Published in G3 (Bethesda) on February 01, 2012
The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics (2012) 3.84
Genome-wide association studies in mice. Nat Rev Genet (2012) 1.75
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda) (2012) 1.35
Status and access to the Collaborative Cross population. Mamm Genome (2012) 1.32
Ten years of the Collaborative Cross. Genetics (2012) 1.22
High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes Brain Behav (2013) 1.12
The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis. Mamm Genome (2014) 1.09
Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse. Mamm Genome (2012) 1.08
Mouse phenome database. Nucleic Acids Res (2013) 1.08
Genome-wide association mapping of blood cell traits in mice. Mamm Genome (2013) 1.01
Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population. Mamm Genome (2014) 0.94
Controlling complexity: the clinical relevance of mouse complex genetics. Eur J Hum Genet (2013) 0.92
Using the emerging Collaborative Cross to probe the immune system. Genes Immun (2013) 0.91
Susceptibility to Klebsiella pneumonaie infection in collaborative cross mice is a complex trait controlled by at least three loci acting at different time points. BMC Genomics (2014) 0.90
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice. BMC Genomics (2016) 0.88
Genotype is an important determinant factor of host susceptibility to periodontitis in the Collaborative Cross and inbred mouse populations. BMC Genet (2013) 0.88
Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung. Genetics (2014) 0.87
Contrasting genetic architectures in different mouse reference populations used for studying complex traits. Genome Res (2015) 0.86
Integrative genetic analysis of allergic inflammation in the murine lung. Am J Respir Cell Mol Biol (2014) 0.84
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. PLoS Genet (2015) 0.84
Bayesian modeling of haplotype effects in multiparent populations. Genetics (2014) 0.83
Informatics resources for the Collaborative Cross and related mouse populations. Mamm Genome (2015) 0.81
Quantitative trait Loci for resistance to the congenital nephropathy in tensin 2-deficient mice. PLoS One (2014) 0.81
QTL mapping in outbred populations: successes and challenges. Physiol Genomics (2013) 0.79
Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression. G3 (Bethesda) (2014) 0.79
Plethysmography Phenotype QTL in Mice Before and After Allergen Sensitization and Challenge. G3 (Bethesda) (2016) 0.78
Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database. Mamm Genome (2015) 0.77
A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. BMC Genomics (2015) 0.77
Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. BMC Genomics (2015) 0.77
Splicing landscape of the eight collaborative cross founder strains. BMC Genomics (2015) 0.76
Systems biology: A tool for charting the antiviral landscape. Virus Res (2016) 0.75
Exploiting Gene-Expression Deconvolution to Probe the Genetics of the Immune System. PLoS Comput Biol (2016) 0.75
Predictors of hemoglobin variability in a population of weaning age (3- to 4-month old) rhesus monkeys. Am J Primatol (2013) 0.75
Dissecting the Effect of Genetic Variation on the Hepatic Expression of Drug Disposition Genes across the Collaborative Cross Mouse Strains. Front Genet (2016) 0.75
Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1. Genetics (2017) 0.75
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics (2006) 87.59
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet (2006) 9.87
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Evidence based selection of housekeeping genes. PLoS One (2007) 7.90
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet (2009) 6.83
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
A method for fine mapping quantitative trait loci in outbred animal stocks. Proc Natl Acad Sci U S A (2000) 5.46
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci U S A (2008) 5.27
Statistical methods for mapping quantitative trait loci from a dense set of markers. Genetics (1999) 5.05
Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat Genet (2010) 4.36
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics (2012) 3.84
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
Sequence-based characterization of structural variation in the mouse genome. Nature (2011) 3.48
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature (2001) 3.24
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol (2010) 2.95
Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions. Int J Parasitol (2004) 2.92
Genetic and environmental causes of variation in basal levels of blood cells. Twin Res (1999) 2.36
Mapping in structured populations by resample model averaging. Genetics (2009) 2.30
Using progenitor strain information to identify quantitative trait nucleotides in outbred mice. Genetics (2005) 1.89
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
Prospects for association mapping in classical inbred mouse strains. Genetics (2007) 1.71
Multiple loci are associated with white blood cell phenotypes. PLoS Genet (2011) 1.65
Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection. Genome Res (2011) 1.55
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet (2011) 1.45
Efficient genome ancestry inference in complex pedigrees with inbreeding. Bioinformatics (2010) 1.40
Sequence variants in three loci influence monocyte counts and erythrocyte volume. Am J Hum Genet (2009) 1.28
Complex signatures of selection and gene conversion in the duplicated globin genes of house mice. Genetics (2007) 1.16
The primary structure of genetic variants of mouse hemoglobin. Biochem Genet (1982) 1.13
Evidence for linkage of red blood cell size and count: genome-wide scans in the Framingham Heart Study. Am J Hematol (2007) 1.12
Quantitative trait loci regulating relative lymphocyte proportions in mouse peripheral blood. Blood (2002) 1.00
At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. Genomics (1998) 0.98
Mouse haemoglobin beta chains. Comparative sequence data on adult major and minor beta chains from two species, Mus musculus and Mus cervicolor. Biochem J (1976) 0.98
Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood (2010) 0.92
Evolution of the mouse beta-globin genes: a recent gene conversion in the Hbbs haplotype. Mol Biol Evol (1985) 0.92
Quantitative trait locus mapping of susceptibilities to butylated hydroxytoluene-induced lung tumor promotion and pulmonary inflammation in CXB mice. Carcinogenesis (2002) 0.90
Quantitative trait loci for porcine baseline erythroid traits at three growth ages in a White Duroc x Erhualian F(2) resource population. Mamm Genome (2008) 0.89
Quantitative trait loci for steady-state platelet count in mice. Mamm Genome (2004) 0.89
Quantitative trait loci for baseline erythroid traits. Mamm Genome (2006) 0.88
Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume. Mamm Genome (2005) 0.88
Physiological variation of mouse haemoglobins. Proc R Soc Lond B Biol Sci (1983) 0.87
Characterization of LRRFIP1. Biochem Cell Biol (2010) 0.87
Colocalization of mouse autoimmune diabetes loci Idd21.1 and Idd21.2 with IDDM6 (human) and Iddm3 (rat). Diabetes (2005) 0.86
Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy. J Immunol (2005) 0.82
Function, expression and localization of annexin A7 in platelets and red blood cells: insights derived from an annexin A7 mutant mouse. BMC Biochem (2003) 0.82
Oxygen association-dissociation and stability analysis on mouse hemoglobins with mutant alpha- and beta-globins. Genetics (1992) 0.81
Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7. Pflugers Arch (2010) 0.81
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A (2002) 20.48
International network of cancer genome projects. Nature (2010) 20.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
A HapMap harvest of insights into the genetics of common disease. J Clin Invest (2008) 18.31
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Replicating genotype-phenotype associations. Nature (2007) 16.11
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Policy: NIH plans to enhance reproducibility. Nature (2014) 15.71
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature (2003) 12.10
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 10.49
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03
The path to personalized medicine. N Engl J Med (2010) 9.87
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
Policy: NIH to balance sex in cell and animal studies. Nature (2014) 9.15
Ethics. Identifiability in genomic research. Science (2007) 9.08
A mouse for all reasons. Cell (2007) 9.01
The family history--more important than ever. N Engl J Med (2004) 8.35
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
The knockout mouse project. Nat Genet (2004) 7.80
Statistical tests for differential expression in cDNA microarray experiments. Genome Biol (2003) 7.65
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2004) 7.55
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Variation in gene expression within and among natural populations. Nat Genet (2002) 7.19
NIH Molecular Libraries Initiative. Science (2004) 7.04
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays. Nat Methods (2006) 6.25
Heritable individual-specific and allele-specific chromatin signatures in humans. Science (2010) 5.94
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing. Genome Res (2010) 5.76
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res (2005) 5.71
Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics (2005) 5.57
Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med (2008) 5.34
MicroRNA target site polymorphisms and human disease. Trends Genet (2008) 5.32
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A (2004) 4.85
Genomic medicine--a primer. N Engl J Med (2002) 4.77
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
On the subspecific origin of the laboratory mouse. Nat Genet (2007) 4.68
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Genes, environment and the value of prospective cohort studies. Nat Rev Genet (2006) 4.33
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res (2006) 4.15
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Human laminopathies: nuclei gone genetically awry. Nat Rev Genet (2006) 3.89
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci U S A (2006) 3.86
New models for large prospective studies: is there a better way? Am J Epidemiol (2012) 3.85
NIH basics. Science (2012) 3.82
Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2005) 3.64
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
Research priorities. The NIH BRAIN Initiative. Science (2013) 3.61
The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet (2007) 3.55
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Genomic medicine--an updated primer. N Engl J Med (2010) 3.48
Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. Proc Natl Acad Sci U S A (2004) 3.41
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
The genome gets personal--almost. JAMA (2008) 3.28
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Keeping pace with the times--the Genetic Information Nondiscrimination Act of 2008. N Engl J Med (2008) 3.22
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21