Published in Development on April 01, 2002
Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol (2010) 9.35
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature (2010) 8.84
Epigenetic reprogramming in plant and animal development. Science (2010) 5.18
Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature (2008) 4.69
Epigenetic inheritance during the cell cycle. Nat Rev Mol Cell Biol (2009) 4.43
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell (2012) 4.32
Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet (2011) 4.25
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet (2008) 3.89
Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol (2009) 3.12
Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism. Proc Natl Acad Sci U S A (2003) 2.48
Epigenetics and assisted reproductive technology: a call for investigation. Am J Hum Genet (2004) 2.41
Epigenetic programming and reprogramming during development. Nat Struct Mol Biol (2013) 2.13
Paternal transmission of stress-induced pathologies. Biol Psychiatry (2011) 2.07
TET family proteins and their role in stem cell differentiation and transformation. Cell Stem Cell (2011) 1.87
Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res (2012) 1.78
Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci U S A (2003) 1.73
Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice. EMBO J (2012) 1.70
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle (2009) 1.64
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development (2012) 1.55
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm. PLoS One (2007) 1.55
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Genes Dev (2014) 1.55
New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos Trans R Soc Lond B Biol Sci (2013) 1.49
Very small embryonic-like stem cells: characterization, developmental origin, and biological significance. Exp Hematol (2008) 1.35
Recent advancements in cloning by somatic cell nuclear transfer. Philos Trans R Soc Lond B Biol Sci (2013) 1.33
Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming. Cell Res (2011) 1.33
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Res (2013) 1.30
Epigenetics and its role in male infertility. J Assist Reprod Genet (2012) 1.27
Primordial germ cells in mice. Cold Spring Harb Perspect Biol (2012) 1.23
Epiblast/germ line hypothesis of cancer development revisited: lesson from the presence of Oct-4+ cells in adult tissues. Stem Cell Rev (2010) 1.17
Assisted reproduction treatment and epigenetic inheritance. Hum Reprod Update (2012) 1.11
Primordial germ cell specification from embryonic stem cells. PLoS One (2008) 1.09
Adult mice cloned from migrating primordial germ cells. Proc Natl Acad Sci U S A (2005) 1.08
Endocrine disruptors, environmental oxygen, epigenetics and pregnancy. Front Biosci (Elite Ed) (2011) 1.07
Genomic imprinting-an epigenetic gene-regulatory model. Curr Opin Genet Dev (2010) 1.05
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proc Natl Acad Sci U S A (2002) 1.05
Somatic cell nuclear transfer efficiency: how can it be improved through nuclear remodeling and reprogramming? Mol Reprod Dev (2010) 1.02
cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period. Reprod Biol Endocrinol (2004) 1.02
Very small embryonic/epiblast-like stem cells: a missing link to support the germ line hypothesis of cancer development? Am J Pathol (2009) 1.01
Primordial germ cell-like cells differentiated in vitro from skin-derived stem cells. PLoS One (2009) 1.00
Very small embryonic-like stem cells in adult tissues-potential implications for aging. Mech Ageing Dev (2008) 0.99
Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment? Philos Trans R Soc Lond B Biol Sci (2003) 0.96
GADD45A protein plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. J Biol Chem (2011) 0.96
Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment. Lancet Neurol (2013) 0.96
Dynamic nuclear organization of constitutive heterochromatin during fetal male germ cell development in mice. Biol Reprod (2009) 0.95
Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis. Genes Dev (2008) 0.92
Generation of primordial germ cells from pluripotent stem cells. Differentiation (2009) 0.91
5-Hydroxymethylcytosine: a stable or transient DNA modification? Genomics (2014) 0.90
Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX<-->XY chimeric testes. Proc Natl Acad Sci U S A (2005) 0.88
DNA modifications: function and applications in normal and disease States. Biology (Basel) (2014) 0.88
Epigenetic reprogramming in the porcine germ line. BMC Dev Biol (2011) 0.88
Should I stay or should I go: protection and maintenance of DNA methylation at imprinted genes. Epigenetics (2012) 0.88
Role of ART in imprinting disorders. Semin Reprod Med (2012) 0.87
Understanding the X chromosome inactivation cycle in mice: a comprehensive view provided by nuclear transfer. Epigenetics (2013) 0.87
RNA expression microarray analysis in mouse prospermatogonia: identification of candidate epigenetic modifiers. Dev Dyn (2008) 0.86
Active DNA demethylation is required for complete imprint erasure in primordial germ cells. Sci Rep (2014) 0.85
Imprinted gene expression, transplantation medicine, and the "other" human embryonic stem cell. Proc Natl Acad Sci U S A (2002) 0.85
Epigenetic inheritance of metabolic state. Curr Opin Genet Dev (2014) 0.84
Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice. Reprod Biol Endocrinol (2014) 0.84
Imprinting methylation errors in ART. Reprod Med Biol (2014) 0.84
Epigenetic modifications and self-renewal regulation of mouse germline stem cells. Cell Res (2011) 0.83
Chromatin dynamics and Arabidopsis development. Chromosome Res (2003) 0.82
Autonomous silencing of the imprinted Cdkn1c gene in stem cells. Epigenetics (2010) 0.82
Imprinted methylation profiles for proximal mouse chromosomes 11 and 7 as revealed by methylation-sensitive representational difference analysis. Mamm Genome (2003) 0.81
Parallel gateways to pluripotency: open chromatin in stem cells and development. Curr Opin Genet Dev (2010) 0.81
Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development. Philos Trans R Soc Lond B Biol Sci (2013) 0.81
Genomic imprinting and assisted reproduction. Reprod Health (2004) 0.81
Specification and epigenetic programming of the human germ line. Nat Rev Genet (2016) 0.80
Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting. Hum Mol Genet (2014) 0.79
Postnatal epigenetic reprogramming in the germline of a marsupial, the tammar wallaby. Epigenetics Chromatin (2013) 0.77
Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals. Proc Jpn Acad Ser B Phys Biol Sci (2015) 0.77
In quest of genomic treasure. J Reprod Dev (2015) 0.76
High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting. Chromosoma (2014) 0.76
Maternal TET3 is dispensable for embryonic development but is required for neonatal growth. Sci Rep (2015) 0.76
The role of sex chromosomes in mammalian germ cell differentiation: can the germ cells carrying X and Y chromosomes differentiate into fertile oocytes? Asian J Androl (2015) 0.75
Factors associated with aberrant imprint methylation and oligozoospermia. Sci Rep (2017) 0.75
Development of reproductive engineering techniques at the RIKEN BioResource Center. Exp Anim (2016) 0.75
Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors. Genome Res (2016) 0.75
Physiological and pathological implications of 5-hydroxymethylcytosine in diseases. Oncotarget (2016) 0.75
DMRT proteins and coordination of mammalian spermatogenesis. Stem Cell Res (2017) 0.75
Epigenetic regulation during the differentiation of stem cells to germ cells. Oncotarget (2017) 0.75
Long-term proliferation in culture and germline transmission of mouse male germline stem cells. Biol Reprod (2003) 5.32
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
In vitro production of functional sperm in cultured neonatal mouse testes. Nature (2011) 4.73
Generation of pluripotent stem cells from neonatal mouse testis. Cell (2004) 3.95
Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue. Biotechniques (2009) 3.04
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature (2012) 2.38
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science (2010) 2.34
Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet (2006) 2.19
Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nat Genet (2008) 2.16
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat Genet (2008) 2.13
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nat Genet (2005) 2.13
Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions. Biol Reprod (2004) 2.01
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet (2009) 1.96
Serum- and feeder-free culture of mouse germline stem cells. Biol Reprod (2010) 1.81
Akt mediates self-renewal division of mouse spermatogonial stem cells. Development (2007) 1.79
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb. J Hum Genet (2003) 1.72
Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting. PLoS Genet (2007) 1.70
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture. Development (2005) 1.65
Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc Natl Acad Sci U S A (2012) 1.63
Generation of functional oocytes and spermatids from fetal primordial germ cells after ectopic transplantation in adult mice. Biol Reprod (2010) 1.63
Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6. Genome Res (2003) 1.61
Pluripotency of a single spermatogonial stem cell in mice. Biol Reprod (2008) 1.59
Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites. Nucleic Acids Res (2003) 1.54
Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr Biol (2005) 1.49
In vitro production of fertile sperm from murine spermatogonial stem cell lines. Nat Commun (2011) 1.49
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells. Proc Natl Acad Sci U S A (2006) 1.45
Faithful expression of imprinted genes in cloned mice. Science (2002) 1.45
Reconstitution of mouse spermatogonial stem cell niches in culture. Cell Stem Cell (2012) 1.41
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet (2004) 1.40
Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem (2010) 1.37
Restoration of spermatogenesis by lentiviral gene transfer: offspring from infertile mice. Proc Natl Acad Sci U S A (2002) 1.35
RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. Proc Natl Acad Sci U S A (2011) 1.34
Recent advancements in cloning by somatic cell nuclear transfer. Philos Trans R Soc Lond B Biol Sci (2013) 1.33
Regulation of spermatogenesis by testis-specific, cytoplasmic poly(A) polymerase TPAP. Science (2002) 1.27
The origin and evolution of genomic imprinting and viviparity in mammals. Philos Trans R Soc Lond B Biol Sci (2013) 1.27
BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin. In Vitro Cell Dev Biol Anim (2009) 1.25
Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby. Mech Dev (2005) 1.24
Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells. Proc Natl Acad Sci U S A (2007) 1.19
The novel imprinted carboxypeptidase A4 gene ( CPA4) in the 7q32 imprinting domain. Hum Genet (2003) 1.19