Published in Cancer Med on April 02, 2013
(18)F-alfatide II and (18)F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy. J Nucl Med (2013) 0.94
In vivo siRNA delivery system for targeting to the liver by poly-l-glutamic acid-coated lipoplex. Results Pharma Sci (2014) 0.79
Rhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways. Oncotarget (2015) 0.77
Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis. Oncotarget (2015) 0.75
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res (1986) 15.83
Neuroblastoma. Lancet (2007) 10.61
The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol (2005) 4.54
Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev (1999) 4.02
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res (2000) 3.75
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci U S A (2007) 2.30
Advances in the diagnosis and treatment of neuroblastoma. Oncologist (2003) 2.17
50 years of preclinical anticancer drug screening: empirical to target-driven approaches. Clin Cancer Res (2005) 1.86
Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours. Drugs (1997) 1.76
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens. Nature (2003) 1.55
Insertion of poly(ethylene glycol) derivatized phospholipid into pre-formed liposomes results in prolonged in vivo circulation time. FEBS Lett (1996) 1.46
Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer Res (2004) 1.41
Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res (2009) 1.35
Proliferation of human neuroblastomas mediated by the epidermal growth factor receptor. Cancer Res (2005) 1.23
Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients. Biochim Biophys Acta (1990) 1.21
Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines. Arch Otolaryngol Head Neck Surg (2007) 1.15
Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin. Clin Cancer Res (2008) 1.14
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature. Cancer Sci (2008) 1.10
Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells. Biochem Biophys Res Commun (2007) 1.10
Preclinical models for neuroblastoma: establishing a baseline for treatment. PLoS One (2011) 1.09
Identification of low intratumoral gene expression heterogeneity in neuroblastic tumors by genome-wide expression analysis and game theory. Cancer (2008) 1.06
Lestaurtinib enhances the antitumor efficacy of chemotherapy in murine xenograft models of neuroblastoma. Clin Cancer Res (2010) 1.02
Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression. Carcinogenesis (2000) 0.97
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release (2010) 0.96
Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. Int J Cancer (2009) 0.95
The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo. Med Pediatr Oncol (2001) 0.93
Improved tumor vascular function following high-dose epidermal growth factor receptor tyrosine kinase inhibitor therapy. J Magn Reson Imaging (2007) 0.92
A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma. Invest New Drugs (2011) 0.89
Molecular characterization of tumors from a transgenic mouse adrenal tumor model: comparison with human pheochromocytoma. Int J Oncol (2010) 0.86
Increase in tumour permeability following TGF-beta type I receptor-inhibitor treatment observed by dynamic contrast-enhanced MRI. Br J Cancer (2009) 0.85
Enhanced antitumor efficacy of folate-linked liposomal doxorubicin with TGF-β type I receptor inhibitor. Cancer Sci (2010) 0.85
Establishment of a novel neuroblastoma mouse model. Int J Oncol (2008) 0.83
Adrenal tumor volume in a genetically engineered mouse model of neuroblastoma determined by magnetic resonance imaging. Exp Ther Med (2012) 0.82
Prolonged response to oral gefitinib, cyclophosphamide, and topotecan in heavily pretreated relapsed stage 4 neuroblastoma: a case report. J Pediatr Hematol Oncol (2007) 0.80
Evaluation of antitumor activity of gefitinib in pediatric glioblastoma and neuroblastoma cells. Clin Lab (2011) 0.78
Antitumor activity of doxorubicin encapsulated in poly(ethylene glycol)-coated liposomes. Biol Pharm Bull (1995) 0.77
Thyroid hormone action is disrupted by bisphenol A as an antagonist. J Clin Endocrinol Metab (2002) 2.49
A link between FTO, ghrelin, and impaired brain food-cue responsivity. J Clin Invest (2013) 2.23
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J (2002) 1.73
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress. J Hypertens (2005) 1.61
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J Clin Endocrinol Metab (2007) 1.57
Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease. J Clin Endocrinol Metab (2005) 1.48
Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon. J Control Release (2012) 1.46
Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice. Arterioscler Thromb Vasc Biol (2008) 1.34
SNPs in the promoter of a B cell-specific antisense transcript, SAS-ZFAT, determine susceptibility to autoimmune thyroid disease. Hum Mol Genet (2004) 1.32
Genomic structure and characterization of the 5'-flanking region of the human ghrelin gene. Endocrinology (2004) 1.30
Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas. Cell Metab (2006) 1.28
Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology (2002) 1.19
Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: vasorelaxation in response to globular adiponectin. Biochem Biophys Res Commun (2005) 1.14
Effect of nanoscale curvature of single-walled carbon nanotubes on adsorption of polycyclic aromatic hydrocarbons. Nano Lett (2007) 1.14
Transgenic mice overexpressing des-acyl ghrelin show small phenotype. Endocrinology (2004) 1.13
Ghrelin for cachexia. J Cachexia Sarcopenia Muscle (2010) 1.12
PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation. Life Sci (2008) 1.09
C-C chemokine receptor 2 inhibitor improves diet-induced development of insulin resistance and hepatic steatosis in mice. J Atheroscler Thromb (2010) 1.09
Porous lanthanide-organic frameworks: synthesis, characterization, and unprecedented gas adsorption properties. J Am Chem Soc (2003) 1.07
Pioglitazone treatment of insulin resistance in a patient with Werner's syndrome. Diabetes Care (2004) 1.05
Comment on "thyrotropin receptor expression in cardiac muscle tissue". J Clin Endocrinol Metab (2002) 1.05
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am J Nephrol (2003) 1.05
Design of folate-linked liposomal doxorubicin to its antitumor effect in mice. Clin Cancer Res (2008) 1.04
Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res (2005) 1.03
Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis. J Biol Chem (2007) 1.03
Alterations of plasma ghrelin levels in rats with lipopolysaccharide-induced wasting syndrome and effects of ghrelin treatment on the syndrome. Endocrinology (2003) 1.03
Buthionine sulfoximine causes endothelium dependent hyper-relaxation and hypoadiponectinemia. Life Sci (2006) 1.02
Cationic liposome (DC-Chol/DOPE=1:2) and a modified ethanol injection method to prepare liposomes, increased gene expression. Int J Pharm (2007) 1.02
Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem (2010) 1.01
Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Mol Ther (2003) 1.01
Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. Endocrinology (2010) 1.01
Acylated ghrelin level in patients with OSA before and after nasal CPAP treatment. Respirology (2008) 1.00
Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate. Int J Pharm (2006) 1.00
Association of the T-cell regulatory gene CTLA4 with Graves' disease and autoimmune thyroid disease in the Japanese. J Hum Genet (2004) 1.00
Efficient microwave-assisted prenylation of pinostrobin and biological evaluation of its derivatives as antitumor agents. Bioorg Med Chem Lett (2010) 0.99
Adiponectin induces NF-kappaB activation that leads to suppression of cytokine-induced NF-kappaB activation in vascular endothelial cells: globular adiponectin vs. high molecular weight adiponectin. Diab Vasc Dis Res (2008) 0.99
Retracted Hypoadiponectinemia is caused by chronic blockade of nitric oxide synthesis in rats. Metabolism (2005) 0.99
Establishment of a novel ghrelin-producing cell line. Endocrinology (2010) 0.99
Aldosterone impairs vascular endothelial cell function. J Cardiovasc Pharmacol (2006) 0.98
Suppression of experimental autoimmune encephalomyelitis by ghrelin. J Immunol (2009) 0.97
Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther (2005) 0.97
Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat. Med Sci Monit (2002) 0.96
Enhanced antitumor effect of camptothecin loaded in long-circulating polymeric micelles. J Control Release (2006) 0.95
Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. Regul Pept (2009) 0.94
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting. Pharm Res (2004) 0.94
Cilostazol activates AMP-activated protein kinase and restores endothelial function in diabetes. Am J Hypertens (2008) 0.94
Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line, MGN3-1 in vitro. Endocrinology (2011) 0.94
Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: effect of chain length and amount of folate-PEG linker. J Drug Target (2008) 0.94
In vivo antitumor activity of camptothecin incorporated in liposomes formulated with an artificial lipid and human serum albumin. J Control Release (2008) 0.94
Ghrelin increases hunger and food intake in patients with restricting-type anorexia nervosa: a pilot study. Endocr J (2009) 0.94
Mulberry leaf ameliorates the expression profile of adipocytokines by inhibiting oxidative stress in white adipose tissue in db/db mice. Atherosclerosis (2008) 0.93
Globular adiponectin induces adhesion molecule expression through the sphingosine kinase pathway in vascular endothelial cells. Life Sci (2007) 0.93
Plasma levels of active form of ghrelin during oral glucose tolerance test in patients with anorexia nervosa. Eur J Endocrinol (2003) 0.93
Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability. Int J Pharm (2006) 0.93
Ventricular fibrillation due to severe hypokalemia induced by steroid treatment in a patient with thyrotoxic periodic paralysis. Intern Med (2006) 0.93
Folate-linked lipid-based nanoparticle for targeted gene delivery. Curr Drug Deliv (2005) 0.92
Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts. Eur J Pharm Biopharm (2008) 0.92
Elevated serum immunoglobulin G4 levels in patients with Graves' disease and their clinical implications. Thyroid (2014) 0.92
Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect. J Control Release (2006) 0.92
Novel chitosan particles and chitosan-coated emulsions inducing immune response via intranasal vaccine delivery. Pharm Res (2004) 0.92
Superparamagnetic iron oxide nanoparticles stabilized by alginate: pharmacokinetics, tissue distribution, and applications in detecting liver cancers. Int J Pharm (2007) 0.92
Influence of serum and albumins from different species on stability of camptothecin-loaded micelles. J Control Release (2005) 0.92
Plasma acylated ghrelin levels correlate with subjective symptoms of functional dyspepsia in female patients. Scand J Gastroenterol (2005) 0.92
Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres. J Control Release (2006) 0.92
Glucose upregulates plasminogen activator inhibitor-1 gene expression in vascular smooth muscle cells. Life Sci (2002) 0.92
GPR40 gene expression in human pancreas and insulinoma. Biochem Biophys Res Commun (2005) 0.91
The -590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease. Clin Chem (2008) 0.91
Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation. Metabolism (2010) 0.91
Telmisartan inhibits cytokine-induced nuclear factor-kappaB activation independently of the peroxisome proliferator-activated receptor-gamma. Hypertens Res (2009) 0.91
Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. PLoS One (2012) 0.91
Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients. Cardiovasc Diabetol (2011) 0.91
PEG-PLA diblock copolymer micelle-like nanoparticles as all-trans-retinoic acid carrier: in vitro and in vivo characterizations. Nanotechnology (2009) 0.90
Microbial diversity with dominance of 16S rRNA gene sequences with high GC contents at 74 and 98 °C subsurface crude oil deposits in Japan. FEMS Microbiol Ecol (2011) 0.90
Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice. J Biol Chem (2005) 0.90
Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents. J Control Release (2009) 0.89
Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection. J Gene Med (2007) 0.89
Highly efficient cationic hydroxyethylated cholesterol-based nanoparticle-mediated gene transfer in vivo and in vitro in prostate carcinoma PC-3 cells. J Control Release (2007) 0.89
Ghrelin and functional dyspepsia. Int J Pept (2010) 0.88
siRNA delivery into tumor cells by lipid-based nanoparticles composed of hydroxyethylated cholesteryl triamine. Int J Pharm (2012) 0.88
Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development. Dev Dyn (2007) 0.88
Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors. J Control Release (2009) 0.88
Polymeric micelles modified by folate-PEG-lipid for targeted drug delivery to cancer cells in vitro. J Nanosci Nanotechnol (2008) 0.88
A mouse model of ghrelinoma exhibited activated growth hormone-insulin-like growth factor I axis and glucose intolerance. Am J Physiol Endocrinol Metab (2009) 0.88
Tetrahydrobiopterin prevents endothelial dysfunction and restores adiponectin levels in rats. Eur J Pharmacol (2006) 0.87
The proximal STAT6 and NF-kappaB sites are responsible for IL-13- and TNF-alpha-induced RhoA transcriptions in human bronchial smooth muscle cells. Pharmacol Res (2009) 0.87
Accelerated blood clearance was not induced for a gadolinium-containing PEG-poly(L-lysine)-based polymeric micelle in mice. Pharm Res (2009) 0.87
Phenanthrene adsorption from solution on single wall carbon nanotubes. J Phys Chem B (2006) 0.87