Published in Curr Opin Microbiol on February 01, 2005
Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague. Proc Natl Acad Sci U S A (2006) 1.66
Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis. Proc Natl Acad Sci U S A (2008) 1.49
Inflammation and oxidative stress in vertebrate host-parasite systems. Philos Trans R Soc Lond B Biol Sci (2009) 1.46
Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect Immun (2008) 1.44
Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival. PLoS Pathog (2006) 1.36
Modulation of tumor necrosis factor by microbial pathogens. PLoS Pathog (2006) 1.34
Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG. J Mol Biol (2008) 1.26
Yersinia pestis YopJ suppresses tumor necrosis factor alpha induction and contributes to apoptosis of immune cells in the lymph node but is not required for virulence in a rat model of bubonic plague. Infect Immun (2006) 1.23
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. PLoS Pathog (2010) 1.16
Three Yersinia pestis adhesins facilitate Yop delivery to eukaryotic cells and contribute to plague virulence. Infect Immun (2010) 1.11
Host-mediated phosphorylation of type III effector AvrPto promotes Pseudomonas virulence and avirulence in tomato. Plant Cell (2006) 1.10
The Yersinia enterocolitica effector YopP inhibits host cell signalling by inactivating the protein kinase TAK1 in the IL-1 signalling pathway. EMBO Rep (2006) 1.10
Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10. Infect Immun (2007) 1.10
Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms. Infect Immun (2012) 1.08
Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion. Protein Sci (2009) 1.08
Culling of activated CD4 T cells during typhoid is driven by Salmonella virulence genes. J Immunol (2009) 1.04
Kinetics of innate immune response to Yersinia pestis after intradermal infection in a mouse model. Infect Immun (2012) 1.01
Interaction between Yersinia pestis and the host immune system. Infect Immun (2008) 0.98
Immune evasion, immunopathology and the regulation of the immune system. Pathogens (2013) 0.94
Identification of secreted bacterial proteins by noncanonical amino acid tagging. Proc Natl Acad Sci U S A (2013) 0.93
Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways. PLoS One (2008) 0.93
Crystal structure of the Yersinia type III secretion protein YscE. Protein Sci (2005) 0.93
Innate immune response to Anaplasma phagocytophilum contributes to hepatic injury. Clin Vaccine Immunol (2006) 0.92
Discordance in the effects of Yersinia pestis on the dendritic cell functions manifested by induction of maturation and paralysis of migration. Infect Immun (2006) 0.91
Yersinia pestis can bypass protective antibodies to LcrV and activation with gamma interferon to survive and induce apoptosis in murine macrophages. Clin Vaccine Immunol (2009) 0.89
Crystal structure of Yersinia enterocolitica type III secretion chaperone SycT. Protein Sci (2005) 0.86
Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLoS Pathog (2011) 0.85
Host-pathogen interactions: a biological rendez-vous of the infectious nonself and danger models? PLoS Pathog (2006) 0.83
Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague. PLoS Pathog (2015) 0.82
Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system. Acta Crystallogr D Biol Crystallogr (2012) 0.81
Yersinia virulence factors - a sophisticated arsenal for combating host defences. F1000Res (2016) 0.81
Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein. J Biol Chem (2013) 0.81
LcrQ blocks the role of LcrF in regulating the Ysc-Yop type III secretion genes in Yersinia pseudotuberculosis. PLoS One (2014) 0.80
Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection. PLoS Pathog (2012) 0.79
Evasion and interference: intracellular pathogens modulate caspase-dependent inflammatory responses. Nat Rev Microbiol (2016) 0.78
Yersinia pestis and host macrophages: immunodeficiency of mouse macrophages induced by YscW. Immunology (2008) 0.78
A comprehensive study on the role of the Yersinia pestis virulence markers in an animal model of pneumonic plague. Folia Microbiol (Praha) (2011) 0.77
Regulation of Yersinia protein kinase A (YpkA) kinase activity by multisite autophosphorylation and identification of an N-terminal substrate-binding domain in YpkA. J Biol Chem (2014) 0.77
Inactivation of Peroxiredoxin 6 by the Pla Protease of Yersinia pestis. Infect Immun (2015) 0.77
Uncovering an Important Role for YopJ in the Inhibition of Caspase-1 in Activated Macrophages and Promoting Yersinia pseudotuberculosis Virulence. Infect Immun (2016) 0.77
Yersinia type III effectors perturb host innate immune responses. World J Biol Chem (2016) 0.77
Essential role of the SycP chaperone in type III secretion of the YspP effector. J Bacteriol (2008) 0.77
Bacterial effectors target BAK1-associated receptor complexes: One stone two birds. Commun Integr Biol (2010) 0.76
Mechanisms of horizontal cell-to-cell transfer of Wolbachia spp. in Drosophila melanogaster. Appl Environ Microbiol (2017) 0.75
Yersinia enterocolitica inhibits Salmonella enterica serovar Typhimurium and Listeria monocytogenes cellular uptake. Infect Immun (2013) 0.75
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol (2007) 13.99
Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science (2003) 3.81
Identification of a bacterial type III effector family with G protein mimicry functions. Cell (2006) 3.47
Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A (2008) 3.20
Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector. Science (2002) 3.10
Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol (2002) 2.93
Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A (2003) 2.92
Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A (2012) 2.90
A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis. Cell (2002) 2.75
The fic domain: regulation of cell signaling by adenylylation. Mol Cell (2009) 2.73
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science (2012) 2.55
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell (2005) 2.36
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A (2007) 2.28
Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe (2008) 2.21
MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A (2007) 2.19
Overview of the Alliance for Cellular Signaling. Nature (2002) 2.15
Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol (2006) 2.09
Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J Biol Chem (2006) 2.04
Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab (2011) 1.97
Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci U S A (2005) 1.90
A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A (2008) 1.85
Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci (2005) 1.81
A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A (2007) 1.80
Secreted protein kinases. Trends Biochem Sci (2012) 1.79
Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ. Nature (2013) 1.79
A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen. J Biol Chem (2001) 1.78
The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem (2007) 1.72
Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. Mol Cell (2006) 1.71
The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol (2007) 1.67
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem (2001) 1.66
The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol (2007) 1.66
PTEN. Annu Rev Biochem (2014) 1.62
PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease. Trends Cell Biol (2002) 1.62
The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. J Biol Chem (2003) 1.61
The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold. Nature (2010) 1.58
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem (2007) 1.57
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A (2003) 1.54
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase. Proc Natl Acad Sci U S A (2003) 1.53
Identification of F-actin as the dynamic hub in a microbial-induced GTPase polarity circuit. Cell (2012) 1.52
Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem (2009) 1.50
Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci (2009) 1.50
Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell (2003) 1.46
Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol (2010) 1.44
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. Nat Struct Mol Biol (2009) 1.41
Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem (2009) 1.38
The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc Natl Acad Sci U S A (2003) 1.38
Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A (2014) 1.35
Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease. J Biol Chem (2001) 1.35
Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol (2007) 1.33
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev (2007) 1.32
Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A (2006) 1.30
Identification of a molecular target for the Yersinia protein kinase A. Mol Cell (2007) 1.29
A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem (2004) 1.26
Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem (2010) 1.25
Yersinia effectors target mammalian signalling pathways. Cell Microbiol (2002) 1.23
Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology (Bethesda) (2011) 1.20
Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem (2010) 1.19
The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem (2005) 1.18
Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem (2011) 1.17
Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem (2011) 1.15
The enteropathogenic Escherichia coli effector protein EspF decreases sodium hydrogen exchanger 3 activity. Cell Microbiol (2008) 1.14
A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem (2009) 1.12
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A (2011) 1.09
The structure and regulation of myotubularin phosphatases. Curr Opin Struct Biol (2005) 1.08
Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem (2012) 1.08
PTEN and myotubularins: families of phosphoinositide phosphatases. Methods Enzymol (2003) 1.07
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A (2002) 1.04
Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med (2013) 1.04
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A (2008) 0.98
Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A (2011) 0.98
Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades. J Biol Chem (2002) 0.98
Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem (2008) 0.97
Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A (2013) 0.97
Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. J Mol Biol (2011) 0.97
Phosphoinositide phosphatases: emerging roles as voltage sensors? Mol Interv (2005) 0.95
Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci (2010) 0.94
Mimicking GEFs: a common theme for bacterial pathogens. Cell Microbiol (2011) 0.93
A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem (2003) 0.92
Pharmacological targeting of the mitochondrial phosphatase PTPMT1. J Pharmacol Exp Ther (2010) 0.92
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem (2001) 0.91
E. coli secreted protein F promotes EPEC invasion of intestinal epithelial cells via an SNX9-dependent mechanism. Cell Microbiol (2010) 0.88
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev (2014) 0.86
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer (2006) 0.86
Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol (2009) 0.85
Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21. Methods Enzymol (2009) 0.85
YopT is a cysteine protease cleaving Rho family GTPases. Adv Exp Med Biol (2003) 0.84
Correlative light and electron microscopy (CLEM) as a tool to visualize microinjected molecules and their eukaryotic sub-cellular targets. J Vis Exp (2012) 0.83
Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J (2002) 0.83
Phosphorylation of substrates destined for secretion by the Fam20 kinases. Biochem Soc Trans (2013) 0.83
Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. Methods Enzymol (2008) 0.83
Tight junctions and enteropathogenic E. coli. Ann N Y Acad Sci (2009) 0.83
Activation of PAK by a bacterial type III effector EspG reveals alternative mechanisms of GTPase pathway regulation. Small GTPases (2011) 0.82
Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN. FEBS Lett (2004) 0.82
Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. FEBS Lett (2005) 0.82
Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation. J Vasc Surg (2003) 0.82
Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules, contribute to tight junction perturbation and inhibit restoration. Cell Microbiol (2014) 0.82
Microbiology. Bacteria seize control by acetylating host proteins. Science (2006) 0.82
Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification. PLoS One (2012) 0.81
The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons. Neuron (2013) 0.81