Published in Biochem J on August 15, 2002
Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7. Mol Biol Cell (2007) 0.95
The role of serine/threonine protein phosphatases in exocytosis. Biochem J (2003) 0.89
Transcriptome profiling of sexual maturation and mating in the Mediterranean fruit fly, Ceratitis capitata. PLoS One (2012) 0.88
Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1. Cell (2015) 0.84
A simple assay for 3-deoxy-d-manno-octulosonate cytidylyltransferase and its use as a pathway screen. Anal Biochem (2011) 0.80
Negative regulation of MAP kinase signaling in Drosophila by Ptp61F/PTP1B. Mol Genet Genomics (2014) 0.75
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc Natl Acad Sci U S A (2000) 9.02
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell (2000) 6.92
Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. Genes Dev (1994) 2.28
DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Hum Mol Genet (1998) 2.24
Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories. Genes Dev (1996) 2.04
Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell (1996) 1.96
Protein kinases and phosphatases in the Drosophila genome. J Cell Biol (2000) 1.81
The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila. Cell (1996) 1.75
Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog. Science (1990) 1.71
Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo. Neuron (1999) 1.67
Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation. Mol Cell Biol (2000) 1.66
Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. J Med Genet (2000) 1.61
NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice. J Cell Biol (1994) 1.34
A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance. J Biol Chem (1996) 1.26
Regulation of JNK by Src during Drosophila development. Science (2000) 1.18
Tyrosine phosphorylation and axon guidance: of mice and flies. Curr Opin Neurobiol (1997) 1.09
The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton. J Biol Chem (2001) 1.08
Regulated tyrosine phosphorylation at the tips of growth cone filopodia. J Cell Biol (1993) 1.08
Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth. J Neurobiol (1992) 0.96
Protein tyrosine phosphatases in the developing nervous system. Curr Opin Cell Biol (1998) 0.92
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem (2001) 0.91
Oncogenes, Protein Tyrosine Kinases, and Signal Transduction. J Biomed Sci (1994) 0.88
Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo. Development (1998) 0.83
Non-receptor tyrosine kinases in mammalian neurogenesis. Princess Takamatsu Symp (1994) 0.77
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol (2007) 13.99
Dendrite self-avoidance is controlled by Dscam. Cell (2007) 3.96
Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science (2003) 3.81
Identification of a bacterial type III effector family with G protein mimicry functions. Cell (2006) 3.47
Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A (2008) 3.20
Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector. Science (2002) 3.10
Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell (2004) 3.10
Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies. Neuron (2004) 3.04
Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol (2002) 2.93
Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A (2003) 2.92
Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A (2012) 2.90
A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis. Cell (2002) 2.75
The fic domain: regulation of cell signaling by adenylylation. Mol Cell (2009) 2.73
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science (2012) 2.55
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell (2005) 2.36
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A (2007) 2.28
Axonal targeting of olfactory receptor neurons in Drosophila is controlled by Dscam. Neuron (2003) 2.22
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe (2008) 2.21
MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A (2007) 2.19
Dendritic patterning by Dscam and synaptic partner matching in the Drosophila antennal lobe. Nat Neurosci (2006) 2.19
Overview of the Alliance for Cellular Signaling. Nature (2002) 2.15
Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol (2006) 2.09
Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J Biol Chem (2006) 2.04
Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab (2011) 1.97
Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci U S A (2005) 1.90
A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A (2008) 1.85
Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci (2005) 1.81
A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A (2007) 1.80
Secreted protein kinases. Trends Biochem Sci (2012) 1.79
A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen. J Biol Chem (2001) 1.78
The organization and evolution of the dipteran and hymenopteran Down syndrome cell adhesion molecule (Dscam) genes. RNA (2004) 1.76
The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem (2007) 1.72
Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. Mol Cell (2006) 1.71
The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol (2007) 1.67
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem (2001) 1.66
The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol (2007) 1.66
PTEN. Annu Rev Biochem (2014) 1.62
PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease. Trends Cell Biol (2002) 1.62
The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. J Biol Chem (2003) 1.61
Functions of the Yersinia effector proteins in inhibiting host immune responses. Curr Opin Microbiol (2005) 1.57
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem (2007) 1.57
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A (2003) 1.54
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase. Proc Natl Acad Sci U S A (2003) 1.53
Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem (2009) 1.50
Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci (2009) 1.50
Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell (2003) 1.46
Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol (2010) 1.44
Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem (2009) 1.38
The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc Natl Acad Sci U S A (2003) 1.38
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A (2014) 1.35
Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease. J Biol Chem (2001) 1.35
Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol (2007) 1.33
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev (2007) 1.32
Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A (2006) 1.30
Identification of a molecular target for the Yersinia protein kinase A. Mol Cell (2007) 1.29
A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem (2004) 1.26
Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem (2010) 1.25
Yersinia effectors target mammalian signalling pathways. Cell Microbiol (2002) 1.23
Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology (Bethesda) (2011) 1.20
The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem (2005) 1.18
Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem (2011) 1.17
Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem (2011) 1.15
A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem (2009) 1.12
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A (2011) 1.09
The structure and regulation of myotubularin phosphatases. Curr Opin Struct Biol (2005) 1.08
Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem (2012) 1.08
PTEN and myotubularins: families of phosphoinositide phosphatases. Methods Enzymol (2003) 1.07
Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med (2013) 1.04
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A (2002) 1.04
Functional characterization of HFR1, a high-mannose N-glycan-specific wheat lectin induced by Hessian fly larvae. Plant Physiol (2008) 1.02
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A (2008) 0.98
Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A (2011) 0.98
Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades. J Biol Chem (2002) 0.98
Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem (2008) 0.97
Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. J Mol Biol (2011) 0.97
Mad is required for wingless signaling in wing development and segment patterning in Drosophila. PLoS One (2009) 0.97
Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A (2013) 0.97
Phosphoinositide phosphatases: emerging roles as voltage sensors? Mol Interv (2005) 0.95
Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci (2010) 0.94
A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem (2003) 0.92
Pharmacological targeting of the mitochondrial phosphatase PTPMT1. J Pharmacol Exp Ther (2010) 0.92
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem (2001) 0.91
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev (2014) 0.86
Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity. Hum Mol Genet (2011) 0.86
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer (2006) 0.86
Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol (2009) 0.85