Published in Curr Top Med Chem on February 01, 2002
Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res (2007) 1.11
Neurotoxins: free radical mechanisms and melatonin protection. Curr Neuropharmacol (2010) 0.97
Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats. World J Gastroenterol (2008) 0.89
Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide. World J Gastroenterol (2004) 0.88
Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. Dig Dis Sci (2010) 0.87
Hepatoprotective actions of melatonin: possible mediation by melatonin receptors. World J Gastroenterol (2010) 0.87
Reactive oxygen species and the hypomotility of the gall bladder as targets for the treatment of gallstones with melatonin: a review. Dig Dis Sci (2008) 0.78
Prevalence of β(S)-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil. Genet Mol Biol (2015) 0.75
The Incremental Induction of Neuroprotective Properties by Multiple Therapeutic Strategies for Primary and Secondary Neural Injury. Int J Mol Sci (2015) 0.75
Gut melatonin response to microbial infection in carp Catla catla. Fish Physiol Biochem (2015) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res (2004) 2.87
One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species? J Pineal Res (2007) 2.84
Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res (2011) 2.12
Melatonin: from basic research to cancer treatment clinics. J Clin Oncol (2002) 1.99
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem (2002) 1.75
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK. J Pineal Res (2012) 1.60
A review of the multiple actions of melatonin on the immune system. Endocrine (2005) 1.55
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis (2005) 1.52
Melatonin membrane receptors in peripheral tissues: distribution and functions. Mol Cell Endocrinol (2012) 1.47
Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res (2008) 1.40
Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci (2014) 1.31
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res (2009) 1.29
Melatonin and the ovary: physiological and pathophysiological implications. Fertil Steril (2008) 1.29
Melatonin mitigates mitochondrial malfunction. J Pineal Res (2005) 1.27
Causes of oxidative stress in the pre- and perinatal period. Biol Neonate (2002) 1.26
Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys (2004) 1.25
Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin. J Pineal Res (2003) 1.23
A review of the molecular aspects of melatonin's anti-inflammatory actions: recent insights and new perspectives. J Pineal Res (2012) 1.21
Melatonin-immune system relationships. Curr Top Med Chem (2002) 1.21
Oxidative stress of the newborn in the pre- and postnatal period and the clinical utility of melatonin. J Pineal Res (2008) 1.21
Melatonin and mitochondrial function. Life Sci (2004) 1.20
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res (2014) 1.20
Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling. J Pineal Res (2011) 1.20
Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies. J Pineal Res (2011) 1.19
Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science. J Exp Bot (2011) 1.19
Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations. J Pineal Res (2011) 1.18
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance. FASEB J (2004) 1.17
Melatonin and pregnancy in the human. Reprod Toxicol (2008) 1.17
Defining chronodisruption. J Pineal Res (2009) 1.17
Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes. J Pineal Res (2012) 1.15
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J Neuroimmunol (2005) 1.14
Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats. J Pineal Res (2007) 1.11
Cardiovascular diseases: protective effects of melatonin. J Pineal Res (2008) 1.10
Shift work and cancer: the evidence and the challenge. Dtsch Arztebl Int (2010) 1.10
Phytomelatonin: a review. J Exp Bot (2008) 1.09
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism. Prostate (2005) 1.08
Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. Toxicol Lett (2007) 1.08
Chronodisruption and cancer. Naturwissenschaften (2008) 1.08
Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J Pineal Res (2007) 1.07
Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1. FASEB J (2003) 1.07
The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. J Pineal Res (2013) 1.07
Mechanisms of cancer inhibition by melatonin. J Pineal Res (2004) 1.06
Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem (2011) 1.06
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06
Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J Pineal Res (2004) 1.05
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res (2010) 1.04
Melatonin as an antioxidant: physiology versus pharmacology. J Pineal Res (2005) 1.03
Melatonin: an established antioxidant worthy of use in clinical trials. Mol Med (2008) 1.03
Role of melatonin in metabolic regulation. Rev Endocr Metab Disord (2009) 1.03
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp Dermatol (2008) 1.03
Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J Pineal Res (2010) 1.02
Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. FASEB J (2013) 1.02
Melatonin and circadian biology in human cardiovascular disease. J Pineal Res (2010) 1.01
The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. J Pineal Res (2010) 1.01
Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review. Expert Opin Ther Targets (2013) 1.00
A generalized theory of carcinogenesis due to chronodisruption. Neuro Endocrinol Lett (2008) 1.00
Stress response and procedural pain in the preterm newborn: the role of pharmacological and non-pharmacological treatments. Eur J Pediatr (2011) 1.00
Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. Cell Mol Biol Lett (2003) 0.99
Light, timing of biological rhythms, and chronodisruption in man. Naturwissenschaften (2003) 0.99
The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness. Biol Rev Camb Philos Soc (2009) 0.99
Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep (2003) 0.98
Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age. J Gerontol A Biol Sci Med Sci (2009) 0.98
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. J Pineal Res (2013) 0.98
Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin. Am J Perinatol (2004) 0.98
Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells. J Pineal Res (2010) 0.97
Melatonin: potential functions in the oral cavity. J Periodontol (2007) 0.97
Pain in neonatal intensive care: role of melatonin as an analgesic antioxidant. J Pineal Res (2011) 0.97
Melatonin counteracts inducible mitochondrial nitric oxide synthase-dependent mitochondrial dysfunction in skeletal muscle of septic mice. J Pineal Res (2006) 0.97
Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells. J Pineal Res (2009) 0.96
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection. J Pineal Res (2007) 0.96
Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms. J Pineal Res (2010) 0.96
Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. J Plant Physiol (2008) 0.96
Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB J (2007) 0.95
Pharmacokinetics of orally administered melatonin in critically ill patients. J Pineal Res (2010) 0.95
Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells. J Pineal Res (2010) 0.95
Exercise and melatonin in humans: reciprocal benefits. J Pineal Res (2011) 0.95
Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro. J Pineal Res (2003) 0.95
Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin. J Pineal Res (2011) 0.95
Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine. J Pineal Res (2013) 0.94
Protective effects of melatonin in experimental free radical-related ocular diseases. J Pineal Res (2006) 0.94
SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy (2015) 0.94
The role of the thalamus in sleep, pineal melatonin production, and circadian rhythm sleep disorders. J Pineal Res (2008) 0.94
Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation. J Membr Biol (2010) 0.93
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice. J Pineal Res (2014) 0.93
INDOLE-3-ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin-mediated pathway in Arabidopsis. J Pineal Res (2014) 0.93
The modulatory role of melatonin on immune responsiveness. Curr Opin Investig Drugs (2006) 0.93
Melatonin and Parkinson's disease. Endocrine (2005) 0.93
Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical. J Pineal Res (2003) 0.93
Changes in melatonin levels in transgenic 'Micro-Tom' tomato overexpressing ovine AANAT and ovine HIOMT genes. J Pineal Res (2013) 0.93
A review of metal-catalyzed molecular damage: protection by melatonin. J Pineal Res (2014) 0.92
Epigenetic regulation: a new research area for melatonin? J Pineal Res (2008) 0.92
Clinical uses of melatonin in pediatrics. Int J Pediatr (2011) 0.91
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. J Neurochem (2006) 0.91
Correlation among cytokines, bronchopulmonary dysplasia and modality of ventilation in preterm newborns: improvement with melatonin treatment. J Pineal Res (2005) 0.91
A review of melatonin as a suitable antioxidant against myocardial ischemia-reperfusion injury and clinical heart diseases. J Pineal Res (2014) 0.91
Purslane: a plant source of omega-3 fatty acids and melatonin. J Pineal Res (2005) 0.91
Accumulation of exogenous amyloid-beta peptide in hippocampal mitochondria causes their dysfunction: a protective role for melatonin. Oxid Med Cell Longev (2012) 0.91