Published in Development on July 01, 2002
Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res (2009) 3.66
The genetics of early telencephalon patterning: some assembly required. Nat Rev Neurosci (2008) 2.40
Early steps in the development of the forebrain. Dev Cell (2004) 2.34
Frontal cortex subdivision patterning is coordinately regulated by Fgf8, Fgf17, and Emx2. J Comp Neurol (2008) 1.90
Shadows of complexity: what biological networks reveal about epistasis and pleiotropy. Bioessays (2009) 1.82
Deriving excitatory neurons of the neocortex from pluripotent stem cells. Neuron (2011) 1.62
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev (2008) 1.40
Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts. Bone (2012) 1.38
The way Wnt works: components and mechanism. Growth Factors (2012) 1.37
Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. Neural Dev (2007) 1.36
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex (2007) 1.33
3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). Gene Expr Patterns (2008) 1.24
Smad signaling in skeletal development and regeneration. Cytokine Growth Factor Rev (2009) 1.17
FGF8 acts as a classic diffusible morphogen to pattern the neocortex. Development (2010) 1.13
Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A (2007) 1.12
Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proc Natl Acad Sci U S A (2006) 1.06
Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling. Development (2008) 1.06
Wnt signaling in vertebrate neural development and function. J Neuroimmune Pharmacol (2012) 1.00
Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn (2010) 1.00
Regulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursors. PLoS One (2010) 0.97
Wnt signaling and forebrain development. Cold Spring Harb Perspect Biol (2012) 0.97
Genomic perspectives of transcriptional regulation in forebrain development. Neuron (2015) 0.97
BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. Dev Biol (2013) 0.95
A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium. PLoS Biol (2010) 0.94
Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex. Neuron (2014) 0.93
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest (2015) 0.91
Disturbed Wnt Signalling due to a Mutation in CCDC88C Causes an Autosomal Recessive Non-Syndromic Hydrocephalus with Medial Diverticulum. Mol Syndromol (2010) 0.88
Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation. ASN Neuro (2011) 0.87
The cortical hem regulates the size and patterning of neocortex. Development (2014) 0.86
Inhibition of Drosophila Wg signaling involves competition between Mad and Armadillo/beta-catenin for dTcf binding. PLoS One (2008) 0.86
Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus. Cereb Cortex (2012) 0.83
The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex (2012) 0.81
Transcriptional and epigenetic mechanisms of early cortical development: An examination of how Pax6 coordinates cortical development. J Comp Neurol (2015) 0.78
Subset of early radial glial progenitors that contribute to the development of callosal neurons is absent from avian brain. Proc Natl Acad Sci U S A (2015) 0.76
The Good and Bad of β-Catenin in Kidney Development and Renal Dysplasia. Front Cell Dev Biol (2015) 0.75
Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry. Mol Neuropsychiatry (2017) 0.75
Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun (2017) 0.75
Only scratching the cell surface: extracellular signals in cerebrum development. Curr Opin Genet Dev (2013) 0.75
Tuning of neocortical astrogenesis rates by Emx2 in neural stem cells. Neural Regen Res (2015) 0.75
Nanog safeguards pluripotency and mediates germline development. Nature (2007) 13.01
Inactivation of the Fto gene protects from obesity. Nature (2009) 5.61
The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome. Nat Genet (2007) 4.63
The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster. Mamm Genome (2002) 4.06
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Cell Stem Cell (2009) 3.27
Ftm is a novel basal body protein of cilia involved in Shh signalling. Development (2007) 2.25
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev (2002) 2.10
The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J (2002) 1.57
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat Neurosci (2013) 1.57
Pallister-Hall syndrome phenotype in mice mutant for Gli3. Hum Mol Genet (2002) 1.49
The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol (2007) 1.45
Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear. Development (2007) 1.37
Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci (2008) 1.30
Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway. FASEB J (2007) 1.26
Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation. Mol Cell Neurosci (2008) 1.20
Shedding light on an old mystery: thalidomide suppresses survival pathways to induce limb defects. Cell Cycle (2008) 1.17
Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Dev Biol (2006) 1.10
A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon. Dev Biol (2003) 1.08
Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism. Mol Endocrinol (2004) 1.05
Critical involvement of hydrogen peroxide in exercise-induced up-regulation of endothelial NO synthase. Cardiovasc Res (2005) 1.04
FTO levels affect RNA modification and the transcriptome. Eur J Hum Genet (2012) 1.00
Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense. Mol Pharm (2009) 0.97
Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing. Development (2011) 0.96
Expression of the zebrafish Iroquois genes during early nervous system formation and patterning. J Comp Neurol (2005) 0.95
Bmp, Fgf and Wnt signalling in programmed cell death and chondrogenesis during vertebrate limb development: the role of Dickkopf-1. Int J Dev Biol (2002) 0.94
A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud. Dev Biol (2009) 0.94
The molecular basis of Pallister Hall associated polydactyly. Hum Mol Genet (2007) 0.93
Comparative proteomic analysis reveals a function of the novel death receptor-associated protein BRE in the regulation of prohibitin and p53 expression and proliferation. Proteomics (2006) 0.89
Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning. Dev Dyn (2005) 0.88
The ciliary protein Ftm is required for ventricular wall and septal development. PLoS One (2013) 0.87
Organization of Iroquois genes in fish. Dev Genes Evol (2004) 0.87
Thalidomide induces limb anomalies by PTEN stabilization, Akt suppression, and stimulation of caspase-dependent cell death. Mol Cell Biol (2008) 0.86
Cardiospecific overexpression of the prostaglandin EP3 receptor attenuates ischemia-induced myocardial injury. Circulation (2005) 0.85
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis. Exp Dermatol (2007) 0.84
The Fused toes (Ft) mouse mutation causes anteroposterior and dorsoventral polydactyly. Dev Biol (2002) 0.83
Primordial germ cell proliferation is impaired in Fused Toes mutant embryos. Dev Biol (2010) 0.81
The Dkk1 dose is critical for eye development. Dev Biol (2011) 0.80
Immunoglobulin-like transcripts as risk genes for autoimmunity. Ann N Y Acad Sci (2007) 0.80
The fused toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads in mice. Biol Reprod (2011) 0.79
Laminar and subcellular heterogeneity of GLAST and GLT-1 immunoreactivity in the developing postnatal mouse hippocampus. J Comp Neurol (2014) 0.79
The regulation of Dkk1 expression during embryonic development. Dev Biol (2010) 0.78