Published in Nucleic Acids Res on November 14, 2007
Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80. Eukaryot Cell (2009) 3.32
Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nat Immunol (2008) 2.45
GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Res (2008) 2.35
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Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii. PLoS One (2010) 2.08
Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases. Proc Natl Acad Sci U S A (2011) 2.02
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Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Cell Host Microbe (2010) 1.90
A unique dual activity amino acid hydroxylase in Toxoplasma gondii. PLoS One (2009) 1.74
Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella. PLoS Biol (2012) 1.67
Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice. PLoS Genet (2009) 1.66
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The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness. Mol Cell Proteomics (2009) 1.56
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A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondii. Cell Microbiol (2011) 1.50
The Apicomplexan whole-genome phylogeny: an analysis of incongruence among gene trees. Mol Biol Evol (2008) 1.48
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Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med (2009) 1.42
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites. Elife (2015) 1.36
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Identification of a sporozoite-specific antigen from Toxoplasma gondii. J Parasitol (2011) 1.28
TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells. PLoS Pathog (2012) 1.27
A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii. PLoS Pathog (2010) 1.27
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A novel multifunctional oligonucleotide microarray for Toxoplasma gondii. BMC Genomics (2010) 1.23
A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. PLoS Pathog (2012) 1.23
Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii. Eukaryot Cell (2009) 1.20
Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites. PLoS Pathog (2011) 1.19
Immunological dominance of Trypanosoma cruzi tandem repeat proteins. Infect Immun (2008) 1.18
Lipoic acid metabolism in microbial pathogens. Microbiol Mol Biol Rev (2010) 1.18
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence. PLoS One (2008) 1.18
Phenotypic and gene expression changes among clonal type I strains of Toxoplasma gondii. Eukaryot Cell (2009) 1.15
Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity. Proc Natl Acad Sci U S A (2012) 1.15
Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One (2012) 1.15
Population genetics of Toxoplasma gondii: new perspectives from parasite genotypes in wildlife. Vet Parasitol (2011) 1.13
Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii. Eukaryot Cell (2012) 1.13
Toxoplasma: the next 100years. Microbes Infect (2008) 1.12
Jumbled genomes: missing Apicomplexan synteny. Mol Biol Evol (2011) 1.11
A thioredoxin family protein of the apicoplast periphery identifies abundant candidate transport vesicles in Toxoplasma gondii. Eukaryot Cell (2008) 1.10
Consistent and contrasting properties of lineage-specific genes in the apicomplexan parasites Plasmodium and Theileria. BMC Evol Biol (2008) 1.09
Inconsistencies of genome annotations in apicomplexan parasites revealed by 5'-end-one-pass and full-length sequences of oligo-capped cDNAs. BMC Genomics (2009) 1.08
Computational analysis and experimental validation of gene predictions in Toxoplasma gondii. PLoS One (2008) 1.08
Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes. BMC Evol Biol (2010) 1.08
AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species. Nucleic Acids Res (2010) 1.08
Whole genome sequencing of a natural recombinant Toxoplasma gondii strain reveals chromosome sorting and local allelic variants. Genome Biol (2009) 1.05
DNA vaccination with a gene encoding Toxoplasma gondii GRA6 induces partial protection against toxoplasmosis in BALB/c mice. Parasit Vectors (2011) 1.04
Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. J Biol Chem (2009) 1.02
Peroxiredoxins in parasites. Antioxid Redox Signal (2012) 1.01
Global analysis of apicomplexan protein S-acyl transferases reveals an enzyme essential for invasion. Traffic (2013) 1.01
Discovery of a novel Toxoplasma gondii conoid-associated protein important for parasite resistance to reactive nitrogen intermediates. J Immunol (2012) 1.01
A kernel for open source drug discovery in tropical diseases. PLoS Negl Trop Dis (2009) 1.00
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis. PLoS Pathog (2011) 0.99
Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development. BMC Genomics (2014) 0.99
Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa. BMC Evol Biol (2011) 0.98
Identification of potential serodiagnostic and subunit vaccine antigens by antibody profiling of toxoplasmosis cases in Turkey. Mol Cell Proteomics (2011) 0.98
Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors. BMC Evol Biol (2013) 0.98
Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. BMC Genomics (2010) 0.98
Tetrahymena Genome Database Wiki: a community-maintained model organism database. Database (Oxford) (2012) 0.98
Targeted proteomic dissection of Toxoplasma cytoskeleton sub-compartments using MORN1. Cytoskeleton (Hoboken) (2012) 0.97
Plasticity between MyoC- and MyoA-glideosomes: an example of functional compensation in Toxoplasma gondii invasion. PLoS Pathog (2014) 0.95
Toxoplasma on the brain: understanding host-pathogen interactions in chronic CNS infection. J Parasitol Res (2012) 0.95
Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes. BMC Genomics (2015) 0.95
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts. PLoS One (2011) 0.95
Development of forward genetics in Toxoplasma gondii. Int J Parasitol (2009) 0.94
Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. Nucleic Acids Res (2012) 0.94
De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs. BMC Genomics (2012) 0.94
Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis. PLoS Comput Biol (2015) 0.94
The histone code of Toxoplasma gondii comprises conserved and unique posttranslational modifications. MBio (2013) 0.93
Global proteomic analysis of the oocyst/sporozoite of Toxoplasma gondii reveals commitment to a host-independent lifestyle. BMC Genomics (2013) 0.92
A Toxoplasma gondii protein with homology to intracellular type Na⁺/H⁺ exchangers is important for osmoregulation and invasion. Exp Cell Res (2011) 0.92
Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii. Mol Syst Biol (2013) 0.92
Gene Set Enrichment Analysis (GSEA) of Toxoplasma gondii expression datasets links cell cycle progression and the bradyzoite developmental program. BMC Genomics (2014) 0.91
Non-canonical maturation of two papain-family proteases in Toxoplasma gondii. J Biol Chem (2012) 0.91
Limited genetic diversity among Sarcocystis neurona strains infecting southern sea otters precludes distinction between marine and terrestrial isolates. Vet Parasitol (2009) 0.91
The secreted kinase ROP18 defends Toxoplasma's border. Bioessays (2011) 0.91
Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii. PLoS Genet (2015) 0.90
Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii. BMC Genomics (2014) 0.89
Cost-effective sequencing of full-length cDNA clones powered by a de novo-reference hybrid assembly. PLoS One (2010) 0.89
β-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria. MBio (2012) 0.89
Phylogenomic analyses of malaria parasites and evolution of their exported proteins. BMC Evol Biol (2011) 0.89
Toxoplasma gondii proteomics. Expert Rev Proteomics (2009) 0.89
Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove. Elife (2016) 0.88
Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains. BMC Genomics (2013) 0.88
Distribution of the SELMA translocon in secondary plastids of red algal origin and predicted uncoupling of ubiquitin-dependent translocation from degradation. Eukaryot Cell (2012) 0.88
Full-parasites: database of full-length cDNAs of apicomplexa parasites, 2010 update. Nucleic Acids Res (2010) 0.87
PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA. Cell Microbiol (2012) 0.87
Forward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acids. Traffic (2011) 0.87
Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence. J Biol Chem (2013) 0.87
Horizontal gene transfer is a significant driver of gene innovation in dinoflagellates. Genome Biol Evol (2013) 0.87
Variable numbers of tandem repeats in Plasmodium falciparum genes. J Mol Evol (2010) 0.87
Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features. PLoS One (2015) 0.86
Apoptosis-like cell death pathways in the unicellular parasite Toxoplasma gondii following treatment with apoptosis inducers and chemotherapeutic agents: a proof-of-concept study. Apoptosis (2013) 0.86
A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii. Nucleic Acids Res (2015) 0.86
Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondii. J Biol Chem (2014) 0.86
Variation detection based on next-generation sequencing of type Chinese 1 strains of Toxoplasma gondii with different virulence from China. BMC Genomics (2015) 0.85
Apicomplexan perforin-like proteins. Commun Integr Biol (2010) 0.85
The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma. PLoS Pathog (2014) 0.85
Processing and presentation of antigens derived from intracellular protozoan parasites. Curr Opin Immunol (2010) 0.84
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell. Elife (2015) 0.84
Genetic manipulation in Δku80 strains for functional genomic analysis of Toxoplasma gondii. J Vis Exp (2013) 0.84
The generic genome browser: a building block for a model organism system database. Genome Res (2002) 42.64
New developments in the InterPro database. Nucleic Acids Res (2007) 12.49
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups. Nucleic Acids Res (2006) 11.43
Toxoplasmic encephalitis in AIDS. Clin Infect Dis (1992) 7.64
The immune epitope database and analysis resource: from vision to blueprint. PLoS Biol (2005) 7.40
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Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J Biol Chem (2005) 3.87
ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog (2006) 2.43
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Design and implementation of microarray gene expression markup language (MAGE-ML). Genome Biol (2002) 16.75
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol (2008) 12.96
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The Drosophila melanogaster Genetic Reference Panel. Nature (2012) 7.94
A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB. BMC Bioinformatics (2006) 7.53
The MGED Ontology: a resource for semantics-based description of microarray experiments. Bioinformatics (2006) 7.37
PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res (2008) 6.73
The genome of the model beetle and pest Tribolium castaneum. Nature (2008) 6.50
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM). Bioinformatics (2011) 6.20
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19
Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature (2008) 5.96
Assessing performance of orthology detection strategies applied to eukaryotic genomes. PLoS One (2007) 5.62
Chemical genetics of Plasmodium falciparum. Nature (2010) 5.52
Modeling biomedical experimental processes with OBI. J Biomed Semantics (2010) 5.36
Promoter features related to tissue specificity as measured by Shannon entropy. Genome Biol (2005) 5.19
PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale. Genes Dev (2008) 4.83
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature (2006) 4.80
The Plasmodium genome database. Nature (2002) 4.36
Creating a honey bee consensus gene set. Genome Biol (2007) 4.17
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Predicting gene ontology functions from ProDom and CDD protein domains. Genome Res (2002) 4.06
The genome of Cryptosporidium hominis. Nature (2004) 3.93
Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast. Nat Rev Microbiol (2004) 3.85
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
Development of FuGO: an ontology for functional genomics investigations. OMICS (2006) 3.59
The Functional Genomics Experiment model (FuGE): an extensible framework for standards in functional genomics. Nat Biotechnol (2007) 3.55
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ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24
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Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum. Science (2003) 3.08
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. J Cell Biol (2009) 3.04
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CryptoDB: a Cryptosporidium bioinformatics resource update. Nucleic Acids Res (2006) 2.68
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res (2005) 2.64
Defining the mammalian CArGome. Genome Res (2005) 2.59
Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov (2008) 2.58
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ApiDB: integrated resources for the apicomplexan bioinformatics resource center. Nucleic Acids Res (2006) 2.37
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GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis. Nucleic Acids Res (2008) 2.35