Published in Mil Med on February 01, 2002
Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses. J Infect Dis (2007) 3.62
Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology (2003) 2.40
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001. Radiat Res (2003) 1.69
History and development of radiation-protective agents. Int J Radiat Biol (2009) 1.68
Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiation. Exp Hematol (2010) 1.56
Wound trauma increases radiation-induced mortality by activation of iNOS pathway and elevation of cytokine concentrations and bacterial infection. Radiat Res (2010) 1.33
gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. Radiat Res (2009) 1.32
Medical countermeasures for radiation combined injury: radiation with burn, blast, trauma and/or sepsis. report of an NIAID Workshop, March 26-27, 2007. Radiat Res (2008) 1.32
Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. Int J Radiat Biol (2009) 1.29
Genistein protects against biomarkers of delayed lung sequelae in mice surviving high-dose total body irradiation. J Radiat Res (2008) 1.29
Genistein induces radioprotection by hematopoietic stem cell quiescence. Int J Radiat Biol (2008) 1.17
Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis. J Infect Dis (2008) 1.13
Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation. Radiat Res (2010) 1.07
Radioprotective effects of oral 17-dimethylaminoethylamino-17-demethoxygeldanamycin in mice: bone marrow and small intestine. Cell Biosci (2013) 1.05
Combined injury: factors with potential to impact radiation dose assessments. Health Phys (2010) 1.04
Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): a review. Cytokine (2015) 1.03
Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. Haematologica (2010) 1.03
Radiation countermeasure agents: an update (2011-2014). Expert Opin Ther Pat (2014) 1.02
Effects of genistein administration on cytokine induction in whole-body gamma irradiated mice. Int Immunopharmacol (2009) 1.01
Wound trauma alters ionizing radiation dose assessment. Cell Biosci (2012) 1.01
Genistein treatment protects mice from ionizing radiation injury. J Appl Toxicol (2003) 0.99
Pathologic changes associated with brucellosis experimentally induced by aerosol exposure in rhesus macaques (Macaca mulatta). Am J Vet Res (2004) 0.99
Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures. J Radiat Res (2013) 0.98
Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. Radiat Res (2011) 0.98
Management of postirradiation infection: lessons learned from animal models. Mil Med (2004) 0.98
Influence of sublethal total-body irradiation on immune cell populations in the intestinal mucosa. Radiat Res (2010) 0.97
Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. Int Immunopharmacol (2012) 0.97
Subcutaneous administration of genistein prior to lethal irradiation supports multilineage, hematopoietic progenitor cell recovery and survival. Int J Radiat Biol (2007) 0.96
Nutritional approaches to radioprotection: vitamin E. Mil Med (2002) 0.96
Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys (2010) 0.96
Induction of cytokines by radioprotective tocopherol analogs. Exp Mol Pathol (2006) 0.96
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res (2010) 0.95
Pathogenesis of aerosolized Eastern Equine Encephalitis virus infection in guinea pigs. Virol J (2009) 0.95
Antibacterial activity of the soy isoflavone genistein. J Basic Microbiol (2006) 0.95
Hematological targets of radiation damage. Curr Drug Targets (2010) 0.95
Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms. Radiat Res (2009) 0.92
Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. J Radiat Res (2012) 0.92
Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile. Health Phys (2015) 0.91
Determination of sample sizes for demonstrating efficacy of radiation countermeasures. Biometrics (2009) 0.91
Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria. Mol Cell Biochem (2005) 0.91
Preclinical development of a bridging therapy for radiation casualties. Exp Hematol (2010) 0.90
α-Tocopherol succinate protects mice against radiation-induced gastrointestinal injury. Radiat Res (2011) 0.90
Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus). J Am Assoc Lab Anim Sci (2010) 0.88
Skin injuries reduce survival and modulate corticosterone, C-reactive protein, complement component 3, IgM, and prostaglandin E 2 after whole-body reactor-produced mixed field (n + γ-photons) irradiation. Oxid Med Cell Longev (2013) 0.87
Delta-tocotrienol protects mice from radiation-induced gastrointestinal injury. Radiat Res (2013) 0.87
A TPO receptor agonist, ALXN4100TPO, mitigates radiation-induced lethality and stimulates hematopoiesis in CD2F1 mice. Radiat Res (2011) 0.87
Sublethal total body irradiation leads to early cerebellar damage and oxidative stress. Curr Neurovasc Res (2010) 0.86
Radioprotection by N-palmitoylated nonapeptide of human interleukin-1beta. Peptides (2005) 0.86
Genistein nanoparticles protect mouse hematopoietic system and prevent proinflammatory factors after gamma irradiation. Radiat Res (2013) 0.83
Mobilized progenitor cells as a bridging therapy for radiation casualties: a brief review of tocopherol succinate-based approaches. Int Immunopharmacol (2011) 0.83
Accelerated hematopoietic syndrome after radiation doses bridging hematopoietic (H-ARS) and gastrointestinal (GI-ARS) acute radiation syndrome: early hematological changes and systemic inflammatory response syndrome in minipig. Int J Radiat Biol (2014) 0.83
α-Tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation-induced gastrointestinal injury in mice. Exp Hematol (2012) 0.83
Radioprotective efficacy and acute toxicity of 5-androstenediol after subcutaneous or oral administration in mice. Immunopharmacol Immunotoxicol (2002) 0.82
Management of postirradiation sepsis. Mil Med (2002) 0.82
New strategies for the prevention of radiation injury: possible implications for countering radiation hazards of long-term space travel. J Radiat Res (2002) 0.82
Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. Int Immunopharmacol (2013) 0.81
Alpha-tocopherol succinate-mobilized progenitors improve intestinal integrity after whole body irradiation. Int J Radiat Biol (2013) 0.81
Alpha-tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation combined injury in mice. J Radiat Res (2013) 0.81
Pharmacodynamic (phase 0) study using etaracizumab in advanced melanoma. J Immunother (2010) 0.80
Health effects of embedded depleted uranium. Mil Med (2002) 0.80
Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterin. Curr Drug Targets (2010) 0.79
Hemangiopericytoma - the need for a protocol-based treatment plan. Indian J Dent Res (2011) 0.79
Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model. Mol Biosyst (2013) 0.79
Oral delivery of spray dried PLGA/amifostine nanoparticles. J Pharm Pharmacol (2004) 0.78
Susceptibility of irradiated B6D2F1/J mice to Klebsiella pneumoniae administered intratracheally: a pulmonary infection model in an immunocompromised host. Comp Med (2003) 0.78
Preliminary nonclinical toxicity, pharmacokinetics, and pharmacodynamics of ALXN4100TPO, a thrombopoietin receptor agonist, in CD2F1 mice. Int J Toxicol (2013) 0.77
Retrospective analyses of serum lipids and lipoproteins and severity of disease in 60Co-irradiated Sus scrofa domestica and Macaca mulatta. Comp Med (2007) 0.77
Preclinical development of a bridging therapy for radiation casualties: appropriate for high risk personnel. Health Phys (2014) 0.77
Molecular specificity of 5-androstenediol as a systemic radioprotectant in mice. Immunopharmacol Immunotoxicol (2005) 0.77
Captopril modulates hypoxia-inducible factors and erythropoietin responses in a murine model of total body irradiation. Exp Hematol (2010) 0.77
Efficacy of radiation countermeasures depends on radiation quality. Radiat Res (2012) 0.76
Comparison of clarithromycin and ciprofloxacin therapy for Bacillus anthracis Sterne infection in mice with or without (60)Co gamma-photon irradiation. J Med Microbiol (2005) 0.75
Inhibition of LPS-induced nitric oxide production in RAW cells by radioprotective thiols. Exp Mol Pathol (2003) 0.75
Development of chemopreventive strategies for radiation-induced cancer: targeting radiation-induced genetic alterations. Mil Med (2002) 0.75
Targets of potential radioprotective drugs. Curr Drug Targets (2010) 0.75
Determination of WR-1065 and WR-33278 by liquid chromatography with electrochemical detection. J AOAC Int (2002) 0.75
Caspase-dependent and -independent panc-1 cell death due to actinomycin D and MK 886 are additive but increase clonogenic survival. Exp Biol Med (Maywood) (2003) 0.75
Antimicrobial therapies for pulmonary Klebsiella pneumoniae infection in B6D2F1/J mice immunocompromised by use of sublethal irradiation. Comp Med (2004) 0.75
Nuclear, biological, and chemical combined injuries and countermeasures on the battlefield. Mil Med (2002) 0.75
High-dose antibiotic therapy is superior to a 3-drug combination of prostanoids and lipid A derivative in protecting irradiated canines. J Radiat Res (2002) 0.75