Published in Nat Neurosci on June 01, 2002
Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev (2003) 2.59
Early steps in the development of the forebrain. Dev Cell (2004) 2.34
Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation. Proc Natl Acad Sci U S A (2008) 1.87
An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol (2006) 1.76
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid. Mol Cell Neurosci (2010) 1.69
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol (2014) 1.39
Impaired neural development caused by inducible expression of Axin in transgenic mice. Mech Dev (2006) 1.32
Specification of midbrain dopamine neurons from primate pluripotent stem cells. Stem Cells (2012) 1.28
Wnt signaling in eye organogenesis. Organogenesis (2008) 1.21
Models for the generation and interpretation of gradients. Cold Spring Harb Perspect Biol (2009) 1.12
Repression of the hindbrain developmental program by Cdx factors is required for the specification of the vertebrate spinal cord. Development (2007) 1.12
Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Neural Dev (2009) 1.08
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain. Development (2007) 1.07
Integration of canonical and noncanonical Wnt signaling pathways patterns the neuroectoderm along the anterior-posterior axis of sea urchin embryos. PLoS Biol (2013) 1.03
Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2004) 1.02
Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells. Development (2014) 1.00
Inhibition of Wnt/Axin/beta-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity. Development (2004) 0.98
Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation. Stem Cells (2014) 0.97
The prethalamus is established during gastrulation and influences diencephalic regionalization. PLoS Biol (2007) 0.95
Wnt signaling is regulated by endoplasmic reticulum retention. PLoS One (2009) 0.95
Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. PLoS One (2008) 0.95
Developmental mechanisms directing early anterior forebrain specification in vertebrates. Cell Mol Life Sci (2013) 0.94
β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development (2012) 0.93
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
Ectopic activation of the canonical wnt signaling pathway affects ectodermal patterning along the primary axis during larval development in the anthozoan Nematostella vectensis. Dev Biol (2013) 0.92
Neuromesodermal progenitors and the making of the spinal cord. Development (2015) 0.91
Dopaminergic neuronal cluster size is determined during early forebrain patterning. Development (2008) 0.91
Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci (2011) 0.90
Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD. Front Cell Neurosci (2014) 0.89
Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm. PLoS One (2014) 0.87
Mesodermal Wnt signaling organizes the neural plate via Meis3. Development (2010) 0.87
Phylogenetic origins of brain organisers. Scientifica (Cairo) (2012) 0.84
In vitro differentiation of mouse embryonic stem cells into neurons of the dorsal forebrain. Cell Mol Neurobiol (2011) 0.84
Modeling ALS with motor neurons derived from human induced pluripotent stem cells. Nat Neurosci (2016) 0.83
Endogenous WNT signaling regulates hPSC-derived neural progenitor cell heterogeneity and specifies their regional identity. Stem Cell Reports (2014) 0.83
Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells. Mol Cell Neurosci (2011) 0.82
beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region. PLoS One (2010) 0.81
Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes. Semin Cell Dev Biol (2015) 0.80
Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports (2015) 0.79
Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation. Stem Cells Dev (2013) 0.78
MAPK signaling is necessary for neurogenesis in Nematostella vectensis. BMC Biol (2016) 0.78
Choice of either beta-catenin or Groucho/TLE as a co-factor for Xtcf-3 determines dorsal-ventral cell fate of diencephalon during Xenopus development. Dev Genes Evol (2005) 0.77
An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo. Development (2016) 0.76
Epigenetic changes in the developing brain: Effects on behavior. Proc Natl Acad Sci U S A (2015) 0.76
Wnt signals lead cells down the caudal path. Nat Neurosci (2002) 0.75
Multi-compartmental biomaterial scaffolds for patterning neural tissue organoids in models of neurodevelopment and tissue regeneration. J Tissue Eng (2016) 0.75
Differentiation of human pluripotent stem cells into Medial Ganglionic Eminence vs. Caudal Ganglionic Eminence cells. Methods (2015) 0.75
Directed differentiation of embryonic stem cells into motor neurons. Cell (2002) 9.76
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci (2007) 7.77
A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity. Cell (2005) 3.58
Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science (2004) 2.95
Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell (2006) 2.85
A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron (2009) 2.75
Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron (2006) 2.60
Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell (2008) 2.60
Genetic identification of spinal interneurons that coordinate left-right locomotor activity necessary for walking movements. Neuron (2004) 2.54
PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron (2006) 2.48
The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord. Neuron (2002) 2.48
Motor neuron columnar fate imposed by sequential phases of Hox-c activity. Nature (2003) 2.47
Measured motion: searching for simplicity in spinal locomotor networks. Curr Opin Neurobiol (2009) 2.40
Regulation of motor neuron pool sorting by differential expression of type II cadherins. Cell (2002) 2.32
Hox networks and the origins of motor neuron diversity. Curr Top Dev Biol (2009) 2.30
Genetic ablation of V2a ipsilateral interneurons disrupts left-right locomotor coordination in mammalian spinal cord. Neuron (2008) 2.28
Functional properties of motoneurons derived from mouse embryonic stem cells. J Neurosci (2004) 2.27
A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification. Neuron (2006) 2.26
ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools. Neuron (2002) 2.17
Clarke's column neurons as the focus of a corticospinal corollary circuit. Nat Neurosci (2010) 2.13
A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification. Neuron (2003) 2.10
Topographic motor projections in the limb imposed by LIM homeodomain protein regulation of ephrin-A:EphA interactions. Neuron (2003) 1.98
Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents. Neuron (2003) 1.91
Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron (2005) 1.89
Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature (2009) 1.88
Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron (2007) 1.83
An early role for WNT signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. PLoS Biol (2006) 1.76
Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci (2005) 1.76
A role for neuregulin1 signaling in muscle spindle differentiation. Neuron (2002) 1.60
Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit. Cell (2009) 1.59
SnapShot: spinal cord development. Cell (2011) 1.56
A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron (2004) 1.54
Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template. Cell (2011) 1.51
Graded activity of transcription factor Runx3 specifies the laminar termination pattern of sensory axons in the developing spinal cord. Neuron (2006) 1.48
Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation. Cell Stem Cell (2010) 1.42
Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron (2008) 1.41
Early motor neuron pool identity and muscle nerve trajectory defined by postmitotic restrictions in Nkx6.1 activity. Neuron (2008) 1.40
T-cadherin structures reveal a novel adhesive binding mechanism. Nat Struct Mol Biol (2010) 1.37
A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron (2005) 1.33
Specification of dorsal telencephalic character by sequential Wnt and FGF signaling. Nat Neurosci (2003) 1.33
Retinoid receptor signaling in postmitotic motor neurons regulates rostrocaudal positional identity and axonal projection pattern. Neuron (2003) 1.32
Gamma and alpha motor neurons distinguished by expression of transcription factor Err3. Proc Natl Acad Sci U S A (2009) 1.31
Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A (2006) 1.30
Motor neuron position and topographic order imposed by β- and γ-catenin activities. Cell (2011) 1.24
Regulation of motor neuron subtype identity by repressor activity of Mnx class homeodomain proteins. Development (2003) 1.23
Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron (2009) 1.22
An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron (2002) 1.20
Wnt-regulated temporal control of BMP exposure directs the choice between neural plate border and epidermal fate. Development (2009) 1.20
In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells. Exp Neurol (2006) 1.12
Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron (2013) 1.09
Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron (2012) 1.08
Circuits for grasping: spinal dI3 interneurons mediate cutaneous control of motor behavior. Neuron (2013) 1.08
A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development (2010) 1.07
Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets. Neuron (2013) 1.04
Time of exposure to BMP signals plays a key role in the specification of the olfactory and lens placodes ex vivo. Dev Cell (2007) 1.01
Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. PLoS One (2008) 0.95
Specificity of monosynaptic sensory-motor connections imposed by repellent Sema3E-PlexinD1 signaling. Cell Rep (2013) 0.91
Retinoic acid signalling specifies intermediate character in the developing telencephalon. Development (2004) 0.88
Edging toward entelechy in motor control. Neuron (2013) 0.87
Nitric oxide and blood pressure in mice lacking extracellular-superoxide dismutase. Free Radic Res (2002) 0.84
Convergent Wnt and FGF signaling at the gastrula stage induce the formation of the isthmic organizer. Mech Dev (2006) 0.82