Published in J Immunol on April 15, 2002
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Organization of proximal signal initiation at the TCR:CD3 complex. Immunol Rev (2009) 1.25
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Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. J Exp Med (2006) 1.13
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Modulation of Kv channel expression and function by TCR and costimulatory signals during peripheral CD4(+) lymphocyte differentiation. J Exp Med (2002) 1.07
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Sustained interactions between T cell receptors and antigens promote the differentiation of CD4⁺ memory T cells. Immunity (2013) 1.03
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Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol (2008) 0.94
Dendritic epidermal T cells regulate skin antimicrobial barrier function. J Clin Invest (2013) 0.94
Altered T-cell receptor signaling in the pathogenesis of allergic disease. J Allergy Clin Immunol (2011) 0.92
Immunological synapse: a multi-protein signalling cellular apparatus for controlling gene expression. Immunology (2010) 0.91
Transcriptional regulatory networks for CD4 T cell differentiation. Curr Top Microbiol Immunol (2014) 0.86
NIP45 controls the magnitude of the type 2 T helper cell response. Proc Natl Acad Sci U S A (2010) 0.85
Grail controls Th2 cell development by targeting STAT6 for degradation. Nat Commun (2014) 0.84
Mice lacking the IFN-gamma receptor or fyn develop severe experimental autoimmune uveoretinitis characterized by different immune responses. Immunogenetics (2005) 0.84
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling. BMC Immunol (2012) 0.84
Disorderly conduct in gammadelta versus alphabeta T cell lineage commitment. Semin Immunol (2010) 0.82
Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response. Front Immunol (2015) 0.80
Regulatory role of pro-Th1 and pro-Th2 cytokines in modulating the activity of Th1 and Th2 cells when B cell and macrophages are used as antigen presenting cells. BMC Immunol (2006) 0.80
Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis. Immunology (2014) 0.79
Leukocyte pyruvate kinase expression is reduced in normal human pregnancy but not in pre-eclampsia. Am J Reprod Immunol (2010) 0.79
Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation. J Immunol (2012) 0.78
Dynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus. PLoS Pathog (2014) 0.78
TCR Signal Strength Alters T-DC Activation and Interaction Times and Directs the Outcome of Differentiation. Front Immunol (2016) 0.77
TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma. J Clin Cell Immunol (2012) 0.77
Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile. BMC Biol (2014) 0.77
Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other. PLoS One (2014) 0.77
Molecular basis for T cell response induced by altered peptide ligand of type II collagen. J Biol Chem (2012) 0.76
Fyn regulates eosinophil infiltration into the conjunctiva by downregulating the Th2 response. Graefes Arch Clin Exp Ophthalmol (2005) 0.76
Limited T-cell receptor diversity predisposes to Th2 immunopathology: involvement of Tregs and conventional CD4 T cells. J Clin Immunol (2008) 0.75
Immunotherapeutic potential of the immunodominant T-cell epitope of lipocalin allergen Bos d 2 and its analogues. Immunology (2007) 0.75
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med (2002) 6.48
To respond or not to respond: T cells in allergic asthma. Nat Rev Immunol (2003) 3.14
MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest (2005) 2.20
Dual receptor T cells extend the immune repertoire for foreign antigens. Nat Immunol (2002) 1.96
Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. J Clin Invest (2002) 1.66
An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc Natl Acad Sci U S A (2003) 1.65
Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. J Immunol (2006) 1.56
Cytolytic CD4(+)-T-cell clones reactive to EBNA1 inhibit Epstein-Barr virus-induced B-cell proliferation. J Virol (2003) 1.36
Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells. J Immunol (2003) 1.35
The master regulators of allergic inflammation: dendritic cells in Th2 sensitization. Curr Opin Immunol (2003) 1.19
IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen. J Immunol (2003) 1.16
A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge. J Allergy Clin Immunol (2002) 1.11
Engineered recombinant peanut protein and heat-killed Listeria monocytogenes coadministration protects against peanut-induced anaphylaxis in a murine model. J Immunol (2003) 1.07
A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol (2004) 1.05
Understanding asthma pathogenesis: linking innate and adaptive immunity. Curr Opin Pediatr (2004) 1.01
IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88. J Immunol (2004) 1.00
CD4 raft association and signaling regulate molecular clustering at the immunological synapse site. J Immunol (2004) 0.94
A pool of central memory-like CD4 T cells contains effector memory precursors. J Immunol (2003) 0.94
Innate immune control of pulmonary dendritic cell trafficking. Proc Am Thorac Soc (2007) 0.93
CTLA-4 differentially regulates the immunological synapse in CD4 T cell subsets. J Immunol (2007) 0.92
Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. J Allergy Clin Immunol (2003) 0.90
Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation. Clin Immunol (2009) 0.89
Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. J Immunol (2004) 0.88
Targeting Toll-like receptors on dendritic cells modifies the T(H)2 response to peanut allergens in vitro. J Allergy Clin Immunol (2010) 0.87
Inhibition of TLR activation and up-regulation of IL-1R-associated kinase-M expression by exogenous gangliosides. J Immunol (2008) 0.87
Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells. Cell Motil Cytoskeleton (2007) 0.86
p21 Ras/impedes mitogenic signal propagation regulates cytokine production and migration in CD4 T cells. J Biol Chem (2008) 0.86
Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development. J Immunol (2007) 0.86
Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction. Gene (2013) 0.84
P27kip1 regulates the cell cycle arrest and survival of activated T lymphocytes in response to interleukin-2 withdrawal. Immunology (2003) 0.82
Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro. J Immunol (2005) 0.81
Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development. J Immunol (2008) 0.80
Activation of CD4 T cells by Raf-independent effectors of Ras. Proc Natl Acad Sci U S A (2003) 0.80
The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. J Immunol (2002) 0.80
Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate. J Allergy Clin Immunol (2003) 0.80
Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes. J Immunol (2012) 0.79
EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation. Immunology (2011) 0.78
Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity. Immunology (2010) 0.77
CD4 co-receptor dependent signaling promotes competency for re-stimulation induced cell death of effector T cells. Cell Immunol (2010) 0.75
CD4-dependent signaling is required for a late checkpoint during Th2 development associated with resistance to activation-induced cell death. J Immunol (2005) 0.75
Isolated del(14)(q21) in a case of precursor B-cell acute lymphoblastic leukemia. Cancer Genet Cytogenet (2005) 0.75