Published in Science on May 10, 2002
Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women. Nat Med (2012) 5.20
Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol (2009) 4.11
Genetics of mammalian meiosis: regulation, dynamics and impact on fertility. Nat Rev Genet (2010) 2.58
Bisphenol A exposure in utero disrupts early oogenesis in the mouse. PLoS Genet (2007) 2.33
Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors. Curr Biol (2011) 2.30
Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Mol Cell Biol (2003) 1.68
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet (2007) 1.68
Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes. Am J Hum Genet (2004) 1.67
PRC1 coordinates timing of sexual differentiation of female primordial germ cells. Nature (2013) 1.65
Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew. Curr Opin Pediatr (2009) 1.65
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. J Cell Biol (2007) 1.62
Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis. J Cell Biol (2006) 1.60
Chromosome-wide regulation of meiotic crossover formation in Caenorhabditis elegans requires properly assembled chromosome axes. Genetics (2004) 1.60
Meiotic origins of maternal age-related aneuploidy. Biol Reprod (2012) 1.52
Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis. Science (2003) 1.51
Cohesin Smc1beta determines meiotic chromatin axis loop organization. J Cell Biol (2008) 1.46
Cohesin component dynamics during meiotic prophase I in mammalian oocytes. Chromosome Res (2004) 1.43
SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination. J Cell Biol (2007) 1.43
Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet (2010) 1.42
The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility. EMBO J (2011) 1.34
A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility. PLoS Genet (2011) 1.34
Age-related aneuploidy through cohesion exhaustion. EMBO Rep (2012) 1.31
Telomere attachment, meiotic chromosome condensation, pairing, and bouquet stage duration are modified in spermatocytes lacking axial elements. Mol Biol Cell (2003) 1.26
Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl. RNA (2007) 1.24
A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS Biol (2007) 1.19
Dissecting the mammalian synaptonemal complex using targeted mutations. Chromosome Res (2007) 1.18
DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary. Dev Biol (2011) 1.18
Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase. Mol Cell Biol (2003) 1.17
Inadequate histone deacetylation during oocyte meiosis causes aneuploidy and embryo death in mice. Proc Natl Acad Sci U S A (2006) 1.16
Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes. Chromosoma (2004) 1.14
Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila oocytes. PLoS Genet (2008) 1.12
Meiotic synapsis proceeds from a limited number of subtelomeric sites in the human male. Am J Hum Genet (2005) 1.09
Irregular telomeres impair meiotic synapsis and recombination in mice. Proc Natl Acad Sci U S A (2004) 1.09
Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes. J Cell Biol (2006) 1.07
Mutant meiotic chromosome core components in mice can cause apparent sexual dimorphic endpoints at prophase or X-Y defective male-specific sterility. Chromosoma (2005) 1.02
LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary. Stem Cells Dev (2012) 1.01
Shaping meiotic prophase chromosomes: cohesins and synaptonemal complex proteins. Chromosoma (2006) 1.00
Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice. Proc Natl Acad Sci U S A (2014) 0.97
Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis. Chromosoma (2009) 0.96
Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am J Hum Genet (2008) 0.96
Isolation of small SSEA-4-positive putative stem cells from the ovarian surface epithelium of adult human ovaries by two different methods. Biomed Res Int (2013) 0.96
Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice. Proc Natl Acad Sci U S A (2009) 0.95
A molecular model for the role of SYCP3 in meiotic chromosome organisation. Elife (2014) 0.95
Regulation of the meiotic prophase I to metaphase I transition in mouse spermatocytes. Chromosoma (2008) 0.94
Altered cohesin gene dosage affects Mammalian meiotic chromosome structure and behavior. PLoS Genet (2013) 0.92
Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes. Proc Natl Acad Sci U S A (2012) 0.91
The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse. PLoS Genet (2013) 0.91
Max is a repressor of germ cell-related gene expression in mouse embryonic stem cells. Nat Commun (2013) 0.91
SLXL1, a novel acrosomal protein, interacts with DKKL1 and is involved in fertilization in mice. PLoS One (2011) 0.89
The role of spermatogonially expressed germ cell-specific genes in mammalian meiosis. Chromosome Res (2007) 0.89
Meiotic recombination and male infertility: from basic science to clinical reality? Asian J Androl (2011) 0.87
Male infertility and its causes in human. Adv Urol (2011) 0.87
Germline mosaicism does not explain the maternal age effect on trisomy. Am J Med Genet A (2013) 0.86
In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells. PLoS One (2009) 0.85
Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. PLoS Genet (2014) 0.84
Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes. Dev Biol (2009) 0.84
Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. Mol Cell Biol (2011) 0.82
Failure of homologous synapsis and sex-specific reproduction problems. Front Genet (2012) 0.81
Effect of Rat Medicated Serum Containing Zuo Gui Wan and/or You Gui Wan on the Differentiation of Stem Cells Derived from Human First Trimester Umbilical Cord into Oocyte-Like Cells In Vitro. Evid Based Complement Alternat Med (2015) 0.81
Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice. Cell Div (2006) 0.81
Structural insight into the central element assembly of the synaptonemal complex. Sci Rep (2014) 0.81
Meiotic exchange and segregation in female mice heterozygous for paracentric inversions. Genetics (2004) 0.80
The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem (2015) 0.80
Altered distribution of MLH1 foci is associated with changes in cohesins and chromosome axis compaction in an asynaptic mutant of tomato. Chromosoma (2012) 0.79
Chromosomal instability in mammalian pre-implantation embryos: potential causes, detection methods, and clinical consequences. Cell Tissue Res (2015) 0.79
Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis. PLoS One (2011) 0.78
Pairing, connecting, exchanging, pausing and pulling chromosomes. EMBO Rep (2005) 0.78
Bone morphogenetic protein 2 promotes primordial follicle formation in the ovary. Sci Rep (2015) 0.78
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. PLoS One (2014) 0.77
The X and Y chromosome in meiosis: how and why they keep silent. Asian J Androl (2011) 0.77
Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro. Int J Mol Med (2015) 0.77
The T657C polymorphism on the SYCP3 gene is associated with recurrent pregnancy loss. J Assist Reprod Genet (2014) 0.77
Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics (2013) 0.76
Essential Role for Polycomb Group Protein Pcgf6 in Embryonic Stem Cell Maintenance and a Noncanonical Polycomb Repressive Complex 1 (PRC1) Integrity. J Biol Chem (2017) 0.76
Single-molecule observation of DNA compaction by meiotic protein SYCP3. Elife (2017) 0.75
Telomere homeostasis in mammalian germ cells: a review. Chromosoma (2015) 0.75
Is there a role for DAZL in human female fertility? Mol Hum Reprod (2016) 0.75
Role of polycomb group protein cbx2/m33 in meiosis onset and maintenance of chromosome stability in the Mammalian germline. Genes (Basel) (2011) 0.75
Solving the apparent diversity-accuracy dilemma of recommender systems. Proc Natl Acad Sci U S A (2010) 3.98
Noninvasive in vivo imaging of pancreatic islet cell biology. Nat Med (2008) 2.41
Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation. Genes Dev (2005) 2.38
Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature (2008) 2.24
Age-related meiotic segregation errors in mammalian oocytes are preceded by depletion of cohesin and Sgo2. Curr Biol (2010) 2.17
Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope. Proc Natl Acad Sci U S A (2007) 1.63
Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis. J Cell Sci (2005) 1.62
Bi-orientation of achiasmatic chromosomes in meiosis I oocytes contributes to aneuploidy in mice. Nat Genet (2007) 1.47
Cohesin Smc1beta determines meiotic chromatin axis loop organization. J Cell Biol (2008) 1.46
Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. Stem Cells (2010) 1.44
A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes. Exp Cell Res (2009) 1.41
Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex. J Cell Sci (2006) 1.39
RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis. Nat Genet (2013) 1.38
A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility. PLoS Genet (2011) 1.34
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. J Neurosci (2007) 1.34
Meiotic failure in male mice lacking an X-linked factor. Genes Dev (2008) 1.33
Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod (2007) 1.32
Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis. Mol Endocrinol (2006) 1.30
Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. PLoS Genet (2012) 1.28
SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division. J Cell Sci (2005) 1.27
Telomere attachment, meiotic chromosome condensation, pairing, and bouquet stage duration are modified in spermatocytes lacking axial elements. Mol Biol Cell (2003) 1.26
Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats. J Cardiovasc Pharmacol (2007) 1.25
Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. PLoS Genet (2012) 1.22
Cohesin SMC1beta protects telomeres in meiocytes. J Cell Biol (2009) 1.22
Mouse embryonic stem cells form follicle-like ovarian structures but do not progress through meiosis. Stem Cells (2006) 1.21
Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes. Genes Dev (2014) 1.20
Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex. J Cell Sci (2008) 1.16
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues. Mol Cell Proteomics (2003) 1.15
Diagnostics as essential tools for containing antibacterial resistance. Drug Resist Updat (2011) 1.12
Behaviors of susceptible-infected epidemics on scale-free networks with identical infectivity. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 1.10
Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes. J Cell Biol (2006) 1.07
Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning. J Biol Chem (2010) 1.03
Meiotic interference among MLH1 foci requires neither an intact axial element structure nor full synapsis. J Cell Sci (2007) 1.02
Mutant meiotic chromosome core components in mice can cause apparent sexual dimorphic endpoints at prophase or X-Y defective male-specific sterility. Chromosoma (2005) 1.02
Meiosis in mice without a synaptonemal complex. PLoS One (2011) 1.01
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing. Genes Dev (2013) 1.01
The fate of mosaic aneuploid embryos during mouse development. Dev Biol (2005) 1.00
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS Genet (2012) 0.99
BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci (2009) 0.98
Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling. Mol Syst Biol (2013) 0.96
Accelerated discovery of novel protein function in cultured human cells. Mol Cell Proteomics (2005) 0.96
Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration. Hum Mol Genet (2008) 0.95
A novel approach for evaluating the efficiency of siRNAs on protein levels in cultured cells. Nucleic Acids Res (2004) 0.93
Phenylenediamine-based FeN(x)/C catalyst with high activity for oxygen reduction in acid medium and its active-site probing. J Am Chem Soc (2014) 0.92
Thorough validation of siRNA-induced cell death phenotypes defines new anti-apoptotic protein. Nucleic Acids Res (2006) 0.91
Arterial baroreflex: a novel target for preventing stroke in rat hypertension. Stroke (2007) 0.89
Information filtering based on transferring similarity. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.88
Arterial baroreflex function is an important determinant of acute cerebral ischemia in rats with middle cerebral artery occlusion. Life Sci (2008) 0.88
Coxsackievirus and adenovirus receptor is up-regulated in migratory germ cells during passage of the blood-testis barrier. Endocrinology (2007) 0.87
Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice. Neurogenetics (2010) 0.85
Composition analysis of colored dissolved organic matter in Taihu Lake based on three dimension excitation-emission fluorescence matrix and PARAFAC model, and the potential application in water quality monitoring. J Environ Sci (China) (2007) 0.84
The mitochondrial alternative oxidase pathway protects the photosynthetic apparatus against photodamage in Rumex K-1 leaves. BMC Plant Biol (2012) 0.84
Effects of solid-state yeast treatment on the antioxidant properties and protein and fiber compositions of common hard wheat bran. J Agric Food Chem (2007) 0.84
Serine protease inhibitor A3 in atherosclerosis and aneurysm disease. Int J Mol Med (2012) 0.84
Local RAS and inflammatory factors are involved in cardiovascular hypertrophy in spontaneously hypertensive rats. Pharmacol Res (2008) 0.84
Coating gigaporous polystyrene microspheres with cross-linked poly(vinyl alcohol) hydrogel as a rapid protein chromatography matrix. ACS Appl Mater Interfaces (2014) 0.83
Normal sexual development and fertility in testatin knockout mice. Mol Cell Biol (2005) 0.83
Sexually dimorphic expression of foxl2 during gametogenesis in scallop Chlamys farreri, conserved with vertebrates. Dev Genes Evol (2012) 0.82
Pressor and non-pressor effects of sodium loading on stroke in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol (2008) 0.81
Arterial baroreflex dysfunction fails to mimic Parkinson's disease in rats. J Pharmacol Sci (2008) 0.81
Effects of long-term treatment with ketanserin on blood pressure variability and end-organ damage in spontaneously hypertensive rats. J Cardiovasc Pharmacol (2003) 0.80
[Effect of cryopreservation of bone marrow stromal cells on periodontal tissue regeneration]. Zhonghua Kou Qiang Yi Xue Za Zhi (2008) 0.79
Effects of long-term treatment with candesartan on organ damages in sinoaortic denervated rats. J Cardiovasc Pharmacol (2003) 0.79
Comparative study on seeding methods of human bone marrow stromal cells in bone tissue engineering. Chin Med J (Engl) (2004) 0.79
Male sex determination and prenatal differentiation of the testis. Endocr Dev (2003) 0.79
Chemical speciation and mobility of heavy metals in municipal solid waste incinerator fly ash. J Environ Sci (China) (2004) 0.78
The acyl-CoA binding protein is required for normal epidermal barrier function in mice. J Lipid Res (2012) 0.78
NovelFam3000--uncharacterized human protein domains conserved across model organisms. BMC Genomics (2006) 0.78
Effects of genotype and environment on the antioxidant properties of hard winter wheat bran. J Agric Food Chem (2006) 0.77
Isolation of the human testatin gene and analysis in patients with abnormal gonadal development. Mol Hum Reprod (2002) 0.77
Importance of blood pressure variability in organ protection in spontaneously hypertensive rats treated with combination of nitrendipine and atenolol. Acta Pharmacol Sin (2002) 0.77
Arthroplasty in patients with extensive femoral head avascular necrosis: Cementless arthroplasty in extensive femoral head necrosis. Int Orthop (2015) 0.77
Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats. CNS Neurosci Ther (2013) 0.76
Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats. CNS Neurosci Ther (2012) 0.76
Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies. Comp Funct Genomics (2004) 0.75
Correction: Do Nobel Laureates Create Prize-Winning Networks? An Analysis of Collaborative Research in Physiology or Medicine. PLoS One (2015) 0.75
Efficacy and Safety of Zhuanggu Joint Capsules in Combination with Celecoxib in Knee Osteoarthritis: A Multi-center, Randomized, Double-blind, Double-dummy, and Parallel Controlled Trial. Chin Med J (Engl) (2016) 0.75
TLR4 polymorphism and periodontitis susceptibility: A meta-analysis. Medicine (Baltimore) (2016) 0.75
[Analysis of the characters of organic matter in water using spectral fluorescence signature and fitting Gaussian]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Purification and renaturation of recombinant human Cu, Zn-SOD by metal-chelating affinity chromatography]. Sheng Wu Gong Cheng Xue Bao (2005) 0.75
[Effect of PLA/starch slow-release carbon source on biological denitrification]. Huan Jing Ke Xue (2014) 0.75
[Application of MALT-CLS method to FTIR quantitative analysis of atmospheric trace gas]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Research of moisture content variation in MSW landfill]. Huan Jing Ke Xue (2013) 0.75
[Laser abduction fluorescence spectrum for aerosol particle measurement]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Simulation and analysis of second-harmonic signal based on tunable diode laser absorption spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi (2013) 0.75
[Inflammatory myofibroblastoma: a case report]. Zhongguo Gu Shang (2013) 0.75
Research on remote sensing of broadband absorbers by using near-infrared diode lasers. Appl Opt (2014) 0.75
[Homology analysis of the extended-V region of the surface proteins in different serotype Streptococcus mutans]. Hua Xi Kou Qiang Yi Xue Za Zhi (2006) 0.75
A high-stringency proteomics concept aimed for generation of antibodies specific for cDNA-encoded proteins. Biotechnol Appl Biochem (2002) 0.75
[Chronic osteomyelitis easily misdiagnosed by giant cell tumors of bone: a case report]. Zhongguo Gu Shang (2013) 0.75
[Remote sensing of seasonal variation in column concentration of atmospheric CO2 and CH4 in Hefei]. Guang Pu Xue Yu Guang Pu Fen Xi (2014) 0.75
Multifocal Osteonecrosis in an Adolescent Patient With Systemic Lupus Erythematosus and Ankle Pain. J Clin Rheumatol (2017) 0.75
[Embryonal rhabdomyosarcoma of adult lower leg with bone marrow invasion: a case report]. Zhongguo Gu Shang (2015) 0.75
[The study of remote sensing CH4 concentration based on tunable diode laser absorption spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Revisional surgery for nonstandard gastric bypass: a case report]. Nan Fang Yi Ke Da Xue Xue Bao (2017) 0.75
Single-vector three-frame expression systems for affinity-tagged proteins. FEMS Microbiol Lett (2002) 0.75
[Second-harmonic detection with tunable diode laser absorption spectroscopy of CO and CO2 at 1.58 microm]. Guang Pu Xue Yu Guang Pu Fen Xi (2006) 0.75
[Analysis of heavy metals distribution characteristics and pollution assessment in agricultural region soils of Huaihe basin]. Guang Pu Xue Yu Guang Pu Fen Xi (2014) 0.75
Hoffa fracture associated with ipsilateral femoral shaft fracture: clinical feature and treatment. Chin J Traumatol (2011) 0.75