PubRank

Andrew J Morris

Author PubWeight™ 105.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. Dev Cell 2011 2.73
2 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol 2008 2.24
3 Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metab 2011 2.08
4 Phospholipase D. Biochem Cell Biol 2004 2.06
5 Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol 2011 1.81
6 Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A 2010 1.80
7 Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. J Biol Chem 2009 1.78
8 Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect 2012 1.73
9 Integral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions. Biochem J 2005 1.67
10 Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature 2013 1.61
11 Roles for lipid phosphate phosphatases in regulation of cellular signaling. Biochim Biophys Acta 2002 1.59
12 The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning. Development 2003 1.57
13 S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release. Blood 2012 1.47
14 Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs. J Cell Biol 2003 1.47
15 Roles of lysophosphatidic acid in cardiovascular physiology and disease. Biochim Biophys Acta 2008 1.34
16 Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res 2012 1.31
17 Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. J Med Chem 2010 1.28
18 Therapeutic potential of autotaxin/lysophospholipase d inhibitors. Curr Drug Targets 2008 1.27
19 The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. Cancer Res 2003 1.26
20 Lipid phosphate phosphatase 3 enables efficient thymic egress. J Exp Med 2011 1.23
21 Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling. Arterioscler Thromb Vasc Biol 2009 1.23
22 Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. J Nat Prod 2013 1.23
23 Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes. J Cell Biol 2002 1.22
24 Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Mol Endocrinol 2012 1.21
25 Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circ Res 2008 1.20
26 Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. J Nat Prod 2013 1.17
27 Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med 2013 1.15
28 Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation. Mol Biol Cell 2003 1.13
29 Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. Clin Cancer Res 2003 1.12
30 Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo. Br J Pharmacol 2005 1.11
31 Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells. J Biol Chem 2011 1.11
32 Lipids and the exocytotic machinery of eukaryotic cells. Curr Opin Cell Biol 2003 1.11
33 Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions. Clin Sci (Lond) 2011 1.10
34 Lysophosphatidic acid signaling: how a small lipid does big things. Trends Biochem Sci 2003 1.09
35 Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. J Lipid Res 2013 1.09
36 Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. Arterioscler Thromb Vasc Biol 2014 1.08
37 Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance. Diabetes 2013 1.08
38 Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy. Mol Cancer Res 2013 1.07
39 A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Mol Biol Cell 2010 1.07
40 Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem 2003 1.07
41 Cdc42 and ARP2/3-independent regulation of filopodia by an integral membrane lipid-phosphatase-related protein. J Cell Sci 2007 1.06
42 Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration. J Cell Sci 2013 1.06
43 Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun 2013 1.05
44 Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia. Arterioscler Thromb Vasc Biol 2012 1.04
45 PIPKIγ regulates focal adhesion dynamics and colon cancer cell invasion. PLoS One 2011 1.04
46 Identification and functional characterization of a presqualene diphosphate phosphatase. J Biol Chem 2006 1.04
47 Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway. Arterioscler Thromb Vasc Biol 2008 1.02
48 The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. Cell Rep 2012 1.01
49 Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls. Toxicol Appl Pharmacol 2010 1.01
50 Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. J Biol Chem 2011 1.01
51 Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells. J Lipid Res 2003 1.00
52 Phospholipase D in the Golgi apparatus. Biochim Biophys Acta 2009 1.00
53 Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells--implications for tissue regeneration. Stem Cells 2013 0.97
54 Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. Arterioscler Thromb Vasc Biol 2014 0.94
55 Lipin proteins form homo- and hetero-oligomers. Biochem J 2010 0.93
56 Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation. Proc Natl Acad Sci U S A 2012 0.93
57 Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angew Chem Int Ed Engl 2014 0.93
58 The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Nat Prod Res 2013 0.92
59 G-protein-coupled receptor regulation of phospholipase D. Methods Enzymol 2002 0.91
60 Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways. Biochem J 2011 0.91
61 Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. Int J Biochem Cell Biol 2010 0.91
62 Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes. J Neuroinflammation 2014 0.90
63 Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. J Biol Chem 2010 0.90
64 Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Org Lett 2015 0.89
65 Enzymatic analysis of lipid phosphate phosphatases. Methods 2006 0.88
66 Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. FEBS J 2014 0.88
67 Sphingosine 1-phosphate (S1P) regulates glucose-stimulated insulin secretion in pancreatic beta cells. J Biol Chem 2012 0.88
68 Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia 2011 0.88
69 Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. J Biol Chem 2013 0.88
70 Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction. Stem Cells Dev 2013 0.87
71 Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Arterioscler Thromb Vasc Biol 2011 0.87
72 Lack of lipid phosphate phosphatase-3 in embryonic stem cells compromises neuronal differentiation and neurite outgrowth. Dev Dyn 2012 0.85
73 Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet. Biosci Rep 2012 0.85
74 Inorganic double-helix structures of unusually simple lithium-phosphorus species. Angew Chem Int Ed Engl 2012 0.85
75 Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration. FASEB J 2013 0.83
76 Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice. J Am Heart Assoc 2014 0.83
77 Is PRG-1 a new lipid phosphatase? Nat Neurosci 2004 0.83
78 Synergistic effect of anemia and red blood cells transfusion on inflammation and lung injury. Adv Hematol 2012 0.83
79 Translocation of lysophosphatidic acid phosphatase in response to gonadotropin-releasing hormone to the plasma membrane in ovarian cancer cell. Am J Obstet Gynecol 2004 0.83
80 The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid. J Lipid Res 2012 0.82
81 A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem 2014 0.82
82 Bioactive products generated by group V sPLA(2) hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines. Cytokine 2010 0.82
83 Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol 2013 0.82
84 Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. J Nat Prod 2016 0.81
85 Lysophospholipids in coronary artery and chronic ischemic heart disease. Curr Opin Lipidol 2015 0.81
86 A diastereoselective oxa-Pictet-Spengler-based strategy for (+)-frenolicin B and epi-(+)-frenolicin B synthesis. Org Lett 2013 0.81
87 Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction. FEBS J 2005 0.81
88 Pulmonary fibrosis inducer, bleomycin, causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells. Int J Toxicol 2010 0.81
89 Resolving the different silicon clusters in Li12Si7 by 29Si and (6,7)Li solid-state NMR spectroscopy. Angew Chem Int Ed Engl 2011 0.80
90 Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases. Biochem Biophys Res Commun 2012 0.79
91 ARNO but not cytohesin-1 translocation is phosphatidylinositol 3-kinase-dependent in HL-60 cells. J Leukoc Biol 2002 0.79
92 Ab initio structure search and in situ 7Li NMR studies of discharge products in the Li-S battery system. J Am Chem Soc 2014 0.79
93 Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes. J Nutr Biochem 2013 0.79
94 Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues for in vivo mass spectrometric quantification. J Labelled Comp Radiopharm 2013 0.78
95 Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol 2011 0.78
96 The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. PLoS One 2012 0.78
97 Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice. PLoS One 2013 0.78
98 Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice. Environ Health Perspect 2015 0.77
99 Is there a role for intramedullary nails in the treatment of simple pilon fractures? Rationale and preliminary results. Injury 2013 0.76
100 Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4). Org Biomol Chem 2017 0.75
101 Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression. Biochim Biophys Acta 2004 0.75
102 Investigating Sodium Storage Mechanisms in Tin Anodes: A Combined Pair Distribution Function Analysis, Density Functional Theory and Solid-State NMR Approach. J Am Chem Soc 2017 0.75
103 Emerging roles of xenobiotic detoxification enzymes in metabolic diseases. Rev Environ Health 2016 0.75
104 Experimental and theoretical evaluation of the stability of true MOF polymorphs explains their mechanochemical interconversions. J Am Chem Soc 2017 0.75
105 Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8". Org Lett 2015 0.75