Published in Nucleic Acids Res on May 01, 2002
Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data. Nucleic Acids Res (2009) 9.64
Statistical analysis of real-time PCR data. BMC Bioinformatics (2006) 7.31
Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet (2009) 4.49
Standardized determination of real-time PCR efficiency from a single reaction set-up. Nucleic Acids Res (2003) 4.46
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev (2004) 4.41
Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature (2009) 4.13
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. J Clin Invest (2006) 3.95
A standard curve based method for relative real time PCR data processing. BMC Bioinformatics (2005) 3.85
Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. J Immunol (2008) 3.07
HDAC3 is a critical negative regulator of long-term memory formation. J Neurosci (2011) 3.06
The molecular basis of temperature compensation in the Arabidopsis circadian clock. Plant Cell (2006) 2.84
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. EMBO J (2009) 2.83
Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med (2009) 2.73
Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc Natl Acad Sci U S A (2007) 2.72
Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet (2014) 2.70
Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes. Environ Health Perspect (2008) 2.56
The miR-144/451 locus is required for erythroid homeostasis. J Exp Med (2010) 2.54
Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol (2008) 2.51
Characterization of transcriptional complexity during berry development in Vitis vinifera using RNA-Seq. Plant Physiol (2010) 2.46
Retracted FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer. J Clin Invest (2011) 2.44
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nat Biotechnol (2011) 2.43
Lymphotoxin-mediated crosstalk between B cells and splenic stroma promotes the initial type I interferon response to cytomegalovirus. Cell Host Microbe (2008) 2.40
Towards a systematic validation of references in real-time rt-PCR. Plant Cell (2008) 2.37
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neurosci (2010) 2.34
Relative quantification of mRNA: comparison of methods currently used for real-time PCR data analysis. BMC Mol Biol (2007) 2.31
Clinical strains of Pseudomonas aeruginosa overproducing MexAB-OprM and MexXY efflux pumps simultaneously. Antimicrob Agents Chemother (2004) 2.26
Engineering synthetic TAL effectors with orthogonal target sites. Nucleic Acids Res (2012) 2.25
Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genet (2005) 2.19
Wolbachia infections are virulent and inhibit the human malaria parasite Plasmodium falciparum in Anopheles gambiae. PLoS Pathog (2011) 2.18
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J Exp Med (2008) 2.15
Differential gene expression of TRPM1, the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa horse (Equus caballus). Genetics (2008) 2.15
Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis. Genome Biol (2009) 2.04
Epigenetic effects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual conflict. Proc Natl Acad Sci U S A (2010) 2.01
The low-oxygen-induced NAC domain transcription factor ANAC102 affects viability of Arabidopsis seeds following low-oxygen treatment. Plant Physiol (2009) 1.94
Twin RNA polymerase-associated proteins control virulence gene expression in Francisella tularensis. PLoS Pathog (2007) 1.92
Microbial excavation of solid carbonates powered by P-type ATPase-mediated transcellular Ca2+ transport. Proc Natl Acad Sci U S A (2010) 1.89
Broad epigenetic signature of maternal care in the brain of adult rats. PLoS One (2011) 1.86
Validation of reference genes for quantitative real-time PCR during leaf and flower development in Petunia hybrida. BMC Plant Biol (2010) 1.82
Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials (2008) 1.82
Wolbachia-mediated resistance to dengue virus infection and death at the cellular level. PLoS One (2010) 1.81
DNA as an adhesin: Bacillus cereus requires extracellular DNA to form biofilms. Appl Environ Microbiol (2009) 1.77
Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet (2007) 1.77
Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium. J Clin Invest (2009) 1.75
Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory. Neuropsychopharmacology (2011) 1.74
Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity. Neuron (2011) 1.73
Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway. Neuroscience (2009) 1.73
An Arabidopsis GPI-anchor plasmodesmal neck protein with callose binding activity and potential to regulate cell-to-cell trafficking. Plant Cell (2009) 1.65
Claudin-1, -3 and -4 proteins and mRNA expression in benign and malignant breast lesions: a research study. Breast Cancer Res (2005) 1.65
An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. PLoS One (2009) 1.63
The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora. Mol Microbiol (2007) 1.63
Global identification of targets of the Arabidopsis MADS domain protein AGAMOUS-Like15. Plant Cell (2009) 1.63
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure. Genome Res (2010) 1.62
Multiple controls affect arsenite oxidase gene expression in Herminiimonas arsenicoxydans. BMC Microbiol (2010) 1.59
Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? J Neurosci (2009) 1.57
Induction of the MexXY efflux pump in Pseudomonas aeruginosa is dependent on drug-ribosome interaction. J Bacteriol (2005) 1.55
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Gastroenterology (2006) 1.54
2,3-butanediol production by acetogenic bacteria, an alternative route to chemical synthesis, using industrial waste gas. Appl Environ Microbiol (2011) 1.54
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma. Cancer Metab (2013) 1.53
Central role of c-Myc during malignant conversion in human hepatocarcinogenesis. Cancer Res (2009) 1.50
Evaluation of reference genes for real-time RT-PCR expression studies in the plant pathogen Pectobacterium atrosepticum. BMC Plant Biol (2007) 1.48
Neutrophil gelatinase-associated lipocalin mediates 13-cis retinoic acid-induced apoptosis of human sebaceous gland cells. J Clin Invest (2008) 1.47
Faster quantitative real-time PCR protocols may lose sensitivity and show increased variability. Nucleic Acids Res (2005) 1.47
Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J Clin Invest (2011) 1.46
Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Mol Cell (2012) 1.46
The VHL-dependent regulation of microRNAs in renal cancer. BMC Med (2010) 1.46
Aging decreases L-type calcium channel currents and pacemaker firing fidelity in substantia nigra dopamine neurons. J Neurosci (2014) 1.46
Theobroma cacao L. pathogenesis-related gene tandem array members show diverse expression dynamics in response to pathogen colonization. BMC Genomics (2016) 1.43
Relative transcript quantification by quantitative PCR: roughly right or precisely wrong? BMC Mol Biol (2005) 1.42
Specific and sensitive quantitative RT-PCR of miRNAs with DNA primers. BMC Biotechnol (2011) 1.42
Correlation of SATB1 overexpression with the progression of human rectal cancer. Int J Colorectal Dis (2011) 1.40
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. Nature (2017) 1.40
Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β. J Leukoc Biol (2012) 1.40
A novel antifungal is active against Candida albicans biofilms and inhibits mutagenic acetaldehyde production in vitro. PLoS One (2014) 1.40
Improved quantitative real-time RT-PCR for expression profiling of individual cells. Nucleic Acids Res (2002) 1.40
Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model. BMC Mol Biol (2008) 1.39
L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One (2014) 1.39
Autoinducer-2-regulated genes in Streptococcus mutans UA159 and global metabolic effect of the luxS mutation. J Bacteriol (2007) 1.37
Upgrading root physiology for stress tolerance by ectomycorrhizas: insights from metabolite and transcriptional profiling into reprogramming for stress anticipation. Plant Physiol (2009) 1.37
The CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation. BMC Genomics (2011) 1.36
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. J Lipid Res (2008) 1.36
Genetic characterization of the bile salt response in Lactobacillus plantarum and analysis of responsive promoters in vitro and in situ in the gastrointestinal tract. J Bacteriol (2004) 1.36
Gene amplification, ABC transporters and cytochrome P450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, Aedes aegypti. PLoS Negl Trop Dis (2012) 1.36
Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury. Exp Neurol (2008) 1.34
Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther (2009) 1.34
Ischemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neurons. Proc Natl Acad Sci U S A (2007) 1.34
Cell wall damage-induced lignin biosynthesis is regulated by a reactive oxygen species- and jasmonic acid-dependent process in Arabidopsis. Plant Physiol (2011) 1.32
A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex. Cell (2008) 1.32
Cytokinin regulates type-A Arabidopsis Response Regulator activity and protein stability via two-component phosphorelay. Plant Cell (2007) 1.32
Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res (2008) 1.32
Identification of a novel oligodendrocyte cell adhesion protein using gene expression profiling. J Neurosci (2006) 1.32
Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer. J Transl Med (2012) 1.31
A homologue of the Aspergillus velvet gene regulates both cephalosporin C biosynthesis and hyphal fragmentation in Acremonium chrysogenum. Appl Environ Microbiol (2007) 1.31
Caste- and development-associated gene expression in a lower termite. Genome Biol (2003) 1.31
Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2. Mol Endocrinol (2007) 1.30
Validation of reference genes for real-time polymerase chain reaction studies in Atlantic salmon. Mar Biotechnol (NY) (2006) 1.30
Evaluation and validation of candidate endogenous control genes for real-time quantitative PCR studies of breast cancer. BMC Mol Biol (2007) 1.29
Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat. Plant Physiol (2011) 1.29
The response of Thalassiosira pseudonana to long-term exposure to increased CO2 and decreased pH. PLoS One (2011) 1.28
Myosin, transgelin, and myosin light chain kinase: expression and function in asthma. Am J Respir Crit Care Med (2008) 1.27
Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis. Gastroenterology (2011) 1.25
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol (2000) 29.28
Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y) (1993) 22.41
Housekeeping genes as internal standards: use and limits. J Biotechnol (1999) 19.05
A novel method for real time quantitative RT-PCR. Genome Res (1996) 15.83
The LightCycler: a microvolume multisample fluorimeter with rapid temperature control. Biotechniques (1997) 11.94
Developments in quantitative PCR. Clin Chem Lab Med (1998) 8.72
Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A (1992) 8.24
Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells. FASEB J (1994) 8.03
Regulation of hypoxanthine phosphoribosyltransferase, glyceraldehyde-3-phosphate dehydrogenase and beta-actin mRNA expression in porcine immune cells and tissues. Anim Biotechnol (1998) 7.98
Comparison of glyceraldehyde-3-phosphate dehydrogenase and 28S-ribosomal RNA gene expression as RNA loading controls for northern blot analysis of cell lines of varying malignant potential. Anal Biochem (1994) 7.81
Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma. Oncol Rep (1998) 7.75
Evaluation of RNA isolation methods and reference genes for RT-PCR analyses of rare target RNA. Clin Chem Lab Med (2000) 7.68
Quantification of insulin-like growth factor-1 (IGF-1) mRNA: development and validation of an internally standardised competitive reverse transcription-polymerase chain reaction. Exp Clin Endocrinol Diabetes (1998) 7.66
Stimulation of glyceraldehyde-3-phosphate dehydrogenase mRNA levels by endogenous nitric oxide in cytokine-activated endothelium. Biochem Biophys Res Commun (1995) 7.57
The PCR plateau phase - towards an understanding of its limitations. Biochim Biophys Acta (2000) 4.88
Comparative study of different standardization concepts in quantitative competitive reverse transcription-PCR assays. J Clin Microbiol (1998) 2.68
Real-time fluorescence detection of a single DNA molecule. Biotechniques (1998) 2.47
Quantification of mRNA by polymerase chain reaction (PCR) using an internal standard and a nonradioactive detection method. Methods Mol Biol (1998) 2.39
Analysis of gene expression in single oocytes and embryos by real-time rapid cycle fluorescence monitored RT-PCR. Mol Hum Reprod (1999) 2.24
Sustainable diets for the future: Can we contribute to reducing greenhouse gas emissions by eating a healthy diet? Am J Clin Nutr (2012) 3.54
Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis. Mol Nutr Food Res (2011) 1.49
Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way--a randomized-controlled human intervention trial. Mol Nutr Food Res (2012) 1.43
Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum. Am J Clin Nutr (2008) 1.36
Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex. Am J Clin Nutr (2008) 1.26
A decrease in physical activity affects appetite, energy, and nutrient balance in lean men feeding ad libitum. Am J Clin Nutr (2004) 1.20
The effect of an incremental increase in exercise on appetite, eating behaviour and energy balance in lean men and women feeding ad libitum. Br J Nutr (2008) 1.10
Folate in pregnancy and imprinted gene and repeat element methylation in the offspring. Am J Clin Nutr (2012) 1.04
Effect of a tomato-rich diet on markers of cardiovascular disease risk in moderately overweight, disease-free, middle-aged adults: a randomized controlled trial. Am J Clin Nutr (2012) 0.98
The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation. Genes Nutr (2008) 0.96
In vitro anti-platelet effects of simple plant-derived phenolic compounds are only found at high, non-physiological concentrations. Mol Nutr Food Res (2011) 0.88
Epigenetic status in the offspring of spontaneous and assisted conception. Hum Reprod (2014) 0.87
An evaluation of the IDEEA™ activity monitor for estimating energy expenditure. Br J Nutr (2012) 0.85
Effects of a high-protein, low-carbohydrate v. high-protein, moderate-carbohydrate weight-loss diet on antioxidant status, endothelial markers and plasma indices of the cardiometabolic profile. Br J Nutr (2011) 0.84
Vitamin D in pregnancy at high latitude in Scotland. Br J Nutr (2012) 0.82
Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats--a proteomics and network analysis approach. Mol Nutr Food Res (2012) 0.81
DNA methyltransferase candidate polymorphisms, imprinting methylation, and birth outcome. PLoS One (2013) 0.81
Extra virgin olive oils increase hepatic fat accumulation and hepatic antioxidant protein levels in APOE-/- mice. J Proteome Res (2007) 0.81
Evaluating energy intake measurement in free-living subjects: when to record and for how long? Public Health Nutr (2009) 0.80
Aorta protein networks in marginal and acute zinc deficiency. Proteomics (2008) 0.79
Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis. Mol Nutr Food Res (2012) 0.78
Exploratory analysis of multiple omics datasets using the adjusted RV coefficient. Stat Appl Genet Mol Biol (2011) 0.78
Inter-pregnancy weight change impacts placental weight and is associated with the risk of adverse pregnancy outcomes in the second pregnancy. BMC Pregnancy Childbirth (2014) 0.78
Postprandial cell defense system responses to meal formulations: stratification through gene expression profiling. Mol Nutr Food Res (2014) 0.76
Supplementation with a 9c,11t-rich conjugated linoleic acid blend shows no clear inhibitory effects on platelet function in healthy subjects at low and moderate cardiovascular risk: a randomized controlled trial. Mol Nutr Food Res (2015) 0.76
Effects of wheat and oat-based whole grain foods on serum lipoprotein size and distribution in overweight middle aged people: a randomised controlled trial. PLoS One (2013) 0.75
Reply to I Hawkins and J Sabaté. Am J Clin Nutr (2013) 0.75
Influence of organically or conventionally produced wheat on health, performance and mycotoxin residues in tissues and bile of growing pigs. Arch Anim Nutr (2005) 0.75
Effect of supplementation with an 80:20 cis9,trans11 conjugated linoleic acid blend on the human platelet proteome. Mol Nutr Food Res (2012) 0.75