Published in FEBS Lett on April 24, 2002
Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci U S A (2006) 6.83
Myosin V: regulation by calcium, calmodulin, and the tail domain. J Cell Biol (2004) 2.40
Structural basis for myosin V discrimination between distinct cargoes. EMBO J (2006) 1.95
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome. J Clin Invest (2002) 1.81
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation. J Clin Invest (2005) 1.75
Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells. Mol Biol Cell (2005) 1.69
Polarized growth and organelle segregation in yeast: the tracks, motors, and receptors. J Cell Biol (2003) 1.62
Identification of an organelle-specific myosin V receptor. J Cell Biol (2003) 1.57
Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes. J Cell Sci (2004) 1.53
Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell (2011) 1.50
Rab proteins and the compartmentalization of the endosomal system. Cold Spring Harb Perspect Biol (2014) 1.40
The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes. Mol Cell Biol (2003) 1.32
Rab27b is associated with fusiform vesicles and may be involved in targeting uroplakins to urothelial apical membranes. Proc Natl Acad Sci U S A (2003) 1.20
A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes. Mol Biol Cell (2006) 1.18
Griscelli syndrome: characterization of a new mutation and rescue of T-cytotoxic activity by retroviral transfer of RAB27A gene. J Clin Immunol (2004) 1.00
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain. Mol Biol Cell (2006) 0.99
Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells. Am J Physiol Lung Cell Mol Physiol (2011) 0.94
Identification and characterization of multiple novel Rab-myosin Va interactions. Mol Biol Cell (2013) 0.94
Myosin V and the endoplasmic reticulum: the connection grows. J Cell Biol (2003) 0.90
Melanosome transfer: it is best to give and receive. Curr Opin Cell Biol (2014) 0.88
More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin Va. J Biol Chem (2013) 0.88
The many different cellular functions of MYO7A in the retina. Biochem Soc Trans (2011) 0.88
Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis. Mol Biol Cell (2011) 0.86
Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS One (2015) 0.86
Full-length myosin Va exhibits altered gating during processive movement on actin. Proc Natl Acad Sci U S A (2012) 0.84
Cellular and clinical report of new Griscelli syndrome type III cases. Pigment Cell Melanoma Res (2011) 0.81
Regulated phosphorylation of budding yeast's essential myosin V heavy chain, Myo2p. Mol Biol Cell (2006) 0.80
Rab3D is critical for secretory granule maturation in PC12 cells. PLoS One (2013) 0.78
Two-exon skipping within MLPH is associated with coat color dilution in rabbits. PLoS One (2013) 0.77
The "melanoma-enriched" microRNA miR-4731-5p acts as a tumour suppressor. Oncotarget (2016) 0.75
Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro. Proc Natl Acad Sci U S A (2017) 0.75
Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells. Mol Biol Cell (2016) 0.75
Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes. Nat Commun (2016) 0.75
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (2007) 8.10
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol (2010) 2.98
TDP-43 mutation in familial amyotrophic lateral sclerosis. Ann Neurol (2008) 2.92
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann Surg Oncol (2008) 2.56
Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse. Diabetes (2003) 2.05
Predicted expansion of the claudin multigene family. FEBS Lett (2011) 1.91
The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules. Mol Cell Biol (2002) 1.87
Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis. J Clin Oncol (2009) 1.78
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation. J Clin Invest (2005) 1.75
Granuphilin molecularly docks insulin granules to the fusion machinery. J Cell Biol (2005) 1.66
Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals. J Mol Med (Berl) (2005) 1.62
GBF1, a guanine nucleotide exchange factor for ADP-ribosylation factors, is localized to the cis-Golgi and involved in membrane association of the COPI coat. Traffic (2002) 1.59
Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes (2008) 1.55
The roles of Rab27 and its effectors in the regulated secretory pathways. Cell Struct Funct (2003) 1.52
Clinical features of SCA36: a novel spinocerebellar ataxia with motor neuron involvement (Asidan). Neurology (2012) 1.51
Modular genetic control of sexually dimorphic behaviors. Cell (2012) 1.50
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. Nat Chem Biol (2005) 1.47
A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes. Gastroenterology (2013) 1.47
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys. J Steroid Biochem Mol Biol (2012) 1.38
Whole genome association study of rheumatoid arthritis using 27 039 microsatellites. Hum Mol Genet (2005) 1.36
Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a. Structure (2008) 1.33
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas. Mech Dev (2004) 1.31
Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer. Cancer Res (2008) 1.30
Involvement of Rab27b in the regulated secretion of pituitary hormones. Endocrinology (2002) 1.30
Nestin as a marker for proliferative endothelium in gliomas. Lab Invest (2002) 1.29
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis. Biochem Biophys Res Commun (2004) 1.29
Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats. Diabetes (2004) 1.26
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis. EMBO J (2007) 1.26
Docking is not a prerequisite but a temporal constraint for fusion of secretory granules. Traffic (2008) 1.26
Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane. Mol Biol Cell (2007) 1.24
SLURP-2, a novel member of the human Ly-6 superfamily that is up-regulated in psoriasis vulgaris. Genomics (2003) 1.24
Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. Mol Cell Biol (2002) 1.22
Reactive oxygen species-mediated pancreatic beta-cell death is regulated by interactions between stress-activated protein kinases, p38 and c-Jun N-terminal kinase, and mitogen-activated protein kinase phosphatases. Endocrinology (2008) 1.21
Rab27b is associated with fusiform vesicles and may be involved in targeting uroplakins to urothelial apical membranes. Proc Natl Acad Sci U S A (2003) 1.20
Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a. J Biol Chem (2004) 1.18
Constitutive reactive oxygen species generation from autophagosome/lysosome in neuronal oxidative toxicity. J Biol Chem (2009) 1.17
A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals. J Pharmacol Exp Ther (2011) 1.16
Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: their relation to AD common pathology. Neuropathology (2009) 1.15
A dyad oct-binding sequence functions as a maintenance sequence for the unmethylated state within the H19/Igf2-imprinted control region. J Biol Chem (2002) 1.15
Fragmentation of Golgi apparatus of nigral neurons with alpha-synuclein-positive inclusions in patients with Parkinson's disease. Acta Neuropathol (2006) 1.15
Vacuole-creating protein in neurodegenerative diseases in humans. Neurosci Lett (2003) 1.15
Molecular process in acute liver injury and regeneration induced by carbon tetrachloride. Life Sci (2004) 1.10
Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice. Cell Metab (2006) 1.07
Myosin-Va regulates exocytosis through the submicromolar Ca2+-dependent binding of syntaxin-1A. Mol Biol Cell (2005) 1.05
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice. Am J Pathol (2005) 1.05
Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments. J Neurotrauma (2014) 1.05
Phosphorescent light-emitting iridium complexes serve as a hypoxia-sensing probe for tumor imaging in living animals. Cancer Res (2010) 1.03
Familial amyloid polyneuropathy (Finnish type) in a Japanese family: Clinical features and immunocytochemical studies. J Neurol Sci (2006) 1.02
Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A. J Biol Chem (2003) 1.00
Genomewide linkage analysis of familial prostate cancer in the Japanese population. J Hum Genet (2003) 1.00
Regulation of exocytosis through Ca2+/ATP-dependent binding of autophosphorylated Ca2+/calmodulin-activated protein kinase II to syntaxin 1A. J Neurosci (2002) 1.00
Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury. Nat Commun (2013) 1.00
Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules. J Cell Sci (2005) 0.99
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain. Mol Biol Cell (2006) 0.99
Expression of cutaneous fatty acid-binding protein (C-FABP) in prostate cancer: potential prognostic marker and target for tumourigenicity-suppression. Int J Oncol (2008) 0.99
Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration. Neurosci Lett (2009) 0.98
Cytoplasmic transport signal is involved in phogrin targeting and localization to secretory granules. Traffic (2005) 0.97
Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB. Cancer Res (2006) 0.97
Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB). J Med Chem (2012) 0.96
Identification of a chromogranin A domain that mediates binding to secretogranin III and targeting to secretory granules in pituitary cells and pancreatic beta-cells. Mol Biol Cell (2002) 0.96
Kinetic analyses for species differences in P-glycoprotein-mediated drug transport. J Pharm Sci (2006) 0.96
Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinson's disease. J Neurol Sci (2004) 0.96
Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells. J Clin Neurosci (2009) 0.95
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport. J Pharm Sci (2007) 0.95
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem J (2010) 0.95
Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions. Gene (2004) 0.95
Current status of colorectal endoscopic submucosal dissection in Japan and other Asian countries: progressing towards technical standardization. Dig Endosc (2012) 0.94
Immunoreactivities of p62, an ubiqutin-binding protein, in the spinal anterior horn cells of patients with amyotrophic lateral sclerosis. J Neurol Sci (2006) 0.94
Anterior horn cells with abnormal TDP-43 immunoreactivities show fragmentation of the Golgi apparatus in ALS. J Neurol Sci (2008) 0.94
Overexpression of autocrine motility factor in metastatic tumor cells: possible association with augmented expression of KIF3A and GDI-beta. Lab Invest (2004) 0.94
Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses. Cancer Res (2009) 0.94
p62/sequestosome-1 up-regulation promotes ABT-263-induced caspase-8 aggregation/activation on the autophagosome. J Biol Chem (2013) 0.93
Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse. Mamm Genome (2006) 0.93
Optimal labeling condition of antibodies available for immunofluorescence endoscopy. J Med Invest (2006) 0.93
In vivo gene delivery by cationic tetraamino fullerene. Proc Natl Acad Sci U S A (2010) 0.93
Optineurin in neurodegenerative diseases. Neuropathology (2011) 0.92
Pilot study of neoadjuvant chemotherapy with gemcitabine and oral S-1 for resectable pancreatic cancer. Exp Ther Med (2012) 0.92
Identification of functional marker proteins in the mammalian growth cone. Proc Natl Acad Sci U S A (2009) 0.92
An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. J Neurol Sci (2005) 0.92
Proteasomal non-catalytic subunit PSMD2 as a potential therapeutic target in association with various clinicopathologic features in lung adenocarcinomas. Mol Carcinog (2011) 0.91
Gastrin stimulates the growth of gastric pit cell precursors by inducing its own receptors. Am J Physiol Gastrointest Liver Physiol (2002) 0.91
A new infrared fluorescent-labeling agent and labeled antibody for diagnosing microcancers. Bioorg Med Chem (2003) 0.91
Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes. Traffic (2009) 0.91
Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats. J Steroid Biochem Mol Biol (2012) 0.90