Published in FASEB J on January 01, 2006
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes. J Exp Med (2008) 2.79
The Emerging Hallmarks of Cancer Metabolism. Cell Metab (2016) 2.32
Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation. J Nutr Biochem (2012) 1.65
Importance of methyl donors during reproduction. Am J Clin Nutr (2008) 1.62
Choline and betaine in health and disease. J Inherit Metab Dis (2010) 1.61
Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder. J Psychiatr Res (2011) 1.57
Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr (2010) 1.51
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS One (2017) 1.39
Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology (2011) 1.34
Gene-environment interactions and epigenetic basis of human diseases. Curr Issues Mol Biol (2008) 1.31
Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. Neurotoxicol Teratol (2009) 1.30
Epigenetic mechanisms for nutrition determinants of later health outcomes. Am J Clin Nutr (2009) 1.28
Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administration. Brain Res (2008) 1.27
Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia. Front Integr Neurosci (2008) 1.26
Diet and the epigenetic (re)programming of phenotypic differences in behavior. Brain Res (2008) 1.22
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain. J Biol Chem (2008) 1.21
Epigenetic modifications: basic mechanisms and role in cardiovascular disease. Circulation (2011) 1.20
DNA methylation impacts on learning and memory in aging. Neurobiol Aging (2007) 1.20
A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism. Am J Med Genet B Neuropsychiatr Genet (2010) 1.19
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol (2012) 1.17
Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. Birth Defects Res A Clin Mol Teratol (2010) 1.17
Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models. Brain Res (2008) 1.11
Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children. Sci Rep (2016) 1.10
Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc Natl Acad Sci U S A (2010) 1.09
The emerging role of epigenetic mechanisms in the etiology of neural tube defects. Epigenetics (2011) 1.08
Choline supplementation mitigates trace, but not delay, eyeblink conditioning deficits in rats exposed to alcohol during development. Hippocampus (2011) 1.05
High fat diet-induced maternal obesity alters fetal hippocampal development. Int J Dev Neurosci (2009) 1.05
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB Life (2007) 1.03
Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals. Ann N Y Acad Sci (2013) 1.02
Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline. Am J Clin Nutr (2007) 1.01
The effects of perinatal choline supplementation on hippocampal cholinergic development in rats exposed to alcohol during the brain growth spurt. Hippocampus (2012) 1.00
Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS One (2012) 1.00
Folate intake at RDA levels is inadequate for Mexican American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr (2008) 1.00
Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. Alcohol Clin Exp Res (2013) 1.00
Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol Dis (2008) 0.99
Choline supplementation and DNA methylation in the hippocampus and prefrontal cortex of rats exposed to alcohol during development. Alcohol Clin Exp Res (2012) 0.98
Nutritional genomics: defining the dietary requirement and effects of choline. J Nutr (2011) 0.98
Adequate Intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load. Am J Clin Nutr (2008) 0.97
Fetal stress and programming of hypoxic/ischemic-sensitive phenotype in the neonatal brain: mechanisms and possible interventions. Prog Neurobiol (2012) 0.97
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutr Neurosci (2009) 0.95
Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones. Mutat Res (2011) 0.95
Epigenetic programming of the rRNA promoter by MBD3. Mol Cell Biol (2007) 0.95
Epigenetic dysregulation of the dopamine system in diet-induced obesity. J Neurochem (2012) 0.95
Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter. Lipids Health Dis (2013) 0.95
Choline intake during pregnancy and child cognition at age 7 years. Am J Epidemiol (2013) 0.94
Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism. J Autism Dev Disord (2008) 0.94
Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neurobiol Dis (2013) 0.93
Metabolomic profiling in blood from umbilical cords of low birth weight newborns. J Transl Med (2012) 0.93
DNA methylation-mediated control of learning and memory. Mol Brain (2011) 0.92
Individual differences in novelty seeking predict subsequent vulnerability to social defeat through a differential epigenetic regulation of brain-derived neurotrophic factor expression. J Neurosci (2013) 0.92
Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice. Neurobiol Dis (2014) 0.91
DNA methylation program in developing hippocampus and its alteration by alcohol. PLoS One (2013) 0.91
What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. Mol Neurobiol (2011) 0.90
Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse. J Biol Chem (2009) 0.90
Choline nutrition programs brain development via DNA and histone methylation. Cent Nerv Syst Agents Med Chem (2012) 0.89
Dietary choline and betaine intakes and risk of cardiovascular diseases: review of epidemiological evidence. ARYA Atheroscler (2011) 0.89
Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr (2010) 0.87
Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study. BMC Med Genet (2007) 0.87
Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis. Clin Chem Lab Med (2013) 0.87
The supply of choline is important for fetal progenitor cells. Semin Cell Dev Biol (2011) 0.87
Obesogenic phenotype of offspring of dams fed a high multivitamin diet is prevented by a post-weaning high multivitamin or high folate diet. Int J Obes (Lond) (2013) 0.86
Epigenetic medicine and fetal alcohol spectrum disorders. Epigenomics (2013) 0.86
Betaine supplementation attenuates atherosclerotic lesion in apolipoprotein E-deficient mice. Eur J Nutr (2009) 0.86
Alzheimer's disease and environmental exposure to lead: the epidemiologic evidence and potential role of epigenetics. Curr Alzheimer Res (2012) 0.86
Choline's role in maintaining liver function: new evidence for epigenetic mechanisms. Curr Opin Clin Nutr Metab Care (2013) 0.85
Perinatal choline deficiency produces abnormal sensory inhibition in Sprague-Dawley rats. Brain Res (2008) 0.84
Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not. Am J Clin Nutr (2007) 0.84
Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Res (2007) 0.83
The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates. Nutrients (2014) 0.83
Excess of methyl donor in the perinatal period reduces postnatal leptin secretion in rat and interacts with the effect of protein content in diet. PLoS One (2013) 0.82
Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements. J Nutrigenet Nutrigenomics (2011) 0.82
The impact of nutrition on differential methylated regions of the genome. Adv Nutr (2011) 0.82
Maternal α-linolenic acid availability during gestation and lactation alters the postnatal hippocampal development in the mouse offspring. Int J Dev Neurosci (2011) 0.82
Considering maternal dietary modulators for epigenetic regulation and programming of the fetal epigenome. Nutrients (2015) 0.82
Analysis of epigenetic factors in mouse embryonic neural stem cells exposed to hyperglycemia. PLoS One (2013) 0.81
Diet-gene interactions underlie metabolic individuality and influence brain development: implications for clinical practice derived from studies on choline metabolism. Ann Nutr Metab (2012) 0.81
Diethanolamine alters proliferation and choline metabolism in mouse neural precursor cells. Toxicol Sci (2007) 0.81
Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood. Nutrients (2015) 0.81
Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J (2008) 0.80
Neuroprotective actions of perinatal choline nutrition. Clin Chem Lab Med (2013) 0.80
Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus. Am J Physiol Regul Integr Comp Physiol (2014) 0.80
Frontiers in research on maternal diabetes-induced neural tube defects: Past, present and future. World J Diabetes (2012) 0.80
Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2. PLoS One (2013) 0.79
Dietary intake and plasma levels of choline and betaine in children with autism spectrum disorders. Autism Res Treat (2013) 0.79
An epigenetic hypothesis for the genomic memory of pain. Front Cell Neurosci (2015) 0.79
Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease. Curr Alzheimer Res (2016) 0.78
Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro. Eur J Nutr (2012) 0.78
Transgenerational inheritance of metabolic disease. Semin Cell Dev Biol (2015) 0.78
Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome. Curr Alzheimer Res (2016) 0.77
Protein content and methyl donors in maternal diet interact to influence the proliferation rate and cell fate of neural stem cells in rat hippocampus. Nutrients (2014) 0.76
Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. FASEB J (2015) 0.76
Adult emotionality and neural plasticity as a function of adolescent nutrient supplementation in male rats. Pharmacol Biochem Behav (2015) 0.76
Characterization of choline transporters in the human placenta over gestation. Placenta (2015) 0.75
Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents. FASEB J (2016) 0.75
Longitudinal effects of developmental bisphenol A and variable diet exposures on epigenetic drift in mice. Reprod Toxicol (2016) 0.75
From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and Disease. Int J Biol Sci (2016) 0.75
Effects of Choline on Meat Quality and Intramuscular Fat in Intrauterine Growth Retardation Pigs. PLoS One (2015) 0.75
MethPrimer: designing primers for methylation PCRs. Bioinformatics (2002) 14.48
The regulation of E2F by pRB-family proteins. Genes Dev (1998) 12.77
Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol (2003) 9.30
Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol (2002) 5.86
G1 cell-cycle control and cancer. Nature (2004) 5.72
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr (2002) 4.97
DNA methylation in health and disease. Nat Rev Genet (2000) 4.58
Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases. Chembiochem (2002) 3.15
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Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods. J Comp Neurol (1990) 3.03
Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Mol Cell Neurosci (2003) 2.33
Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan. Neurosci Biobehav Rev (2003) 2.10
Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain Res Dev Brain Res (1999) 1.90
Pathways and regulation of homocysteine metabolism in mammals. Semin Thromb Hemost (2000) 1.75
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr (2003) 1.73
Pre- and postnatal choline supplementation produces long-term facilitation of spatial memory. Dev Psychobiol (1988) 1.72
Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain Res Dev Brain Res (1999) 1.65
KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases. Proc Natl Acad Sci U S A (1994) 1.45
Perinatal choline supplementation increases the threshold for chunking in spatial memory. Neuroreport (1997) 1.44
Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res (2001) 1.40
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
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Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus. Dev Neurosci (2001) 1.15
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Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci (2003) 1.10
Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Res Mol Brain Res (2004) 1.04
Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus. Epilepsy Res (2002) 1.04
Choline deficiency induces apoptosis in primary cultures of fetal neurons. FASEB J (2001) 1.02
Protective effects of prenatal choline supplementation on seizure-induced memory impairment. J Neurosci (2000) 1.01
Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochem Res (1998) 0.99
Structure-based design of cyclin-dependent kinase inhibitors. Pharmacol Ther (2002) 0.96
Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells. J Nutr (2002) 0.95
Perinatal choline treatment modifies the effects of a visuo-spatial attractive cue upon spatial memory in naive adult rats. Brain Res (2002) 0.91
Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma. Cancer Lett (2004) 0.87
Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry. Anal Chem (2002) 2.35
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J (2005) 2.34
Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J Nutr (2002) 2.33
Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency. Gastroenterology (2010) 2.30
Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst (2007) 2.07
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88
Common genetic polymorphisms affect the human requirement for the nutrient choline. FASEB J (2006) 1.88
Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr (2007) 1.76
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci U S A (2005) 1.73
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr (2003) 1.73
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71
Evidence-based criteria in the nutritional context. Nutr Rev (2010) 1.68
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. Am J Clin Nutr (2005) 1.66
Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Am J Clin Nutr (2002) 1.60
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. FASEB J (2003) 1.59
Diethanolamine induces hepatic choline deficiency in mice. Toxicol Sci (2002) 1.57
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria. J Am Diet Assoc (2004) 1.53
Choline metabolism and risk of breast cancer in a population-based study. FASEB J (2008) 1.51
Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus. FASEB J (2006) 1.47
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord (2007) 1.47
Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts. Am J Clin Nutr (2004) 1.46
Nutrition education in U.S. medical schools: latest update of a national survey. Acad Med (2010) 1.42
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. FASEB J (2002) 1.41
Status of nutrition education in medical schools. Am J Clin Nutr (2006) 1.41
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem (2011) 1.40
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. J Nutr (2003) 1.36
Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. J Nutr (2004) 1.35
Second trimester folate status and preterm birth. Am J Obstet Gynecol (2004) 1.32
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr (2002) 1.19
Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. FASEB J (2010) 1.18
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. Am J Clin Nutr (2006) 1.18
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol (2012) 1.17
BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Res Treat (2008) 1.16
Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr J (2009) 1.16
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr (2007) 1.16
Nutrition in medicine: nutrition education for medical students and residents. Nutr Clin Pract (2010) 1.14
Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci (2003) 1.10
Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. J Nutr (2005) 1.10
Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc Natl Acad Sci U S A (2010) 1.09
The role of dietary supplements during cancer therapy. J Nutr (2003) 1.09
Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus. Brain Res Dev Brain Res (2005) 1.06
Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutr Cancer (2004) 1.06
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cell Physiol Biochem (2005) 1.05
Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Res Mol Brain Res (2004) 1.04
Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. J Biol Chem (2010) 1.04
Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. J Nutr Biochem (2006) 1.04
GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans. J Nutr (2007) 1.03
Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol (2002) 1.01
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J (2013) 1.00
High intakes of choline and betaine reduce breast cancer mortality in a population-based study. FASEB J (2009) 0.99
Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J (2010) 0.99
Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes. J Cell Biochem (2003) 0.99
Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. Am J Clin Nutr (2010) 0.99
Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students. Am J Clin Nutr (2002) 0.98
Perinatal manipulation of α-linolenic acid intake induces epigenetic changes in maternal and offspring livers. FASEB J (2012) 0.98
Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. Am J Clin Nutr (2003) 0.98
Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes (2005) 0.96
Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells. J Nutr (2002) 0.95
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum. Am J Clin Nutr (2006) 0.95
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutr Neurosci (2009) 0.95
Adiponectin lowers glucose production by increasing SOGA. Am J Pathol (2010) 0.94
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. Brain Res Dev Brain Res (2004) 0.94
Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr (2010) 0.92
Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr (2012) 0.92
Mouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissue. J Biol Chem (2012) 0.92
Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD). Neurotoxicol Teratol (2013) 0.92
The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic. Toxicol Appl Pharmacol (2012) 0.91
Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. Am J Clin Nutr (2011) 0.91
Choline and betaine intake and the risk of colorectal cancer in men. Cancer Epidemiol Biomarkers Prev (2010) 0.90
Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res (2013) 0.90
Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse. J Biol Chem (2009) 0.90
Adapting the contents of computer-based instruction based on knowledge tests maintains effectiveness of nutrition education. Am J Clin Nutr (2003) 0.88
A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids. Metabolomics (2013) 0.88
Choline dehydrogenase polymorphism rs12676 is a functional variation and is associated with changes in human sperm cell function. PLoS One (2012) 0.87
Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr (2010) 0.87
Perspectives from the symposium: The role of nutrition in infant and toddler brain and behavioral development. Nutr Neurosci (2008) 0.85
Choline's role in maintaining liver function: new evidence for epigenetic mechanisms. Curr Opin Clin Nutr Metab Care (2013) 0.85
Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J (2013) 0.85
Are dietary choline and betaine intakes determinants of total homocysteine concentration? Am J Clin Nutr (2010) 0.85
Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake. J Nutr (2012) 0.84
Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not. Am J Clin Nutr (2007) 0.84
Activation of a caspase-dependent oxidative damage response mediates TGFbeta1 apoptosis in rat hepatocytes. Exp Mol Pathol (2003) 0.84
Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial. Menopause (2008) 0.83
Choline intake and risk of lethal prostate cancer: incidence and survival. Am J Clin Nutr (2012) 0.83