04
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proc Natl Acad Sci U S A (2003) 1.03
Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. J Neurosci (2004) 1.02
Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? J Physiol Paris (2006) 1.01
Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proc Natl Acad Sci U S A (2004) 1.01
A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. C R Biol (2005) 1.01
Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology (2005) 1.00
Well-defined nanoparticles formed by hydrophobic assembly of a short and polydisperse random terpolymer, amphipol A8-35. Langmuir (2006) 0.99
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. Am J Pathol (2009) 0.97
Live imaging of neural structure and function by fibred fluorescence microscopy. EMBO Rep (2006) 0.96
Amphipol-assisted in vitro folding of G protein-coupled receptors. Biochemistry (2009) 0.96
Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. J Comp Neurol (2004) 0.96
Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain (2004) 0.96
Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration. PLoS Comput Biol (2008) 0.95
Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression. EMBO Rep (2002) 0.95
Amphipols and fluorinated surfactants: Two alternatives to detergents for studying membrane proteins in vitro. Methods Mol Biol (2010) 0.94