Published in J Pharm Sci on April 01, 2002
Injectable lipid emulsions-advancements, opportunities and challenges. AAPS PharmSciTech (2010) 0.93
Application of poly(ethylene glycol)-distearoylphosphatidylethanolamine (PEG-DSPE) block copolymers and their derivatives as nanomaterials in drug delivery. Int J Nanomedicine (2012) 0.86
Preclinical formulations: insight, strategies, and practical considerations. AAPS PharmSciTech (2014) 0.77
RGD-modified liposomes enhance efficiency of aclacinomycin A delivery: evaluation of their effect in lung cancer. Drug Des Devel Ther (2015) 0.75
Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Deliv Rev (2007) 1.85
Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon. J Control Release (2012) 1.46
Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography. J Control Release (2010) 1.41
Evaluation of the disintegration time of rapidly disintegrating tablets via a novel method utilizing a CCD camera. Chem Pharm Bull (Tokyo) (2002) 1.25
Once-daily propranolol extended-release tablet dosage form: formulation design and in vitro/in vivo investigation. Eur J Pharm Biopharm (2004) 1.13
Mucosal insulin delivery systems based on complexation polymer hydrogels: effect of particle size on insulin enteral absorption. J Control Release (2004) 1.12
Novel oral insulin delivery systems based on complexation polymer hydrogels: single and multiple administration studies in type 1 and 2 diabetic rats. J Control Release (2005) 1.10
Elucidation of the mechanism of incorporation of insulin in controlled release systems based on complexation polymers. J Control Release (2002) 1.06
Design of folate-linked liposomal doxorubicin to its antitumor effect in mice. Clin Cancer Res (2008) 1.04
Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res (2005) 1.03
Characterization of insulin protection properties of complexation hydrogels in gastric and intestinal enzyme fluids. J Control Release (2006) 1.02
Region-dependent role of the mucous/glycocalyx layers in insulin permeation across rat small intestinal membrane. Pharm Res (2005) 1.01
Complexation hydrogels for intestinal delivery of interferon beta and calcitonin. J Control Release (2008) 1.01
Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate. Int J Pharm (2006) 1.00
Persistent and stable gene expression by a cytoplasmic RNA replicon based on a noncytopathic variant Sendai virus. J Biol Chem (2007) 0.99
Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion. J Control Release (2008) 0.98
Usefulness of cell-penetrating peptides to improve intestinal insulin absorption. J Control Release (2008) 0.97
Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther (2005) 0.97
Gastrointestinal transit and mucoadhesive characteristics of complexation hydrogels in rats. J Pharm Sci (2006) 0.96
Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers. Int J Pharm (2010) 0.95
Enhanced antitumor effect of camptothecin loaded in long-circulating polymeric micelles. J Control Release (2006) 0.95
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting. Pharm Res (2004) 0.94
Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: effect of chain length and amount of folate-PEG linker. J Drug Target (2008) 0.94
In vivo antitumor activity of camptothecin incorporated in liposomes formulated with an artificial lipid and human serum albumin. J Control Release (2008) 0.94
Improvement in the bioavailability of poorly absorbed glycyrrhizin via various non-vascular administration routes in rats. Int J Pharm (2003) 0.93
Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability. Int J Pharm (2006) 0.93
Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts. Eur J Pharm Biopharm (2008) 0.92
Folate-linked lipid-based nanoparticle for targeted gene delivery. Curr Drug Deliv (2005) 0.92
Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect. J Control Release (2006) 0.92
Novel chitosan particles and chitosan-coated emulsions inducing immune response via intranasal vaccine delivery. Pharm Res (2004) 0.92
Superparamagnetic iron oxide nanoparticles stabilized by alginate: pharmacokinetics, tissue distribution, and applications in detecting liver cancers. Int J Pharm (2007) 0.92
Influence of serum and albumins from different species on stability of camptothecin-loaded micelles. J Control Release (2005) 0.92
Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres. J Control Release (2006) 0.92
Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients. Drug Metab Dispos (2007) 0.91
PEG-PLA diblock copolymer micelle-like nanoparticles as all-trans-retinoic acid carrier: in vitro and in vivo characterizations. Nanotechnology (2009) 0.90
Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents. J Control Release (2009) 0.89
Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection. J Gene Med (2007) 0.89
The effects of water-soluble cyclodextrins on the histological integrity of the rat nasal mucosa. Int J Pharm (2002) 0.89
In situ ileal absorption of insulin in rats: effects of hyaluronidase pretreatment diminishing the mucous/glycocalyx layers. Pharm Res (2004) 0.89
Highly efficient cationic hydroxyethylated cholesterol-based nanoparticle-mediated gene transfer in vivo and in vitro in prostate carcinoma PC-3 cells. J Control Release (2007) 0.89
Polymeric micelles modified by folate-PEG-lipid for targeted drug delivery to cancer cells in vitro. J Nanosci Nanotechnol (2008) 0.88
Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors. J Control Release (2009) 0.88
siRNA delivery into tumor cells by lipid-based nanoparticles composed of hydroxyethylated cholesteryl triamine. Int J Pharm (2012) 0.88
Multivariate statistical approach to optimizing sustained-release tablet formulations containing diltiazem hydrochloride as a model highly water-soluble drug. Int J Pharm (2009) 0.88
The proximal STAT6 and NF-kappaB sites are responsible for IL-13- and TNF-alpha-induced RhoA transcriptions in human bronchial smooth muscle cells. Pharmacol Res (2009) 0.87
Accelerated blood clearance was not induced for a gadolinium-containing PEG-poly(L-lysine)-based polymeric micelle in mice. Pharm Res (2009) 0.87
An accurate quantitative analysis of polymorphs based on artificial neural networks. Colloids Surf B Biointerfaces (2006) 0.87
Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides. J Control Release (2009) 0.87
What are determining factors for stable drug incorporation into polymeric micelle carriers? Consideration on physical and chemical characters of the micelle inner core. J Control Release (2007) 0.87
Magnetic targeting after femoral artery administration and biocompatibility assessment of superparamagnetic iron oxide nanoparticles. J Biomed Mater Res A (2008) 0.86
A novel approach using functional peptides for efficient intestinal absorption of insulin. J Control Release (2006) 0.86
Anionic polymer-coated lipoplex for safe gene delivery into tumor by systemic injection. J Drug Target (2013) 0.86
Molecular characterization of tumors from a transgenic mouse adrenal tumor model: comparison with human pheochromocytoma. Int J Oncol (2010) 0.86
Non-viral delivery of the connexin 43 gene with histone deacetylase inhibitor to human nasopharyngeal tumor cells enhances gene expression and inhibits in vivo tumor growth. Int J Oncol (2007) 0.86
Organic nanotubes for drug loading and cellular delivery. Int J Pharm (2011) 0.86
Ultra-deformable liposomes containing bleomycin: in vitro stability and toxicity on human cutaneous keratinocyte cell lines. Int J Pharm (2005) 0.86
Formulation optimization of water-in-oil-water multiple emulsion for intestinal insulin delivery. J Control Release (2004) 0.86
Involvement of transcription factor Ets-1 in the expression of the α3 integrin subunit gene. FEBS J (2012) 0.86
Enhanced antitumor efficacy of folate-linked liposomal doxorubicin with TGF-β type I receptor inhibitor. Cancer Sci (2010) 0.85
Sustained release of cisplatin from multivesicular liposomes: potentiation of antitumor efficacy against S180 murine carcinoma. J Pharm Sci (2004) 0.85
The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides. Int J Pharm (2010) 0.85
Development of high boron content liposomes and their promising antitumor effect for neutron capture therapy of cancers. Bioconjug Chem (2012) 0.84
Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma. Cancer Med (2013) 0.84
Effects of polyethylene glycol spacer length and ligand density on folate receptor targeting of liposomal Doxorubicin in vitro. J Drug Deliv (2010) 0.84
Role of the mucous/glycocalyx layers in insulin permeation across the rat ileal membrane. Int J Pharm (2005) 0.84
Collagenase-1 injection improved tumor distribution and gene expression of cationic lipoplex. Int J Pharm (2011) 0.84
Functional coating of liposomes using a folate- polymer conjugate to target folate receptors. Int J Nanomedicine (2012) 0.84
Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs. Int J Pharm (2002) 0.84
Folate-linked lipid-based nanoparticles deliver a NFkappaB decoy into activated murine macrophage-like RAW264.7 cells. Biol Pharm Bull (2006) 0.84
Stability and antitumor effects of all-trans retinoic acid-loaded liposomes contained sterylglucoside mixture. Int J Pharm (2003) 0.83
Polymer design and incorporation methods for polymeric micelle carrier system containing water-insoluble anti-cancer agent camptothecin. J Drug Target (2004) 0.83
Creation of a tablet database containing several active ingredients and prediction of their pharmaceutical characteristics based on ensemble artificial neural networks. J Pharm Sci (2010) 0.83
High gene delivery in tumor by intratumoral injection of tetraarginine-PEG lipid-coated protamine/DNA. J Control Release (2008) 0.83
Higher liposomal membrane fluidity enhances the in vitro antitumor activity of folate-targeted liposomal mitoxantrone. Mol Pharm (2009) 0.83
Effect of excipients on breast cancer resistance protein substrate uptake activity. J Control Release (2007) 0.83
Combination of non-viral connexin 43 gene therapy and docetaxel inhibits the growth of human prostate cancer in mice. Int J Oncol (2007) 0.83
Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer. J Control Release (2004) 0.83
Cell line-dependent internalization pathways determine DNA transfection efficiency of decaarginine-PEG-lipid. Int J Pharm (2010) 0.82
Adrenal tumor volume in a genetically engineered mouse model of neuroblastoma determined by magnetic resonance imaging. Exp Ther Med (2012) 0.82
A statistical approach to the development of a transdermal delivery system for ondansetron. Int J Pharm (2010) 0.82
Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins. Int J Pharm (2009) 0.82
Pharmacokinetics and antitumor effects of vincristine carried by microemulsions composed of PEG-lipid, oleic acid, vitamin E and cholesterol. Int J Pharm (2003) 0.82
p-Dodecylaminophenol derived from the synthetic retinoid, fenretinide: antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of action. Int J Cancer (2008) 0.82
Docosahexaenoic acid and eicosapentaenoic acid induce changes in the physical properties of a lipid bilayer model membrane. Chem Pharm Bull (Tokyo) (2006) 0.82
Evaluation of the reliability of nonlinear optimal solutions in pharmaceuticals using a bootstrap resampling technique in combination with Kohonen's self-organizing maps. J Pharm Sci (2008) 0.81
Long-circulating liposome-encapsulated ganciclovir enhances the efficacy of HSV-TK suicide gene therapy. J Control Release (2007) 0.81
Two-step transcriptional amplification-lipid-based nanoparticles using PSMA or midkine promoter for suicide gene therapy in prostate cancer. Cancer Sci (2006) 0.81
Development of an in vitro drug release assay of PEGylated liposome using bovine serum albumin and high temperature. Biol Pharm Bull (2010) 0.81
Octreotide-targeted liposomes loaded with CPT-11 enhanced cytotoxicity for the treatment of medullary thyroid carcinoma. Mol Pharm (2011) 0.81
Displacement of tight junction proteins from detergent-resistant membrane domains by treatment with sodium caprate. Eur J Pharm Sci (2008) 0.81
In vitro and in vivo evaluation of mucoadhesive microspheres consisting of dextran derivatives and cellulose acetate butyrate. Int J Pharm (2003) 0.81
Formulation optimization of photocrosslinked polyacrylic acid modified with 2-hydroxyethyl methacrylate hydrogel as an adhesive for a dermatological patch. J Control Release (2005) 0.81
Structural requirements of penetratin absorption enhancement efficiency for insulin delivery. J Control Release (2010) 0.81
Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin. J Control Release (2006) 0.81
Development of photocrosslinked polyacrylic acid hydrogel as an adhesive for dermatological patches: involvement of formulation factors in physical properties and pharmacological effects. Int J Pharm (2007) 0.80
Influence of pectins on preparation characteristics of lactoferrin bioadhesive tablets. Chem Pharm Bull (Tokyo) (2007) 0.80
Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis. Cancer Sci (2010) 0.80