Published in Microbes Infect on February 01, 2002
Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathog (2012) 1.44
Ectopic expression of a Neospora caninum Kazal type inhibitor triggers developmental defects in Toxoplasma and Plasmodium. PLoS One (2015) 1.41
The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells. Eukaryot Cell (2004) 1.25
Cathepsin proteases in Toxoplasma gondii. Adv Exp Med Biol (2011) 0.96
The prodomain of Toxoplasma gondii GPI-anchored subtilase TgSUB1 mediates its targeting to micronemes. Traffic (2008) 0.95
Toxoplasma rhoptries: unique secretory organelles and source of promising vaccine proteins for immunoprevention of toxoplasmosis. J Biomed Biotechnol (2008) 0.90
Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro. Eukaryot Cell (2009) 0.88
Changes in the proteomic profiles of mouse brain after infection with cyst-forming Toxoplasma gondii. Parasit Vectors (2013) 0.87
Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1. Traffic (2011) 0.87
Effects of serine protease inhibitors on viability and morphology of Leishmania (Leishmania) amazonensis promastigotes. Parasitol Res (2007) 0.86
Differential gene expression in mice infected with distinct Toxoplasma strains. Infect Immun (2011) 0.85
A cysteine protease inhibitor rescues mice from a lethal Cryptosporidium parvum infection. Antimicrob Agents Chemother (2013) 0.84
Genome sequence of the human malaria parasite Plasmodium falciparum. Nature (2002) 37.89
OrthoMCL: identification of ortholog groups for eukaryotic genomes. Genome Res (2003) 33.03
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups. Nucleic Acids Res (2006) 11.43
PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res (2008) 6.73
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19
Assessing performance of orthology detection strategies applied to eukaryotic genomes. PLoS One (2007) 5.62
Chemical genetics of Plasmodium falciparum. Nature (2010) 5.52
The Plasmodium genome database. Nature (2002) 4.36
Creating a honey bee consensus gene set. Genome Biol (2007) 4.17
ToxoDB: an integrated Toxoplasma gondii database resource. Nucleic Acids Res (2007) 3.96
Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. Nat Rev Microbiol (2004) 3.85
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24
Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum. Science (2003) 3.08
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov (2008) 2.58
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity (2012) 2.52
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog (2006) 2.43
ApiDB: integrated resources for the apicomplexan bioinformatics resource center. Nucleic Acids Res (2006) 2.37
PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res (2002) 2.37
GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Res (2008) 2.35
Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Mol Biol Cell (2002) 2.19
Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups. Curr Protoc Bioinformatics (2011) 2.15
EuPathDB: a portal to eukaryotic pathogen databases. Nucleic Acids Res (2009) 2.11
The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands. J Exp Med (2010) 2.08
The transcriptome of Toxoplasma gondii. BMC Biol (2005) 2.06
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci U S A (2006) 1.95
Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Cell Host Microbe (2010) 1.90
Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science (2009) 1.77
Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene database. Genome Res (2003) 1.75
Organellar dynamics during the cell cycle of Toxoplasma gondii. J Cell Sci (2008) 1.70
Golgi biogenesis in Toxoplasma gondii. Nature (2002) 1.67
A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J Cell Biol (2002) 1.56
Measuring tubulin content in Toxoplasma gondii: a comparison of laser-scanning confocal and wide-field fluorescence microscopy. Proc Natl Acad Sci U S A (2002) 1.55
The road less traveled: transport of Legionella to the endoplasmic reticulum. J Cell Biol (2002) 1.54
EuPathDB: the eukaryotic pathogen database. Nucleic Acids Res (2012) 1.53
Functional inactivation of immature dendritic cells by the intracellular parasite Toxoplasma gondii. J Immunol (2004) 1.49
Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathog (2012) 1.44
Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast. EMBO J (2006) 1.42
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PLoS Negl Trop Dis (2010) 1.39
FungiDB: an integrated functional genomics database for fungi. Nucleic Acids Res (2011) 1.37
Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. PLoS Pathog (2009) 1.37
Toward community standards in the quest for orthologs. Bioinformatics (2012) 1.36
The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. Genome Biol (2008) 1.35
ApiEST-DB: analyzing clustered EST data of the apicomplexan parasites. Nucleic Acids Res (2004) 1.30
Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii. Genome Res (2006) 1.28
Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis. PLoS Pathog (2013) 1.28
Toxoplasma gondii Hsp90 is a potential drug target whose expression and subcellular localization are developmentally regulated. J Mol Biol (2005) 1.27
Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infect Immun (2007) 1.26
Dynamics of Toxoplasma gondii differentiation. Eukaryot Cell (2004) 1.26
A novel multifunctional oligonucleotide microarray for Toxoplasma gondii. BMC Genomics (2010) 1.23
Evolutionary constraints on structural similarity in orthologs and paralogs. Protein Sci (2009) 1.23
Secretory traffic in the eukaryotic parasite Toxoplasma gondii: less is more. J Cell Biol (2002) 1.22
Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii. J Biol Chem (2004) 1.21
Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii. Mol Microbiol (2002) 1.20
Actin filament turnover removes bundles from Drosophila bristle cells. J Cell Sci (2002) 1.19
TDR Targets: a chemogenomics resource for neglected diseases. Nucleic Acids Res (2011) 1.15
Transcriptome of axenic liver stages of Plasmodium yoelii. Mol Biochem Parasitol (2004) 1.14
Actin filament bundles in Drosophila wing hairs: hairs and bristles use different strategies for assembly. Mol Biol Cell (2005) 1.13
Golgi and centrosome cycles in Toxoplasma gondii. Mol Biochem Parasitol (2005) 1.12
Identification of surprisingly diverse type IV pili, across a broad range of gram-positive bacteria. PLoS One (2011) 1.11
Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infect Immun (2009) 1.10
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biol (2011) 1.09
A monomorphic haplotype of chromosome Ia is associated with widespread success in clonal and nonclonal populations of Toxoplasma gondii. MBio (2011) 1.09
Protozoan genomics for drug discovery. Nat Biotechnol (2005) 1.09
AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species. Nucleic Acids Res (2010) 1.08
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. J Immunol (2010) 1.07
Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasites. Mol Microbiol (2003) 1.04
Long continuous actin bundles in Drosophila bristles are constructed by overlapping short filaments. J Cell Biol (2003) 1.04
Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii. J Cell Sci (2005) 1.04
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. PLoS One (2011) 1.04
PlasmoDB v5: new looks, new genomes. Trends Parasitol (2006) 1.03
Variability and heritability of cell division pathways in Toxoplasma gondii. J Cell Sci (2004) 1.03
Evigan: a hidden variable model for integrating gene evidence for eukaryotic gene prediction. Bioinformatics (2008) 1.01
The Strategies WDK: a graphical search interface and web development kit for functional genomics databases. Database (Oxford) (2011) 1.01
N-terminal positively charged amino acids, but not their exact position, are important for apicoplast transit peptide fidelity in Toxoplasma gondii. Mol Biochem Parasitol (2006) 0.96
Differential localization of alternatively spliced hypoxanthine-xanthine-guanine phosphoribosyltransferase isoforms in Toxoplasma gondii. J Biol Chem (2005) 0.96
Amino-terminal control of transgenic protein expression levels in Toxoplasma gondii. Mol Biochem Parasitol (2002) 0.95
In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii. PLoS One (2008) 0.95
cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii. Mol Biochem Parasitol (2003) 0.95
Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii. Eukaryot Cell (2004) 0.95
Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential. J Biol Chem (2010) 0.94
The search for the missing link: a relic plastid in Perkinsus? Int J Parasitol (2011) 0.92
Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice. Infect Immun (2011) 0.91
Functional characterization of a novel Toxoplasma gondii glycosyltransferase: UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3. Arch Biochem Biophys (2004) 0.91
SchistoDB: an updated genome resource for the three key schistosomes of humans. Nucleic Acids Res (2012) 0.91
Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. J Biol Chem (2002) 0.91
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog. J Biol Chem (2006) 0.90
Transcript initiation, polyadenylation, and functional promoter mapping for the dihydrofolate reductase-thymidylate synthase gene of Toxoplasma gondii. Mol Biochem Parasitol (2004) 0.90
Replication and distribution of Toxoplasma gondii in the small intestine after oral infection with tissue cysts. Infect Immun (2013) 0.89
Reranking candidate gene models with cross-species comparison for improved gene prediction. BMC Bioinformatics (2008) 0.88
Malaria vaccines: if at first you don't succeed... Trends Parasitol (2004) 0.87
The Eukaryotic Pathogen Databases: a functional genomic resource integrating data from human and veterinary parasites. Methods Mol Biol (2015) 0.86
Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila. Mol Biol Cell (2007) 0.86
A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion. J Biol Chem (2008) 0.86
Crystal structure of Toxoplasma gondii porphobilinogen synthase: insights on octameric structure and porphobilinogen formation. J Biol Chem (2011) 0.86
Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii. PLoS One (2011) 0.84
PlasmoDB: exploring genomics and post-genomics data of the malaria parasite, Plasmodium falciparum. Redox Rep (2003) 0.83
Pyruvate kinase type-II isozyme in Plasmodium falciparum localizes to the apicoplast. Parasitol Int (2008) 0.82
An insertional trap for conditional gene expression in Toxoplasma gondii: identification of TAF250 as an essential gene. Mol Biochem Parasitol (2010) 0.82