Published in Pain on April 01, 2002
Progress in genetic studies of pain and analgesia. Annu Rev Pharmacol Toxicol (2009) 1.43
Pain genes. PLoS Genet (2008) 1.23
Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors. Pain (2010) 1.22
Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction. Nat Neurosci (2011) 1.13
The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test. Pain (2009) 0.92
Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mamm Genome (2014) 0.91
Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors. Mol Pain (2010) 0.86
Genomic loci and candidate genes underlying inflammatory nociception. Pain (2010) 0.83
Inter-strain differences of serotonergic inhibitory pain control in inbred mice. Mol Pain (2010) 0.82
Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin. PLoS One (2010) 0.77
The genetics of pain and analgesia in laboratory animals. Methods Mol Biol (2010) 0.76
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Social modulation of pain as evidence for empathy in mice. Science (2006) 5.32
Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol Behav (2005) 4.79
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2010) 4.56
Coding of facial expressions of pain in the laboratory mouse. Nat Methods (2010) 4.47
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Studying sex and gender differences in pain and analgesia: a consensus report. Pain (2007) 3.58
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards. Pain (2008) 3.08
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A (2006) 3.04
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. J Clin Invest (2009) 2.96
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity (2011) 2.49
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. J Exp Med (2009) 2.38
SNPs matter: impact on detection of differential expression. Nat Methods (2007) 2.35
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci U S A (2003) 2.29
Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J Neurosci (2007) 2.28
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med (2012) 2.25
The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain (2005) 2.23
Genomic dissection of behavioral maturation in the honey bee. Proc Natl Acad Sci U S A (2006) 2.16
Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science (2004) 2.15
Sex differences in pain and analgesia: the role of gonadal hormones. Eur J Pain (2004) 2.11
Ontogeny and phylogeny of facial expression of pain. Pain (2015) 2.04
The Rat Grimace Scale: a partially automated method for quantifying pain in the laboratory rat via facial expressions. Mol Pain (2011) 2.01
Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neurosci Biobehav Rev (2002) 2.00
The Songbird Neurogenomics (SoNG) Initiative: community-based tools and strategies for study of brain gene function and evolution. BMC Genomics (2008) 1.93
Influences of laboratory environment on behavior. Nat Neurosci (2002) 1.92
Honey bee aggression supports a link between gene regulation and behavioral evolution. Proc Natl Acad Sci U S A (2009) 1.91
Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice. J Neurosci (2011) 1.88
Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse. Pain (2006) 1.83
Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2006) 1.81
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. Mamm Genome (2007) 1.75
From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase. Proc Natl Acad Sci U S A (2007) 1.74
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
How replicable are mRNA expression QTL? Mamm Genome (2006) 1.71
Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice. J Am Assoc Lab Anim Sci (2012) 1.68
Remote optogenetic activation and sensitization of pain pathways in freely moving mice. J Neurosci (2013) 1.62
Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity. Pain (2002) 1.61
Increasing placebo responses over time in U.S. clinical trials of neuropathic pain. Pain (2015) 1.55
Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis. Mamm Genome (2004) 1.53
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. J Clin Invest (2010) 1.53
T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis. J Immunol (2008) 1.52
Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis. Blood (2011) 1.50
The protective effect of 17beta-estradiol on experimental autoimmune encephalomyelitis is mediated through estrogen receptor-alpha. Am J Pathol (2003) 1.49
Host genetic and environmental effects on mouse intestinal microbiota. ISME J (2012) 1.47
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Hum Mol Genet (2005) 1.46
Complex-trait genetics: emergence of multivariate strategies. Nat Rev Neurosci (2002) 1.46
Discrete molecular states in the brain accompany changing responses to a vocal signal. Proc Natl Acad Sci U S A (2009) 1.46
Progress in genetic studies of pain and analgesia. Annu Rev Pharmacol Toxicol (2009) 1.43
Inferring gene transcriptional modulatory relations: a genetical genomics approach. Hum Mol Genet (2005) 1.43
The complexity of alcohol drinking: studies in rodent genetic models. Behav Genet (2010) 1.41
Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition. J Bone Miner Res (2012) 1.41
Extracting gene networks for low-dose radiation using graph theoretical algorithms. PLoS Comput Biol (2006) 1.41
Reconstructing generalized logical networks of transcriptional regulation in mouse brain from temporal gene expression data. EURASIP J Bioinform Syst Biol (2009) 1.41
Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome (2005) 1.41
Infusion system carrier flow perturbations and dead-volume: large effects on drug delivery in vitro and hemodynamic responses in a swine model. Anesth Analg (2015) 1.39
GeneWeaver: a web-based system for integrative functional genomics. Nucleic Acids Res (2011) 1.39
Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes. Proc Natl Acad Sci U S A (2009) 1.38
A procedure to produce high alcohol intake in mice. Psychopharmacology (Berl) (2004) 1.38
Patterns of pain: meta-analysis of microarray studies of pain. Pain (2011) 1.38
On finding bicliques in bipartite graphs: a novel algorithm and its application to the integration of diverse biological data types. BMC Bioinformatics (2014) 1.35
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
Genetic variation in morphine analgesic tolerance: a survey of 11 inbred mouse strains. Pharmacol Biochem Behav (2002) 1.34
Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene. J Neurosci (2002) 1.33
Identification of Bphs, an autoimmune disease locus, as histamine receptor H1. Science (2002) 1.33
Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. PLoS One (2008) 1.33
Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. Proc Natl Acad Sci U S A (2005) 1.33
Expression profiling soybean response to Pseudomonas syringae reveals new defense-related genes and rapid HR-specific downregulation of photosynthesis. Mol Plant Microbe Interact (2005) 1.32
The Pain Genes Database: An interactive web browser of pain-related transgenic knockout studies. Pain (2007) 1.31
Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (2007) 1.29
Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunol Rev (2008) 1.29
Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: a comparison of selective and combined endothelin receptor blockade. Circulation (2004) 1.27
The PhenoGen informatics website: tools for analyses of complex traits. BMC Genet (2007) 1.25
Mapping quantitative trait loci that influence femoral cross-sectional area in mice. J Bone Miner Res (2002) 1.24
Histamine receptor H1 is required for TCR-mediated p38 MAPK activation and optimal IFN-gamma production in mice. J Clin Invest (2007) 1.23
Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells. J Immunol (2008) 1.23
Modulation of mechanical and thermal nociceptive sensitivity in the laboratory mouse by behavioral state. J Pain (2007) 1.21
Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse. J Neurosci (2010) 1.21
Ontological Discovery Environment: a system for integrating gene-phenotype associations. Genomics (2009) 1.21
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains. Life Sci (2004) 1.19
Susceptibility to anthrax lethal toxin is controlled by three linked quantitative trait loci. Am J Pathol (2003) 1.18
Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection. J Immunol (2008) 1.15
The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family. J Immunol (2010) 1.15
Genetics of experimental allergic encephalomyelitis supports the role of T helper cells in multiple sclerosis pathogenesis. Ann Neurol (2011) 1.12
A three-dimensional examination of the planar nature of the golf swing. J Sports Sci (2005) 1.11
Social approach to pain in laboratory mice. Soc Neurosci (2009) 1.11
Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. Proc Biol Sci (2004) 1.10
The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease. Genome Res (2013) 1.10
Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor. Anesthesiology (2010) 1.08
Transcriptomics comparison between porcine adipose and bone marrow mesenchymal stem cells during in vitro osteogenic and adipogenic differentiation. PLoS One (2012) 1.08