Published in Nature on March 24, 2011
Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. Cell Stem Cell (2012) 1.99
Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc Natl Acad Sci U S A (2012) 1.63
In vitro production of fertile sperm from murine spermatogonial stem cell lines. Nat Commun (2011) 1.49
Retinol improves in vitro differentiation of pre-pubertal mouse spermatogonial stem cells into sperm during the first wave of spermatogenesis. PLoS One (2015) 1.44
An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk. Cell (2017) 1.39
Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling. Biol Reprod (2015) 1.39
In vitro spermatogenesis: A long journey to get tails. Spermatogenesis (2012) 0.97
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In vitro sperm production from mouse spermatogonial stem cell lines using an organ culture method. Nat Protoc (2013) 0.94
Testicular tissue cryopreservation in prepubertal male children: an analysis of parental decision-making. Pediatr Blood Cancer (2014) 0.94
The dissection of meiotic chromosome movement in mice using an in vivo electroporation technique. PLoS Genet (2014) 0.93
Concise review: Defining characteristics of mammalian spermatogenic stem cells. Stem Cells (2013) 0.93
Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction. Cell Res (2014) 0.92
Experimental methods to preserve male fertility and treat male factor infertility. Fertil Steril (2015) 0.91
Models of in vitro spermatogenesis. Spermatogenesis (2012) 0.91
Establishment of alternative culture method for spermatogonial stem cells using knockout serum replacement. PLoS One (2013) 0.89
Fruitful progress to fertility: male fertility in the test tube. Nat Med (2011) 0.89
A comprehensive system for generation and evaluation of induced pluripotent stem cells using piggyBac transposition. PLoS One (2014) 0.87
Clinical management of infertile men with nonobstructive azoospermia. Asian J Androl (2015) 0.86
Biotechnological approaches to the treatment of aspermatogenic men. Clinics (Sao Paulo) (2013) 0.85
Renal cells from spermatogonial germline stem cells protect against kidney injury. J Am Soc Nephrol (2013) 0.85
Lentiviral mediated transgenesis by in vivo manipulation of spermatogonial stem cells. PLoS One (2011) 0.85
Xenografting of testicular tissue pieces: 12 years of an in vivo spermatogenesis system. Reproduction (2014) 0.83
Novel concepts in male factor infertility: clinical and laboratory perspectives. J Assist Reprod Genet (2016) 0.83
Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes. Stem Cell Reports (2016) 0.83
Perspectives of germ cell development in vitro in mammals. Anim Sci J (2014) 0.83
Regulation of male sex determination: genital ridge formation and Sry activation in mice. Cell Mol Life Sci (2014) 0.83
Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling. Oncotarget (2015) 0.82
Protein-tyrosine kinase signaling in the biological functions associated with sperm. J Signal Transduct (2012) 0.82
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev (2015) 0.82
Hormone suppression with GnRH antagonist promotes spermatogenic recovery from transplanted spermatogonial stem cells in irradiated cynomolgus monkeys. Andrology (2013) 0.81
Fact or fiction: In vitro spermatogenesis. Spermatogenesis (2012) 0.81
NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia. Cell Death Discov (2015) 0.81
Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture. Proteome Sci (2014) 0.81
Differential gene expression profiling of enriched human spermatogonia after short- and long-term culture. Biomed Res Int (2014) 0.81
Testicular niche required for human spermatogonial stem cell expansion. Stem Cells Transl Med (2014) 0.81
Effects of vitamin A on in vitro maturation of pre-pubertal mouse spermatogonial stem cells. PLoS One (2013) 0.80
Possible therapeutic use of spermatogonial stem cells in the treatment of male infertility: a brief overview. ScientificWorldJournal (2012) 0.80
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo. PLoS One (2015) 0.80
Developments in techniques for the isolation, enrichment, main culture conditions and identification of spermatogonial stem cells. Cytotechnology (2015) 0.79
Sororin loads to the synaptonemal complex central region independently of meiotic cohesin complexes. EMBO Rep (2016) 0.79
Characterization and in vitro culture of putative spermatogonial stem cells derived from feline testicular tissue. J Reprod Dev (2013) 0.78
Fertility preservation strategies for male patients with cancer. Nat Rev Urol (2013) 0.78
Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes. Cell Rep (2015) 0.78
Development of fertile mouse oocytes from mitotic germ cells in vitro. Nat Protoc (2017) 0.78
Spermatogonial stem cells: Progress and prospects. Asian J Androl (2015) 0.77
Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling. Oncotarget (2016) 0.77
Integrative rodent models for assessing male reproductive toxicity of environmental endocrine active substances. Asian J Androl (2013) 0.77
Plasticity of male germline stem cells and their applications in reproductive and regenerative medicine. Asian J Androl (2015) 0.77
In vitro differentiation of rat spermatogonia into round spermatids in tissue culture. Mol Hum Reprod (2016) 0.77
Generation of a dual-color reporter mouse line to monitor spermatogenesis in vivo. Front Cell Dev Biol (2014) 0.77
Acute slices of mice testis seminiferous tubules unveil spontaneous and synchronous Ca2+ oscillations in germ cell clusters. Biol Reprod (2012) 0.77
Slow freezing, but not vitrification supports complete spermatogenesis in cryopreserved, neonatal sheep testicular xenografts. PLoS One (2015) 0.77
Vitrified canine testicular cells allow the formation of spermatogonial stem cells and seminiferous tubules following their xenotransplantation into nude mice. Sci Rep (2016) 0.76
Cryopreservation of testis tissues and in vitro spermatogenesis. Reprod Med Biol (2015) 0.76
Expression and Localization of Opioid Receptors in Male Germ Cells and the Implication for Mouse Spermatogenesis. PLoS One (2016) 0.76
Cryopreservation of testicular tissue or testicular cell suspensions: a pivotal step in fertility preservation. Hum Reprod Update (2016) 0.76
Making male gametes in culture. Proc Natl Acad Sci U S A (2012) 0.76
Reproductive biology: In vitro sperm maturation. Nature (2011) 0.76
Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS One (2014) 0.76
Is toxicant-induced Sertoli cell injury in vitro a useful model to study molecular mechanisms in spermatogenesis? Semin Cell Dev Biol (2016) 0.75
Words of wisdom: Re: In vitro production of functional sperm in cultured neonatal mouse testes. Eur Urol (2011) 0.75
Processing and selection of surgically-retrieved sperm for ICSI: a review. Basic Clin Androl (2017) 0.75
Multiplex shRNA Screening of Germ Cell Development by In Vivo Transfection of Mouse Testis. G3 (Bethesda) (2016) 0.75
Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties. Stem Cell Reports (2016) 0.75
Spermatogonial Stem Cells Protein Identification in In Vitro Culture from Non-Obstructive Azoospermia Patient. Malays J Med Sci (2016) 0.75
Reconstituting mammalian spermatogenesis using stem cells. Asian J Androl (2011) 0.75
In vitro production of functional sperm in mice. Asian J Androl (2011) 0.75
Irinotecan metabolite SN38 results in germ cell loss in the testis but not in the ovary of prepubertal mice. Mol Hum Reprod (2016) 0.75
Application of three-dimensional culture systems to study mammalian spermatogenesis, with an emphasis on the rhesus monkey (Macaca mulatta). Asian J Androl (2015) 0.75
In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues. PLoS One (2015) 0.75
A future, on ice. Nat Med (2013) 0.75
Male fertility: Is spermiogenesis the critical step for answering biomedical issues? Spermatogenesis (2013) 0.75
Development of reproductive engineering techniques at the RIKEN BioResource Center. Exp Anim (2016) 0.75
Transgender youth: current concepts. Ann Pediatr Endocrinol Metab (2016) 0.75
Effects of the Transforming Growth Factor Beta Signaling Pathway on the Differentiation of Chicken Embryonic Stem Cells into Male Germ Cells. Cell Reprogram (2016) 0.75
Enhancement in colonization of bovine spermatogonial stem cells following addition of knock-out serum replacement to culture medium. Vet Res Forum (2016) 0.75
Use of in ovo chorioallantoic membrane engraftment to culture testes from neonatal mice. Comp Med (2014) 0.75
Male factor infertility: Sperm extraction and culture techniques bring new hope for men once considered infertile. Nat Rev Urol (2011) 0.75
Another piece of the meiosis puzzle. Asian J Androl (2016) 0.75
Can we grow sperm? A translational perspective on the current animal and human spermatogenesis models. Asian J Androl (2011) 0.75
Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device. Sci Rep (2016) 0.75
An integrative omics strategy to assess the germ cell secretome and to decipher sertoli-germ cell crosstalk in the Mammalian testis. PLoS One (2014) 0.75
Generation of fertile sperm in a culture dish: clinical implications. Asian J Androl (2011) 0.75
In vitro generation of Sertoli-like and haploid spermatid-like cells from human umbilical cord perivascular cells. Stem Cell Res Ther (2017) 0.75
Discovering in vitro spermatogenesis stimulating factors. Cell Death Dis (2015) 0.75
A noncoding RNA containing a SINE-B1 motif associates with meiotic metaphase chromatin and has an indispensable function during spermatogenesis. PLoS One (2017) 0.75
Progress and future prospect of in vitro spermatogenesis. Oncotarget (2017) 0.75
Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System. Birth Defects Res (2017) 0.75
Using Ex Vivo Upright Droplet Cultures of Whole Fetal Organs to Study Developmental Processes during Mouse Organogenesis. J Vis Exp (2015) 0.75
Long-term proliferation in culture and germline transmission of mouse male germline stem cells. Biol Reprod (2003) 5.32
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Generation of pluripotent stem cells from neonatal mouse testis. Cell (2004) 3.95
Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue. Biotechniques (2009) 3.04
Promotion of bladder cancer development and progression by androgen receptor signals. J Natl Cancer Inst (2007) 2.59
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development (2002) 2.55
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature (2012) 2.38
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science (2010) 2.34
Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol (2003) 2.24
Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet (2006) 2.19
Ureteroscopy assisted retrograde nephrostomy: a new technique for percutaneous nephrolithotomy (PCNL). BJU Int (2011) 2.14
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta. Nat Genet (2008) 2.13
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nat Genet (2005) 2.13
Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions. Biol Reprod (2004) 2.01
Serum- and feeder-free culture of mouse germline stem cells. Biol Reprod (2010) 1.81
Akt mediates self-renewal division of mouse spermatogonial stem cells. Development (2007) 1.79
VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma. J Natl Cancer Inst (2002) 1.75
Usefulness of the 2005 International Society of Urologic Pathology Gleason grading system in prostate biopsy and radical prostatectomy specimens. BJU Int (2008) 1.68
Genetic and epigenetic properties of mouse male germline stem cells during long-term culture. Development (2005) 1.65
Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc Natl Acad Sci U S A (2012) 1.63
Generation of functional oocytes and spermatids from fetal primordial germ cells after ectopic transplantation in adult mice. Biol Reprod (2010) 1.63
Expression of aquaporin 1 in primary renal tumors: a prognostic indicator for clear-cell renal cell carcinoma. Eur Urol (2008) 1.62
Pluripotency of a single spermatogonial stem cell in mice. Biol Reprod (2008) 1.59
Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma. J Pathol (2005) 1.57
Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor. Oncogene (2003) 1.50
Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr Biol (2005) 1.49
In vitro production of fertile sperm from murine spermatogonial stem cell lines. Nat Commun (2011) 1.49
Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells. Proc Natl Acad Sci U S A (2006) 1.45
Faithful expression of imprinted genes in cloned mice. Science (2002) 1.45
The potential of FDG-PET/CT for detecting prostate cancer in patients with an elevated serum PSA level. Ann Nucl Med (2010) 1.44
Reconstitution of mouse spermatogonial stem cell niches in culture. Cell Stem Cell (2012) 1.41
Receptor for advanced glycation end products (RAGE) and its ligand, amphoterin are overexpressed and associated with prostate cancer development. Prostate (2005) 1.41
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet (2004) 1.40
Evaluation and validation of the core lower urinary tract symptom score as an outcome assessment tool for the treatment of benign prostatic hyperplasia: effects of the α1-adrenoreceptor antagonist silodosin. Int J Urol (2013) 1.39
Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem (2010) 1.37
Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancer. Clin Cancer Res (2005) 1.35
Restoration of spermatogenesis by lentiviral gene transfer: offspring from infertile mice. Proc Natl Acad Sci U S A (2002) 1.35
RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. Proc Natl Acad Sci U S A (2011) 1.34
Recent advancements in cloning by somatic cell nuclear transfer. Philos Trans R Soc Lond B Biol Sci (2013) 1.33
Angiotensin II receptor blocker shows antiproliferative activity in prostate cancer cells: a possibility of tyrosine kinase inhibitor of growth factor. Mol Cancer Ther (2003) 1.31
Sperm cryopreservation before cancer chemotherapy helps in the emotional battle against cancer. Cancer (2005) 1.28
Regulation of spermatogenesis by testis-specific, cytoplasmic poly(A) polymerase TPAP. Science (2002) 1.27
BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin. In Vitro Cell Dev Biol Anim (2009) 1.25
Early ureteral catheter removal after ureteroscopic lithotripsy using ureteral access sheath. Urolithiasis (2012) 1.25
Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinoma. Clin Cancer Res (2007) 1.19
Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells. Proc Natl Acad Sci U S A (2007) 1.19
Clonal origin of germ cell colonies after spermatogonial transplantation in mice. Biol Reprod (2006) 1.17
In vitro murine spermatogenesis in an organ culture system. Biol Reprod (2010) 1.17