PubRank

Jorge E Galán

Author PubWeight™ 131.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006 10.58
2 IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002 6.79
3 RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 2002 5.95
4 Unique features of a highly pathogenic Campylobacter jejuni strain. Infect Immun 2006 5.21
5 Chaperone release and unfolding of substrates in type III secretion. Nature 2005 4.21
6 Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity 2006 4.02
7 Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med 2006 3.76
8 Structural insights into the assembly of the type III secretion needle complex. Science 2004 3.49
9 Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proc Natl Acad Sci U S A 2006 2.75
10 Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell 2003 2.60
11 Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature 2011 2.44
12 Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment. Cell Host Microbe 2008 2.26
13 Differential activation and function of Rho GTPases during Salmonella-host cell interactions. J Cell Biol 2006 2.22
14 Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry. Curr Opin Microbiol 2005 2.19
15 A sorting platform determines the order of protein secretion in bacterial type III systems. Science 2011 2.16
16 Assembly of the inner rod determines needle length in the type III secretion injectisome. Nature 2006 2.15
17 A Salmonella protein causes macrophage cell death by inducing autophagy. J Cell Biol 2003 2.15
18 Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science 2004 2.06
19 Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci U S A 2004 1.99
20 Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization. Cell Host Microbe 2008 1.79
21 Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. PLoS Pathog 2009 1.73
22 A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases. Proc Natl Acad Sci U S A 2009 1.70
23 Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cells. Infect Immun 2009 1.68
24 Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J 2002 1.64
25 Diversification of a Salmonella virulence protein function by ubiquitin-dependent differential localization. Cell 2009 1.61
26 Salmonella type III secretion-associated chaperones confer secretion-pathway specificity. Mol Microbiol 2004 1.61
27 Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system. J Virol 2003 1.60
28 Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. PLoS Pathog 2008 1.59
29 Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol 2002 1.55
30 Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system. Mol Microbiol 2011 1.48
31 A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science 2012 1.48
32 Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cells. J Bacteriol 2002 1.47
33 Synthesis and localization of the Salmonella SPI-1 type III secretion needle complex proteins PrgI and PrgJ. J Bacteriol 2003 1.46
34 A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe 2010 1.46
35 In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines. J Clin Invest 2006 1.41
36 Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella. Proc Natl Acad Sci U S A 2011 1.39
37 Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature 2013 1.37
38 Salmonella-induced macrophage death: multiple mechanisms, different outcomes. Cell Microbiol 2004 1.35
39 Topology and organization of the Salmonella typhimurium type III secretion needle complex components. PLoS Pathog 2010 1.32
40 Molecular and functional analysis of the type III secretion signal of the Salmonella enterica InvJ protein. Mol Microbiol 2002 1.32
41 Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells. Infect Immun 2010 1.30
42 Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. PLoS Pathog 2009 1.29
43 The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Mol Microbiol 2004 1.27
44 Host-pathogen interactions: a diversity of themes, a variety of molecular machines. Curr Opin Microbiol 2005 1.26
45 Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases. Curr Opin Microbiol 2009 1.23
46 Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol 2005 1.21
47 A MyD88-deficient mouse model reveals a role for Nramp1 in Campylobacter jejuni infection. Infect Immun 2006 1.17
48 Priming virulence factors for delivery into the host. Nat Rev Mol Cell Biol 2003 1.16
49 Genetic analysis of the Salmonella enterica type III secretion-associated ATPase InvC defines discrete functional domains. J Bacteriol 2004 1.15
50 Organization and coordinated assembly of the type III secretion export apparatus. Proc Natl Acad Sci U S A 2010 1.13
51 The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin. Nat Struct Biol 2002 1.13
52 Disruption of type III secretion in Salmonella enterica serovar Typhimurium by external guide sequences. Nucleic Acids Res 2004 1.07
53 Energizing type III secretion machines: what is the fuel? Nat Struct Mol Biol 2008 1.06
54 The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends Pharmacol Sci 2005 1.06
55 Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. PLoS Pathog 2012 1.03
56 Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation. Cell Host Microbe 2011 1.02
57 InvB is a type III secretion-associated chaperone for the Salmonella enterica effector protein SopE. J Bacteriol 2003 1.02
58 Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors. Nat Rev Microbiol 2013 1.00
59 Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system. Vaccine 2006 1.00
60 Optimization of the delivery of heterologous proteins by the Salmonella enterica serovar Typhimurium type III secretion system for vaccine development. Infect Immun 2006 0.97
61 Immune response to Salmonella: location, location, location? Immunity 2002 0.95
62 A novel pathway for exotoxin delivery by an intracellular pathogen. Curr Opin Microbiol 2008 0.94
63 Identification of a transcriptional regulator that controls intracellular gene expression in Salmonella Typhi. Mol Microbiol 2007 0.93
64 Investigating the function of Rho family GTPases during Salmonella/host cell interactions. Methods Enzymol 2008 0.92
65 A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion. EMBO Rep 2012 0.92
66 The inner rod protein controls substrate switching and needle length in a Salmonella type III secretion system. Proc Natl Acad Sci U S A 2013 0.90
67 Salmonella modulation of host cell gene expression promotes its intracellular growth. PLoS Pathog 2013 0.89
68 Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery. Nat Commun 2013 0.87
69 Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector. Blood 2007 0.83
70 Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model. PLoS One 2012 0.83
71 Characterization of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infect Immun 2009 0.82
72 Cre reporter system to monitor the translocation of type III secreted proteins into host cells. Infect Immun 2006 0.79
73 A new twist in the hijacking of the actin-nucleating machinery. Mol Cell 2004 0.75