Published in Chembiochem on April 02, 2002
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A (2007) 9.82
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res (2005) 8.69
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Mol Cell Biol (2005) 3.05
Epigenetic modifications in pluripotent and differentiated cells. Nat Biotechnol (2010) 3.02
Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr (2006) 2.83
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression. J Biol Chem (2003) 2.15
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J (2006) 2.07
MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer (2009) 1.88
Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism. RNA (2008) 1.76
Importance of methyl donors during reproduction. Am J Clin Nutr (2008) 1.62
Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism. Mol Microbiol (2010) 1.56
Epigenetic alterations in human prostate cancers. Endocrinology (2009) 1.55
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Res (2008) 1.46
To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems. Nucleic Acids Res (2013) 1.42
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase. Nucleic Acids Res (2006) 1.36
Characterization of cytosine methylated regions and 5-cytosine DNA methyltransferase (Ehmeth) in the protozoan parasite Entamoeba histolytica. Nucleic Acids Res (2004) 1.36
Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy. Cancer Gene Ther (2005) 1.34
MmeI: a minimal Type II restriction-modification system that only modifies one DNA strand for host protection. Nucleic Acids Res (2008) 1.33
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J Biol Chem (2006) 1.33
Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr Med Chem (2010) 1.30
Epigenetic mechanisms for nutrition determinants of later health outcomes. Am J Clin Nutr (2009) 1.28
Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase. J Mol Biol (2006) 1.27
Perinatal choline influences brain structure and function. Nutr Rev (2006) 1.26
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth. Prostate (2010) 1.25
Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. Biol Psychiatry (2012) 1.24
Extrahelical damaged base recognition by DNA glycosylase enzymes. Chemistry (2008) 1.19
The fetal origins of memory: the role of dietary choline in optimal brain development. J Pediatr (2006) 1.19
Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis. J Clin Invest (2014) 1.18
Homology-dependent methylation in primate repetitive DNA. Proc Natl Acad Sci U S A (2005) 1.13
On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2. PLoS One (2011) 1.13
Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models. Brain Res (2008) 1.11
Structure, function and mechanism of exocyclic DNA methyltransferases. Biochem J (2006) 1.07
Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. J Biol Chem (2006) 1.06
MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma. Mol Cancer (2011) 1.05
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB Life (2007) 1.03
Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline. Am J Clin Nutr (2007) 1.01
Molecular and enzymatic profiles of mammalian DNA methyltransferases: structures and targets for drugs. Curr Med Chem (2010) 0.99
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2. Proc Natl Acad Sci U S A (2009) 0.99
Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells. Mol Autism (2013) 0.98
The functions of DNA methylation by CcrM in Caulobacter crescentus: a global approach. Nucleic Acids Res (2014) 0.98
Direct detection of methylation in genomic DNA. Nucleic Acids Res (2005) 0.97
Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells. Int Immunol (2010) 0.97
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC). RNA (2009) 0.94
An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function. Epigenetics (2012) 0.92
Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor. Adv Protein Chem Struct Biol (2012) 0.91
Evolving insights on how cytosine methylation affects protein-DNA binding. Brief Funct Genomics (2014) 0.90
The chloroplast genomes of Bryopsis plumosa and Tydemania expeditiones (Bryopsidales, Chlorophyta): compact genomes and genes of bacterial origin. BMC Genomics (2015) 0.89
Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry (CCMS). J Vis Exp (2010) 0.89
Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates. Appl Environ Microbiol (2006) 0.88
Enhanced transformation efficiency of recalcitrant Bacillus cereus and Bacillus weihenstephanensis isolates upon in vitro methylation of plasmid DNA. Appl Environ Microbiol (2008) 0.88
Electrochemical assay for the signal-on detection of human DNA methyltransferase activity. J Am Chem Soc (2013) 0.87
The supply of choline is important for fetal progenitor cells. Semin Cell Dev Biol (2011) 0.87
Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome. Free Radic Biol Med (2012) 0.85
A comparative categorization of protein function encoded in bacterial or archeal genomic islands. J Mol Evol (2005) 0.84
A real-time assay for CpG-specific cytosine-C5 methyltransferase activity. Nucleic Acids Res (2010) 0.84
Nontypeable Haemophilus influenzae genetic islands associated with chronic pulmonary infection. PLoS One (2012) 0.84
Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs. PLoS One (2013) 0.84
Clinical significance of the interaction between non-coding RNAs and the epigenetics machinery: challenges and opportunities in oncology. Epigenetics (2013) 0.83
Comparative transcriptomics of H. pylori strains AM5, SS1 and their hpyAVIBM deletion mutants: possible roles of cytosine methylation. PLoS One (2012) 0.83
Dimerization of the bacterial RsrI N6-adenine DNA methyltransferase. Nucleic Acids Res (2006) 0.83
DNA cytosine methylation: structural and thermodynamic characterization of the epigenetic marking mechanism. Biochemistry (2013) 0.83
Pharmacodynamic study of disulfiram in men with non-metastatic recurrent prostate cancer. Prostate Cancer Prostatic Dis (2013) 0.83
Protein and nucleic acid methylating enzymes: mechanisms and regulation. Curr Opin Chem Biol (2012) 0.82
DNA methylation changes between relapse and remission of minimal change nephrotic syndrome. Pediatr Nephrol (2012) 0.82
The N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase PrmC/HemK in Chlamydia trachomatis methylates class 1 release factors. J Bacteriol (2005) 0.82
Epigenetic regulation of adipocyte differentiation by a Rho guanine nucleotide exchange factor, WGEF. PLoS One (2009) 0.82
The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu. Nucleic Acids Res (2014) 0.82
Cytosine methylation is not the major factor inducing CpG dinucleotide deficiency in bacterial genomes. J Mol Evol (2004) 0.82
Complementation between inactive fragments of SssI DNA methyltransferase. BMC Mol Biol (2012) 0.81
The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner. Nucleic Acids Res (2011) 0.81
Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695. PLoS One (2011) 0.81
In vivo DNA protection by relaxed-specificity SinI DNA methyltransferase variants. J Bacteriol (2008) 0.80
Differential stabilization of reaction intermediates: specificity checkpoints for M.EcoRI revealed by transient fluorescence and fluorescence lifetime studies. Nucleic Acids Res (2008) 0.80
Prostate cancer epigenetics and its clinical implications. Asian J Androl (2016) 0.80
Dnmt3a-CD is less susceptible to bulky benzo[a]pyrene diol epoxide-derived DNA lesions than prokaryotic DNA methyltransferases. Biochemistry (2011) 0.80
Prediction of Plant Height in Arabidopsis thaliana Using DNA Methylation Data. Genetics (2015) 0.80
DNA Methylation in Basal Metazoans: Insights from Ctenophores. Integr Comp Biol (2015) 0.80
Symmetry elements in DNA structure important for recognition/methylation by DNA [amino]-methyltransferases. Nucleic Acids Res (2004) 0.79
Kinetic analysis of Yersinia pestis DNA adenine methyltransferase activity using a hemimethylated molecular break light oligonucleotide. PLoS One (2007) 0.79
Rationalization of activity cliffs of a sulfonamide inhibitor of DNA methyltransferases with induced-fit docking. Int J Mol Sci (2014) 0.78
Structure analysis of Entamoeba histolytica DNMT2 (EhMeth). PLoS One (2012) 0.78
The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols. BMC Biochem (2011) 0.78
DNA methyltransferase 1 mutations and mitochondrial pathology: is mtDNA methylated? Front Genet (2015) 0.78
DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications. Adv Exp Med Biol (2016) 0.78
Decreased DNA Methylations at the Progesterone Receptor Promoter A Induce Functional Progesterone Withdrawal in Human Parturition. Reprod Sci (2014) 0.77
Daily variation in global and local DNA methylation in mouse livers. PLoS One (2015) 0.77
Homology modeling and molecular dynamics simulations of HgiDII methyltransferase in complex with DNA and S-adenosyl-methionine: catalytic mechanism and interactions with DNA. J Mol Model (2009) 0.77
Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis. Arterioscler Thromb Vasc Biol (2015) 0.77
Expression, crystallization and preliminary X-ray diffraction analysis of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.76
Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm. Nucleic Acids Res (2016) 0.76
Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates. J Biol Chem (2016) 0.76
Novel Methyltransferase Recognition Motif Identified in Chania multitudinisentens RB-25(T) gen. nov., sp. nov. Front Microbiol (2016) 0.75
Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis. Wiley Interdiscip Rev Syst Biol Med (2016) 0.75
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions. BMC Bioinformatics (2006) 0.75
Expression profiling and clinicopathological significance of DNA methyltransferase 1, 3A and 3B in sporadic human renal cell carcinoma. Int J Clin Exp Pathol (2014) 0.75
Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity. BMC Biochem (2016) 0.75
Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis. Acta Biochim Biophys Sin (Shanghai) (2015) 0.75